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W. Scholz · SciRah

Researcher profile · Semantic Scholar

W. Scholz

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W. Scholz — researcher profile on SciRah

h-index: 14
Works: 35
Citations: 992

Most-cited papers

18F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels–Alder Click Chemistry
Jan-Philip Meyer, J. Houghton, P. Kozlowski, D. Abdel-Atti +5 more
2015Bioconjugate chemistry153 citations Open access
Semantic Scholar
Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses
J. Houghton, Brian M. Zeglis, D. Abdel-Atti, Ritsuko Sawada +2 more
2015Journal of Nuclear Medicine98 citations Open access
Semantic Scholar
Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer
J. Houghton, Brian M. Zeglis, D. Abdel-Atti, R. Aggeler +4 more
2015Proceedings of the National Academy of Sciences of the United States of America93 citations Open access
Semantic Scholar
Human Monoclonal Anti-Protective Antigen Antibody Completely Protects Rabbits and Is Synergistic with Ciprofloxacin in Protecting Mice and Guinea Pigs against Inhalation Anthrax
J. W. Peterson, Jason E. Comer, David M. Noffsinger, A. Wenglikowski +7 more
2006Infection and Immunity89 citations Open access
Semantic Scholar
Establishment of the in vivo efficacy of pretargeted radioimmunotherapy utilizing inverse electron demand Diels-Alder click chemistry
J. Houghton, Rosemery Membreno, D. Abdel-Atti, K. Cunanan +5 more
2016Molecular Cancer Therapeutics82 citations Open access
Semantic Scholar
Leveraging bioorthogonal click chemistry to improve 225Ac-radioimmunotherapy of pancreatic ductal adenocarcinoma
S. Poty, L. Carter, Komal Mandleywala, Rosemery Membreno +5 more
2018Clinical Cancer Research75 citations Open access
Semantic Scholar
Human Monoclonal Antibodies to Sialyl-Lewis a (CA19.9) with Potent CDC, ADCC and Anti-Tumor Activity
Ritsuko Sawada, S. Sun, Xiao-Hong Wu, Feng Hong +3 more
2011Clinical Cancer Research66 citations Open access
Semantic Scholar
Applying PET to Broaden the Diagnostic Utility of the Clinically Validated CA19.9 Serum Biomarker for Oncology
Nerissa T. Viola-Villegas, Samuel L. Rice, S. Carlin, Xiao-Hong Wu +8 more
2013Journal of Nuclear Medicine62 citations Open access
Semantic Scholar
Human Monoclonal Antibody AVP-21D9 to Protective Antigen Reduces Dissemination of the Bacillus anthracis Ames Strain from the Lungs in a Rabbit Model
J. W. Peterson, Jason E. Comer, W. Baze, David M. Noffsinger +15 more
2007Infection and Immunity60 citations Open access
Semantic Scholar
Retooling a Blood-based Biomarker: Phase I Assessment of the High-Affinity CA19-9 Antibody HuMab-5B1 for Immuno-PET Imaging of Pancreatic Cancer
C. Lohrmann, E. O'Reilly, J. O'Donoghue, N. Pandit-Taskar +8 more
2019Clinical Cancer Research53 citations Open access
Semantic Scholar
Hypericum perforatum and Its Ingredients Hypericin and Pseudohypericin Demonstrate an Antiviral Activity against SARS-CoV-2
F. F. Mohamed, D. Anhlan, Michael Schöfbänker, A. Schreiber +7 more
2022Pharmaceuticals50 citations Open access
Semantic Scholar
Preloading with Unlabeled CA19.9 Targeted Human Monoclonal Antibody Leads to Improved PET Imaging with 89Zr-5B1
J. Houghton, D. Abdel-Atti, W. Scholz, J. Lewis
2017Molecular Pharmaceutics36 citations Open access
Semantic Scholar
The inverse electron-demand Diels-Alder reaction as a new methodology for the synthesis of 225Ac-labelled radioimmunoconjugates
Sophie Poty, Rosemery Membreno, J. Glaser, A. Ragupathi +3 more
2018Chemical Communications30 citations Open access
Semantic Scholar
Tumor-Specific Zr-89 Immuno-PET Imaging in a Human Bladder Cancer Model
Freddy E. Escorcia, Jeffrey M. Steckler, D. Abdel-Atti, E. Price +4 more
2018Molecular Imaging and Biology26 citations Open access
Semantic Scholar
A monoclonal antibody detecting dipeptidylpeptidase IV in human tissue
A. Feller, H. Radzun, E. Heymann, H. Haas +2 more
2004Virchows Archiv9 citations
Semantic Scholar
Abstract A73: Antitumor activity of MVT-5873, a monoclonal antibody targeting sialyl Lewisa, alone and in combination with gemcitabine/nab-paclitaxel in a BxPC3 human pancreatic cancer xenograft model
G. Ragupathi, Xiao-Hong Wu, P. Livingston, W. Scholz +2 more
20163 citations
Semantic Scholar
