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M. Griffin · SciRah

Researcher profile · Semantic Scholar

M. Griffin

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M. Griffin — researcher profile on SciRah

h-index: 9
Works: 69
Citations: 389

Most-cited papers

The design of fluorescent probes which bind to the active centre of guanidinobenzoatase. Application to the location of cells possessing this enzyme.
Frank S. Steven, M. Griffin, R. K. Al-Ahmad
1985European Journal of Biochemistry42 citations Open access
Semantic Scholar
Inhibition of human and bovine sperm acrosin by divalent metal ions. Possible role of zinc as a regulator of acrosin activity.
Frank S. Steven, M. Griffin, E. Chantler
1982International Journal of Andrology40 citations Open access
Semantic Scholar
A trypsin-like neutral protease on Ehrlich ascites cell surfaces: its role in the activation of tumour-cell zymogen of collagenase.
Frank S. Steven, M. Griffin, S. Itzhaki, A. Al-Habib
1980British Journal of Cancer29 citations Open access
Semantic Scholar
Disulphide exchange reactions in the control of enzymic activity. Evidence for the participation of dimethyl disulphide in exchanges.
Frank S. Steven, M. Griffin, Ronald H. Smith
1981European Journal of Biochemistry26 citations Open access
Semantic Scholar
Aggregation of fibrinogen molecules by metal ions
F. Steven, M. Griffin, B. S. Brown, T. Hulley
198219 citations
Semantic Scholar
Evidence for inhibitors of the cell surface protease guanidinobenzoatase.
Frank S. Steven, M. Griffin, T. L. H. Wong, S. Itzhaki
1986Journal of enzyme inhibition (Print)16 citations
Semantic Scholar
Evidence for metal inhibition of tumour membrane-bound neutral protease and the control of tumour-induced target cell cytolysis.
Frank S. Steven, T. Hulley, M. Griffin, S. Itzhaki
1982British Journal of Cancer15 citations Open access
Semantic Scholar
EVIDENCE FOR CARRIAGE OF SILVER BY SULPHADIMIDINE: HAEMOLYSIS OF HUMAN ERYTHROCYTES
P. Ballinger, B. S. Brown, M. Griffin, F. Steven
1982British Journal of Pharmacology14 citations Open access
Semantic Scholar
The role of inhibitors in the fluorescent staining of benign naevus and malignant melanoma cells with 9-amino acridine and acridine orange.
Frank S. Steven, U. Suresh, T. L. H. Wong, M. Griffin
1987Journal of enzyme inhibition (Print)10 citations
Semantic Scholar
Evidence for the functional similarity between tumour cell surface guanidinobenzoatase and tissue type plasminogen activator.
Frank S. Steven, M. Griffin, S. Cederholm-Williams, W. Mangel +1 more
1991Anticancer Research9 citations
Semantic Scholar
Inhibition properties of Sepharose-bound trypsin and a protease on the surface of Ehrlich ascites tumour cells.
F. Steven, M. Griffin, G. Itzhaki, A. Al-Habib
1981Biochimica et Biophysica Acta9 citations
Semantic Scholar
Studies on the molecular mechanism of mersalyl and 4-aminophenylmercuric acetate re-activation of trypsin-thiol complexes.
Frank S. Steven, M. Griffin
1980European Journal of Biochemistry9 citations Open access
Semantic Scholar
Biphasic kinetics of metal ion reactivation of trypsin-thiol complexes.
Frank S. Steven, Vladimir Podrazký, A. Al-Habib, M. Griffin
1979Biochimica et Biophysica Acta9 citations
Semantic Scholar
Inhibition of free and bound trypsin-like enzymes.
Frank S. Steven, M. Griffin, S. Itzhaki
2005European Journal of Biochemistry8 citations
Semantic Scholar
Inhibition of guanidinobenzoatase: evidence for multiple forms of this protease on different tumour cells.
Frank S. Steven, M. Griffin, A. Freemont, J. Johnson
1988Journal of enzyme inhibition (Print)8 citations
Semantic Scholar
Inhibition of guanidinobenzoatase by a substrate for trypsin-like enzymes.
Frank S. Steven, M. Griffin, W. Mangel, H. Maier +1 more
1988Journal of enzyme inhibition (Print)8 citations
Semantic Scholar
Direct evidence for the cell surface location of a protease-inhibitor complex on intact leukaemia cells.
Frank S. Steven, M. Griffin
