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Anthony K. Mittermaier · SciRah

Researcher profile · Semantic Scholar

Anthony K. Mittermaier

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Anthony K. Mittermaier — researcher profile on SciRah

h-index: 32
Works: 87
Citations: 4,067

Most-cited papers

New Tools Provide New Insights in NMR Studies of Protein Dynamics
Anthony K. Mittermaier, L. Kay
2006Science715 citations
Semantic Scholar
Studying excited states of proteins by NMR spectroscopy
F. Mulder, Anthony K. Mittermaier, Bin Hon, F. Dahlquist +1 more
2001Nature Structural Biology382 citations
Semantic Scholar
Observing biological dynamics at atomic resolution using NMR.
Anthony K. Mittermaier, L. Kay
2009TIBS -Trends in Biochemical Sciences. Regular ed311 citations
Semantic Scholar
Covalent inhibitors design and discovery.
Stephane de Cesco, Jerry Kurian, C. Dufresne, Anthony K. Mittermaier +1 more
2017European journal of medicinal chemistry267 citations
Semantic Scholar
A simple in vivo assay for increased protein solubility
K. Maxwell, Anthony K. Mittermaier, J. Forman-Kay, A. Davidson
1999Protein Science169 citations Open access
Semantic Scholar
Slow internal dynamics in proteins: application of NMR relaxation dispersion spectroscopy to methyl groups in a cavity mutant of T4 lysozyme.
F. Mulder, Bin Hon, Anthony K. Mittermaier, F. Dahlquist +1 more
2002Journal of the American Chemical Society112 citations
Semantic Scholar
Binding mechanism of an SH3 domain studied by NMR and ITC.
J. Demers, Anthony K. Mittermaier
2009Journal of the American Chemical Society111 citations
Semantic Scholar
COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms
R. Malone, Philip A. Tisdall, Philip Fremont-Smith, Yongfeng Liu +23 more
2020Frontiers in Pharmacology105 citations Open access
Semantic Scholar
Multiple-site exchange in proteins studied with a suite of six NMR relaxation dispersion experiments: an application to the folding of a Fyn SH3 domain mutant.
D. Korzhnev, Philipp Neudecker, Anthony K. Mittermaier, V. Orekhov +1 more
2005Journal of the American Chemical Society91 citations
Semantic Scholar
Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme
Lee A. Freiburger, Oliver M. Baettig, T. Sprules, A. Berghuis +2 more
2011Nature Structural &Molecular Biology78 citations Open access
Semantic Scholar
Enzyme Kinetics by Isothermal Titration Calorimetry: Allostery, Inhibition, and Dynamics
Yun Wang, Guanyu Wang, N. Moitessier, Anthony K. Mittermaier
2020Frontiers in Molecular Biosciences65 citations Open access
Semantic Scholar
Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors
J. Stille, J. Tjutrins, Guanyu Wang, F. A. Venegas +16 more
2021European journal of medicinal chemistry63 citations Open access
Semantic Scholar
Analysis of deuterium relaxation-derived methyl axis order parameters and correlation with local structure
Anthony K. Mittermaier, L. Kay, J. Forman-Kay
1999Journal of Biomolecular NMR63 citations
Semantic Scholar
Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry
J. D. Di Trani, Stephane de Cesco, Rebecca O'Leary, J. Plescia +3 more
2018Nature Communications61 citations Open access
Semantic Scholar
Protein stabilization by specific binding of guanidinium to a functional arginine‐binding surface on an SH3 domain
A. Zarrine-Afsar, Anthony K. Mittermaier, L. Kay, A. Davidson
2006Protein Science61 citations Open access
Semantic Scholar
An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR
S. Vahidi, Z. A. Ripstein, Jordan B. Juravsky, E. Rennella +4 more
2019Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
Stabilization of i-motif structures by 2′-β-fluorination of DNA
H. Assi, Robert W. Harkness, N. Martín-Pintado, C. Wilds +4 more
2016Nucleic Acids Research59 citations Open access
