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S. Marciniak · SciRah

Researcher profile · Semantic Scholar

S. Marciniak

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S. Marciniak — researcher profile on SciRah

h-index: 45
Works: 159
Citations: 11K

Most-cited papers

Pharmacological targeting of endoplasmic reticulum stress in disease
S. Marciniak, Joseph E. Chambers, D. Ron
2021Nature reviews. Drug discovery457 citations Open access
Semantic Scholar
Endoplasmic reticulum stress in malignancy.
H. J. Clarke, Joseph E. Chambers, E. Liniker, S. Marciniak
2014Cancer Cell452 citations Open access
Semantic Scholar
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
P. van Galen, Antonija Krešo, Nathan Mbong, D. Kent +12 more
2014Nature355 citations Open access
Semantic Scholar
COVID-19 and pneumothorax: a multicentre retrospective case series
A. Martinelli, T. Ingle, Joseph Newman, I. Nadeem +35 more
2020European Respiratory Journal296 citations Open access
Semantic Scholar
An Optical Technique for Mapping Microviscosity Dynamics in Cellular Organelles.
Joseph E. Chambers, Markéta Kubánková, R. G. Huber, Ismael López-Duarte +4 more
2018ACS Nano140 citations Open access
Semantic Scholar
α1-Antitrypsin deficiency
C. Greene, S. Marciniak, J. Teckman, I. Ferrarotti +4 more
2016Nature Reviews Disease Primers104 citations Open access
Semantic Scholar
PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz
Ana Crespillo-Casado, Joseph E. Chambers, P. Fischer, S. Marciniak +1 more
2017eLife98 citations Open access
Semantic Scholar
Single particle trajectories reveal active Endoplasmic Reticulum luminal flow
D. Holcman, P. Parutto, Joseph E. Chambers, Marcus J. Fantham +5 more
2018Nature Cell Biology95 citations Open access
Semantic Scholar
Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells
Emily F. A. van 't Wout, A. V. van Schadewijk, R. van Boxtel, L. E. Dalton +4 more
2015PLoS Pathogens92 citations Open access
Semantic Scholar
Ambulatory management of primary spontaneous pneumothorax: an open-label, randomised controlled trial
R. Hallifax, E. Mckeown, P. Sivakumar, I. Fairbairn +22 more
2020The Lancet91 citations Open access
Semantic Scholar
Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 2. Protein misfolding and ER stress.
Joseph E. Chambers, S. Marciniak
2014American Journal of Physiology - Cell Physiology81 citations
Semantic Scholar
Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation
Joseph E. Chambers, L. E. Dalton, H. J. Clarke, Elke Malzer +5 more
2015eLife77 citations Open access
Semantic Scholar
G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases
Ru-Ming Chen, C. Rato, Ya-Hui Yan, Ana Crespillo-Casado +5 more
2015eLife77 citations Open access
Semantic Scholar
Endoplasmic reticulum stress in lung disease
S. Marciniak
2017European Respiratory Review72 citations Open access
Semantic Scholar
The Genetics of Pneumothorax.
Philip M. Boone, Rachel M. Scott, S. Marciniak, E. Henske +1 more
2019American Journal of Respiratory and Critical Care Medicine69 citations Open access
Semantic Scholar
Circulating polymers in &agr;1-antitrypsin deficiency
L. Tan, Jennifer A. Dickens, D. DeMeo, E. Miranda +19 more
2014European Respiratory Journal60 citations Open access
Semantic Scholar
hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency
Charis-Patricia Segeritz, S. T. Rashid, M. C. de Brito, M. Serra +13 more
2018Journal of Hepatology58 citations Open access
Semantic Scholar
Palliative treatment for symptomatic malignant pericardial effusion†.
Guled M. Jama, M. Scarci, J. Bowden, S. Marciniak
2014Interactive Cardiovascular and Thoracic Surgery57 citations Open access
Semantic Scholar
Role of unfolded proteins in lung disease
Kirsty L. Bradley, C. A. Stokes, S. Marciniak, L. Parker +1 more
2020Thorax51 citations Open access
Semantic Scholar
Development of a small molecule that corrects misfolding and increases secretion of Z α1‐antitrypsin
D. Lomas, J. Irving, C. Arico-Muendel, S. Belyanskaya +33 more
2020bioRxiv48 citations Open access
Semantic Scholar
HaloFlippers: A General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living Cells
K. Straková, J. López-Andarias, Noemi Jiménez-Rojo, Joseph E. Chambers +4 more
2020ACS Central Science47 citations Open access
Semantic Scholar
Proteostasis During Cerebral Ischemia
Audrey M. Thiebaut, Elodie Hedou, S. Marciniak, D. Vivien +1 more
2019Frontiers in Neuroscience45 citations Open access
Semantic Scholar
A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity
Adriana Ordóñez, Juan Pérez, L. Tan, Jennifer A. Dickens +7 more
2015The FASEB Journal45 citations Open access
Semantic Scholar
The integrated stress response in lung disease.
Emily F. A. van 't Wout, P. Hiemstra, S. Marciniak
2014American Journal of Respiratory Cell and Molecular Biology44 citations Open access
Semantic Scholar
The TRiC/CCT Chaperone Is Implicated in Alzheimer's Disease Based on Patient GWAS and an RNAi Screen in Aβ-Expressing Caenorhabditis elegans
E. Khabirova, Aileen M. Moloney, S. Marciniak, Julie Williams +5 more
2014PLoS ONE42 citations Open access
Semantic Scholar
Polymers of Z α1-antitrypsin are secreted in cell models of disease
A. Fra, F. Cosmi, Adriana Ordóñez, Romina Berardelli +6 more
2016European Respiratory Journal41 citations Open access
Semantic Scholar
