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M. Morelli · SciRah

Researcher profile · Semantic Scholar

M. Morelli

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M. Morelli — researcher profile on SciRah

h-index: 17
Works: 76
Citations: 1,313

Most-cited papers

Survival improvement for patients with metastatic colorectal cancer over twenty years
Fadl A Zeineddine, M. Zeineddine, A. Yousef, Yue Gu +18 more
2023npj Precision Oncology197 citations Open access
Semantic Scholar
PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response.
Hsin-Wei Liao, Jung-Mao Hsu, W. Xia, Hung-Ling Wang +18 more
2015Journal of Clinical Investigation137 citations Open access
Semantic Scholar
Tremelimumab in combination with microwave ablation in patients with refractory biliary tract cancer
C. Xie, A. Duffy, Donna Mabry-Hrones, B. Wood +20 more
2019Hepatology92 citations Open access
Semantic Scholar
Therapeutic Silencing of KRAS using Systemically Delivered siRNAs
C. Pecot, S. Wu, S. Bellister, J. Filant +17 more
2014Molecular Cancer Therapeutics90 citations Open access
Semantic Scholar
Prioritizing phase I treatment options through preclinical testing on personalized tumorgraft.
M. Morelli, E. Calvo, E. Ordóñez, M. J. Wick +6 more
2012Journal of Clinical Oncology89 citations Open access
Semantic Scholar
Association of blood biomarkers and autoimmunity with immune related adverse events in patients with cancer treated with immune checkpoint inhibitors
Despina Michailidou, A. Khaki, M. Morelli, L. Diamantopoulos +2 more
2021Scientific Reports85 citations Open access
Semantic Scholar
Synergistic Antitumor Activity of Sorafenib in Combination with Epidermal Growth Factor Receptor Inhibitors in Colorectal and Lung Cancer Cells
Erika Martinelli, T. Troiani, F. Morgillo, G. Rodolico +11 more
2010Clinical Cancer Research83 citations
Semantic Scholar
Identification of Predictive Markers of Response to the MEK1/2 Inhibitor Selumetinib (AZD6244) in K-ras–Mutated Colorectal Cancer
J. Tentler, S. Nallapareddy, A. Tan, A. Spreafico +10 more
2010Molecular Cancer Therapeutics82 citations Open access
Semantic Scholar
Modeling of Patient Derived Xenografts in Colorectal Cancer
A. Katsiampoura, K. Raghav, Zhi-Qin Jiang, D. Menter +15 more
2017Molecular Cancer Therapeutics51 citations Open access
Semantic Scholar
Preclinical Activity of the Rational Combination of Selumetinib (AZD6244) in Combination with Vorinostat in KRAS-Mutant Colorectal Cancer Models
M. Morelli, J. Tentler, G. Kulikowski, A. Tan +9 more
2011Clinical Cancer Research43 citations Open access
Semantic Scholar
A pilot study of the PD-1 targeting agent AMP-224 combined with low-dose cyclophosphamide and stereotactic body radiation therapy in patients with metastatic colorectal cancer
C. Floudas, G. Brar, Donna Mabry-Hrones, A. Duffy +12 more
2019Clinical colorectal cancer42 citations Open access
Semantic Scholar
Targeting vascular endothelial growth factor receptor-1 and -3 with cediranib (AZD2171): effects on migration and invasion of gastrointestinal cancer cell lines
M. Morelli, Amy Brown, T. Pitts, J. Tentler +4 more
2009Molecular Cancer Therapeutics42 citations Open access
Semantic Scholar
Combined immune checkpoint inhibition (ICI) with tremelimumab and durvalumab in patients with advanced hepatocellular carcinoma (HCC) or biliary tract carcinomas (BTC).
C. Floudas, C. Xie, G. Brar, M. Morelli +7 more
2019Journal of Clinical Oncology34 citations
Semantic Scholar
Hurdles and complexities of codon 13 KRAS mutations.
M. Morelli, S. Kopetz
2012Journal of Clinical Oncology28 citations
Semantic Scholar
Clinical utility of circulating cell-free DNA in advanced colorectal cancer
A. L. Lima Pereira, M. Morelli, M. Overman, B. Kee +13 more
2017PLoS ONE26 citations Open access
Semantic Scholar
Antiangiogenic drugs in non-small cell lung cancer treatment
T. Cascone, T. Troiani, M. Morelli, C. Gridelli +1 more
2006Current Opinion in Oncology21 citations
Semantic Scholar
First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors
Christopher B Cole, M. Morelli, Massimo Fantini, M. Miettinen +19 more