Semantic Scholar
Elucidating Protein Binding Mechanisms by Variable‐c ITC
Lee A. Freiburger, K. Auclair, Anthony K. Mittermaier
2009ChemBioChem55 citations Open access
Semantic Scholar
G-quadruplex dynamics.
Robert W. Harkness, Anthony K. Mittermaier
2017Biochimica et Biophysica Acta - Proteins and Proteomics51 citations
Semantic Scholar
Virtual screening and computational optimization for the discovery of covalent prolyl oligopeptidase inhibitors with activity in human cells.
Stéphane De Cesco, Sébastien Deslandes, Eric Therrien, David Levan +6 more
2012Journal of Medicinal Chemistry50 citations Open access
Semantic Scholar
The effects of mutations on motions of side-chains in protein L studied by 2H NMR dynamics and scalar couplings.
Ó. Millet, Anthony K. Mittermaier, D. Baker, L. Kay
2003Journal of Molecular Biology50 citations
Semantic Scholar
Efficient and Rapid Mechanochemical Assembly of Platinum(II) Squares for Guanine Quadruplex Targeting.
Amine Garci, Katherine J. Castor, Johans F Fakhoury, Jean-Louis Do +6 more
2017Journal of the American Chemical Society47 citations Open access
Semantic Scholar
G-register exchange dynamics in guanine quadruplexes
Robert W. Harkness, Anthony K. Mittermaier
2016Nucleic Acids Research42 citations Open access
Semantic Scholar
Relaxation dispersion NMR spectroscopy for the study of protein allostery
Patrick J. Farber, Anthony K. Mittermaier
2015Biophysical Reviews42 citations Open access
Semantic Scholar
Platinum(II) Phenanthroimidazoles for Targeting Telomeric G‐Quadruplexes
Katherine J. Castor, J. Mancini, Johans J. Fakhoury, Nathanael Weill +7 more
2012ChemMedChem39 citations
Semantic Scholar
Global ITC fitting methods in studies of protein allostery.
Lee A. Freiburger, K. Auclair, Anthony K. Mittermaier
2015Methods38 citations Open access
Semantic Scholar
Analyzing protein folding cooperativity by differential scanning calorimetry and NMR spectroscopy.
Patrick J. Farber, Hariyanto Darmawan, T. Sprules, Anthony K. Mittermaier
2010Journal of the American Chemical Society37 citations
Semantic Scholar
The response of internal dynamics to hydrophobic core mutations in the SH3 domain from the Fyn tyrosine kinase
Anthony K. Mittermaier, L. Kay
2004Protein Science36 citations Open access
Semantic Scholar
Applications of isothermal titration calorimetry in pure and applied research from 2016 to 2020
R. Falconer, B. Schuur, Anthony K. Mittermaier
2021Journal of Molecular Recognition35 citations Open access
Semantic Scholar
Amplified Self-Immolative Release of Small Molecules by Spatial Isolation of Reactive Groups on DNA-Minimal Architectures.
Alexander L. Prinzen, Daniel Saliba, Christopher D Hennecker, Tuan Trinh +2 more
2020Angewandte Chemie34 citations
Semantic Scholar
Exploring the role of post‐translational modifications in regulating α‐synuclein interactions by studying the effects of phosphorylation on nanobody binding
Farah El-Turk, E. De Genst, Tim Guilliams, Bruno Fauvet +7 more
2018Protein Science33 citations Open access
Semantic Scholar
Concerted dynamics link allosteric sites in the PBX homeodomain.
Patrick J. Farber, Anthony K. Mittermaier
2011Journal of Molecular Biology33 citations
Semantic Scholar
Measuring Rapid Time-Scale Reaction Kinetics Using Isothermal Titration Calorimetry.
J. D. Di Trani, N. Moitessier, Anthony K. Mittermaier
2017Analytical Chemistry32 citations Open access
Semantic Scholar
Correlation between 2H NMR side-chain order parameters and sequence conservation in globular proteins.
Anthony K. Mittermaier, A. Davidson, L. Kay
2003Journal of the American Chemical Society31 citations
Semantic Scholar
Mapping the energy landscapes of supramolecular assembly by thermal hysteresis
Robert W. Harkness V, N. Avakyan, H. Sleiman, Anthony K. Mittermaier
