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Shi-Kun He · SciRah

Researcher profile · Semantic Scholar

Shi-Kun He

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Shi-Kun He — researcher profile on SciRah

h-index: 38
Works: 147
Citations: 5,254

Most-cited papers

Autophagy and autophagy-related proteins in cancer
Xiaohua Li, Shi-Kun He, B. Ma
2020Molecular Cancer1,515 citations Open access
Semantic Scholar
alphaB-crystallin regulation of angiogenesis by modulation of VEGF.
S. Kase, Shi-Kun He, S. Sonoda, Mizuki Kitamura +5 more
2010Blood161 citations Open access
Semantic Scholar
In vivo models of proliferative vitreoretinopathy
R. Agrawal, Shi-Kun He, C. Spee, Jing Z. Cui +2 more
2007Nature Protocols118 citations
Semantic Scholar
Transforming growth factor β2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: Regulation by extracellular matrix proteins and hepatocyte growth factor
Maria-Andreea Gamulescu, You-Xin Chen, Shi-Kun He, C. Spee +3 more
200683 citations
Semantic Scholar
Deficiency of αB crystallin augments ER stress induced apoptosis by enhancing mitochondrial dysfunction
G. Dou, P. Sreekumar, C. Spee, Shi-Kun He +3 more
2012Free Radical Biology & Medicine79 citations Open access
Semantic Scholar
Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy
K. Ishikawa, Shi-Kun He, Hiroto Terasaki, H. Nazari +4 more
2015Scientific Reports78 citations Open access
Semantic Scholar
MMP-2 AND MMP-9 SECRETION BY RPE IS STIMULATED BY ANGIOGENIC MOLECULES FOUND IN CHOROIDAL NEOVASCULAR MEMBRANES
S. Hoffmann, Shi-Kun He, M. Ehren, S. Ryan +2 more
2006Retina77 citations
Semantic Scholar
Regulated secretion of complement factor H by RPE and its role in RPE migration
Y. Kim, Shi-Kun He, S. Kase, Mizuki Kitamura +2 more
2009Graefe's Archive for Clinical and Experimental Ophthalmology75 citations Open access
Semantic Scholar
Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells
Shi-Kun He, J. Yaung, Y. Kim, E. Barrón +2 more
2008Graefe's Archive for Clinical and Experimental Ophthalmology73 citations
Semantic Scholar
Review: Epigenetic mechanisms in ocular disease
Shi-Kun He, Xiaohua Li, N. Chan, D. Hinton
2013Molecular Vision70 citations
Semantic Scholar
SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization
Huiming Zhang, Shi-Kun He, C. Spee, K. Ishikawa +1 more
2015Cytokine61 citations Open access
Semantic Scholar
Sequential induction of angiogenic growth factors by TNF-alpha in choroidal endothelial cells.
M. Hangai, Shi-Kun He, S. Hoffmann, Jennifer I. Lim +2 more
2006Journal of Neuroimmunology59 citations
Semantic Scholar
Connective tissue growth factor as a mediator of intraocular fibrosis.
Shi-Kun He, You-Xin Chen, R. Khankan, E. Barrón +5 more
2008Investigative Ophthalmology and Visual Science57 citations Open access
Semantic Scholar
Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9
Jing Xu, Danhong Zhu, S. Sonoda, Shi-Kun He +3 more
2012Angiogenesis56 citations Open access
Semantic Scholar
Angiofibrotic response to VEGF inhibition in diabetic retinal detachment. Report No 1
E. Sohn, Shi-Kun He, L. Kim, H. Salehi-Had +5 more
2012A M A Archives of Ophthalmology46 citations Open access
Semantic Scholar
IL18 is not therapeutic for neovascular age-related macular degeneration
Yoshio Hirano, T. Yasuma, Takeshi Mizutani, B. Fowler +20 more
2014Nature Medicine45 citations Open access
Semantic Scholar
Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization.
Shi-Kun He, Yi Ding, Jiehao Zhou, V. Krasnoperov +5 more
2005Investigative Ophthalmology and Visual Science44 citations
Semantic Scholar