2023Journal of experimental & clinical cancer research : CR17 citations Open access
Semantic Scholar
Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination
Kristen Simmons, Jane V. Thomas, K. Ludford, J. Willis +16 more
2023Cancer Research Communications13 citations Open access
Semantic Scholar
Hepatocellular carcinoma (HCC) survival by etiology: A SEER-Medicare database analysis.
G. Brar, T. McNeel, K. McGlynn, B. Graubard +5 more
2019Journal of Clinical Oncology12 citations
Semantic Scholar
Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer
K. Zeligs, M. Morelli, J. David, Monica K. Neuman +13 more
2020Frontiers in Oncology11 citations Open access
Semantic Scholar
The Monoclonal Antibody NEO-201 Enhances Natural Killer Cell Cytotoxicity Against Tumor Cells Through Blockade of the Inhibitory CEACAM5/CEACAM1 Immune Checkpoint Pathway
M. Fantini, J. David, C. Annunziata, M. Morelli +2 more
2020Cancer Biotherapy and Radiopharmaceuticals10 citations Open access
Semantic Scholar
Antitumor activity of nab-paclitaxel and gemcitabine in resectable pancreatic cancer.
R. Álvarez-Gallego, A. Cubillo, J. Rodriguez-Pascual, Y. Quijano +7 more
20129 citations
Semantic Scholar
Safety and efficacy of Sleeping Beauty TCR-T cells targeting shared KRAS and TP53 mutations expressed by solid tumors in first-in-human phase 1 study.
M. Morelli, M. Negrao, M. Collinson-Pautz, Kamisha Jernigan +12 more
2023Journal of Clinical Oncology8 citations Open access
Semantic Scholar
Association of positive ctDNA-based minimal residual disease assays during surveillance and undiagnosed concomitant radiographic recurrences in colorectal cancer (CRC): Results from the MD Anderson INTERCEPT program.
A. Dasari, Alisha H. Bent, Kristin D. Alfaro-Munoz, R. Huey +16 more
2023Journal of Clinical Oncology8 citations
Semantic Scholar
Identification of the O-Glycan Epitope Targeted by the Anti-Human Carcinoma Monoclonal Antibody (mAb) NEO-201
K. Tsang, M. Fantini, Anjum Zaki, Sharon A. Mavroukakis +3 more
2022Cancers7 citations Open access
Semantic Scholar
Frequency of concurrent gene mutations and copy number alterations in circulating cell-free DNA (cfDNA) from refractory metastatic CRC patients.
M. Morelli, M. Overman, E. Sanchez, V. Morris +16 more
20147 citations
Semantic Scholar
INTERCEPT Program of circulating tumor DNA (ctDNA) testing for minimal residual disease (MRD) in colorectal cancer (CRC): Results from a prospective clinical cohort.
G. Maddalena, A. Pellatt, M. Eluri, C. Parseghian +16 more
2024Journal of Clinical Oncology6 citations
Semantic Scholar
Abstract C084: iExplore: A phase I study of mesenchymal stem cell derived exosomes with KrasG12D siRNA for metastatic pancreas cancer patients harboring the KrasG12D mutation
B. Smaglo, V. LeBleu, J. J. Lee, A. Maitra +21 more
2024Cancer Research6 citations
Semantic Scholar
A phase 1/2a, multicenter, open-label study of CNA3103 (LGR5-targeted, autologous CAR-T cells) in patients with metastatic colorectal cancer (mCRC).
Jayesh Desai, J. Iglesias, L. Jablonskis, S. McColl +2 more
2023Journal of Clinical Oncology6 citations Open access
Semantic Scholar
A phase I/II study of pexa-vec oncolytic virus in combination with immune checkpoint inhibition in refractory colorectal cancer: Safety report.
M. Morelli, C. Xie, G. Brar, C. Floudas +4 more
2019Journal of Clinical Oncology6 citations
Semantic Scholar
263 A2B694, an autologous logic-gated cell therapy targeting mesothelin
Julian R. Molina, T. Tokatlian, Jason Wang, Shruti Sharma +22 more
2022Regular and Young Investigator Award Abstracts5 citations Open access
Semantic Scholar
Single-Cell Molecular Characterization to Partition the Human Glioblastoma Tumor Microenvironment Genetic Background
F. Lessi, S. Franceschi, M. Morelli, M. Menicagli +7 more
2022bioRxiv5 citations Open access
Semantic Scholar
Combination of epidermal growth factor receptor inhibitors and antiangiogenic drugs: a model for treatment
E. Martinelli, T. Troiani, F. Morgillo, M. Piccirillo +4 more
2006Targeted oncology5 citations
Semantic Scholar
Epidermal growth factor receptor inhibitors in non-small-cell lung cancer
T. Cascone, E. Martinelli, M. Morelli, F. Morgillo +2 more