A pilot study of vaccination with sialyl Lewisa (sLea)-keyhole limpet hemocyanin (KLH) conjugate plus the immunologic adjuvant QS-21 in metastatic breast cancer patients (pts).
A. Diab, Govindaswami Ragupathi, W. Scholz, K. Panageas +3 more
2011Journal of Clinical Oncology2 citations
Semantic Scholar
Leveraging 225Ac-pretargeted radioimmunotherapy for application in pancreatic ductal adenocarcinoma therapy
S. Poty, Komal Mandleywala, L. Carter, D. Abdel-Atti +4 more
20181 citations
Semantic Scholar
Abstract 3036: PEGylated hyaluronidase increases tumor uptake of89Zr-DFO-HuMab-5B1 (MVT-2163) in a CA19-9 positive hyaluronan-accumulating pancreatic cancer model
J. Rainey, P. Maffuid, W. Scholz, J. Ostrowski +10 more
2018Tumor Biology1 citations
Semantic Scholar
Abstract 5204: Preclinical development of MVT-1075 as radioimmunotherapy for pancreatic cancer and other CA19-9 positive malignancies
J. Houghton, R. Lanning, Dayla Abdel-atti, To-Ni H. Jun +5 more
20171 citations
Semantic Scholar
Abstract CT026: Phase I trial of HuMab-5B1 (MVT-5873), a novel monoclonal antibody targeting sLea, in patients with advanced pancreatic cancer and other CA19-9 positive malignancies
E. O'Reilly, T. Bauer, J. Infante, J. Gutheil +7 more
20161 citations
Semantic Scholar
Abstract B25: Development of 5B1, an anti-CA19.9 monoclonal antibody, as a near-infrared fluorescent probe for intraoperative imaging of pancreatic cancer
J. Houghton, D. Abdel-Atti, Ritsuko Sawada, W. Scholz +1 more
20151 citations
Semantic Scholar
Cancer Therapy : Preclinical Human Monoclonal Antibodies to Sialyl-Lewisa ( CA 19 . 9 ) with Potent CDC , ADCC , and Antitumor Activity
Ritsuko Sawada, S. Sun, Xiao-Hong Wu, Feng Hong +3 more
20111 citations
Semantic Scholar
Pretargeted 225Ac-radioimmunotherapy of pancreatic ductal adenocarcinoma: evaluating DNA-damage with 89Zr-PET
S. Poty, J. Knight, Komal Mandleywala, Rosemery Membreno +5 more
2019Nuclear Medicine and Biology0 citations
Semantic Scholar
Abstract B104: A therapeutic antibody candidate against the broadly expressed Tn and STn carbohydrate cancer antigens
G. Rainey, Ritsuko Sawada, To-Ni H. Jun, Aleksandra Marinkovic-Petrovic +3 more
20180 citations
Semantic Scholar
Abstract LB-002: A fully human antibody binds Tn and sTn carbohydrate antigens specifically on serine residues, without need for polypeptide interaction
G. Rainey, Ritsuko Sawada, J. Ostrowski, Ayesha Kahn +4 more
2018Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Human antibodies to thomsen-nouvelle (tn) antigen
J. Rainey, W. Scholz, Ritsuko Sawada
20180 citations
Semantic Scholar
Abstract A062: Using CA19-9 as a translational biomarker for sLea targeted agents MVT-5873 and MVT-1075 in cancer
To-Ni H. Jun, C. Lohrmann, V. Allaj, W. Scholz +5 more
20180 citations
Semantic Scholar
Abstract B44: Optimization and IND enabling investigations of MVT-2163 (89Zr-DFO-5B1) leading to First-in-Human readiness
J. Houghton, S. Lyashchenko, Ritsuko Sawada, P. Zanzonico +4 more
20160 citations
Semantic Scholar
Design, synthesis, and in vivo evaluation of novel tetrazine radioligands for the pretargeted PET imaging of PDAC and colorectal cancer
Jan-Philip Meyer, P. Kozlowski, D. Abdel-Atti, J. Houghton +4 more
20160 citations
Semantic Scholar
Abstract 4993: Novel fully human anti-GD2 monoclonal antibodies with potent therapeutic activity against neuroblastoma, sarcoma and melanoma
G. Ragupathi, Xiao-Hong Wu, Ritsuko Sawada, P. Livingston +1 more
20160 citations
Semantic Scholar
Abstract 3051: Improving the efficacy of pretargeted radioimmunotherapy in preclinical murine models by utilizing bioorthogonal click chemistry
J. Houghton, Rosemery Membreno, D. Abdel-Atti, W. Scholz +2 more
20160 citations
Semantic Scholar
Correlative imaging of pancreatic ductal adenocarcinoma over-expressing CA19.9 antigen
N. T. Villegas, S. Carlin, Kuntal K. Sevak, Xiao-Hong Wu +4 more
20130 citations
Semantic Scholar
Abstract C53: Potent CDC, ADCC, and antitumor activity of human monoclonal antibodies to Sialyl Lewisa.
Ritsuko Sawada, Xiao-Hong Wu, S. Sun, G. Ragupathi +2 more
20110 citations
Semantic Scholar
Abstract B122: Human monoclonal antibodies to sialyl‐Lewis‐A with potent CDC and ADCC activity
Ritsuko Sawada, S. Sun, Feng Hong, G. Ragupathi +2 more
20090 citations
Semantic Scholar

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