The critical role of the interplays of EphrinB2/EphB4 and VEGF in the induction of angiogenesis
Enming Du, Xia Li, Si-Yu He, Xiaohua Li +1 more
2020Molecular Biology Reports43 citations
Semantic Scholar
Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion.
Man-Lin Jin, J. Yaung, R. Kannan, Shi-Kun He +2 more
2005Investigative Ophthalmology and Visual Science43 citations Open access
Semantic Scholar
Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor.
M. Gamulescu, You-Xin Chen, Shi-Kun He, C. Spee +3 more
2006Experimental Eye Research42 citations
Semantic Scholar
A selective cyclic integrin antagonist blocks the integrin receptors αvβ3 and αvβ5 and inhibits retinal pigment epithelium cell attachment, migration and invasion
S. Hoffmann, Shi-Kun He, Man-Lin Jin, M. Ehren +3 more
2005BMC Ophthalmology39 citations Open access
Semantic Scholar
RPE epithelial-mesenchymal transition plays a critical role in the pathogenesis of proliferative vitreoretinopathy
Xiaohua Li, Mingwei Zhao, Shi-Kun He
2020Annals of Translational Medicine36 citations Open access
Semantic Scholar
Regulation of fibronectin-EDA through CTGF domain-specific interactions with TGFβ2 and its receptor TGFβRII.
R. Khankan, N. Oliver, Shi-Kun He, S. Ryan +1 more
2011Investigative Ophthalmology and Visual Science36 citations Open access
Semantic Scholar
Soluble EphB4 inhibits PDGF-induced RPE migration in vitro
Shi-Kun He, Santhosh K. P. Kumar, Peng Zhou, V. Krasnoperov +3 more
2009Investigative Ophthalmology and Visual Science35 citations Open access
Semantic Scholar
Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age‐related macular degeneration
Jing Xu, Danhong Zhu, Shi-Kun He, C. Spee +2 more
2011The FASEB Journal32 citations Open access
Semantic Scholar
Inhibition of DNA Methylation and Methyl-CpG-Binding Protein 2 Suppresses RPE Transdifferentiation: Relevance to Proliferative Vitreoretinopathy.
Shi-Kun He, E. Barrón, K. Ishikawa, Hossein Nazari Khanamiri +6 more
2015Investigative Ophthalmology and Visual Science29 citations Open access
Semantic Scholar
The essential role of N6-methyladenosine RNA methylation in complex eye diseases
Xiaohua Li, B. Ma, Wen-Fang Zhang, Zong-Ming Song +8 more
2022Genes and Diseases28 citations Open access
Semantic Scholar
Attenuation of Choroidal Neovascularization by Histone Deacetylase Inhibitor
N. Chan, Shi-Kun He, C. Spee, K. Ishikawa +1 more
2015PLoS ONE28 citations Open access
Semantic Scholar
Distinct Role of Lycium barbarum L. Polysaccharides in Oxidative Stress-Related Ocular Diseases
Yali Niu, Guoheng Zhang, Xiaojia Sun, Shi-Kun He +1 more
2023Pharmaceuticals27 citations Open access
Semantic Scholar
An Updated Review of the Epigenetic Mechanism Underlying the Pathogenesis of Age-related Macular Degeneration
Xiaohua Li, Shi-Kun He, Mingwei Zhao
2020Aging and Disease21 citations Open access
Semantic Scholar
The critical role of m6A methylation in the pathogenesis of Graves' ophthalmopathy
Li Zhu, Siyan Li, Shi-Kun He, Qizhe Tong +11 more
2020Eye and Vision20 citations Open access
Semantic Scholar
Early onset vitreous amyloidosis in familial amyloidotic polyneuropathy with a transthyretin Glu54Gly mutation is associated with elevated vitreous VEGF
T. O'Hearn, A. Fawzi, Shi-Kun He, N. Rao +1 more
2007British Journal of Ophthalmology20 citations Open access
Semantic Scholar
Apoptosis and Angiofibrosis in Diabetic Tractional Membranes after VEGF Inhibition: Results of a Prospective Trial. Report no. 2
C. Jiao, D. Eliott, C. Spee, Shi-Kun He +4 more
2017Retina19 citations Open access
Semantic Scholar
Essential Role of Multi-Omics Approaches in the Study of Retinal Vascular Diseases
