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Ryuji Hamamoto · SciRah

Researcher profile · Semantic Scholar

Ryuji Hamamoto

National Cancer Center Japan

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Ryuji Hamamoto — researcher profile on SciRah

ORCID iD 0000-0002-2632-1334Homepage

h-index: 51
Works: 174
Citations: 9,347

Most-cited papers

Development of a real-time endoscopic image diagnosis support system using deep learning technology in colonoscopy
M. Yamada, Yutaka Saito, Hitoshi Imaoka, Masahiro Saiko +8 more
2019Scientific Reports249 citations Open access
Semantic Scholar
The Development of a Skin Cancer Classification System for Pigmented Skin Lesions Using Deep Learning
S. Jinnai, N. Yamazaki, Y. Hirano, Yohei Sugawara +2 more
2020Biomolecules244 citations Open access
Semantic Scholar
Application of Artificial Intelligence Technology in Oncology: Towards the Establishment of Precision Medicine
Ryuji Hamamoto, K. Suvarna, Masayoshi Yamada, Kazuma Kobayashi +16 more
2020Cancers156 citations Open access
Semantic Scholar
Detection of Cardiac Structural Abnormalities in Fetal Ultrasound Videos Using Deep Learning
M. Komatsu, Akira Sakai, R. Komatsu, R. Matsuoka +10 more
2021Applied Sciences133 citations Open access
Semantic Scholar
Human gut-microbiome-derived propionate coordinates proteasomal degradation via HECTD2 upregulation to target EHMT2 in colorectal cancer
T. Ryu, Kwangho Kim, Tae-Su Han, Mi-Ok Lee +18 more
2022The ISME Journal112 citations Open access
Semantic Scholar
Epigenetics Analysis and Integrated Analysis of Multiomics Data, Including Epigenetic Data, Using Artificial Intelligence in the Era of Precision Medicine
Ryuji Hamamoto, M. Komatsu, Ken Takasawa, Ken Asada +1 more
2019Biomolecules107 citations Open access
Semantic Scholar
Towards Clinical Application of Artificial Intelligence in Ultrasound Imaging
M. Komatsu, Akira Sakai, A. Dozen, K. Shozu +5 more
2021Biomedicines102 citations Open access
Semantic Scholar
Image Segmentation of the Ventricular Septum in Fetal Cardiac Ultrasound Videos Based on Deep Learning Using Time-Series Information
A. Dozen, M. Komatsu, Akira Sakai, R. Komatsu +10 more
2020Biomolecules81 citations Open access
Semantic Scholar
Predicting Deep Learning Based Multi-Omics Parallel Integration Survival Subtypes in Lung Cancer Using Reverse Phase Protein Array Data
Satoshi Takahashi, Ken Asada, Ken Takasawa, Ryohei Shimoyama +8 more
2020Biomolecules65 citations Open access
Semantic Scholar
Oncogenic histone methyltransferase EZH2: A novel prognostic marker with therapeutic potential in endometrial cancer
Shinya Oki, Kenbun Sone, K. Oda, Ryuji Hamamoto +16 more
2017OncoTarget65 citations Open access
Semantic Scholar
Application of non-negative matrix factorization in oncology: one approach for establishing precision medicine
Ryuji Hamamoto, Ken Takasawa, Hidenori Machino, Kazuma Kobayashi +11 more
2022Briefings Bioinform.64 citations Open access
Semantic Scholar
Medical Professional Enhancement Using Explainable Artificial Intelligence in Fetal Cardiac Ultrasound Screening
Akira Sakai, M. Komatsu, R. Komatsu, R. Matsuoka +9 more
2022Biomedicines52 citations Open access
Semantic Scholar
Uncovering Prognosis-Related Genes and Pathways by Multi-Omics Analysis in Lung Cancer
Ken Asada, Kazuma Kobayashi, Samuel Joutard, Masashi Tubaki +6 more
2020Biomolecules51 citations Open access
Semantic Scholar
Introducing AI to the molecular tumor board: one direction toward the establishment of precision medicine using large-scale cancer clinical and biological information
Ryuji Hamamoto, T. Koyama, Nobuji Kouno, T. Yasuda +14 more
2022Experimental Hematology & Oncology49 citations Open access
Semantic Scholar
Genomic alterations in STK11 can predict clinical outcomes in cervical cancer patients.
S. Hirose, N. Murakami, Kazuaki Takahashi, I. Kuno +22 more
2019Gynecologic Oncology48 citations
Semantic Scholar
Observing deep radiomics for the classification of glioma grades
Kazuma Kobayashi, M. Miyake, Masamichi Takahashi, Ryuji Hamamoto
