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T. Wirth · SciRah

Researcher profile · Semantic Scholar

T. Wirth

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T. Wirth — researcher profile on SciRah

h-index: 71
Works: 379
Citations: 18K

Most-cited papers

Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses.
N. Woller, E. Gürlevik, B. Fleischmann-Mundt, A. Schumacher +8 more
2015Molecular Therapy193 citations Open access
Semantic Scholar
NF‐κB activation in astrocytes drives a stage‐specific beneficial neuroimmunological response in ALS
Najwa Ouali-Alami, Christine Schurr, Florian Olde Heuvel, Linyun Tang +18 more
2018EMBO Journal143 citations Open access
Semantic Scholar
Global DNA methylation analysis of human atherosclerotic plaques reveals extensive genomic hypomethylation and reactivation at imprinted locus 14q32 involving induction of a miRNA cluster.
E. Aavik, Henri Lumivuori, Olavi Leppänen, T. Wirth +8 more
2015European Heart Journal128 citations Open access
Semantic Scholar
Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins
D. Sauter, D. Hotter, B. Van Driessche, C. Stürzel +10 more
2015Cell Reports112 citations Open access
Semantic Scholar
Neoantigen Targeting—Dawn of a New Era in Cancer Immunotherapy?
T. Wirth, F. Kühnel
2017Frontiers in Immunology100 citations Open access
Semantic Scholar
Crosstalk between Tumor and Stromal Cells in Pancreatic Ductal Adenocarcinoma
Nadine Sperb, M. Tsesmelis, T. Wirth
2020International Journal of Molecular Sciences89 citations Open access
Semantic Scholar
Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells.
E. Gürlevik, B. Fleischmann-Mundt, J. Brooks, I. Demir +18 more
2016Gastroenterology81 citations Open access
Semantic Scholar
Tailored Tumor Immunogenicity Reveals Regulation of CD4 and CD8 T Cell Responses against Cancer.
Sarah Knocke, B. Fleischmann-Mundt, M. Saborowski, M. Manns +3 more
2016Cell Reports73 citations Open access
Semantic Scholar
Perioperative, Spatiotemporally Coordinated Activation of T and NK Cells Prevents Recurrence of Pancreatic Cancer.
J. Brooks, B. Fleischmann-Mundt, N. Woller, Julia Niemann +13 more
2018Cancer Research68 citations
Semantic Scholar
A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence
Patrick Meyer, P. Maity, Andre Burkovski, J. Schwab +9 more
2017PLoS Comput. Biol.68 citations Open access
Semantic Scholar
IKK2/NF-κB signaling protects neurons after traumatic brain injury
M. Mettang, S. Reichel, M. Lattke, Annette Palmer +5 more
2017The FASEB Journal65 citations Open access
Semantic Scholar
Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy
Julia Niemann, N. Woller, J. Brooks, B. Fleischmann-Mundt +9 more
2019Nature Communications62 citations Open access
Semantic Scholar
NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss
J. S. Schlett, M. Mettang, Aladdin Skaf, Pavel Schweizer +19 more
2023Molecular Neurodegeneration58 citations Open access
Semantic Scholar
The impact of the revolution in hepatitis C treatment on hepatocellular carcinoma.
T. Wirth, M. Manns
2016Annals of Oncology58 citations Open access
Semantic Scholar
Canonical NF‐κB signaling in hepatocytes acts as a tumor‐suppressor in hepatitis B virus surface antigen‐driven hepatocellular carcinoma by controlling the unfolded protein response
Yoshiaki Sunami, M. Ringelhan, E. Kókai, Miao Lu +21 more
2016Hepatology52 citations Open access
Semantic Scholar
STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI.
Florian Olde Heuvel, S. Holl, A. Chandrasekar, Zheng-Hui Li +15 more
2019Brain, behavior, and immunity50 citations
Semantic Scholar
CD40 Signaling Drives Potent Cellular Immune Responses in Heterologous Cancer Vaccinations.