2018Nature Communications30 citations Open access
Semantic Scholar
Protein alignment using cellulose nanocrystals: practical considerations and range of application
A. Denisov, Elisabeth Kloser, D. Gray, Anthony K. Mittermaier
2010Journal of Biomolecular NMR30 citations
Semantic Scholar
Side-chain interactions in the folding pathway of a Fyn SH3 domain mutant studied by relaxation dispersion NMR spectroscopy.
Anthony K. Mittermaier, D. Korzhnev, L. Kay
2005Biochemistry29 citations
Semantic Scholar
A platinum(II) phenylphenanthroimidazole with an extended side-chain exhibits slow dissociation from a c-Kit G-quadruplex motif.
Katherine J. Castor, Zhaomin Liu, Johans J. Fakhoury, Mark A. Hancock +3 more
2013Chemistry28 citations
Semantic Scholar
NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain.
P. Finerty, Anthony K. Mittermaier, R. Muhandiram, L. Kay +1 more
2005Biochemistry28 citations
Semantic Scholar
Substrate-dependent switching of the allosteric binding mechanism of a dimeric enzyme.
Lee A. Freiburger, T. Miletti, Siqi Zhu, Oliver M. Baettig +3 more
2014Nature Chemical Biology26 citations
Semantic Scholar
Structural Effects of Two Camelid Nanobodies Directed to Distinct C-Terminal Epitopes on α-Synuclein.
Farah El-Turk, Francisco N. Newby, E. De Genst, Tim Guilliams +4 more
2016Biochemistry25 citations
Semantic Scholar
Measurement of (13)C(alpha)-(13)C(beta) dipolar couplings in (15)N,(13)C,(2)H-labeled proteins: application to domain orientation in maltose binding protein.
J. Evenäs, Anthony K. Mittermaier, Daiwen Yang, L. Kay
2001Journal of the American Chemical Society25 citations
Semantic Scholar
Complete Kinetic Characterization of Enzyme Inhibition in a Single Isothermal Titration Calorimetric Experiment.
J. D. Di Trani, N. Moitessier, Anthony K. Mittermaier
2018Analytical Chemistry23 citations
Semantic Scholar
3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors.
Gaëlle Mariaule, Stephane de Cesco, F. Airaghi, Jerry Kurian +6 more
2016Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Effect of deuteration on some structural parameters of methyl groups in proteins as evaluated by residual dipolar couplings
Anthony K. Mittermaier, L. Kay
2002Journal of Biomolecular NMR23 citations
Semantic Scholar
Frustrated folding of guanine quadruplexes in telomeric DNA
S. Carrino, Christopher D Hennecker, Ana C. Murrieta, Anthony K. Mittermaier
2021Nucleic Acids Research21 citations Open access
Semantic Scholar
Electrostatic Interactions in the Binding Pathway of a Transient Protein Complex Studied by NMR and Isothermal Titration Calorimetry*
Erick Meneses, Anthony K. Mittermaier
2014Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Van't Hoff global analyses of variable temperature isothermal titration calorimetry data.
Lee A. Freiburger, K. Auclair, Anthony K. Mittermaier
2012Thermochimica Acta19 citations Open access
Semantic Scholar
Local folding and misfolding in the PBX homeodomain from a three-state analysis of CPMG relaxation dispersion NMR data.
Patrick J. Farber, J. Slager, Anthony K. Mittermaier
2012Journal of Physical Chemistry B19 citations Open access
Semantic Scholar
Rapid characterization of folding and binding interactions with thermolabile ligands by DSC.
Robert W. Harkness, Sladjana Slavkovic, Philip E. Johnson, Anthony K. Mittermaier
2016Chemical Communications18 citations Open access
Semantic Scholar

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L. Kay — researcher profile on SciRah
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K. Auclair×6
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J. D. Di Trani — researcher profile on SciRah

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Robert W. Harkness×4

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