1990Journal of enzyme inhibition (Print)7 citations
Semantic Scholar
Design of fluorescent probes for an enzyme on the surface of tumour cells.
Frank S. Steven, M. Griffin, R. K. Al-Ahmad
1986Journal of Chromatography A7 citations
Semantic Scholar
INHIBITION OF TRYPSIN AND PAPAIN BY SODIUM AUROTHIOMALATE MEDIATED BY EXCHANGE REACTIONS
M. Griffin, Frank S. Steven
1982British Journal of Pharmacology7 citations Open access
Semantic Scholar
beta-Naphthylamidase activity of the cell surface of Ehrlich ascites cells. Reversible control of enzyme activity by metal ions and thiols.
A. Short, Frank S. Steven, M. Griffin, S. Itzhaki
1981British Journal of Cancer7 citations Open access
Semantic Scholar
Further evidence for different isoenzymic forms of a cell surface protease, guanidinobenzoatase, associated with tumours.
Frank S. Steven, M. Griffin, D. Blakey, I. Talbot +2 more
1992Anticancer Research6 citations
Semantic Scholar
Temporary competitive inhibition of a tumour cell surface protease as a protective mechanism in the preparation of the membrane bound native enzyme in the presence of excess cytoplasmic inhibitors.
Frank S. Steven, M. Griffin, H. Maier
1991Journal of enzyme inhibition (Print)6 citations
Semantic Scholar
Studies on the activity of a protease associated with cells at the advancing edge of human tumour masses in frozen sections.
Frank S. Steven, M. Griffin, H. Maier, H. Weidauer +2 more
1988British Journal of Cancer6 citations Open access
Semantic Scholar
GB (guanidinobenzoatase) cell surface protease and serum inhibitors in colorectal neoplasia
Frank S. Steven, M. Griffin, I. Talbot
1992Journal of Pathology5 citations
Semantic Scholar
A fluorescent study of ligands for guanidinobenzoatase, a protease associated with tumour cells.
F. Steven, M. Griffin, L. A. Williams, G. Feichter
1988Anticancer Research5 citations
Semantic Scholar
Evidence for exchange of inhibitors which bind to the active site of trypsin. Displacement of one inhibitor with a competitive inhibitor.
Frank S. Steven, M. Griffin
1981Biochimica et Biophysica Acta5 citations
Semantic Scholar
Inhibition of elastase and fibrinolysin by reducing and oxidizing agents [proceedings].
Frank S. Steven, M. Griffin
1980Biochemical Society Transactions5 citations
Semantic Scholar
Targeting adriamycin to tumour cells by means of an affinity ligand; a model system for drug delivery.
F. Steven, M. Griffin, L. A. Williams, H. Ali +1 more
1989Anticancer Research4 citations
Semantic Scholar
The inhibition of a tumour cell surface protease in vivo and its re-activation by oxidation.
Frank S. Steven, H. Ali, M. Griffin
1988British Journal of Cancer4 citations Open access
Semantic Scholar
Further inhibition studies on guanidinobenzoatase, a trypsin-like enzyme associated with tumour cells.
Frank S. Steven, M. Griffin, T. L. H. Wong, R. Yasmin +1 more
1987Journal of enzyme inhibition (Print)4 citations
Semantic Scholar
Fluorescent inhibitors of a cell surface protease used to locate leukaemia cells in kidney sections.
Frank S. Steven, M. Griffin, T. L. H. Wong, H. Jackson +1 more
1987Journal of enzyme inhibition (Print)4 citations
Semantic Scholar
Co-stacking of propidium iodide on 9-aminoacridine at the active centre of guanidinobenzoatase on tumour cells
F. Steven, M. Griffin, T. L. H. Wong, H. Ali
19864 citations
Semantic Scholar
Evidence for distinct isoenzymic forms of a cell surface protease on normal colonic cells and on carcinoma cells from the same colon.
Frank S. Steven, M. Griffin, I. Talbot
1991Anticancer Research3 citations
Semantic Scholar
The targeting of agmatine-liganded mitomycin C to an enzyme on the surface of tumour cells.
Frank S. Steven, M. Griffin, I. Talbot
1990Anticancer Research3 citations
Semantic Scholar
The presence of both a latent proteinase and an inhibitor in extracts of bovine nasal cartilage and aorta
F. Steven, J. Bartholomew, M. Griffin, John C. Anderson
19813 citations
Semantic Scholar
Labelling of tumour cells with a biotinylated inhibitor of a cell surface protease.