The integrated stress response in pulmonary disease
G. Emanuelli, Nikou Nassehzadeh-Tabriz, N. Morrell, S. Marciniak
2020European Respiratory Review35 citations Open access
Semantic Scholar
Z-α1-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state
Joseph E. Chambers, N. Zubkov, Markéta Kubánková, Jonathon Nixon-Abell +14 more
2022Science Advances33 citations Open access
Semantic Scholar
Familial pneumothorax: towards precision medicine
Rachel M. Scott, E. Henske, B. Raby, Philip M. Boone +2 more
2017Thorax33 citations Open access
Semantic Scholar
Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system
L. Ulbrich, F. Favaloro, Laura Trobiani, V. Marchetti +5 more
2015Biochemical Journal33 citations Open access
Semantic Scholar
MesobanK UK: an international mesothelioma bioresource
R. Rintoul, D. Rassl, J. Gittins, S. Marciniak
2015Thorax30 citations Open access
Semantic Scholar
Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers
Adriana Ordóñez, H. Harding, S. Marciniak, D. Ron
2020bioRxiv29 citations Open access
Semantic Scholar
Interactions between N‐linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum
C. Moriconi, Adriana Ordóñez, G. Lupo, B. Gooptu +10 more
2015The FEBS Journal29 citations Open access
Semantic Scholar
Use of preclinical models for malignant pleural mesothelioma
M. Shamseddin, J. Obacz, M. Garnett, R. Rintoul +2 more
2021Thorax28 citations Open access
Semantic Scholar
The integrated stress response regulates BMP signalling through effects on translation
Elke Malzer, Caia S. Dominicus, Joseph E. Chambers, Jennifer A. Dickens +2 more
2018BMC Biology28 citations Open access
Semantic Scholar
COVID-19 pneumothorax in the UK: a prospective observational study using the ISARIC WHO clinical characterisation protocol
S. Marciniak, J. Farrell, A. Rostron, I. Smith +4 more
2021European Respiratory Journal26 citations Open access
Semantic Scholar
Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant
Jennifer A. Dickens, Eimear N. Rutherford, Susana Abreu, Joseph E. Chambers +4 more
2021European Respiratory Journal25 citations Open access
Semantic Scholar
Characterising the association of latency with α1-antitrypsin polymerisation using a novel monoclonal antibody
L. Tan, Juan Pérez, M. Mela, E. Miranda +12 more
2015International Journal of Biochemistry and Cell Biology25 citations Open access
Semantic Scholar
The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α1-antitrypsin
Jennifer A. Dickens, Adriana Ordóñez, Joseph E. Chambers, A. Beckett +8 more
2016The FASEB Journal24 citations Open access
Semantic Scholar
New Concepts in Alpha-1 Antitrypsin Deficiency Disease Mechanisms.
S. Marciniak, Adriana Ordóñez, Jennifer A. Dickens, Joseph E. Chambers +3 more
2016Annals of the American Thoracic Society24 citations Open access
Semantic Scholar
A systematic review assessing the existence of pneumothorax-only variants of FLCN. Implications for lifelong surveillance of renal tumours
K. Matsumoto, D. Lim, P. Pharoah, E. Maher +1 more
2021European Journal of Human Genetics22 citations Open access
Semantic Scholar
Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report)
Irene Dell'anno, E. Barone, L. Mutti, D. Rassl +4 more
2020Journal of Translational Medicine22 citations Open access
Semantic Scholar
Ambulatory Thoracoscopic Pleurodesis Combined With Indwelling Pleural Catheter in Malignant Pleural Effusion
C. Foo, T. Pulimood, M. Knolle, S. Marciniak +1 more
2021Frontiers in Surgery20 citations Open access
Semantic Scholar
Biological basis for novel mesothelioma therapies
J. Obacz, H. Yung, M. Shamseddin, E. Linnane +7 more
2021British Journal of Cancer20 citations Open access
Semantic Scholar
The SARS-CoV-2 viral load in COVID-19 patients is lower on face mask filters than on nasopharyngeal swabs
A. Smolinska, D. Jessop, K. Pappan, Alexandra De Saedeleer +29 more
2021Scientific Reports18 citations Open access
Semantic Scholar
Noninterventional statistical comparison of BTS and CHEST guidelines for size and severity in primary pneumothorax
Marko Nikolic, L. Lok, K. Mattishent, S. Barth +14 more
2015European Respiratory Journal16 citations Open access
Semantic Scholar
Function of monocytes and monocyte-derived macrophages in α1-antitrypsin deficiency
E. F. A. van'T Wout, A. V. van Schadewijk, D. Lomas, J. Stolk +2 more
2014European Respiratory Journal16 citations Open access
Semantic Scholar
BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification
S. E. Barnett, Jenna Kenyani, Martina Tripari, Z. Butt +12 more
2023Molecular Cancer Research15 citations Open access
Semantic Scholar
Large scale clinical trials: lessons from the COVID-19 pandemic
A. Horsley, L. Pearmain, S. Knight, N. Schindler +13 more
2022BMJ Open Respiratory Research15 citations Open access
Semantic Scholar
Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma
J. Obacz, J. Valer, Reshma Nibhani, T. Adams +15 more
2022European Respiratory Journal15 citations Open access
Semantic Scholar

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Joseph E. Chambers — researcher profile on SciRah
D. Lomas×11
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Adriana Ordóñez×10
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E. Miranda — researcher profile on SciRah

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