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Rikke B. Holmgaard · SciRah

Researcher profile · Semantic Scholar

Rikke B. Holmgaard

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Rikke B. Holmgaard — researcher profile on SciRah

h-index: 11
Works: 20
Citations: 2,703

Most-cited papers

Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy
D. Zamarin, Rikke B. Holmgaard, S. Subudhi, J. Park +5 more
2014Science Translational Medicine689 citations Open access
Semantic Scholar
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
Rikke B. Holmgaard, D. Zamarin, D. Munn, J. Wolchok +1 more
2013Journal of Experimental Medicine623 citations Open access
Semantic Scholar
Tumor-expressed IDO recruits and activates MDSCs in a Treg-dependent manner
Rikke B. Holmgaard, D. Zamarin, Yan-Yun Li, Billel Gasmi +4 more
2015Cell Reports456 citations Open access
Semantic Scholar
Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint blockade
Rikke B. Holmgaard, David A. Schaer, Yan-Xia Li, S. Castaneda +13 more
2018Journal of Immunotherapy for Cancer323 citations Open access
Semantic Scholar
The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment
Madhav Sharma, Rahul S. Shinde, T. McGaha, Lei Huang +11 more
2015Science Advances158 citations Open access
Semantic Scholar
Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors
Rikke B. Holmgaard, D. Zamarin, A. Lesokhin, T. Merghoub +1 more
2016EBioMedicine137 citations Open access
Semantic Scholar
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
D. Zamarin, Rikke B. Holmgaard, J. Ricca, T. Plitt +5 more
2017Nature Communications135 citations Open access
Semantic Scholar
Timing of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy
Rikke B. Holmgaard, Alexandra Brachfeld, Billel Gasmi, David R. Jones +6 more
2016Oncoimmunology66 citations Open access
Semantic Scholar
The New Era of Cancer Immunotherapy: Manipulating T-Cell Activity to Overcome Malignancy.
D. Khalil, S. Budhu, Billel Gasmi, R. Zappasodi +8 more
2015Advances in Cancer Research47 citations
Semantic Scholar
The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells
Madhav Sharma, Rahul S. Shinde, T. McGaha, Lei Huang +11 more
2015Journal of Immunotherapy for Cancer23 citations Open access
Semantic Scholar
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +496 more
2016Journal for ImmunoTherapy of Cancer18 citations Open access
Semantic Scholar
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in anti-tumor T cell immunotherapy targeting CTLA-4
Rikke B. Holmgaard, D. Zamarin, D. Munn, J. Wolchok +1 more
2013Journal of Immunotherapy for Cancer9 citations Open access
Semantic Scholar
Association of a functional Indoleamine 2,3-dioxygenase 2 genotype with specific immune responses
T. Køllgaard, T. Klausen, M. Idorn, Rikke B. Holmgaard +2 more
2012Oncoimmunology9 citations Open access
Semantic Scholar
FcγRIIIa-dependent IFN-γ release in whole blood assay is predictive of therapeutic IgG1 antibodies safety
Nada S. Alakhras, Jiabin Qiu, G. Rocha, D. Witcher +7 more
2018mAbs8 citations Open access
Semantic Scholar
Potentiation of immunomodulatory antibodies with oncolytic viruses for therapy of poorly-immunogenic tumors
D. Zamarin, Rikke B. Holmgaard, T. Plitt, J. Allison +2 more
2014Journal of Immunotherapy for Cancer2 citations Open access
Semantic Scholar
Potentiation of immune checkpoint blockade cancer immunotherapy with oncolytic virus.
D. Zamarin, Rikke B. Holmgaard, S. Subudhi, J. Park +5 more
20141 citations
Semantic Scholar
Expression of indoleamine 2.3-dioxygenase by tumors induces local and systemic immunosuppressive effects in a murine melanoma model
Rikke B. Holmgaard, D. Zamarin, D. Munn, T. Merghoub +1 more
2014Journal of Immunotherapy for Cancer1 citations Open access
Semantic Scholar
Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection
D. Zamarin, Rikke B. Holmgaard, S. Subudhi, M. Mansour +4 more
2013Journal of Immunotherapy for Cancer1 citations Open access
Semantic Scholar
Expression of indoleamine 2.3-dioxygenase (IDO) by tumors induces local and systemic immunosuppressive effects in a murine melanoma model (TUM10P.1029)
Rikke B. Holmgaard, D. Zamarin, D. Munn, T. Merghoub +1 more
2015Journal of Immunology0 citations
Semantic Scholar
Indoleamine 2,3-dioxygenase and T-cell based anti-tumor immunotherapies targeting immune checkpoints (P2010)
Rikke B. Holmgaard, D. Zamarin, D. Munn, J. Wolchok +1 more
2013Journal of Immunology0 citations
Semantic Scholar

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J. Wolchok×18
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J. Wolchok — researcher profile on SciRah
D. Zamarin×13
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D. Zamarin — researcher profile on SciRah
T. Merghoub×13
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J. Allison×10
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Billel Gasmi×3

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