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E. Farkas · SciRah

Researcher profile · Semantic Scholar

E. Farkas

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E. Farkas — researcher profile on SciRah

h-index: 47
Works: 134
Citations: 8,553

Most-cited papers

Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases.
E. Farkas, P. Luiten, F. Bari
2007Brain Research Reviews719 citations Open access
Semantic Scholar
Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group
J. Dreier, M. Fabricius, C. Ayata, O. Sakowitz +86 more
2017Journal of Cerebral Blood Flow and Metabolism317 citations Open access
Semantic Scholar
The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão’s legacy
J. Hartings, C. Shuttleworth, Sergei A. Kirov, C. Ayata +30 more
2017Journal of Cerebral Blood Flow and Metabolism316 citations Open access
Semantic Scholar
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
S. Tarantini, M. N. Valcarcel-Ares, Peter Toth, A. Yabluchanskiy +11 more
2019Redox Biology268 citations Open access
Semantic Scholar
Vascular dysfunction in the pathogenesis of Alzheimer's disease--A review of endothelium-mediated mechanisms and ensuing vicious circles.
Luigi Yuri Di Marco, A. Venneri, E. Farkas, P. Evans +2 more
2015Neurobiology of Disease257 citations Open access
Semantic Scholar
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions
E. Császár, N. Lénárt, C. Cserép, Z. Környei +22 more
2022Journal of Experimental Medicine216 citations Open access
Semantic Scholar
Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain
T. Kiss, Ádám Nyúl-Tóth, Priya Balasubramanian, S. Tarantini +9 more
2020GeroScience195 citations Open access
Semantic Scholar
Treatment with the mitochondrial‐targeted antioxidant peptide SS‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice
S. Tarantini, N. Valcarcel‐Ares, A. Yabluchanskiy, G. Fulop +8 more
2018Aging Cell190 citations Open access
Semantic Scholar
Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood–Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype
S. Tarantini, M. N. Valcarcel-Ares, A. Yabluchanskiy, Zsuzsanna Tucsek +12 more
2018The journals of gerontology. Series A, Biological sciences and medical sciences160 citations Open access
Semantic Scholar
Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects
T. Kiss, Ádám Nyúl-Tóth, Priya Balasubramanian, S. Tarantini +8 more
2020GeroScience159 citations Open access
Semantic Scholar
IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging
Peter Toth, S. Tarantini, Nicole M. Ashpole, Zsuzsanna Tucsek +7 more
2015Aging Cell152 citations Open access
Semantic Scholar
Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation
G. Fulop, T. Kiss, S. Tarantini, Priya Balasubramanian +5 more
2018GeroScience150 citations Open access
Semantic Scholar
Pharmacologically-Induced Neurovascular Uncoupling is Associated with Cognitive Impairment in Mice
S. Tarantini, P. Hertelendy, Zsuzsanna Tucsek, M. N. Valcarcel-Ares +10 more
2015Journal of Cerebral Blood Flow and Metabolism146 citations Open access
Semantic Scholar
Resveratrol Preserves Cerebrovascular Density and Cognitive Function in Aging Mice
C. Oomen, E. Farkas, V. Román, E. van der Beek +2 more
2009Front. Ag. Neurosci.131 citations Open access
Semantic Scholar
Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment
T. Kiss, Priya Balasubramanian, M. N. Valcarcel-Ares, S. Tarantini +9 more
2019GeroScience120 citations Open access
Semantic Scholar
Is Vasomotion in Cerebral Arteries Impaired in Alzheimer’s Disease?
L. Di Marco, E. Farkas, Chris J. Martin, A. Venneri +1 more
2015Journal of Alzheimer's Disease101 citations Open access
Semantic Scholar
Tissue Acidosis Associated with Ischemic Stroke to Guide Neuroprotective Drug Delivery
Orsolya M. Tóth, Ákos Menyhárt, Rita Frank, Dóra Hantosi +2 more
2020Biology100 citations Open access
Semantic Scholar
Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects
T. Kiss, C. Giles, S. Tarantini, A. Yabluchanskiy +10 more
2019GeroScience96 citations Open access
