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Jennifer A. Dickens · SciRah

Researcher profile · Semantic Scholar

Jennifer A. Dickens

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Jennifer A. Dickens — researcher profile on SciRah

h-index: 15
Works: 36
Citations: 925

Most-cited papers

Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease
A. Duvoix, Jennifer A. Dickens, I. Haq, D. Mannino +3 more
2012Thorax225 citations Open access
Semantic Scholar
COPD association and repeatability of blood biomarkers in the ECLIPSE cohort
Jennifer A. Dickens, B. Miller, L. Edwards, E. Silverman +2 more
2011Respiratory Research179 citations Open access
Semantic Scholar
The molecular and cellular pathology of α₁-antitrypsin deficiency.
B. Gooptu, Jennifer A. Dickens, D. Lomas
2014Trends in Molecular Medicine90 citations
Semantic Scholar
Circulating polymers in &agr;1-antitrypsin deficiency
L. Tan, Jennifer A. Dickens, D. DeMeo, E. Miranda +19 more
2014European Respiratory Journal60 citations Open access
Semantic Scholar
A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity
Adriana Ordóñez, Juan Pérez, L. Tan, Jennifer A. Dickens +7 more
2015The FASEB Journal45 citations Open access
Semantic Scholar
Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α1-antitrypsin
Emily F. A. van 't Wout, Jennifer A. Dickens, A. V. van Schadewijk, I. Haq +7 more
2013Human Molecular Genetics42 citations Open access
Semantic Scholar
Z-α1-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state
Joseph E. Chambers, N. Zubkov, Markéta Kubánková, Jonathon Nixon-Abell +14 more
2022Science Advances33 citations Open access
Semantic Scholar
The integrated stress response regulates BMP signalling through effects on translation
Elke Malzer, Caia S. Dominicus, Joseph E. Chambers, Jennifer A. Dickens +2 more
2018BMC Biology28 citations Open access
Semantic Scholar
Altered native stability is the dominant basis for susceptibility of α1-antitrypsin mutants to polymerization
J. Irving, I. Haq, Jennifer A. Dickens, S. V. Faull +1 more
2014Biochemical Journal28 citations Open access
Semantic Scholar
Pulmonary endoplasmic reticulum stress—scars, smoke, and suffocation
Jennifer A. Dickens, Elke Malzer, Joseph E. Chambers, Stefan J. Marciniak
2019The FEBS Journal27 citations Open access
Semantic Scholar
Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant
Jennifer A. Dickens, Eimear N. Rutherford, Susana Abreu, Joseph E. Chambers +4 more
2021European Respiratory Journal25 citations Open access
Semantic Scholar
Characterising the association of latency with α1-antitrypsin polymerisation using a novel monoclonal antibody
L. Tan, Juan Pérez, M. Mela, E. Miranda +12 more
2015International Journal of Biochemistry and Cell Biology25 citations Open access
Semantic Scholar
Reactive centre loop mutants of α-1-antitrypsin reveal position-specific effects on intermediate formation along the polymerization pathway
I. Haq, J. Irving, S. V. Faull, Jennifer A. Dickens +4 more
2013Bioscience Reports25 citations Open access
Semantic Scholar
The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α1-antitrypsin
Jennifer A. Dickens, Adriana Ordóñez, Joseph E. Chambers, A. Beckett +8 more
2016The FASEB Journal24 citations Open access
Semantic Scholar
New Concepts in Alpha-1 Antitrypsin Deficiency Disease Mechanisms.
S. Marciniak, Adriana Ordóñez, Jennifer A. Dickens, Joseph E. Chambers +3 more
2016Annals of the American Thoracic Society24 citations Open access
Semantic Scholar
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
Kyungtae Lim, Eimear N. Rutherford, Dawei Sun, D. V. D. van den Boomen +8 more
2023bioRxiv13 citations Open access
Semantic Scholar
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
Kyungtae Lim, Eimear N. Rutherford, L. Delpiano, Peng He +14 more
2025EMBO Journal12 citations Open access
Semantic Scholar
