B. Trapp

Most-cited papers

Pathological mechanisms in progressive multiple sclerosis.
Don H. Mahad, B. Trapp, H. Lassmann
2015Lancet Neurology1,075 citations
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Activation of necroptosis in multiple sclerosis
D. Ofengeim, Yasushi Ito, Ayaz Najafov, Yao-Yang Zhang +15 more
2015Cell Reports507 citations Open access
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Mechanisms of Neuronal Dysfunction and Degeneration in Multiple Sclerosis
Ranjan Dutta, B. Trapp
2010Progress in neurobiology450 citations Open access
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Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4
Zhihong Chen, Walid Jalabi, Karl B. Shpargel, Kenneth T. Farabaugh +6 more
2012Journal of Neuroscience411 citations Open access
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Microglia and neuroprotection
Zhihong Chen, B. Trapp
2016Journal of Neurochemistry383 citations Open access
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Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2
Jacob A. Sloane, C. Batt, Yuguo Ma, Z. Harris +2 more
2010Proceedings of the National Academy of Sciences of the United States of America348 citations Open access
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Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain
Zhihong Chen, Walid Jalabi, Wei-Wei Hu, Hyun-Joo Park +7 more
2014Nature Communications303 citations Open access
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Target identification among known drugs by deep learning from heterogeneous networks
Xiangxiang Zeng, Siyi Zhu, Wei-Qiang Lu, Zehui Liu +11 more
2020Chemical Science269 citations Open access
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Epigenome-wide differences in pathology-free regions of multiple sclerosis–affected brains
J. L. Huynh, Paras Garg, T. Thin, S. Yoo +7 more
2013Nature Neuroscience255 citations Open access
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Relapsing and progressive forms of multiple sclerosis – insights from pathology
Ranjan Dutta, B. Trapp
2014Current Opinion in Neurology233 citations Open access
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Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells
Zi-Zhen Kang, Chen-Hui Wang, J. Zepp, Ling Wu +7 more
2013Nature Neuroscience211 citations Open access
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Myelination and axonal electrical activity modulate the distribution and motility of mitochondria at CNS nodes of Ranvier
N. Ohno, G. Kidd, D. Mahad, S. Kiryu-Seo +3 more
2011Journal of Neuroscience184 citations Open access
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Demyelination increases axonal stationary mitochondrial size and the speed of axonal mitochondrial transport
S. Kiryu-Seo, N. Ohno, G. Kidd, H. Komuro +1 more
2010Journal of Neuroscience173 citations Open access
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Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis.
J. Zambonin, Chao Zhao, N. Ohno, Graham R. Campbell +10 more
2011Brain : a journal of neurology160 citations Open access
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Gut microbes impact stroke severity via the trimethylamine-N-oxide pathway
Wei-Fei Zhu, K. Romano, Lin Li, J. Buffa +14 more
2021Cell Host and Microbe148 citations Open access
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Biology of Schwann cells.
G. Kidd, N. Ohno, B. Trapp
2013Handbook of Clinical Neurology146 citations
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MECHANISMS UNDERLYING PROGRESSION IN MULTIPLE SCLEROSIS
M. Absinta, H. Lassmann, B. Trapp
2020Current Opinion in Neurology142 citations Open access
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Cortical neuronal loss and cerebral white matter demyelination in multiple sclerosis: a retrospective study
B. Trapp, Megan Vignos, J. Dudman, Ansi Chang +10 more
2018Lancet Neurology134 citations Open access
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Cleavage of Neuregulin-1 by BACE1 or ADAM10 Protein Produces Differential Effects on Myelination*
Xiaoyang Luo, Marguerite Prior, Wan-Xia He, Xiangyou Hu +7 more
2011Journal of Biological Chemistry118 citations Open access
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Glutamate receptors on myelinated spinal cord axons: I) GluR6 kainate receptors
M. Ouardouz, E. Coderre, A. Basak, Andrew Chen +6 more
2009Annals of Neurology117 citations Open access
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Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons
N. Ohno, Hao Chiang, D. Mahad, G. Kidd +5 more
2014Proceedings of the National Academy of Sciences of the United States of America108 citations Open access
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pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis
D. Kremer, J. Gruchot, V. Weyers, Lisa Oldemeier +10 more
2019Proceedings of the National Academy of Sciences of the United States of America107 citations Open access
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Clinically feasible MTR is sensitive to cortical demyelination in MS
Jacqueline T. Chen, Kathryn Easley, Colleen Schneider, Kunio Nakamura +7 more
2013Neurology98 citations Open access
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A histone deacetylase 3–dependent pathway delimits peripheral myelin growth and functional regeneration
Xue-Lian He, Liguo Zhang, L. Queme, Xue-Zhao Liu +13 more
2018Nature Medicine89 citations Open access
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Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis
Simon Licht-Mayer, Graham R. Campbell, Marco A Cañizares, A. Mehta +33 more
2020Acta Neuropathologica88 citations Open access
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Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis
Carine Savarin, D. Hinton, A. Valentin-Torres, Zhihong Chen +3 more
2015Journal of Neuroinflammation87 citations Open access
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Axonal loss in multiple sclerosis: causes and mechanisms.