S. Nimanong, D. Ostroumov, J. Wingerath, Sarah Knocke +6 more
2017Cancer Research38 citations Open access
Semantic Scholar
Oncogenic Akt-FOXO3 loop favors tumor-promoting modes and enhances oxidative damage-associated hepatocellular carcinogenesis
Miao Lu, D. Hartmann, R. Braren, Aayush Gupta +9 more
2019BMC Cancer37 citations Open access
Semantic Scholar
Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention.
Tracy O'Connor, Xiao-Lan Zhou, Jan Kosla, Arlind Adili +38 more
2019Cancer Cell37 citations Open access
Semantic Scholar
Tight regulation of FOXO1 is essential for maintenance of B-cell precursor acute lymphoblastic leukemia.
Fan Wang, Salih Demir, Franziska Gehringer, Clarissa D Osswald +9 more
2018Blood37 citations Open access
Semantic Scholar
Physiological levels of the PTEN-PI3K-AKT axis activity are required for maintenance of Burkitt lymphoma
Franziska Gehringer, S. Weissinger, P. Möller, T. Wirth +1 more
2019Leukemia36 citations Open access
Semantic Scholar
Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration
M. Lattke, S. Reichel, A. Magnutzki, A. Abaei +6 more
2017Molecular Neurodegeneration36 citations Open access
Semantic Scholar
FOXO in B-cell lymphopoiesis and B cell neoplasia.
A. Ushmorov, T. Wirth
2017Seminars in Cancer Biology35 citations
Semantic Scholar
Block of NF-kB signaling accelerates MYC-driven hepatocellular carcinogenesis and modifies the tumor phenotype towards combined hepatocellular cholangiocarcinoma.
Jia-Jia He, M. Gerstenlauer, L. Chan, F. Leithäuser +3 more
2019Cancer Letters34 citations Open access
Semantic Scholar
IKK2/NF-κB Activation in Astrocytes Reduces amyloid β Deposition: A Process Associated with Specific Microglia Polarization
Shu Yang, A. Magnutzki, Najwa Ouali Alami, M. Lattke +7 more
2021Cells33 citations Open access
Semantic Scholar
HCC Immune Surveillance and Antiviral Therapy of Hepatitis C Virus Infection
Solomon Owusu Sekyere, B. Schlevogt, F. Mettke, M. Kabbani +7 more
2018Liver Cancer32 citations Open access
Semantic Scholar
Surveillance in cholangiocellular carcinoma.
T. Wirth, A. Vogel
2016Best practice & research. Clinical gastroenterology29 citations
Semantic Scholar
Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis
Torsten Diesinger, V. Buko, A. Lautwein, R. Dvorský +17 more
2020PLoS ONE27 citations Open access
Semantic Scholar
Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS
Najwa Ouali-Alami, Linyun Tang, Diana Wiesner, Barbara Commisso +10 more
2020Life Science Alliance27 citations Open access
Semantic Scholar
Four in one—Combination therapy using live Lactococcus lactis expressing three therapeutic proteins for the treatment of chronic non-healing wounds
Jere Kurkipuro, I. Mierau, T. Wirth, H. Samaranayake +4 more
2022PLoS ONE26 citations Open access
Semantic Scholar
Epithelial NEMO/IKKγ limits fibrosis and promotes regeneration during pancreatitis
L. Chan, M. Gerstenlauer, B. Konukiewitz, K. Steiger +3 more
2016Gut26 citations
Semantic Scholar
Prospects and Challenges for T Cell-Based Therapies of HCC
N. Woller, S. Engelskircher, T. Wirth, H. Wedemeyer
2021Cells24 citations Open access
Semantic Scholar
The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1)
B. von Einem, Anke Wahler, Tobias G. Schips, A. Serrano-Pozo +8 more
2015PLoS ONE23 citations Open access
Semantic Scholar
CCND3 is indispensable for the maintenance of B-cell acute lymphoblastic leukemia
F. Ketzer, Hend Abdelrasoul, Mona Vogel, R. Marienfeld +4 more
2022Oncogenesis21 citations Open access
Semantic Scholar
Monocyte chemoattractant protein 1 as a potential biomarker for immune checkpoint inhibitor‐associated neurotoxicity