CC-16 as a Biomarker in Chronic Obstructive Pulmonary Disease
Jennifer A. Dickens, D. Lomas
2012COPD8 citations Open access
Semantic Scholar
Brief Report: A Novel Sodium/Iodide Symporter Mutation, S356F, Causing Congenital Hypothyroidism
H. Durgia, A. Nicholas, E. Schoenmakers, Jennifer A. Dickens +4 more
2021Thyroid5 citations Open access
Semantic Scholar
Measuring the effects of α1‐antitrypsin polymerisation on the structure and biophysical properties of the endoplasmic reticulum
Joseph E. Chambers, Jennifer A. Dickens, S. Marciniak
2018Biology of the Cell2 citations
Semantic Scholar
S64 Circulating polymers are found in alpha-1-antitrypsin deficiency and are associated with lung disease
Jennifer A. Dickens, L. Tan, D. L. Demeo, E. Miranda +19 more
2013Thorax2 citations Open access
Semantic Scholar
T6 Understanding the cellular dysfunction caused by pathogenic surfactant protein c mutant i73t
Jennifer A. Dickens, M. Ellis, Stefan J. Marciniak
2017Thorax1 citations Open access
Semantic Scholar
Gene editing of alveolar organoids reveals AT2 dysfunction due to endosomal SFTPC accumulation.
Eimear N. Rutherford, Dawei Sun, Kyungtae Lim, Christopher S. Godbehere +5 more
2026American Journal of Respiratory Cell and Molecular Biology0 citations Open access
Semantic Scholar
TeloNet is born: why all specialities need to be aware of telomere biology disorders
H. Longhurst, Jane K. Paxton, Hemanth Tummala, D. Baird +8 more
2026Frontiers in Medicine0 citations Open access
Semantic Scholar
Endogenous gene editing of alveolar organoids reveals that expression of pathogenic variant SFTPC-I73T disrupts endosomal function, epithelial polarity and wound healing
Eimear N. Rutherford, Dawei Sun, Kyungtae Lim, James R. Edgar +4 more
2025bioRxiv0 citations Open access
Semantic Scholar
Both terminal misfolding and polymerisation contribute to disease-relevant responses in cell models of α1-antitrypsin deficiency-associated liver disease
P. Stylianou, Kish R. Adoni, M. Nyon, A. Cryar +14 more
2025bioRxiv0 citations Open access
Semantic Scholar
Thyroid Cancer: Symptoms, Causes, Diagnosis and its Treatment
Jennifer A. Dickens
20210 citations
Semantic Scholar
Subcellular Responses To Misfolding In Er Stress And alpha 1-Antitrypsin Deficiency
B. Gooptu, M. Nyon, A. Cryar, Charis-Patricia Segeritz +7 more
20150 citations
Semantic Scholar
S126 Measuring ER protein mobility during ER fragmentation in alpha-1-antitrypsin deficiency
Jennifer A. Dickens, A. Ordóñez, Joseph E. Chambers, David A. Lomas +1 more
20150 citations Open access
Semantic Scholar
Native stability and the pathway of alpha 1-antitrypsin polymerisation
J. Irving, I. Haq, Jennifer A. Dickens, S. V. Faull +1 more
20140 citations
Semantic Scholar
Summary of the literature assessing a relationship between fibrinogen and chronic obstructive pulmonary disease ( COPD )
A. Duvoix, Jennifer A. Dickens, I. Haq, D. Mannino +3 more
20130 citations
Semantic Scholar
expressing Z α1-antitrypsin
Jennifer A. Dickens, A. V. van Schadewijk, I. Haq, Adriana Ordóñez +5 more
20130 citations
Semantic Scholar
Defining The Mechanism Of Polymerisation That Underlies α1-Antitrypsin Deficiency
Jennifer A. Dickens, I. Haq, Adriana Ordóñez, D. Belorgey +2 more
2012Asian Test Symposium0 citations
Semantic Scholar
The role of interferon-γ release assay (IGRA) testing in a UK teaching hospital
M. Mason, Jennifer A. Dickens, D. Aguilar, G. Hardingham +1 more
2011European Respiratory Journal0 citations
Semantic Scholar
Phi Alpha Theta Initiates
C. Brazell, Agnes Scott, M. R. Beyer, K. Clark +109 more
20100 citations
Semantic Scholar
Both terminal misfolding and polymerisation contribute to disease-relevant phenotypic changes in cell models of α 1 -antitrypsin deficiency-associated liver disease
P. Stylianou, Kish R. Adoni, M. Nyon, A. Cryar +15 more
0 citations
Semantic Scholar

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