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I. Sominskaya · SciRah

Researcher profile · Semantic Scholar

I. Sominskaya

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I. Sominskaya — researcher profile on SciRah

h-index: 18
Works: 43
Citations: 979

Most-cited papers

Nuclear Entry of Hepatitis B Virus Capsids Involves Disintegration to Protein Dimers followed by Nuclear Reassociation to Capsids
B. Rabe, Mildred Delaleau, A. Bischof, Michael Foss +5 more
2009PLoS Pathogens104 citations Open access
Semantic Scholar
Construction and Immunological Evaluation of Multivalent Hepatitis B Virus (HBV) Core Virus-Like Particles Carrying HBV and HCV Epitopes
I. Sominskaya, D. Skrastina, A. Dišlers, D. Vasiljev +4 more
2010Clinical and Vaccine Immunology86 citations Open access
Semantic Scholar
Priming of cytotoxic T cell responses to exogenous hepatitis B virus core antigen is B cell dependent.
Una Lazdina, M. Alheim, Jessica Nyström, C. Hultgren +6 more
2003Journal of General Virology85 citations Open access
Semantic Scholar
HCV Core Protein Uses Multiple Mechanisms to Induce Oxidative Stress in Human Hepatoma Huh7 Cells
A. Ivanov, O. Smirnova, I. Petrushanko, O. Ivanova +7 more
2015Viruses76 citations Open access
Semantic Scholar
N-terminal myristoylation-dependent masking of neutralizing epitopes in the preS1 attachment site of hepatitis B virus.
C. Bremer, I. Sominskaya, D. Skrastina, P. Pumpens +7 more
2011Journal of Hepatology62 citations Open access
Semantic Scholar
An outbreak of HBV and HCV infection in a paediatric oncology ward: Epidemiological investigations and prevention of further spread
U. Dumpis, Zanna Kovaļova, J. Jansons, L. Čupāne +8 more
2003Journal of Medical Virology58 citations
Semantic Scholar
Recombinant virus-like particles as a carrier of B- and T-cell epitopes of hepatitis C virus (HCV).
M. Mihailova, Mechthild Boos, I. Petrovskis, V. Ose +7 more
2006Vaccine48 citations
Semantic Scholar
A VLP Library of C-Terminally Truncated Hepatitis B Core Proteins: Correlation of RNA Encapsidation with a Th1/Th2 Switch in the Immune Responses of Mice
I. Sominskaya, D. Skrastina, I. Petrovskis, Andris Dishlers +8 more
2013PLoS ONE41 citations Open access
Semantic Scholar
Evaluation of HBs, HBc, and frCP Virus-Like Particles for Expression of Human Papillomavirus 16 E7 Oncoprotein Epitopes
P. Pumpens, R. Ražanskas, P. Pushko, R. Renhof +8 more
2002Intervirology41 citations
Semantic Scholar
Analysis of RNA phage fr coat protein assembly by insertion, deletion and substitution mutagenesis.
Peter Pushko, T. Kozlovskaya, I. Sominskaya, A. Brede +4 more
1993Protein Engineering40 citations
Semantic Scholar
The chaperone dynein LL1 mediates cytoplasmic transport of empty and mature hepatitis B virus capsids.
Quentin Osseman, Lara Gallucci, Shelly Au, C. Cazenave +12 more
2017Journal of Hepatology34 citations Open access
Semantic Scholar
Determination of the minimal length of preS1 epitope recognized by a monoclonal antibody which inhibits attachment of Hepatitis B virus to hepatocytes
I. Sominskaya, Peter Pushko, D. Dreilina, T. Kozlovskaya +1 more
2004Medical Microbiology and Immmunology34 citations
Semantic Scholar
Fine mapping and functional characterization of two immuno-dominant regions from the preS2 sequence of hepatitis B virus.
H. Meisel, I. Sominskaya, Pauls Pumpēns, Peter Pushko +7 more
