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Laura M. Hoffman · SciRah

Researcher profile · Semantic Scholar

Laura M. Hoffman

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Laura M. Hoffman — researcher profile on SciRah

h-index: 17
Works: 19
Citations: 1,784

Most-cited papers

Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement
M. Yoshigi, Laura M. Hoffman, Christopher C. Jensen, H. Yost +1 more
2005Journal of Cell Biology428 citations Open access
Semantic Scholar
Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling
Laura M. Hoffman, Christopher C. Jensen, S. Kloeker, C. Wang +2 more
2006Journal of Cell Biology179 citations Open access
Semantic Scholar
Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth
S. Sankar, E. Theisen, Jared J. Bearss, Timothy S. Mulvihill +5 more
2014Clinical Cancer Research153 citations Open access
Semantic Scholar
From the membrane to the nucleus and back again: bifunctional focal adhesion proteins.
M. Hervy, Laura M. Hoffman, M. Beckerle
2006Current Opinion in Cell Biology140 citations
Semantic Scholar
Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators
Laura M. Hoffman, Christopher C. Jensen, Aashi Chaturvedi, M. Yoshigi +1 more
2012Molecular Biology of the Cell130 citations Open access
Semantic Scholar
Targeted Disruption of the Murine zyxin Gene
Laura M. Hoffman, David A. Nix, Beverly A. Benson, R. Boot-Hanford +9 more
2003Molecular and Cellular Biology105 citations Open access
Semantic Scholar
The EWS/FLI Oncogene Drives Changes in Cellular Morphology, Adhesion, and Migration in Ewing Sarcoma.
Aashi Chaturvedi, Laura M. Hoffman, A. Welm, S. Lessnick +1 more
2012Genes & cancer104 citations Open access
Semantic Scholar
Mechanical signals activate p38 MAPK pathway-dependent reinforcement of actin via mechanosensitive HspB1
Laura M. Hoffman, Christopher C. Jensen, M. Yoshigi, M. Beckerle
2017Molecular Biology of the Cell85 citations Open access
Semantic Scholar
LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain
Mark A. Smith, E. Blankman, Nicholas O. Deakin, Laura M. Hoffman +3 more
2013PLoS ONE85 citations Open access
Semantic Scholar
Mechanical stress triggers nuclear remodeling and the formation of transmembrane actin nuclear lines with associated nuclear pore complexes
Laura M. Hoffman, Mark A. Smith, Christopher C. Jensen, M. Yoshigi +3 more
2020Molecular Biology of the Cell74 citations Open access
Semantic Scholar
Supervillin modulation of focal adhesions involving TRIP6/ZRP-1
N. Takizawa, Tara C. Smith, T. Nebl, J. Crowley +6 more
2006Journal of Cell Biology73 citations Open access
Semantic Scholar
Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma
Aashi Chaturvedi, Laura M. Hoffman, Christopher C. Jensen, Yi-Chun Lin +5 more
2014Molecular Biology of the Cell61 citations Open access
Semantic Scholar
EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma
John Fadul, R. Bell, Laura M. Hoffman, M. Beckerle +2 more
2015Genes & cancer42 citations Open access
Semantic Scholar
The LIM Protein Zyxin Binds CARP-1 and Promotes Apoptosis
M. Hervy, Laura M. Hoffman, Christopher C. Jensen, Mark A. Smith +1 more
2010Genes & cancer37 citations Open access
Semantic Scholar
Regulatory features of multicatalytic and 26S proteases.
Laura M. Hoffman, M. Rechsteiner
1996Current Topics in Cellular Regulation28 citations
Semantic Scholar
Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility
Laura M. Hoffman, Christopher C. Jensen, M. Beckerle
2022Molecular Biology of the Cell27 citations Open access
Semantic Scholar
Nuclear pore complexes concentrate on Actin/LINC/Lamin nuclear lines in response to mechanical stress in a SUN1 dependent manner
Mark A. Smith, E. Blankman, Christopher C. Jensen, Laura M. Hoffman +2 more
2022Heliyon17 citations Open access
Semantic Scholar
Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility
Stephen R. Piccolo, Laura M. Hoffman, Thomas A. Conner, G. Shrestha +11 more
2016Molecular Systems Biology12 citations Open access
Semantic Scholar
Cancer Therapy : Preclinical Reversible LSD 1 Inhibition Interferes with Global EWS / ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth
S. Sankar, E. Theisen, Jared J. Bearss, Timothy S. Mulvihill +5 more
20144 citations
Semantic Scholar

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