Gerson A. Criste, B. Trapp, Ranjan Dutta
2014Handbook of Clinical Neurology87 citations
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Alterations in CA1 hippocampal synapses in a mouse model of Fragile X Syndrome
S. Jawaid, G. Kidd, Jing Wang, Carrie Swetlik +2 more
2017Glia86 citations Open access
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Activated microglia enhance neurogenesis via trypsinogen secretion
A. Nikolakopoulou, Ranjan Dutta, Zhihong Chen, Robert H. Miller +1 more
2013Proceedings of the National Academy of Sciences of the United States of America76 citations Open access
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Hippocampal Volume Is Related to Cognitive Decline and Fornicial Diffusion Measures in Multiple Sclerosis
K. Koenig, K. Sakaie, M. Lowe, Jian Lin +6 more
2013Magnetic Resonance Imaging73 citations Open access
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DNA methylation in demyelinated multiple sclerosis hippocampus
Anthony Chomyk, Christina M. Volsko, A. Tripathi, Sadie A. Deckard +3 more
2017Scientific Reports63 citations Open access
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Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures.
Yu-shan Wan, Bo Feng, Yi You, Jie Yu +6 more
2020Cell Reports62 citations Open access
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Intrinsic and Extrinsic Mechanisms of Thalamic Pathology in Multiple Sclerosis
K. Mahajan, Kunio Nakamura, Jeffrey A. Cohen, B. Trapp +1 more
2020Annals of Neurology61 citations Open access
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Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination
A. Tripathi, Christina M. Volsko, J. P. Garcia, E. Agirre +6 more
2019Cell Reports60 citations Open access
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Gray-matter injury in multiple sclerosis.
R. Rudick, B. Trapp
2009New England Journal of Medicine59 citations
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Proteolipid protein–deficient myelin promotes axonal mitochondrial dysfunction via altered metabolic coupling
Xinghua Yin, G. Kidd, N. Ohno, G. Perkins +5 more
2016Journal of Cell Biology56 citations Open access
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A mouse model for testing remyelinating therapies
C. Bai, Sunny Sun, A. Roholt, Emily K. Benson +6 more
2016Experimental Neurology53 citations Open access
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Clonal Expansion of Mitochondrial DNA Deletions in Multiple Sclerosis
Graham R. Campbell, Yevgenya Kraytsberg, K. J. Krishnan, N. Ohno +9 more
2012Acta Neuropathologica48 citations Open access
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The relationship between cognitive function and high-resolution diffusion tensor MRI of the cingulum bundle in multiple sclerosis
K. Koenig, K. Sakaie, M. Lowe, Jian Lin +6 more
2015Multiple Sclerosis46 citations Open access
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Relapses in multiple sclerosis: Relationship to disability.
D. Goodin, A. Reder, R. Bermel, G. Cutter +10 more
2016Multiple Sclerosis and Related Disorders45 citations
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Discrepancy in CCL2 and CCR2 expression in white versus grey matter hippocampal lesions of Multiple Sclerosis patients
M. Prins, Ranjan Dutta, B. Baselmans, J. Brevé +8 more
2014Acta Neuropathologica Communications42 citations Open access
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Hippocampal Neurogenesis and Neural Circuit Formation in a Cuprizone-Induced Multiple Sclerosis Mouse Model
Hai Zhang, Yeonghwan Kim, E. J. Ro, Cindy Ho +3 more
2019Journal of Neuroscience40 citations Open access
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Axonal and Schwann Cell BACE1 Is Equally Required for Remyelination of Peripheral Nerves
Xiangyou Hu, Jinxuan Hu, Lu Dai, B. Trapp +1 more
2015Journal of Neuroscience39 citations Open access
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The role of the thalamus and hippocampus in episodic memory performance in patients with multiple sclerosis
K. Koenig, Stephen M. Rao, M. Lowe, Jian Lin +5 more
2018Multiple Sclerosis38 citations Open access
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Gene Expression Profiling in Multiple Sclerosis Brain
Ranjan Dutta, B. Trapp
2010Neurobiology of Disease34 citations Open access
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Lateral cerebellar nucleus stimulation promotes motor recovery and suppresses neuroinflammation in a fluid percussion injury rodent model.
H. Chan, C. Wathen, Nicole D. Mathews, O. Hogue +8 more
2018Brain Stimulation33 citations Open access
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Interleukin‐10 is a critical regulator of white matter lesion containment following viral induced demyelination
Shweta S. Puntambekar, D. Hinton, Xinghua Yin, Carine Savarin +3 more
2015Glia32 citations Open access
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Mitochondrial fission augments capsaicin-induced axonal degeneration
Hao Chiang, N. Ohno, Yu-Lin Hsieh, D. Mahad +4 more
2014Acta Neuropathologica29 citations Open access
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Sensitivity of T1/T2-weighted ratio in detection of cortical demyelination is similar to magnetization transfer ratio using post-mortem MRI
Yufan Zheng, J. Dudman, Jacqueline T. Chen, K. Mahajan +5 more
2021Multiple Sclerosis26 citations Open access
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Brain fibrinogen deposition plays a key role in MS pathophysiology - Yes
Dimitrios Davalos, K. Mahajan, B. Trapp
2019Multiple Sclerosis26 citations Open access
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