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G. Ragupathi · SciRah

Researcher profile · Semantic Scholar

G. Ragupathi

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G. Ragupathi — researcher profile on SciRah

h-index: 44
Works: 81
Citations: 4,700

Most-cited papers

Carbohydrate vaccines in cancer: immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man.
S. Slovin, G. Ragupathi, S. Adluri, G. Ungers +11 more
1999Proceedings of the National Academy of Sciences of the United States of America246 citations Open access
Semantic Scholar
Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21.
T. Gilewski, S. Adluri, G. Ragupathi, Shengle Zhang +6 more
2000Clinical Cancer Research211 citations
Semantic Scholar
Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: A phase I trial
T. Gilewski, G. Ragupathi, S. Bhuta, L. J. Williams +10 more
2001Proceedings of the National Academy of Sciences of the United States of America203 citations Open access
Semantic Scholar
Synthetic and Immunological Studies on Clustered Modes of Mucin-Related Tn and TF O-Linked Antigens: The Preparation of a Glycopeptide-Based Vaccine for Clinical Trials against Prostate Cancer†
S. Kuduk, Jacob B. Schwarz, Xiao-Tao Chen, P. Glunz +4 more
1998178 citations
Semantic Scholar
Fully synthetic carbohydrate-based vaccines in biochemically relapsed prostate cancer: clinical trial results with alpha-N-acetylgalactosamine-O-serine/threonine conjugate vaccine.
S. Slovin, G. Ragupathi, C. Musselli, K. Olkiewicz +7 more
2003Journal of Clinical Oncology170 citations
Semantic Scholar
PHASE I TRIAL OF A BIVALENT GANGLIOSIDES VACCINE IN COMBINATION WITH β-GLUCAN
B. Kushner, I. Cheung, S. Modak, K. Kramer +2 more
2014Clinical Cancer Research131 citations Open access
Semantic Scholar
Pilot Study of a Heptavalent Vaccine-Keyhole Limpet Hemocyanin Conjugate plus QS21 in Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer
P. Sabbatini, G. Ragupathi, Chandra Hood, C. Aghajanian +12 more
2007Clinical Cancer Research127 citations
Semantic Scholar
Vaccination of Patients with Small-Cell Lung Cancer with Synthetic Fucosyl GM-1 Conjugated to Keyhole Limpet Hemocyanin
L. Krug, G. Ragupathi, Chandra Hood, M. Kris +9 more
2004Clinical Cancer Research126 citations Open access
Semantic Scholar
Induction of antibodies against GD3 ganglioside in melanoma patients by vaccination with GD3‐lactone‐KLH conjugate plus immunological adjuvant QS‐21
G. Ragupathi, M. Meyers, S. Adluri, L. Howard +2 more
2000International Journal of Cancer126 citations Open access
Semantic Scholar
Vaccination of Small Cell Lung Cancer Patients with Polysialic Acid or N-Propionylated Polysialic Acid Conjugated to Keyhole Limpet Hemocyanin
L. Krug, G. Ragupathi, K. Ng, Chandra Hood +8 more
2004Clinical Cancer Research122 citations
Semantic Scholar
Immunization of ovarian cancer patients with a synthetic Lewisy‐protein conjugate vaccine: A phase 1 trial
P. Sabbatini, V. Kudryashov, G. Ragupathi, S. Danishefsky +11 more
2000International Journal of Cancer119 citations
Semantic Scholar
Comparison of the effect of different immunological adjuvants on the antibody and T-cell response to immunization with MUC1-KLH and GD3-KLH conjugate cancer vaccines.
Soo Kie Kim, G. Ragupathi, C. Musselli, Sun-Ju Choi +2 more
1999Vaccine118 citations
Semantic Scholar
Thomsen-Friedenreich (TF) antigen as a target for prostate cancer vaccine: clinical trial results with TF cluster (c)-KLH plus QS21 conjugate vaccine in patients with biochemically relapsed prostate cancer
S. Slovin, G. Ragupathi, C. Musselli, C. Fernandez +5 more
2005Cancer Immunology and Immunotherapy117 citations Open access
Semantic Scholar
Consistent antibody response against ganglioside GD2 induced in patients with melanoma by a GD2 lactone-keyhole limpet hemocyanin conjugate vaccine plus immunological adjuvant QS-21.
G. Ragupathi, P. Livingston, Chandra Hood, J. Gathuru +6 more
2003Clinical Cancer Research110 citations
Semantic Scholar
Carbohydrate antigens as targets for active specific immunotherapy
G. Ragupathi
1996Cancer Immunology and Immunotherapy109 citations
Semantic Scholar
Antibodies against GD2 ganglioside can eradicate syngeneic cancer micrometastases.
Helen S. Zhang, Sheng-Le Zhang, Nai-Kong V. Cheung, G. Ragupathi +1 more
1998Cancer Research108 citations
