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Ralph R. Reid · SciRah

Researcher profile · Semantic Scholar

Ralph R. Reid

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Ralph R. Reid — researcher profile on SciRah

h-index: 26
Works: 43
Citations: 4,199

Most-cited papers

A new enzyme superfamily - the phosphopantetheinyl transferases.
R. H. Lambalot, A. M. Gehring, R. Flugel, P. Zuber +5 more
1996Chemistry and Biology765 citations Open access
Semantic Scholar
Long-term stabilization of maleimide-thiol conjugates.
Shaun D. Fontaine, Ralph R. Reid, Louise H. Robinson, G. Ashley +1 more
2015Bioconjugate chemistry381 citations
Semantic Scholar
Hydrogel drug delivery system with predictable and tunable drug release and degradation rates
G. Ashley, Jeff Henise, Ralph R. Reid, D. Santi
2013Proceedings of the National Academy of Sciences of the United States of America338 citations Open access
Semantic Scholar
Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes
Hugo G Menzella, Ralph R. Reid, J. Carney, S. Chandran +4 more
2005Nature Biotechnology328 citations
Semantic Scholar
A model of structure and catalysis for ketoreductase domains in modular polyketide synthases.
Ralph R. Reid, Misty Piagentini, E. Rodriguez, G. Ashley +5 more
2003Biochemistry286 citations
Semantic Scholar
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.
Sarah J Kodumal, Kedar G. Patel, Ralph R. Reid, Hugo G Menzella +2 more
2004Proceedings of the National Academy of Sciences of the United States of America235 citations Open access
Semantic Scholar
Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides.
A. Schirmer, J. Kennedy, S. Murli, Ralph R. Reid +1 more
2006Proceedings of the National Academy of Sciences of the United States of America160 citations
Semantic Scholar
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.
A. Rascher, Zhi-Hao Hu, N. Viswanathan, A. Schirmer +4 more
2003FEMS Microbiology Letters141 citations Open access
Semantic Scholar
Evolution in action.
T. Scanlan, Ralph R. Reid
1995Chemistry and Biology137 citations Open access
Semantic Scholar
Identification of new RNA modifying enzymes by iterative genome search using known modifying enzymes as probes.
Claes M. Gustafsson, Ralph R. Reid, Patricia J. Greene, D. Santi
1996Nucleic Acids Research134 citations Open access
Semantic Scholar
Exposition of a family of RNA m(5)C methyltransferases from searching genomic and proteomic sequences.
Ralph R. Reid, Patricia J. Greene, D. Santi
1999Nucleic Acids Research128 citations Open access
Semantic Scholar
Genes for the Biosynthesis of the Fungal Polyketides Hypothemycin from Hypomyces subiculosus and Radicicol from Pochonia chlamydosporia
C. Reeves, Zhi-Hao Hu, Ralph R. Reid, J. Kealey
2008Applied and Environmental Microbiology122 citations Open access
Semantic Scholar
Predictable and tunable half-life extension of therapeutic agents by controlled chemical release from macromolecular conjugates
D. Santi, Eric L Schneider, Ralph R. Reid, Louise H. Robinson +1 more
2012Proceedings of the National Academy of Sciences of the United States of America104 citations Open access
Semantic Scholar
Analysis of the ambruticin and jerangolid gene clusters of Sorangium cellulosum reveals unusual mechanisms of polyketide biosynthesis.
Bryan Julien, Zong-Qiang Tian, Ralph R. Reid, C. Reeves
2006Chemistry and Biology104 citations Open access
Semantic Scholar
Insights into the Biosynthesis of the Benzoquinone Ansamycins Geldanamycin and Herbimycin, Obtained by Gene Sequencing and Disruption
A. Rascher, Zhi-Hao Hu, Greg O. Buchanan, Ralph R. Reid +1 more
2005Applied and Environmental Microbiology96 citations Open access
Semantic Scholar
GeMS: an advanced software package for designing synthetic genes
Sebastian Jayaraj, Ralph R. Reid, D. Santi
2005Nucleic Acids Research82 citations Open access
Semantic Scholar
Elucidating the mechanism of cis double bond formation in epothilone biosynthesis.
Li Tang, Shannon L. Ward, L. Chung, J. Carney +3 more
2004Journal of the American Chemical Society73 citations
Semantic Scholar
Action mechanism of Escherichia coli DNA photolyase. I. Formation of the enzyme-substrate complex.
G. B. Sancar, F. Smith, Ralph R. Reid, G. Payne +2 more
1987Journal of Biological Chemistry68 citations Open access
Semantic Scholar
The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation.
R. Carvalho, Ralph R. Reid, N. Viswanathan, H. Gramajo +1 more
2005Gene66 citations
Semantic Scholar
Chalcomycin Biosynthesis Gene Cluster from Streptomyces bikiniensis: Novel Features of an Unusual Ketolide Produced through Expression of the chm Polyketide Synthase in Streptomyces fradiae
Shannon L. Ward, Zhi-Hao Hu, A. Schirmer, Ralph R. Reid +5 more
2004Antimicrobial Agents and Chemotherapy65 citations Open access
Semantic Scholar
Molecular modeling and crystal structure of ERK2-hypothemycin complexes.
G. Rastelli, R. Rosenfeld, Ralph R. Reid, D. Santi