N. Möhn, Susann Mahjoub, Laura Duzzi, Emily Narten +12 more
2023Cancer Medicine20 citations Open access
Semantic Scholar
Activation of oncogenic pathways in classical Hodgkin lymphoma by decitabine: A rationale for combination with small molecular weight inhibitors.
T. Swerev, T. Wirth, A. Ushmorov
2017International Journal of Oncology20 citations
Semantic Scholar
Fine-tuning of FOXO3A in cHL as a survival mechanism and a hallmark of abortive plasma cell differentiation.
Clarissa D Osswald, Lin-ka Xie, Han-Feng Guan, F. Herrmann +7 more
2018Blood19 citations Open access
Semantic Scholar
FOXO1 Confers Maintenance of the Dark Zone Proliferation and Survival Program and Can Be Pharmacologically Targeted in Burkitt Lymphoma
Franziska Gehringer, S. Weissinger, L. Swier, P. Möller +2 more
2019Cancers18 citations Open access
Semantic Scholar
Accelerated aging in mice with astrocytic redox imbalance as a consequence of SOD2 deletion
Konstantinos Tsesmelis, Gandhari Maity-Kumar, Dana Croner, Jasmin Sprissler +4 more
2023Aging Cell16 citations Open access
Semantic Scholar
Neuronal redox imbalance results in altered energy homeostasis and early postnatal lethality
Gandhari Maity-Kumar, D. Thal, B. Baumann, K. Scharffetter-Kochanek +1 more
2015The FASEB Journal15 citations
Semantic Scholar
BOB.1/OBF.1 is required during B‐cell ontogeny for B‐cell differentiation and germinal center function
A. Betzler, K. Fiedler, T. Hoffmann, H. Fehling +2 more
2021European Journal of Immunology12 citations Open access
Semantic Scholar
The PMN-MDSC - a key player in glucocorticoid resistance following combined physical and psychosocial trauma.
E. Kempter, M. Amoroso, Sandra Kupfer, Ludmila Lupu +10 more
2022Brain, behavior, and immunity11 citations
Semantic Scholar
Functional IKK/NF-κB signaling in pancreatic stellate cells is essential to prevent autoimmune pancreatitis
L. Chan, M. Tsesmelis, M. Gerstenlauer, F. Leithäuser +4 more
2021Communications Biology11 citations Open access
Semantic Scholar
Recombinant LCMV Vectors Induce Protective Immunity following Homologous and Heterologous Vaccinations.
J. Wingerath, D. Ostroumov, N. Woller, M. Manns +5 more
2017Molecular Therapy11 citations Open access
Semantic Scholar
Requirement of the RNA-binding protein SmpB during intracellular growth of Listeria monocytogenes.
M. A. Mraheil, Renate Frantz, Lisa Teubner, H. Wendt +4 more
2017International Journal of Medical Microbiology10 citations
Semantic Scholar
NF‐κB‐dependent signals control BOB.1/OBF.1 and Oct2 transcriptional activity in B cells
Melanie Kilzheimer, Jasmin Quandt, J. Langhans, Petra Weihrich +2 more
2015European Journal of Immunology9 citations Open access
Semantic Scholar
A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma
Torsten Diesinger, A. Lautwein, Sebastian Bergler, D. Buckert +17 more
2021Canadian Journal of Gastroenterology and Hepatology8 citations Open access
Semantic Scholar
T Cell Specific BOB.1/OBF.1 Expression Promotes Germinal Center Response and T Helper Cell Differentiation
A. Betzler, J. Ezić, T. Abou Kors, T. Hoffmann +2 more
2022Frontiers in Immunology7 citations Open access
Semantic Scholar
High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections – Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils
N. Aaltonen, P. Singha, Hermina Jakupović, T. Wirth +11 more
2020Biological Procedures Online6 citations Open access
Semantic Scholar
Elevated β-cell stress levels promote severe diabetes development in mice with MODY4
Bernadette M Trojanowski, H. Salem, H. Neubauer, E. Simon +6 more
2019Journal of Endocrinology6 citations Open access
Semantic Scholar

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