2021Scientific Reports47 citations Open access
Semantic Scholar
Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro
Yusuke Matsuno, Yuko Atsumi, Atsuhiro Shimizu, K. Katayama +11 more
2019Nature Communications46 citations Open access
Semantic Scholar
WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer
V. Saloura, Theodore Vougiouklakis, M. Zewde, Xiaolan Deng +8 more
2017Scientific Reports45 citations Open access
Semantic Scholar
Critical roles of SMYD2-mediated β-catenin methylation for nuclear translocation and activation of Wnt signaling
Xiaolan Deng, Ryuji Hamamoto, T. Vougiouklakis, Rui Wang +6 more
2017OncoTarget43 citations Open access
Semantic Scholar
Integrated Analysis of Whole Genome and Epigenome Data Using Machine Learning Technology: Toward the Establishment of Precision Oncology
Ken Asada, Syuzo Kaneko, Ken Takasawa, Hidenori Machino +5 more
2021Frontiers in Oncology39 citations Open access
Semantic Scholar
Effects of SMYD2‐mediated EML4‐ALK methylation on the signaling pathway and growth in non‐small‐cell lung cancer cells
Rui Wang, Xiaolan Deng, Yuichiro Yoshioka, T. Vougiouklakis +6 more
2017Cancer Science39 citations Open access
Semantic Scholar
Fine-Tuning Approach for Segmentation of Gliomas in Brain Magnetic Resonance Images with a Machine Learning Method to Normalize Image Differences among Facilities
Satoshi Takahashi, Masamichi Takahashi, M. Kinoshita, M. Miyake +24 more
2021Cancers38 citations Open access
Semantic Scholar
Application of Artificial Intelligence for Medical Research
Ryuji Hamamoto
2021Biomolecules37 citations Open access
Semantic Scholar
Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma
Y. Shigekawa, S. Hayami, Masaki Ueno, A. Miyamoto +6 more
2018OncoTarget37 citations Open access
Semantic Scholar
EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression
Jinkwon Lee, Kwangho Kim, T. Ryu, Cho-Rok Jung +7 more
2021Molecular Oncology36 citations Open access
Semantic Scholar
Model-Agnostic Method for Thoracic Wall Segmentation in Fetal Ultrasound Videos
K. Shozu, M. Komatsu, Akira Sakai, R. Komatsu +10 more
2020Biomolecules36 citations Open access
Semantic Scholar
The novel prognostic marker, EHMT2, is involved in cell proliferation via HSPD1 regulation in breast cancer
Seon-Kyu Kim, Kwangho Kim, Jea-Woon Ryu, T. Ryu +8 more
2018International Journal of Oncology36 citations Open access
Semantic Scholar
A Positive Correlation Between the EZH2 and PD-L1 Expression in Resected Lung Adenocarcinomas.
G. Toyokawa, K. Takada, T. Tagawa, Ryuji Hamamoto +4 more
2019Annals of Thoracic Surgery34 citations
Semantic Scholar
Regulation of poly(ADP-Ribose) polymerase 1 functions by post-translational modifications.
Lian-Hua Piao, Kyoko Fujioka, M. Nakakido, Ryuji Hamamoto
2018Frontiers in Bioscience34 citations
Semantic Scholar
Loss of BRCA1 in the cells of origin of ovarian cancer induces glycolysis: A window of opportunity for ovarian cancer chemoprevention
T. Chiyoda, Peter C. Hart, M. Eckert, S. McGregor +7 more
2017Cancer Prevention Research34 citations Open access
Semantic Scholar
Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules
Amina Bolatkan, Ken Asada, Syuzo Kaneko, K. Suvarna +5 more
2021International Journal of Oncology33 citations Open access
Semantic Scholar
TP53 mutants and non-HPV16/18 genotypes are poor prognostic factors for concurrent chemoradiotherapy in locally advanced cervical cancer
I. Kuno, D. Takayanagi, Y. Asami, N. Murakami +12 more
2021Scientific Reports32 citations Open access
Semantic Scholar
Fully-Connected Neural Networks with Reduced Parameterization for Predicting Histological Types of Lung Cancer from Somatic Mutations
Kazuma Kobayashi, Amina Bolatkan, S. Shiina, Ryuji Hamamoto
2020Biomolecules32 citations Open access
Semantic Scholar
Deregulation of the Histone Lysine-Specific Demethylase 1 Is Involved in Human Hepatocellular Carcinoma
Sangchul Kim, Amina Bolatkan, Syuzo Kaneko, Noriko Ikawa +7 more
2019Biomolecules31 citations Open access
Semantic Scholar