2008Journal of Structural Biology49 citations Open access
Semantic Scholar
Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster
Hugo G Menzella, Sarah J. Reisinger, M. Welch, J. Kealey +4 more
2005Journal of Industrial Microbiology & Biotechnology49 citations Open access
Semantic Scholar
Hydrogel Drug Delivery System Using Self-Cleaving Covalent Linkers for Once-a-Week Administration of Exenatide.
Eric L Schneider, Jeff Henise, Ralph R. Reid, G. Ashley +1 more
2016Bioconjugate chemistry43 citations
Semantic Scholar
A very long-acting IL-15: implications for the immunotherapy of cancer
John A. Hangasky, Wei Chen, S. Dubois, Anusara Daenthanasanmak +4 more
2022Journal for ImmunoTherapy of Cancer39 citations Open access
Semantic Scholar
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System
Ralph R. Reid, M. Sgobba, Barak Raveh, G. Rastelli +2 more
201531 citations Open access
Semantic Scholar
A Hydrogel-Microsphere Drug Delivery System That Supports Once-Monthly Administration of a GLP-1 Receptor Agonist.
Eric L Schneider, B. R. Hearn, S. Pfaff, Ralph R. Reid +4 more
2017ACS Chemical Biology28 citations
Semantic Scholar
PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89
D. Beckford-Vera, Shaun D. Fontaine, H. VanBrocklin, B. R. Hearn +3 more
2019Molecular Cancer Therapeutics24 citations Open access
Semantic Scholar
Species-specific optimization of PEG~SN-38 prodrug pharmacokinetics and antitumor effects in a triple-negative BRCA1-deficient xenograft
Shaun D. Fontaine, B. Hann, Ralph R. Reid, G. Ashley +1 more
2019Cancer Chemotherapy and Pharmacology20 citations
Semantic Scholar
Approach for Half-Life Extension of Small Antibody Fragments That Does Not Affect Tissue Uptake.
Eric L Schneider, B. R. Hearn, S. Pfaff, Shaun D. Fontaine +7 more
2016Bioconjugate chemistry19 citations Open access
Semantic Scholar
Subcutaneously Administered Self-Cleaving Hydrogel-Octreotide Conjugates Provide Very Long-Acting Octreotide.
Eric L Schneider, Jeff Henise, Ralph R. Reid, G. Ashley +1 more
2016Bioconjugate chemistry19 citations
Semantic Scholar
A once-monthly GLP-1 receptor agonist for treatment of diabetic cats.
Eric L Schneider, Ralph R. Reid, D. Parkes, T. Lutz +2 more
2019Domestic Animal Endocrinology18 citations Open access
Semantic Scholar
A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules
Nobuo Machinaga, G. Ashley, Ralph R. Reid, Atsushi Yamasaki +5 more
2018Translational Vision Science & Technology18 citations Open access
Semantic Scholar
β-Eliminative releasable linkers adapted for bioconjugation of macromolecules to phenols.
Eric L Schneider, Louise H. Robinson, Ralph R. Reid, G. Ashley +1 more
2013Bioconjugate chemistry13 citations
Semantic Scholar
A long-acting C-natriuretic peptide for achondroplasia
Eric L Schneider, C. Carreras, Ralph R. Reid, G. Ashley +1 more
2022Proceedings of the National Academy of Sciences of the United States of America11 citations Open access
Semantic Scholar
A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors
Shaun D. Fontaine, C. Carreras, Ralph R. Reid, G. Ashley +1 more
2023Cancer Research Communications7 citations Open access
Semantic Scholar
PLX038: a PEGylated prodrug of SN-38 independent of UGT1A1 activity
Shaun D. Fontaine, A. D. Santi, Ralph R. Reid, Philip C. Smith +2 more
2019Cancer Chemotherapy and Pharmacology5 citations
Semantic Scholar
Functional expression of the dihydrofolate reductase domain of Leishmania major dihydrofolate reductase-thymidylate synthase bifunctional protein.
Pak-Lam Yu, Jia Zhao, Ming Yu, Ralph R. Reid +1 more
1996Protein Expression and Purification3 citations
Semantic Scholar
Development of a long acting c-natriuretic peptide suitable for QMo dosing
Eric L. Schneider, Christopher W. Carreras, Ralph R. Reid, Gary W. Ashley +1 more
2024Development of a long acting c-natriuretic peptide suitable for QMo dosing0 citations Open access
Semantic Scholar
Long-Acting Poly(ADP-ribose) Polymerase Inhibitor Prodrug for Humans.
Christopher W. Carreras, Shaun D. Fontaine, Ralph R. Reid, Gary W. Ashley +1 more
2024Bioconjugate chemistry0 citations
Semantic Scholar
Inhibiteurs de kinases specifiques
D. Santi, Ralph R. Reid, Richard C. Hutchinson, Kurt F. Sundermann +1 more
20050 citations
Semantic Scholar
Polynucleotides codant la synthase de polycetide disorazole
Bryan Julien, Ralph R. Reid
20030 citations
Semantic Scholar
Phosphopantethenyltransferasen and their uses
R. H. Lambalot, A. M. Gehring, Ralph R. Reid, C. Walsh
19960 citations
Semantic Scholar
Transferases de phosphopantetheinyles et leurs utilisations
A. M. Gehring, R. H. Lambalot, Ralph R. Reid, Christopher Walsh
19960 citations
Semantic Scholar

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Eric L Schneider×8
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Shaun D. Fontaine×7
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Hugo G Menzella×3

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