Semantic Scholar
Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens.
Shengle Zhang, Helen S. Zhang, C. Cordon-Cardo, G. Ragupathi +1 more
1998Clinical Cancer Research104 citations
Semantic Scholar
Comparison of antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn
E. Kagan, G. Ragupathi, San S. Yi, C. Reis +5 more
2005Cancer Immunology and Immunotherapy99 citations Open access
Semantic Scholar
On the power of chemical synthesis: Immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines
G. Ragupathi, D. M. Coltart, L. J. Williams, F. Koide +6 more
2002Proceedings of the National Academy of Sciences of the United States of America96 citations Open access
Semantic Scholar
Effect of immunological adjuvant combinations on the antibody and T-cell response to vaccination with MUC1-KLH and GD3-KLH conjugates.
Soo Kie Kim, G. Ragupathi, Sarah Cappello, E. Kagan +1 more
2000Vaccine95 citations
Semantic Scholar
Immunogenicity of a fucosyl-GM1-keyhole limpet hemocyanin conjugate vaccine in patients with small cell lung cancer.
M. Dickler, G. Ragupathi, Nancy X. Liu, C. Musselli +6 more
1999Clinical Cancer Research92 citations
Semantic Scholar
Immunization of High-Risk Breast Cancer Patients with Clustered sTn-KLH Conjugate plus the Immunologic Adjuvant QS-21
T. Gilewski, G. Ragupathi, M. Dickler, Shemeeakah Powell +8 more
2007Clinical Cancer Research88 citations Open access
Semantic Scholar
Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma with Prior Disease Progression.
I. Cheung, N. Cheung, S. Modak, A. Mauguen +5 more
2020Journal of Clinical Oncology84 citations Open access
Semantic Scholar
Keyhole limpet hemocyanin conjugate vaccines against cancer: The Memorial Sloan Kettering experience
C. Musselli, P. Livingston, G. Ragupathi
2001Journal of Cancer Research and Clinical Oncology83 citations Open access
Semantic Scholar
A bivalent conjugate vaccine in the treatment of biochemically relapsed prostate cancer: a study of glycosylated MUC-2-KLH and Globo H-KLH conjugate vaccines given with the new semi-synthetic saponin immunological adjuvant GPI-0100 OR QS-21.
S. Slovin, G. Ragupathi, C. Fernandez, M. Jefferson +9 more
2005Vaccine82 citations
Semantic Scholar
A Fully Synthetic Globo H Carbohydrate Vaccine Induces a Focused Humoral Response in Prostate Cancer Patients: A Proof of Principle.
G. Ragupathi, S. Slovin, S. Adluri, D. Sames +8 more
1999Angewandte Chemie80 citations
Semantic Scholar
Reevaluation of the cellular immune response in breast cancer patients vaccinated with MUC1
C. Musselli, G. Ragupathi, T. Gilewski, K. Panageas +2 more
2002International Journal of Cancer75 citations
Semantic Scholar
Immunization of Mice with a Fully Synthetic Globo H Antigen Results in Antibodies against Human Cancer Cells: A Combined Chemical—Immunological Approach to the Fashioning of an Anticancer Vaccine
G. Ragupathi, T. Park, Shengle Zhang, I. Kim +5 more
199775 citations
Semantic Scholar
A polyvalent vaccine for high-risk prostate patients: “are more antigens better?”
S. Slovin, G. Ragupathi, C. Fernandez, M. Diani +8 more
2007Cancer Immunology and Immunotherapy74 citations
Semantic Scholar
Sequential Immunization of Melanoma Patients with GD3 Ganglioside Vaccine and Anti-Idiotypic Monoclonal Antibody That Mimics GD3 Ganglioside
Paul B. Chapman, Dian-Na Y. Wu, G. Ragupathi, Sharon Lu +4 more
2004Clinical Cancer Research74 citations Open access
Semantic Scholar
Vaccines prepared with sialyl-Tn and sialyl-Tn trimers using the 4-(4-maleimidomethyl)cyclohexane-1-carboxyl hydrazide linker group result in optimal antibody titers against ovine submaxillary mucin and sialyl-Tn-positive tumor cells
G. Ragupathi, L. Howard, Sarah Cappello, R. Koganty +5 more
1999Cancer Immunology and Immunotherapy70 citations Open access
Semantic Scholar
Evaluation of Widely Consumed Botanicals as Immunological Adjuvants
G. Ragupathi, K. Yeung, P. Leung, M. Lee +7 more
2008Vaccine69 citations Open access
Semantic Scholar
Human Monoclonal Antibodies to Sialyl-Lewis a (CA19.9) with Potent CDC, ADCC and Anti-Tumor Activity
Ritsuko Sawada, S. Sun, Xiao-Hong Wu, Feng Hong +3 more
2011Clinical Cancer Research66 citations Open access
Semantic Scholar
Tumor cell reactivity mediated by IgM antibodies in sera from melanoma patients vaccinated with GM2 ganglioside covalently linked to KLH is increased by IgG antibodies
