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K. Tsuchihara · SciRah

Researcher profile · Semantic Scholar

K. Tsuchihara

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K. Tsuchihara — researcher profile on SciRah

h-index: 47
Works: 245
Citations: 8,585

Most-cited papers

Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies
Yoshiaki Nakamura, H. Taniguchi, M. Ikeda, H. Bando +35 more
2020Nature Medicine330 citations
Semantic Scholar
Panitumumab vs Bevacizumab Added to Standard First-line Chemotherapy and Overall Survival Among Patients With RAS Wild-type, Left-Sided Metastatic Colorectal Cancer: A Randomized Clinical Trial.
J. Watanabe, K. Muro, K. Shitara, K. Yamazaki +24 more
2023Journal of the American Medical Association (JAMA)256 citations Open access
Semantic Scholar
Baseline ctDNA gene alterations as a biomarker of survival after panitumumab and chemotherapy in metastatic colorectal cancer
K. Shitara, K. Muro, J. Watanabe, K. Yamazaki +27 more
2024Nature Medicine118 citations Open access
Semantic Scholar
Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1)
Y. Naito, H. Aburatani, T. Amano, E. Baba +29 more
2020International Journal of Clinical Oncology107 citations Open access
Semantic Scholar
Single-cell analyses reveal diverse mechanisms of resistance to EGFR tyrosine kinase inhibitors in lung cancer
Y. Kashima, D. Shibahara, A. Suzuki, Kyoko Muto +13 more
2021Cancer Research65 citations Open access
Semantic Scholar
Spatially resolved gene expression profiling of tumor microenvironment reveals key steps of lung adenocarcinoma development
Y. Takano, Jun Suzuki, Kotaro Nomura, G. Fujii +18 more
2024Nature Communications57 citations Open access
Semantic Scholar
SCRUM‐Japan GI‐SCREEN and MONSTAR‐SCREEN: Path to the realization of biomarker‐guided precision oncology in advanced solid tumors
Yoshiaki Nakamura, T. Fujisawa, H. Taniguchi, H. Bando +4 more
2021Cancer Science57 citations Open access
Semantic Scholar
International Harmonization of Provisional Diagnostic Criteria for ERBB2-Amplified Metastatic Colorectal Cancer Allowing for Screening by Next-Generation Sequencing Panel.
S. Fujii, A. Magliocco, Jihun Kim, W. Okamoto +9 more
2020JCO Precision Oncology48 citations Open access
Semantic Scholar
Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations
S. Ikemura, H. Yasuda, S. Matsumoto, M. Kamada +24 more
2019Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Comprehensive single-cell analysis demonstrates radiotherapy-induced infiltration of macrophages expressing immunosuppressive genes into tumor in esophageal squamous cell carcinoma
H. Oyoshi, Jun-Yan Du, Shunsuke A. Sakai, Riu Yamashita +18 more
2023Science Advances41 citations Open access
Semantic Scholar
Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast
Satoi Nagasawa, Y. Kuze, I. Maeda, Yasuyuki Kojima +15 more
2020medRxiv40 citations Open access
Semantic Scholar
The initial assessment of expert panel performance in core hospitals for cancer genomic medicine in Japan
K. Sunami, Y. Naito, Eriko Aimono, T. Amano +11 more
2021International Journal of Clinical Oncology39 citations Open access
Semantic Scholar
Long-read sequencing for non-small-cell lung cancer genomes
Yoshitaka Sakamoto, Liu Xu, M. Seki, Toshiyuki T. Yokoyama +11 more
2020Genome Research38 citations Open access
Semantic Scholar
Chronological improvement in precision oncology implementation in Japan
K. Komine, K. Sunami, Y. Naito, T. Amano +14 more
2021Cancer Science37 citations Open access
Semantic Scholar
Deleterious Pulmonary Surfactant System Gene Mutations in Lung Adenocarcinomas Associated With Usual Interstitial Pneumonia.
T. Honda, H. Sakashita, K. Masai, Hirohiko Totsuka +15 more
2018JCO Precision Oncology36 citations
Semantic Scholar
Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer
K. Ishioka, H. Yasuda, Junko Hamamoto, H. Terai +31 more
2021Cancer Research33 citations Open access
Semantic Scholar
The impact of tertiary lymphoid structures on clinicopathological, genetic and gene expression characteristics in lung adenocarcinoma.
Y. Tamiya, T. Nakai, A. Suzuki, S. Mimaki +19 more
2022Lung Cancer31 citations Open access
Semantic Scholar
