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David D. Manning · SciRah

Researcher profile · Semantic Scholar

David D. Manning

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David D. Manning — researcher profile on SciRah

h-index: 17
Works: 31
Citations: 1,138

Most-cited papers

Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria.
D. Yanez, David D. Manning, A. Cooley, W. Weidanz +1 more
1996Journal of Immunology290 citations
Semantic Scholar
Synthesis of Sulfated Neoglycopolymers: Selective P-Selectin Inhibitors
David D. Manning, Xin Hu, P. Beck, L. Kiessling
1997123 citations
Semantic Scholar
A Library Approach to the Discovery of Small Molecules That Recognize RNA: Use of a 1,3-Hydroxyamine Motif as Core
C. Wong, M. Hendrix, David D. Manning, Christoph Rosenbohm +1 more
1998105 citations
Semantic Scholar
Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria.
H. C. van der Heyde, M. Elloso, Wun-Ling Chang, M. Kaplan +2 more
1995Journal of Immunology76 citations
Semantic Scholar
Neoglycopolymer inhibitors of the selectins
David D. Manning, L. Strong, Xin Hu, P. Beck +1 more
199763 citations
Semantic Scholar
Human gamma delta T cell subset-proliferative response to malarial antigen in vitro depends on CD4+ T cells or cytokines that signal through components of the IL-2R.
M. Elloso, H. C. van der Heyde, A. Troutt, David D. Manning +1 more
1996Journal of Immunology61 citations
Semantic Scholar
γδ T-Cell Function in Pathogenesis of Cerebral Malaria in Mice Infected with Plasmodium bergheiANKA
D. Yanez, J. Batchelder, H. C. van der Heyde, David D. Manning +1 more
1999Infection and Immunity57 citations Open access
Semantic Scholar
Role of CD4+ T cells in the expansion of the CD4-, CD8- gamma delta T cell subset in the spleens of mice during blood-stage malaria.
H. C. van der Heyde, David D. Manning, William P. Weidanz
1993Journal of Immunology54 citations Open access
Semantic Scholar
Selectin-Saccharide Interactions: Revealing Structure-Function Relationships with Chemical Synthesis
David D. Manning, C. Bertozzi, N. Pohl, S. Rosen +1 more
199529 citations
Semantic Scholar
Tin-mediated phosphorylation: Synthesis and selectin binding of a phospho Lewis a analog
David D. Manning, C. Bertozzi, S. Rosen, L. Kiessling
199627 citations
Semantic Scholar
Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors.
J. Wityak, Kevin F. Mcgee, Michael P Conlon, Ren-Hua Song +35 more
2015Journal of Medicinal Chemistry26 citations
Semantic Scholar
Partial agonism of 5-HT3 receptors: a novel approach to the symptomatic treatment of IBS-D.
N. Moore, B. J. Sargent, David D. Manning, P. Guzzo
2013ACS Chemical Neuroscience24 citations Open access
Semantic Scholar
2,3,4,5-Tetrahydro-1H-pyrido[2,3-b and e][1,4]diazepines as inhibitors of the bacterial enoyl ACP reductase, FabI.
J. Ramnauth, M. Surman, P. Sampson, Bryan T. Forrest +11 more
2009Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Synthesis of sulfated trisaccharide ligands for the selectins
W. J. Sanders, David D. Manning, Kathryn M. Koeller, L. Kiessling
199724 citations
Semantic Scholar
Synthesis and SAR of vinca alkaloid analogues.
M. Voss, Jeffery M. Ralph, D. Xie, David D. Manning +12 more
2009Bioorganic & Medicinal Chemistry Letters23 citations
Semantic Scholar
Discovery of 2-substituted benzoxazole carboxamides as 5-HT3 receptor antagonists.
Zhicai Yang, David J. Fairfax, J. Maeng, Liaqat Masih +22 more
2010Bioorganic & Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
The effects of interleukin-15 on human γδ T cell responses to Plasmodium falciparum in vitro
M. Elloso, M. Wallace, David D. Manning, W. Weidanz
199819 citations Open access
Semantic Scholar
Derivation of gnotobiotic ferrets: perinatal diet and hand-rearing requirements.
David D. Manning, J. Bell
1990Laboratory animal science17 citations
Semantic Scholar
Carboxylate bioisosteres of pregabalin.
Jacob B. Schwarz, N. Colbry, Zhi-Jian Zhu, Brian J. Nichelson +17 more
2006Bioorganic & Medicinal Chemistry Letters14 citations
Semantic Scholar
CSTI-300 (SMP-100); a Novel 5-HT3 Receptor Partial Agonist with Potential to Treat Patients with Irritable Bowel Syndrome or Carcinoid Syndrome
Alexander Roberts, G. Grafton, Andrew D. Powell, K. Brock +13 more
2020Journal of Pharmacology and Experimental Therapeutics13 citations Open access
Semantic Scholar
Preparation of (r)-(+)-7-oxabicyclo[2.2.1]hept-5-ene-exo-2-carboxylic acid, a precursor to substrates for the ring opening metathesis polymerization
Christine M. Schueller, David D. Manning, L. Kiessling
199612 citations
Semantic Scholar
Organozirconium Chemistry onCyclosporin: A Novel Process for the Highly Stereoselective Synthesisof (E)-ISA247 (Voclosporin) and CloseAnalogues
J. Maeng, Zhicai Yang, David D. Manning, Liaqat Masih +4 more
20129 citations
Semantic Scholar
Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome.
David D. Manning, C. Cioffi, A. Usyatinsky, Kevin T. Fitzpatrick +16 more
2011Bioorganic & Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
The discovery of diazepinone-based 5-HT3 receptor partial agonists.
David D. Manning, Cheng Guo, Zhenjun Zhang, Kristen N. Ryan +9 more
2014Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
Selectin‐Saccharide Interactions: Revealing Structure‐Function Relationships with Chemical Synthesis.
David D. Manning, C. Bertozzi, N. Pohl, S. Rosen +1 more
19965 citations
Semantic Scholar
Neoglycopolymer Inhibitors of the Selectins.
David D. Manning, L. Strong, X. Hu, P. Beck +1 more
19973 citations
Semantic Scholar
5-HT3 Receptor Partial Agonist Modulation, a Novel Approach to the Treatment of Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)
David D. Manning, Jonathan D. Wierschke, N. Barnes, N. Moore
20112 citations Open access
Semantic Scholar
Synthesis of Sulfated Trisaccharide Ligands for the Selectins.
W. J. Sanders, David D. Manning, Kathryn M. Koeller, L. Kiessling
19982 citations
Semantic Scholar
A Simple Strategy for the Preparation of 6-Substituted 3H-Benzoxazol-2-ones and 3H-Benzothiazol-2-ones
R. Deorazio, J. Maeng, David D. Manning, B. Sherer +2 more
20111 citations
Semantic Scholar
Antibody-Drug Conjugates: Catalysts for Chemistry
David D. Manning
20170 citations
Semantic Scholar
Preparation of (R)‐(+)‐7‐Oxabicyclo(2.2.1)hept‐5‐ene‐exo‐2‐carboxylic Acid, a Precursor to Substrates for the Ring Opening Metathesis Polymerization.
Christine M. Schueller, David D. Manning, L. Kiessling
19970 citations
Semantic Scholar

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