Semantic Scholar
Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging
S. Tarantini, A. Yabluchanskiy, Tamás Csípő, G. Fulop +11 more
2019GeroScience94 citations Open access
Semantic Scholar
Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence
Z. Ungvari, S. Tarantini, P. Hertelendy, M. N. Valcarcel-Ares +6 more
2017GeroScience94 citations Open access
Semantic Scholar
Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer’s disease using functional laser speckle contrast imaging
S. Tarantini, G. Fulop, T. Kiss, E. Farkas +6 more
2017GeroScience91 citations Open access
Semantic Scholar
Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment.
G. Fulop, S. Tarantini, A. Yabluchanskiy, A. Molnár +10 more
2019American Journal of Physiology. Heart and Circulatory Physiology87 citations Open access
Semantic Scholar
The Critical Role of Spreading Depolarizations in Early Brain Injury: Consensus and Contention
R. Andrew, J. Hartings, C. Ayata, K. Brennan +12 more
2022Neurocritical Care77 citations Open access
Semantic Scholar
Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice
G. Fulop, Chetan Ahire, Tamás Csípő, S. Tarantini +9 more
2019GeroScience75 citations Open access
Semantic Scholar
Direct, live imaging of cortical spreading depression and anoxic depolarisation using a fluorescent, voltage-sensitive dye
E. Farkas, R. Pratt, F. Sengpiel, T. Obrenovitch
2007Journal of Cerebral Blood Flow and Metabolism69 citations Open access
Semantic Scholar
Imaging Reveals the Focal Area of Spreading Depolarizations and a Variety of Hemodynamic Responses in a Rat Microembolic Stroke Model
Zsófia Bere, T. Obrenovitch, Gábor Kozák, F. Bari +1 more
2014Journal of Cerebral Blood Flow and Metabolism65 citations Open access
Semantic Scholar
N,N-Dimethyltryptamine attenuates spreading depolarization and restrains neurodegeneration by sigma-1 receptor activation in the ischemic rat brain.
Írisz Szabó, V. Varga, S. Dvorácskó, A. Farkas +12 more
2021Neuropharmacology64 citations Open access
Semantic Scholar
Multi-modal imaging of anoxic depolarization and hemodynamic changes induced by cardiac arrest in the rat cerebral cortex
E. Farkas, F. Bari, T. Obrenovitch
2010NeuroImage59 citations
Semantic Scholar
Simultaneous, live imaging of cortical spreading depression and associated cerebral blood flow changes, by combining voltage-sensitive dye and laser speckle contrast methods
T. Obrenovitch, Shangbin Chen, E. Farkas
2009NeuroImage55 citations
Semantic Scholar
Spreading depolarization remarkably exacerbates ischemia-induced tissue acidosis in the young and aged rat brain
Ákos Menyhárt, Dániel Zölei-Szénási, T. Puskás, P. Makra +7 more
2017Scientific Reports54 citations Open access
Semantic Scholar
Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice
S. Tarantini, Andriy Yabluchanksiy, G. Fülöp, P. Hertelendy +8 more
2017GeroScience54 citations Open access
Semantic Scholar
Which Spreading Depolarizations Are Deleterious To Brain Tissue?
C. Shuttleworth, R. D. Andrew, Yama Akbari, C. Ayata +21 more
2019Neurocritical Care46 citations Open access
Semantic Scholar
Ischemia-induced depolarizations and associated hemodynamic responses in incomplete global forebrain ischemia in rats.
Zsófia Bere, T. Obrenovitch, F. Bari, E. Farkas
2014Neuroscience45 citations
Semantic Scholar
Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization
R. Andrew, E. Farkas, J. Hartings, K. Brennan +11 more
2022Neurocritical Care43 citations Open access
Semantic Scholar
What should a clinician do when spreading depolarizations are observed in a patient? Proceedings from the International Conference on Spreading Depolarizations 2018
R. Helbok, J. Hartings, A. Schiefecker, Baptiste Balança +13 more
2019Neurocritical Care41 citations Open access
Semantic Scholar
Effects of cyclooxygenase (COX) inhibition on memory impairment and hippocampal damage in the early period of cerebral hypoperfusion in rats.
A. Institoris, E. Farkas, Sándor Berczi, Z. Sule +1 more
2007European Journal of Pharmacology41 citations
Semantic Scholar