Japan Society of Clinical Oncology provisional clinical opinion for the diagnosis and use of immunotherapy in patients with deficient DNA mismatch repair tumors, cooperated by Japanese Society of Medical Oncology, First Edition
S. Mishima, H. Taniguchi, K. Akagi, E. Baba +12 more
2019International Journal of Clinical Oncology29 citations Open access
Semantic Scholar
Transposable elements potentiate radiotherapy-induced cellular immune reactions via RIG-I-mediated virus-sensing pathways
Jun-Yan Du, S. Kageyama, Riu Yamashita, Kosuke Tanaka +16 more
2023Communications Biology26 citations Open access
Semantic Scholar
Comparative analysis of the immune responses in cancer cells irradiated with X-ray, proton and carbon-ion beams.
Jun-Yan Du, S. Kageyama, H. Hirata, A. Motegi +8 more
2021Biochemical and Biophysical Research Communications - BBRC26 citations Open access
Semantic Scholar
Negative hyperselection of patients with RAS wild-type metastatic colorectal cancer for panitumumab: A biomarker study of the phase III PARADIGM trial.
K. Shitara, K. Muro, J. Watanabe, K. Yamazaki +16 more
2023Journal of Clinical Oncology25 citations
Semantic Scholar
PARP inhibitor olaparib sensitizes esophageal carcinoma cells to fractionated proton irradiation
S. Kageyama, Jun-Yan Du, H. Hojo, A. Motegi +3 more
2020Journal of Radiation Research24 citations Open access
Semantic Scholar
Comparative sequence analysis of patient-matched primary colorectal cancer, metastatic, and recurrent metastatic tumors after adjuvant FOLFOX chemotherapy
K. Harada, W. Okamoto, S. Mimaki, Y. Kawamoto +8 more
2019BMC Cancer24 citations Open access
Semantic Scholar
Potentiality of multiple modalities for single-cell analyses to evaluate the tumor microenvironment in clinical specimens
Y. Kashima, Yosuke Togashi, S. Fukuoka, Takahiro Kamada +19 more
2021Scientific Reports23 citations Open access
Semantic Scholar
Appropriate use of cancer comprehensive genome profiling assay using circulating tumor DNA
K. Sunami, H. Bando, Y. Yatabe, Y. Naito +13 more
2021Cancer Science20 citations Open access
Semantic Scholar
Genetic profiling-based prognostic prediction of patients with advanced small-cell lung cancer in large scale analysis.
H. Udagawa, S. Umemura, I. Murakami, S. Mimaki +9 more
2018Lung Cancer20 citations
Semantic Scholar
Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan
Y. Naito, K. Sunami, H. Kage, K. Komine +21 more
2022JAMA Network Open18 citations Open access
Semantic Scholar
Amino BODIPY-Based Blue Fluorescent Probes for Aldehyde Dehydrogenase 1-Expressing Cells.
Atsushi Yagishita, Tasuku Ueno, K. Tsuchihara, Y. Urano
2021Bioconjugate chemistry17 citations
Semantic Scholar
A Learning Program for Treatment Recommendations by Molecular Tumor Boards and Artificial Intelligence
K. Sunami, Yoichi Naito, Y. Saigusa, T. Amano +31 more
2023JAMA Oncology16 citations Open access
Semantic Scholar
Impacts of the STING‐IFNAR1‐STAT1‐IRF1 pathway on the cellular immune reaction induced by fractionated irradiation
Jun-Yan Du, S. Kageyama, Riu Yamashita, H. Hirata +15 more
2022Cancer Science16 citations Open access
Semantic Scholar
Single-cell spatial analysis with Xenium reveals anti-tumour responses of CXCL13 + T and CXCL9+ cells after radiotherapy combined with anti-PD-L1 therapy
Shunsuke A. Sakai, H. Oyoshi, M. Nakamura, T. Taki +20 more
2025British Journal of Cancer14 citations Open access
Semantic Scholar
Patient survey on cancer genomic medicine in Japan under the national health insurance system
H. Kage, Nana Akiyama, Hyangri Chang, A. Shinozaki-Ushiku +19 more
2024Cancer Science14 citations Open access
Semantic Scholar
Effects of ado-trastuzumab emtansine and fam-trastuzumab deruxtecan on metastatic breast cancer harboring HER2 amplification and the L755S mutation.
T. Mukohara, A. Hosono, S. Mimaki, Akiko Nakayama +10 more
2021The Oncologist14 citations Open access
Semantic Scholar
Multifocal origin of occupational cholangiocarcinoma revealed by comparison of multilesion mutational profiles.
S. Mimaki, Masahiko Watanabe, M. Kinoshita, Riu Yamashita +11 more
2020Carcinogenesis13 citations
Semantic Scholar