Frank S. Steven, M. Griffin, L. A. Williams, Noel W. Clarke +1 more
1991Journal of enzyme inhibition (Print)2 citations
Semantic Scholar
Guanidinobenzoatase on the surface of tumour cells
F. Steven, R. K. Al-Ahmad, M. Griffin, George Williams +1 more
19832 citations
Semantic Scholar
EVIDENCE FOR THE CARRIAGE OF SILVER BY SULPHADIMIDINE: INHIBITION OF PROTEOLYTIC ENZYMES
P. Ballinger, M. Griffin, S. Itzhaki, Frank S. Steven
1982British Journal of Pharmacology2 citations Open access
Semantic Scholar
Interaction of alpha, beta-diethyl stilbestrol 4,4'-bisphosphate with arginyl substrates resulting in apparent inhibition of trypsin and thrombin.
Frank S. Steven, M. Griffin, Timothy P. Hulley, Peter Brooman
1982European Journal of Biochemistry2 citations Open access
Semantic Scholar
Affinity preparation of a protein inhibitor recognising a cell surface protease.
Frank S. Steven, M. Griffin, J. Bell, I. Talbot
1993Journal of enzyme inhibition (Print)1 citations
Semantic Scholar
Observations on the conformational changes in the structure of a cell surface protease, followed by its ability to be recognised by competitive and non-competitive inhibitors.
Frank S. Steven, M. Griffin, M. Anees, E. Benbow
1992Journal of enzyme inhibition (Print)1 citations
Semantic Scholar
Demonstration of a cell surface protease isoenzyme specific for breast carcinoma cells which is not present on normal breast cells
F. Steven, M. Griffin, I. Ellis, J. Bell +1 more
19921 citations
Semantic Scholar
Studies on the interaction and exchange of inhibitors and proteases on the surface of tumour cells in frozen sections.
Frank S. Steven, M. Griffin, Neil J. Bulleid, H. Maier +1 more
1991Anticancer Research1 citations
Semantic Scholar
Evidence for cells possessing t-PA like activity in smears obtained from patients with oral squamous cell carcinoma.
Frank S. Steven, M. Griffin, J. Zoeller, H. Maier
1990Anticancer Research1 citations
Semantic Scholar
Inhibition of trypsin-like enzymes on cells with rhodamine-aprotinin.
Frank S. Steven, M. Griffin, L. A. Williams, A. Freemont +2 more
1989Journal of enzyme inhibition (Print)1 citations
Semantic Scholar
Inhibition of a tumour-associated protease
F. Steven, M. Griffin, H. Maier
19881 citations
Semantic Scholar
Evidence for inhibitors of the cell-surface protease guanidinobenzoatase
F. Steven, M. Griffin, T. L. H. Wong, B. S. Brown +1 more
19861 citations
Semantic Scholar
Inhibition of thrombin cleavage of fibrinogen by polyestradiol phosphate; interaction with the crucial arginine residues in fibrinogen required for enzymic cleavage.
Frank S. Steven, M. Griffin
1982International Journal of Biochemistry1 citations
Semantic Scholar
Inhibition kinetics of a trypsin-like neutral proteinase on the surface of Ehrlich ascites-tumour cells.
Frank S. Steven, M. Griffin, S. Itzhaki
1981Biochemical Society Transactions1 citations
Semantic Scholar
A comparison of the inhibition kinetics of trypsin in free solution and trypsin coupled to Sepharose-4B.
Frank S. Steven, M. Griffin
1981Biochemical Society Transactions1 citations
Semantic Scholar

Frequent co-authors

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Frank S. Steven — researcher profile on SciRah
F. Steven×11
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S. Itzhaki×7
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T. L. H. Wong×6
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H. Maier — researcher profile on SciRah

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I. Talbot — researcher profile on SciRah

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W. Mangel — researcher profile on SciRah

R. K. Al-Ahmad×3

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A. Al-Habib — researcher profile on SciRah

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H. Ali — researcher profile on SciRah

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B. S. Brown — researcher profile on SciRah