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Ewa P. Malc · SciRah

Researcher profile · Semantic Scholar

Ewa P. Malc

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Ewa P. Malc — researcher profile on SciRah

h-index: 25
Works: 35
Citations: 3,482

Most-cited papers

Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma
M. Gillette, Shankha Satpathy, Song Cao, S. Dhanasekaran +182 more
2020Cell713 citations Open access
Semantic Scholar
Proteogenomic Characterization of Endometrial Carcinoma
Yong-Chao Dou, Emily A. Kawaler, Daniel Cui Zhou, M. Gritsenko +214 more
2020Cell416 citations Open access
Semantic Scholar
Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions
Steven A. Roberts, J. Sterling, Cole Thompson, S. Harris +8 more
2012Molecules and Cells406 citations Open access
Semantic Scholar
An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers
Kin Chan, Steven A. Roberts, L. Klimczak, J. Sterling +8 more
2015Nature Genetics394 citations Open access
Semantic Scholar
APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication
James I Hoopes, Luis M. Cortez, Tony M. Mertz, Ewa P. Malc +2 more
2016Cell Reports197 citations Open access
Semantic Scholar
Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation
A. Clausen, S. Lujan, A. Burkholder, Clinton D. Orebaugh +7 more
2015Nature Structural &Molecular Biology192 citations Open access
Semantic Scholar
Break-Induced Replication is a Source of Mutation Clusters Underlying Kataegis
Cynthia J. Sakofsky, Steven A. Roberts, Ewa P. Malc, P. Mieczkowski +3 more
2014Cell Reports166 citations Open access
Semantic Scholar
Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition
S. Lujan, A. Clausen, Alan B. Clark, Heather K. MacAlpine +7 more
2014Genome Research151 citations Open access
Semantic Scholar
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts
Natalie Saini, Steven A. Roberts, L. Klimczak, Kin Chan +13 more
2016PLoS Genetics91 citations Open access
Semantic Scholar
Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity
Peng Mao, Alexander J. Brown, Ewa P. Malc, P. Mieczkowski +3 more
2017Genome Research86 citations Open access
Semantic Scholar
Gene Copy-Number Variation in Haploid and Diploid Strains of the Yeast Saccharomyces cerevisiae
Hengshan Zhang, A. F. Zeidler, Wei Song, Christopher M. Puccia +5 more
2013Genetics86 citations Open access
Semantic Scholar
High-Resolution Genome-Wide Analysis of Irradiated (UV and γ-Rays) Diploid Yeast Cells Reveals a High Frequency of Genomic Loss of Heterozygosity (LOH) Events
Jordan St. Charles, Einat Hazkani-Covo, Yi Yin, Sabrina L. Andersen +5 more
2012Genetics81 citations Open access
Semantic Scholar
Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation
Cynthia J. Sakofsky, Natalie Saini, L. Klimczak, Kin Chan +5 more
2019PLoS Biology46 citations Open access
Semantic Scholar
Repair of oxidative damage in mitochondrial DNA of Saccharomyces cerevisiae: involvement of the MSH1-dependent pathway.
P. Dzierzbicki, P. Koprowski, M. Fikus, Ewa P. Malc +1 more
2004DNA Repair44 citations
Semantic Scholar
Mutation signatures specific to DNA alkylating agents in yeast and cancers.
Natalie Saini, J. Sterling, Cynthia J. Sakofsky, Camille K Giacobone +5 more
2020Nucleic Acids Research43 citations Open access
Semantic Scholar
Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements
Rajula Elango, B. Osia, Victoria Harcy, Ewa P. Malc +3 more
2019Nucleic Acids Research42 citations Open access
Semantic Scholar
APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast
Natalie Saini, Steven A. Roberts, J. Sterling, Ewa P. Malc +2 more
2017DNA Repair42 citations Open access
Semantic Scholar
Variant calling in low-coverage whole genome sequencing of a Native American population sample
C. Bizon, M. Spiegel, S. Chasse, I. Gizer +7 more
2014BMC Genomics41 citations Open access