Philip S. Livingston, Shengle Zhang, S. Adluri, T. Yao +4 more
1997Cancer Immunology and Immunotherapy65 citations
Semantic Scholar
Biologics through Chemistry: Total Synthesis of a Proposed Dual-Acting Vaccine Targeting Ovarian Cancer by Orchestration of Oligosaccharide and Polypeptide Domains
Jianglong Zhu, Qian Wan, G. Ragupathi, Constantine M George +2 more
2009Journal of the American Chemical Society63 citations Open access
Semantic Scholar
Specificity analysis of sera from breast cancer patients vaccinated with MUC1-KLH plus QS-21
S. Adluri, T. Gilewski, Shengle Zhang, V. Ramnath +2 more
1999British Journal of Cancer63 citations Open access
Semantic Scholar
Imaging Patients with Metastatic Castration-Resistant Prostate Cancer Using 89Zr-DFO-MSTP2109A Anti-STEAP1 Antibody
J. Carrasquillo, B. Fine, N. Pandit-Taskar, S. Larson +13 more
2019Journal of Nuclear Medicine62 citations Open access
Semantic Scholar
Immunization with N-propionyl polysialic acid–KLH conjugate in patients with small cell lung cancer is safe and induces IgM antibodies reactive with SCLC cells and bactericidal against group B meningococci
L. Krug, G. Ragupathi, Chandra Hood, Constantine M George +6 more
2011Cancer Immunology and Immunotherapy59 citations Open access
Semantic Scholar
A preclinical study comparing approaches for augmenting the immunogenicity of a heptavalent KLH-conjugate vaccine against epithelial cancers
G. Ragupathi, F. Koide, N. Sathyan, E. Kagan +7 more
2003Cancer Immunology and Immunotherapy58 citations
Semantic Scholar
Selection of GM2, fucosyl GM1, globo H and polysialic acid as targets on small cell lung cancers for antibody mediated immunotherapy
P. Livingston, Chandra Hood, L. Krug, N. Warren +3 more
2005Cancer Immunology and Immunotherapy56 citations Open access
Semantic Scholar
Comparison of antibody titers after immunization with monovalent or tetravalent KLH conjugate vaccines.
G. Ragupathi, Sarah Cappello, San S. Yi, D. Canter +4 more
2002Vaccine51 citations
Semantic Scholar
Immunogenicity of synthetic conjugates of Lewisy oligosaccharide with proteins in mice: towards the design of anticancer vaccines
V. Kudryashov, Hyunjin Kim, G. Ragupathi, S. Danishefsky +2 more
1998Cancer Immunology and Immunotherapy50 citations
Semantic Scholar
A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission
R. O'Cearbhaill, G. Ragupathi, Jianglong Zhu, Qian Wan +9 more
2016Cancers48 citations Open access
Semantic Scholar
A novel and efficient method for synthetic carbohydrate conjugate vaccine preparation: synthesis of sialyl Tn-KLH conjugate using a 4-(4-N-maleimidomethyl) cyclohexane-1-carboxyl hydrazide (MMCCH) linker arm
G. Ragupathi, R. Koganty, D. Qiu, K. Lloyd +1 more
1998Glycoconjugate Journal46 citations
Semantic Scholar
Preclinical Evaluation of the Synthetic Adjuvant SQS-21 and its Constituent Isomeric Saponins
G. Ragupathi, Payal Damani, K. Deng, M. Adams +4 more
2010Vaccine41 citations Open access
Semantic Scholar
Strategy in Oligosaccharide Synthesis: An Application to a Concise Total Synthesis of the KH-1(adenocarcinoma) Antigen
P. Deshpande, Hyunjin M. Kim, A. Zatorski, T. Park +4 more
199839 citations
Semantic Scholar
Synthesis of selected LeY and KH-1 analogues: a medicinal chemistry approach to vaccine optimization.
M. Spassova, W. Bornmann, G. Ragupathi, G. Sukenick +2 more
2005Journal of Organic Chemistry33 citations
Semantic Scholar
Autoimmune and Antitumor Consequences of Antibodies Against Antigens Shared by Normal and Malignant Tissues
P. Livingston, G. Ragupathi, C. Musselli
2000Journal of Clinical Immunology31 citations
Semantic Scholar
Pharmacokinetics and Biodistribution of [89Zr]Zr-DFO-MSTP2109A Anti-STEAP1 Antibody in Metastatic Castration-Resistant Prostate Cancer Patients
J. O'Donoghue, D. Danila, N. Pandit-Taskar, V. Beylergil +14 more
2019Molecular Pharmaceutics30 citations Open access
Semantic Scholar
Constructing an adenocarcinoma vaccine: Immunization of mice with synthetic KH‐1 nonasaccharide stimulates anti‐KH‐1 and anti‐Ley antibodies
G. Ragupathi, P. Deshpande, D. M. Coltart, Hyunjin Kim +3 more
2002International Journal of Cancer28 citations Open access
Semantic Scholar

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T. Gilewski — researcher profile on SciRah