Novel prognostic marker PRMT1 regulates cell growth via downregulation of CDKN1A in HCC
Jea-Woon Ryu, Seon-Kyu Kim, M. Son, S. Jeon +7 more
2017OncoTarget31 citations Open access
Semantic Scholar
Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization
Yuichiro Yoshioka, Takehiro Suzuki, Y. Matsuo, G. Tsurita +4 more
2017Cancer Medicine31 citations Open access
Semantic Scholar
Epigenetic regulation of SMAD3 by histone methyltransferase SMYD2 promotes lung cancer metastasis
Kwangho Kim, T. Ryu, E. Jung, Tae-Su Han +12 more
2023Experimental and Molecular Medicine30 citations Open access
Semantic Scholar
Comparative Analysis of Genetic Alterations, HPV-Status, and PD-L1 Expression in Neuroendocrine Carcinomas of the Cervix
D. Takayanagi, S. Hirose, I. Kuno, Y. Asami +12 more
2021Cancers29 citations Open access
Semantic Scholar
Single-Cell Analysis Using Machine Learning Techniques and Its Application to Medical Research
Ken Asada, Ken Takasawa, Hidenori Machino, Satoshi Takahashi +7 more
2021Biomedicines29 citations Open access
Semantic Scholar
Clinical significance of the C-reactive protein-to-albumin ratio for the prognosis of patients with esophageal squamous cell carcinoma.
M. Kunizaki, T. Tominaga, Kouki Wakata, T. Miyazaki +9 more
2017Molecular and clinical oncology29 citations Open access
Semantic Scholar
Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas.
Asako Kukita, Kenbun Sone, K. Oda, Ryuji Hamamoto +17 more
2019Biochemical and Biophysical Research Communications - BBRC28 citations
Semantic Scholar
Shadow Estimation for Ultrasound Images Using Auto-Encoding Structures and Synthetic Shadows
S. Yasutomi, T. Arakaki, R. Matsuoka, Akira Sakai +9 more
2021Applied Sciences26 citations Open access
Semantic Scholar
The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma
Hidenori Machino, Syuzo Kaneko, M. Komatsu, Noriko Ikawa +13 more
2022Communications Biology25 citations Open access
Semantic Scholar
C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation
T. Ozawa, Syuzo Kaneko, Frank Szulzewsky, Zhi-Wei Qiao +6 more
2021Acta Neuropathologica Communications25 citations Open access
Semantic Scholar
Two Secreted Proteoglycans, Activators of Urothelial Cell–Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression
V. Papadaki, Ken Asada, J. Watson, T. Tamura +18 more
2020Cancers25 citations Open access
Semantic Scholar
The histone methyltransferase SMYD2 is a novel therapeutic target for the induction of apoptosis in ovarian clear cell carcinoma cells
Machiko Kojima, Kenbun Sone, K. Oda, Ryuji Hamamoto +16 more
2020Oncology Letters23 citations Open access
Semantic Scholar
Clinical Significance of Serum p53 Antibody in the Early Detection and Poor Prognosis of Gastric Cancer.
M. Kunizaki, A. Fukuda, Kouki Wakata, T. Tominaga +10 more
2017Anticancer Research23 citations Open access
Semantic Scholar
The Epithelial Expressions of YAP and TAZ are Sequentially Required in Lung Development.
Hideaki Isago, A. Mitani, Y. Mikami, Masafumi Horie +4 more
2020American Journal of Respiratory Cell and Molecular Biology22 citations
Semantic Scholar
Clinical Value of Serum p53 Antibody in the Diagnosis and Prognosis of Esophageal Squamous Cell Carcinoma.
M. Kunizaki, K. Hamasaki, Kouki Wakata, Syuichi Tobinaga +10 more
2018Anticancer Research22 citations
Semantic Scholar
Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer
Miku Wada, Asako Kukita, Kenbun Sone, Ryuji Hamamoto +15 more
2020Biomolecules21 citations Open access
Semantic Scholar

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Syuzo Kaneko×23
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M. Komatsu×22
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Ken Asada×18
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Hidenori Machino×13
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Ken Takasawa×8

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Amina Bolatkan×7

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Kazuma Kobayashi×6

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