Yi-Yang Lei, Ju-Qing Guo, Shi-Kun He, Hua Yan
2022Cells15 citations Open access
Semantic Scholar
Histone deacetylase inhibitor attenuates experimental fungal keratitis in mice
Xiaohua Li, Min Yuan, Ruijie Yin, Xiao-Hui Liu +4 more
2019Scientific Reports15 citations Open access
Semantic Scholar
Thrombospondin-1 expression in RPE and choroidal neovascular membranes.
Shi-Kun He, F. Incardona, Man-Lin Jin, S. Ryan +1 more
2006Yan ke xue bao = Eye science13 citations
Semantic Scholar
Potential Impact of N6-Methyladenosine RNA Methylation on Vision Function and the Pathological Processes of Ocular Diseases: New Discoveries and Future Perspectives.
Xiaohua Li, B. Ma, Meng-Yu Liao, Lingke Li +5 more
2022Frontiers in Bioscience8 citations Open access
Semantic Scholar
MeCP2‐421‐mediated RPE epithelial‐mesenchymal transition and its relevance to the pathogenesis of proliferative vitreoretinopathy
Xiaohua Li, Xia Li, Shi-Kun He, Mingwei Zhao
2020Journal of Cellular and Molecular Medicine8 citations Open access
Semantic Scholar
A porous B/L acid zeolite-based catalyst regulates and controls the degradation of biomass carbohydrates to produce levulinic acid/esters
Ronghua Zhang, Shi-Kun He, Fei Wang, Bo Cai +2 more
2024Chemistry Physics6 citations
Semantic Scholar
Proteopathy Linked to Exon-Skipping Isoform of RGR-Opsin Contributes to the Pathogenesis of Age-Related Macular Degeneration
Chi Ren, Haoran Cui, Xuan Bao, Lvzhen Huang +3 more
2023Investigative Ophthalmology and Visual Science6 citations Open access
Semantic Scholar
Endoplasmic reticulum stress as a novel target to inhibit transdifferentiation of human retinal pigment epithelial cells.
Sha Ouyang, D. Ji, Shi-Kun He, Xiao-Bo Xia
2022Frontiers in Bioscience6 citations Open access
Semantic Scholar
Human RGR Gene and Associated Features of Age-related Macular Degeneration Revealed in Models of Retina-Choriocapillaris Atrophy.
X. Bao, Zhaoxia Zhang, Yanjiang Guo, Christopher Buser +10 more
2021American Journal of Pathology6 citations Open access
Semantic Scholar
[The effect of oxidative stress on retinal pigment epithelial cell migration].
Yan Jiang, Shi-Kun He
2005[Zhonghua yan ke za zhi] Chinese journal of ophthalmology5 citations
Semantic Scholar
Longitudinal Blood Transcriptome Analysis Reveals Dynamic Gene Expression Patterns in Patients With Allergic Rhinitis Following House Dust Mite Subcutaneous Immunotherapy
Chang Liu, Shi-Kun He, Jin-Xiu Zhang, Jin Zhu +4 more
2025Clinical and Experimental Allergy3 citations
Semantic Scholar
Is MeCP2 a Gene Suppressor or Activator
Shi-Kun He, HaikeGuoMD
20142 citations Open access
Semantic Scholar
[Aging and age-related macular degeneration].
Shi-Kun He, Yan Jiang
2006[Zhonghua yan ke za zhi] Chinese journal of ophthalmology2 citations
Semantic Scholar
Inhibition of laser induced rats choroidal neovascularization by intravitreous injection of sEphB4-HSA
Shi-Kun He, Sha Ouyang, Xiaohua Li, B. Ma
2020Annals of Translational Medicine1 citations Open access
Semantic Scholar
The effects of Pigment Epithelium-Derived Factor on Epithelial-to-mesenchymal transition of the retinal pigment epithelium induced by TGF-β.
S. Ouyang, Shi-Kun He, C. Spee, D. Hinton
20171 citations
Semantic Scholar
Angiofibrotic Response to Bevacizumab on Fibrovascular Membranes in Proliferative Diabetic Retinopathy
C. Jiao, C. Spee, Shi-Kun He, R. Mullins +3 more
20141 citations
Semantic Scholar
The effects of SIRT1 on hypoxia induced by cobalt chloride in human fetal retinal pigment epithelial cells
Huiming Zhang, Shi-Kun He, C. Spee, D. Hinton
20141 citations
Semantic Scholar

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