1994Intervirology31 citations
Semantic Scholar
High immunogenicity of a hydrophilic component of the hepatitis B virus preS1 sequence exposed on the surface of three virus-like particle carriers.
D. Skrastina, A. Bulavaitė, I. Sominskaya, L. Kovalevska +4 more
2008Vaccine29 citations
Semantic Scholar
Mosaic hepatitis B virus core particles presenting the complete preS sequence of the viral envelope on their surface.
A. Kazaks, G. Borisova, Svetlana Cvetkova, L. Kovalevska +5 more
2004Journal of General Virology21 citations Open access
Semantic Scholar
Production of the HBc Protein from Different HBV Genotypes in E. coli. Use of Reassociated HBc VLPs for Packaging of ss- and dsRNA
I. Petrovskis, I. Liekniņa, A. Dišlers, J. Jansons +4 more
2021Microorganisms19 citations Open access
Semantic Scholar
The Hepatitis B Virus Core Variants that Expose Foreign C-Terminal Insertions on the Outer Surface of Virus-Like Particles
Andris Dishlers, D. Skrastina, Regīna Renhofa, I. Petrovskis +5 more
2015Molecular Biotechnology19 citations Open access
Semantic Scholar
Tetrapeptide QDPR is a minimal immunodominant epitope within the preS2 domain of hepatitis B virus.
I. Sominskaya, V. Bichko, Peter Pushko, A. Dreĭmane +2 more
1992Immunology Letters18 citations
Semantic Scholar
Genetic adjuvants: A paradigm shift in vaccine development and immune modulation
K. Spunde, K. Korotkaja, I. Sominskaya, A. Zajakina
2025Molecular Therapy: Nucleic Acids17 citations Open access
Semantic Scholar
Preparation of hepatitis C virus structural and non-structural protein fragments and studies of their immunogenicity.
M. Mihailova, M. Fiedler, Mechthild Boos, I. Petrovskis +4 more
2006Protein Expression and Purification17 citations
Semantic Scholar
Signal sequences modulate the immunogenic performance of human hepatitis C virus E2 gene.
I. Sominskaya, Ekaterina Alekseeva, D. Skrastina, V. Mokhonov +8 more
2006Molecular Immunology14 citations
Semantic Scholar
Chimeric Derivatives of Hepatitis B Virus Core Particles Carrying Major Epitopes of the Rubella Virus E1 Glycoprotein
D. Skrastina, I. Petrovskis, R. Petraitytė, I. Sominskaya +5 more
2013Clinical and Vaccine Immunology13 citations Open access
Semantic Scholar
Fine-mapping of the B-cell epitope domain at the N-terminus of the preS2 region of the hepatitis B surface antigen.
I. Sominskaya, W. Paulij, J. Jansons, D. Sobotta +5 more
2002JIM - Journal of Immunological Methods12 citations
Semantic Scholar
PreS1 Containing HBc VLPs for the Development of a Combined Therapeutic/Prophylactic Hepatitis B Vaccine
Andris Dishlers, I. Petrovskis, D. Skrastina, Ieva Zarina +6 more
2023Microorganisms9 citations Open access
Semantic Scholar
Fibronectin-binding nanoparticles for intracellular targeting addressed by B. burgdorferi BBK32 protein fragments.
R. Ranka, I. Petrovskis, I. Sominskaya, J. Bogans +7 more
2013Nanomedicine: Nanotechnology, Biology and Medicine9 citations Open access
Semantic Scholar
Hepatitis B and C Virus Variants in Long-Term Immunosuppressed Renal Transplant Patients in Latvia
I. Sominskaya, M. Mihailova, J. Jansons, V. Emelyanova +5 more
2005Intervirology9 citations
Semantic Scholar
Reciprocal Inhibition of Immunogenic Performance in Mice of Two Potent DNA Immunogens Targeting HCV-Related Liver Cancer
J. Jansons, D. Skrastina, Alisa Kurlanda, S. Petkov +7 more