Semantic Scholar
Atypical UV Photoproducts Induce Non-canonical Mutation Classes Associated with Driver Mutations in Melanoma
Marian F. Laughery, Alexander J. Brown, K. Bohm, S. Sivapragasam +9 more
2020Cell Reports35 citations Open access
Semantic Scholar
Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages
Y. Fang, Marco A. Coelho, Haidong Shu, Klaas Schotanus +12 more
2019bioRxiv33 citations Open access
Semantic Scholar
Cavitation Enhancing Nanodroplets Mediate Efficient DNA Fragmentation in a Bench Top Ultrasonic Water Bath
S. Kasoji, S. Pattenden, Ewa P. Malc, Chatura N. Jayakody +4 more
2015PLoS ONE30 citations Open access
Semantic Scholar
Metabolic Potential, Ecology and Presence of Associated Bacteria Is Reflected in Genomic Diversity of Mucoromycotina
Anna Muszewska, A. Okrasińska, Kamil Steczkiewicz, Olga Drgas +11 more
2021Frontiers in Microbiology27 citations Open access
Semantic Scholar
Characterization of systemic genomic instability in budding yeast
Nadia M. V. Sampaio, V. Ajith, R. Watson, Lydia R. Heasley +6 more
2020Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
Msh1p counteracts oxidative lesion-induced instability of mtDNA and stimulates mitochondrial recombination in Saccharomyces cerevisiae.
A. Kaniak, P. Dzierzbicki, Agata Rogowska, Ewa P. Malc +2 more
2009DNA Repair26 citations
Semantic Scholar
Inactivation of the 20S proteasome maturase, Ump1p, leads to the instability of mtDNA in Saccharomyces cerevisiae.
Ewa P. Malc, P. Dzierzbicki, A. Kaniak, Adrianna Skoneczna +1 more
2009Mutation research25 citations
Semantic Scholar
A Case Study of Genomic Instability in an Industrial Strain of Saccharomyces cerevisiae
Aline Rodrigues-Prause, Nadia M. V. Sampaio, Theodore Gurol, G. Aguirre +10 more
2018G3: Genes, Genomes, Genetics19 citations Open access
Semantic Scholar
The generation of oxidative stress-induced rearrangements in Saccharomyces cerevisiae mtDNA is dependent on the Nuc1 (EndoG/ExoG) nuclease and is enhanced by inactivation of the MRX complex.
P. Dzierzbicki, Aneta Kaniak-Golik, Ewa P. Malc, P. Mieczkowski +1 more
2012Mutation research13 citations
Semantic Scholar
Congenital Midline Cervical Cleft: First Report and Genetic Analysis of Two Related Patients
M. Masood, P. Mieczkowski, Ewa P. Malc, A. K. Foreman +3 more
2020Annals of Otology, Rhinology and Laryngology9 citations Open access
Semantic Scholar
The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions
Braulio Bonilla, Alexander J. Brown, S. R. Hengel, Kyle Rapchak +13 more
2021bioRxiv6 citations Open access
Semantic Scholar
Mitotic systemic genomic instability in yeast
Nadia M. V. Sampaio, Aline Rodrigues-Prause, V. Ajith, Theodore Gurol +10 more
2017bioRxiv4 citations Open access
Semantic Scholar
Variant calling in low-coverage whole genome sequencing of a Native American population sample
C. Bizon, M. Spiegel, S. Chasse, I. Gizer +7 more
2014BMC Genomics1 citations Open access
Semantic Scholar
Author response: The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions
Braulio Bonilla, Alexander J. Brown, S. R. Hengel, Kyle Rapchak +13 more
20210 citations Open access
Semantic Scholar
Correction: Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation
Cynthia J. Sakofsky, Natalie Saini, L. Klimczak, Kin Chan +5 more
2020PLoS Biology0 citations Open access
Semantic Scholar
Metabolic potential, ecology and presence of endohyphal bacteria is reflected in genomic diversity of Mucoromycotina
Anna Muszewska, Alicja Okrasińska, Kamil Steczkiewicz, Olga Drgas +11 more
2020bioRxiv0 citations Open access
Semantic Scholar
Corrigendum to "APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast" [DNA Repair 53 (2017) 4-14].
Natalie Saini, Steven A. Roberts, J. Sterling, Ewa P. Malc +2 more
2019DNA Repair0 citations
Semantic Scholar

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