2007Expert Opinion on Drug Discovery4 citations
Semantic Scholar
Immune checkpoint inhibition (ICI) in combination with SBRT in patients with advanced pancreatic adenocarcinoma (aPDAC).
G. Brar, C. Xie, C. Floudas, M. Morelli +5 more
2019Journal of Clinical Oncology3 citations
Semantic Scholar
Rationale, discovery and clinical development of NEO-201
P. Arlen, M. Morelli
2019Expert Opinion on Biological Therapy3 citations Open access
Semantic Scholar
Impact of microsatellite instability (MSI) on tumor clonal evolution in metastatic colorectal cancer (mCRC).
J. Willis, M. Morelli, V. Morris, J. Loree +14 more
20183 citations
Semantic Scholar
Redefining the prognostic significance of RAS and BRAF V600E mutations on disease free survival in patients with colorectal cancer in the era of ct-DNA defined minimal residual disease: Results from the MD Anderson INTERCEPT Program.
A. Pellatt, G. Maddalena, M. Eluri, C. Parseghian +16 more
2024Journal of Clinical Oncology2 citations
Semantic Scholar
Correction: First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors
Christopher B Cole, M. Morelli, Massimo Fantini, M. Miettinen +19 more
2023Journal of experimental & clinical cancer research : CR2 citations Open access
Semantic Scholar
Next-Generation Approaches to Immuno-Oncology in GI Cancers.
J. Hecht, J. Mitchell, M. Morelli, G. Anandappa +1 more
2023American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting2 citations Open access
Semantic Scholar
637 Phase IIa combining NEO-201 with pembrolizumab in adults with chemo-resistant solid tumors
Princess Mark-Adjeli, C. Annunziata, Christopher B Cole, M. Morelli +6 more
2022Regular and Young Investigator Award Abstracts2 citations Open access
Semantic Scholar
Phase I with expansion cohorts in a study of NEO-201 in adults with chemo-resistant solid tumors.
M. Morelli, Nicole Houston, S. Lipkowitz, Jung-Min Lee +10 more
20192 citations
Semantic Scholar
Inhibitor Selumetinib (AZD6244) in KRAS-Mutated Colorectal Cancer
J. Tentler, S. Nallapareddy, A. Tan, A. Spreafico +8 more
20102 citations
Semantic Scholar
Natural history and patterns of progression for dMMR/MSI-H colorectal cancer treated with immune checkpoint blockade: A single center retrospective analysis.
V. Higbie, P. Shah, Alisha H. Bent, A. Dasari +14 more
2024Journal of Clinical Oncology1 citations Open access
Semantic Scholar
Improving ethnic and racial diversity in biomarker-driven clinical trials: A proof of concept with the BASECAMP-1 master prescreening study of patients with high-risk solid tumors with human leukocyte antigen-A*02 (HLA-A*02) loss of heterozygosity (LOH).
C. Smith, Diane M. Simeone, Patrick M Grierson, K. Kirtane +15 more
2024Journal of Clinical Oncology1 citations
Semantic Scholar
Abstract CT118: A phase I/II trial of a CXCR1/2 inhibitor in combination with anti-PD-1 for circulating tumor DNA (ctDNA) positive & refractoryRAS-mutated microsatellite stable (MSS) colorectal cancer
Benny Johnson, C. Haymaker, V. Morris, A. Dasari +13 more
2023Cancer Research1 citations
Semantic Scholar
229 A2B530, an autologous CEA-directed Tmod T-cell therapy with an inhibitory receptor gated by HLA-A*02 to target colorectal, pancreatic, and lung cancer
J. Hecht, Mark L. Sandberg, Xueyin Wang, Aaron D. Martin +31 more
2022Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
779TiP Commencement of first-in-human phase I/II TCR-T clinical trial targeting shared tumor-specific hotspot mutations in solid tumors
M. Morelli, M. Negrao, A. Jazaeri, B. Johnson +6 more
2022Annals of Oncology1 citations Open access
Semantic Scholar
P14.01.B Isolation and characterization of circulating tumor cells in a glioblastoma case with recurrence at distance and correlation with tumor mutational status
F. Lessi, M. Morelli, P. Aretini, M. Menicagli +6 more
2022Neuro-Oncology1 citations Open access
Semantic Scholar
Correlation of clinical activity of NEO201 mAb with the expression of NK activation markers and levels of soluble factors.
M. Morelli, M. Fantini, Nicole Houston, Jung-Min Lee +6 more
20201 citations
Semantic Scholar

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