2021Microorganisms8 citations Open access
Semantic Scholar
The Immunogenicity in Mice of HCV Core Delivered as DNA Is Modulated by Its Capacity to Induce Oxidative Stress and Oxidative Stress Response
J. Jansons, I. Sominskaya, N. Petrakova, E. Starodubova +10 more
2019Cells7 citations Open access
Semantic Scholar
Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen
Ekaterina Alekseeva, I. Sominskaya, D. Skrastina, I. Egorova +8 more
2009Genetic Vaccines and Therapy6 citations Open access
Semantic Scholar
Toward a SARS-CoV-2 VLP Vaccine: HBc/G as a Carrier for SARS-CoV-2 Spike RBM and Nucleocapsid Protein-Derived Peptides
I. Petrovskis, D. Skrastina, J. Jansons, A. Dišlers +6 more
2024Vaccines5 citations Open access
Semantic Scholar
Hepatitis C virus molecular epidemiology in Latvia
J. Jansons, G. Sudmale, I. Sominskaya, P. Pumpens
20043 citations
Semantic Scholar
Comparative Immunogenicity in Rabbits of the Polypeptides Encoded by the 5′ Terminus of Hepatitis C Virus RNA
I. Sominskaya, J. Jansons, A. Dovbenko, N. Petrakova +8 more
2015Journal of Immunological Research2 citations Open access
Semantic Scholar
Chimeric derivatives of Hepatitis B core particles carrying major epitopes of the 4 Rubella virus E 1 glycoprotein 5 6 Running title : Hepatitis B core particles carrying Rubella virus E 1 epitopes
D. Skrastina, I. Petrovskis, R. Petraitytė, I. Sominskaya +5 more
20131 citations
Semantic Scholar
Hepatitis B Virus Genotypes in Latvia
I. Sominskaya, Maria Mihailova, J. Jansons, Diana Legzdina +8 more
20111 citations Open access
Semantic Scholar
Immunological Methods for Analysis of Recombinant Proteins
I. Sominskaya, K. Ta̅rs
19981 citations
Semantic Scholar
Immunogenicity of SARS-CoV-2 vaccine prototype based on virus-like particles of hepatitis B core antigen from genotype G and interleukin 12 expressing Semliki Forest virus as a genetic adjuvant
A. Dišlers, O. Nilova, J. Jansons, D. Skrastina +7 more
2026Journal of General Virology0 citations Open access
Semantic Scholar
The immunogenicity in mice of hepatitis C virus core protein delivered as DNA is modulated by its capacity to promote ROS production and activate Nrf2/ARE pathway
A. Ivanov, J. Jansons, N. Petrakova, E. Starodubova +9 more
2018Free Radical Biology & Medicine0 citations
Semantic Scholar
361 – Hepatitis C Virus Core Protein Triggers ROS Production by Several Distinct Mechanisms
A. Ivanov, O. Smirnova, O. Ivanova, I. Petrushanko +5 more
20140 citations
Semantic Scholar
Hepatitis C Virus Vaccine Candidates from Chimeric Hepatitis B Core Virus-like Particles Carrying Different Fragments of HCV Non-structural Protein 3
M. Mihailova, A. Dovbenko, J. Bogans, A. Walker +4 more
20110 citations
Semantic Scholar
Expression of hepatitis C virus structural genes controlled by alphaviral recombinant replicons
Ekaterina Alekseeva, I. Sominskaya, R. Brūvere, V. Ose +2 more
20080 citations
Semantic Scholar
Is vaccine against HCV possible
M. Mihailova, I. Sominskaya, S. Viazov, P. Pumpens
20070 citations
Semantic Scholar
Contents, Vol. 37, 1994
H. Meisel, I. Sominskaya, P. Pumpens, P. Pushko +53 more
19940 citations Open access
Semantic Scholar
Subject Index, Vol. 37, 1994
H. Meisel, I. Sominskaya, P. Pumpens, P. Pushko +53 more
19940 citations Open access
Semantic Scholar

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