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
S. Tarantini, M. N. Valcarcel-Ares, Peter Toth, A. Yabluchanskiy +7 more
2020The FASEB Journal40 citations Open access
Semantic Scholar
Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci
Ákos Menyhárt, Rita Frank, A. Farkas, Z. Süle +14 more
2020bioRxiv37 citations Open access
Semantic Scholar
Changes in pro-oxidant and antioxidant enzyme levels during cerebral hypoperfusion in rats.
E. Mracsko, M. Hugyecz, A. Institoris, E. Farkas +1 more
2010Brain Research37 citations
Semantic Scholar
Susceptibility of the cerebral cortex to spreading depolarization in neurological disease states: The impact of aging.
P. Hertelendy, D. Varga, Ákos Menyhárt, F. Bari +1 more
2019Neurochemistry International36 citations Open access
Semantic Scholar
High incidence of adverse cerebral blood flow responses to spreading depolarization in the aged ischemic rat brain.
Ákos Menyhárt, P. Makra, Borbála É. Szepes, Orsolya M. Tóth +3 more
2015Neurobiology of Aging36 citations Open access
Semantic Scholar
Role of endothelial NAD+ deficiency in age-related vascular dysfunction.
A. Csiszar, S. Tarantini, A. Yabluchanskiy, Priya Balasubramanian +4 more
2019American Journal of Physiology. Heart and Circulatory Physiology35 citations Open access
Semantic Scholar
Chitosan nanoparticles release nimodipine in response to tissue acidosis to attenuate spreading depolarization evoked during forebrain ischemia.
Orsolya M. Tóth, Ákos Menyhárt, V. Varga, Dóra Hantosi +7 more
2019Neuropharmacology35 citations Open access
Semantic Scholar
Large-conductance Ca2+-activated potassium channels are potently involved in the inverse neurovascular response to spreading depolarization.
Ákos Menyhárt, A. Farkas, D. Varga, Rita Frank +7 more
2018Neurobiology of Disease32 citations Open access
Semantic Scholar
Effects of early aging and cerebral hypoperfusion on spreading depression in rats.
E. Farkas, T. Obrenovitch, A. Institoris, F. Bari
2011Neurobiology of Aging31 citations
Semantic Scholar
Impact of aging on spreading depolarizations induced by focal brain ischemia in rats.
D. Clark, A. Institoris, Gábor Kozák, Zsófia Bere +3 more
2014Neurobiology of Aging30 citations Open access
Semantic Scholar
Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus.
M. Hugyecz, E. Mracsko, P. Hertelendy, E. Farkas +2 more
2011Brain Research29 citations
Semantic Scholar
Preparation of novel tissue acidosis‐responsive chitosan drug nanoparticles: Characterization and in vitro release properties of Ca2+ channel blocker nimodipine drug molecules
L. Janovák, Árpád Turcsányi, É. Bozó, Á. Deák +8 more
2018European Journal of Pharmaceutical Sciences28 citations Open access
Semantic Scholar
The impact of dihydropyridine derivatives on the cerebral blood flow response to somatosensory stimulation and spreading depolarization
Írisz Szabó, Orsolya M. Tóth, Tony Alan Ratliff, D. Varga +8 more
2019British Journal of Pharmacology26 citations Open access
Semantic Scholar
Microglia alter the threshold of spreading depolarization and related potassium uptake in the mouse brain
D. Varga, Ákos Menyhárt, Balázs Pósfai, E. Császár +8 more
2020Journal of Cerebral Blood Flow and Metabolism25 citations Open access
Semantic Scholar

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F. Bari×22
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F. Bari — researcher profile on SciRah
S. Tarantini×18
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S. Tarantini — researcher profile on SciRah
A. Csiszar×18
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A. Csiszar — researcher profile on SciRah
Z. Ungvari×18
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A. Yabluchanskiy

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T. Kiss — researcher profile on SciRah

Ákos Menyhárt×13

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Priya Balasubramanian×9

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M. N. Valcarcel-Ares×7

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