Histopathological factors affecting the extraction of high quality genomic DNA from tissue sections for next-generation sequencing.
S. Fujii, T. Yoshino, K. Yamazaki, K. Muro +21 more
2019Biomedical Reports13 citations Open access
Semantic Scholar
Characterization of cancer omics and drug perturbations in panels of lung cancer cells
A. Suzuki, Keiichi Onodera, Ken Matsui, M. Seki +6 more
2019Scientific Reports13 citations Open access
Semantic Scholar
Human resources for administrative work to carry out a comprehensive genomic profiling test in Japan
H. Kage, K. Oda, M. Muto, K. Tsuchihara +16 more
2023Cancer Science12 citations Open access
Semantic Scholar
Clinicopathological, gene expression and genetic features of stage I lung adenocarcinoma with necrosis.
Hiroaki Oiwa, K. Aokage, A. Suzuki, Kei Sato +11 more
2021Lung Cancer12 citations
Semantic Scholar
Efficacy of Targeted Trials and Signaling Pathway Landscape in Advanced Gastrointestinal Cancers From SCRUM-Japan GI-SCREEN: A Nationwide Genomic Profiling Program
Yoshiaki Nakamura, Riu Yamashita, W. Okamoto, Y. Komatsu +32 more
2023JCO Precision Oncology11 citations Open access
Semantic Scholar
Expert panel consensus recommendations on the use of circulating tumor DNA assays for patients with advanced solid tumors
Mitsuho Imai, Yoshiaki Nakamura, K. Sunami, H. Kage +17 more
2022Cancer Science11 citations Open access
Semantic Scholar
Fecal microbiota in patients with a stoma decreases anaerobic bacteria and alters taxonomic and functional diversities
Shunsuke Sakai, M. Aoshima, K. Sawada, S. Horasawa +17 more
2022Frontiers in Cellular and Infection Microbiology11 citations Open access
Semantic Scholar
Metabolic Hallmarks for Purine Nucleotide Biosynthesis in Small Cell Lung Carcinoma
S. Tabata, S. Umemura, Miyu Narita, H. Udagawa +9 more
2023Molecular Cancer Research10 citations Open access
Semantic Scholar
Identification of the mutation signature of the cancer genome caused by irradiation.
S. Kageyama, Jun-Yan Du, Syuzo Kaneko, Ryuji Hamamoto +8 more
2020Radiotherapy and Oncology10 citations Open access
Semantic Scholar
Long read sequencing reveals a novel class of structural aberrations in cancers: identification and characterization of cancerous local amplifications
Yoshitaka Sakamoto, Liu Xu, M. Seki, Toshiyuki T. Yokoyama +11 more
2019bioRxiv10 citations Open access
Semantic Scholar
Clinical significance of a prospective large genomic screening for small-cell lung cancer: the genetic classification and a biomarker driven phase II trial of gedatolisib.
S. Umemura, H. Udagawa, T. Ikeda, Haruyasu Murakami +30 more
2024Journal of Thoracic Oncology9 citations Open access
Semantic Scholar
Mathematical Modeling Predicts Optimal Immune Checkpoint Inhibitor and Radiotherapy Combinations and Timing of Administration
Shunsuke A. Sakai, Koichi Saeki, Sunggi Chi, Yamato Hamaya +14 more
2024Cancer immunology research8 citations Open access
Semantic Scholar
Japanese Society of Medical Oncology/Japan Society of Clinical Oncology/Japanese Society of Pediatric Hematology/Oncology-led clinical recommendations on the diagnosis and use of tropomyosin receptor kinase inhibitors in adult and pediatric patients with neurotrophic receptor tyrosine kinase fusion-
Y. Naito, S. Mishima, K. Akagi, N. Hayashi +28 more
2023International Journal of Clinical Oncology8 citations Open access
Semantic Scholar
Association between the mutational smoking signature and the immune microenvironment in lung adenocarcinoma.
Kei Sato, S. Mimaki, Riu Yamashita, Yosuke Togashi +16 more
2020Lung Cancer8 citations
Semantic Scholar
Nivolumab for treating patients with occupational cholangiocarcinoma
Shogo Tanaka, K. Umemoto, S. Kubo, Yasunori Sato +6 more
2022Journal of hepato-biliary-pancreatic sciences7 citations
Semantic Scholar
Microbiome Landscape and Association with Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors: A SCRUM-Japan MONSTAR-SCREEN Study
K. Sawada, Riu Yamashita, Shunsuke A. Sakai, S. Horasawa +28 more
2025Cancer Research Communications6 citations Open access
Semantic Scholar

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K. Komine — researcher profile on SciRah

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