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Y. Tomabechi · SciRah

Researcher profile · Semantic Scholar

Y. Tomabechi

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Y. Tomabechi — researcher profile on SciRah

h-index: 17
Works: 56
Citations: 733

Most-cited papers

A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Y. Saito, H. Yuki, M. Kuratani, Yoshinobu Hashizume +25 more
2013Science Translational Medicine85 citations
Semantic Scholar
Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modes.
Kazue Terasawa, Y. Tomabechi, Mariko Ikeda, H. Ehara +7 more
2016Biochemical and Biophysical Research Communications - BBRC70 citations
Semantic Scholar
Structural basis for CRMP2-induced axonal microtubule formation
Shinsuke Niwa, F. Nakamura, Y. Tomabechi, M. Aoki +8 more
2017Scientific Reports54 citations Open access
Semantic Scholar
Crystal structure of nanoKAZ: The mutated 19 kDa component of Oplophorus luciferase catalyzing the bioluminescent reaction with coelenterazine.
Y. Tomabechi, T. Hosoya, H. Ehara, S. Sekine +2 more
2016Biochemical and Biophysical Research Communications - BBRC42 citations
Semantic Scholar
A reproducible and scalable procedure for preparing bacterial extracts for cell-free protein synthesis
Kazushige Katsura, T. Matsuda, Y. Tomabechi, Mayumi Yonemochi +5 more
2017Journal of Biochemistry (Tokyo)41 citations Open access
Semantic Scholar
Crystal Structure of the Ca2+/Calmodulin-dependent Protein Kinase Kinase in Complex with the Inhibitor STO-609*
M. Kukimoto-Niino, S. Yoshikawa, T. Takagi, N. Ohsawa +11 more
2011Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of Sam68.
E. Morishita, K. Murayama, M. Kato-Murayama, Y. Ishizuka-Katsura +7 more
2011Structure37 citations Open access
Semantic Scholar
Protein stabilization utilizing a redefined codon
Kazumasa Ohtake, A. Yamaguchi, T. Mukai, H. Kashimura +13 more
2015Scientific Reports35 citations Open access
Semantic Scholar
A novel Pim-1 kinase inhibitor targeting residues that bind the substrate peptide.
K. Tsuganezawa, Hisami Watanabe, L. Parker, H. Yuki +13 more
2012Journal of Molecular Biology30 citations
Semantic Scholar
CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation
T. Imasaki, Satoshi Kikkawa, Shinsuke Niwa, Yumiko Saijo-Hamano +16 more
2022eLife26 citations Open access
Semantic Scholar
Chemical reversal of abnormalities in cells carrying mitochondrial DNA mutations
Hiroki Kobayashi, Hideyuki Hatakeyama, Haruna Nishimura, Mutsumi Yokota +7 more
2020Nature Chemical Biology25 citations Open access
Semantic Scholar
Amyloid conformation-dependent disaggregation in a reconstituted yeast prion system
Y. Nakagawa, Howard C.-H. Shen, Yusuke Komi, Shinju Sugiyama +12 more
2022Nature Chemical Biology24 citations Open access
Semantic Scholar
Structures of histone methyltransferase SET7/9 in complexes with adenosylmethionine derivatives.
H. Niwa, N. Handa, Y. Tomabechi, K. Honda +7 more
2013Acta Crystallographica Section D: Biological Crystallography23 citations
Semantic Scholar
Solution structure of the RNA binding domain in the human muscleblind‐like protein 2
F. He, W. Dang, C. Abe, K. Tsuda +16 more
2009Protein Science23 citations Open access
Semantic Scholar
Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells
Kazue Terasawa, Yuji Kato, Y. Ikami, K. Sakamoto +11 more
2021Autophagy19 citations Open access
Semantic Scholar
POLArIS, a versatile probe for molecular orientation, revealed actin filaments associated with microtubule asters in early embryos
Ayana Sugizaki, Keisuke Sato, K. Chiba, Kenta Saito +8 more
2020Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
Crystal structures of the S6K1 kinase domain in complexes with inhibitors
H. Niwa, J. Mikuni, Shunta Sasaki, Y. Tomabechi +9 more
2014Journal of Structural and Functional Genomics17 citations Open access
Semantic Scholar
Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor.
L. Parker, Hisami Watanabe, K. Tsuganezawa, Y. Tomabechi +8 more
2012Acta Crystallographica. Section F : Structural Biology and Crystallization Communications16 citations Open access
Semantic Scholar
Reverse mutants of the catalytic 19 kDa mutant protein (nanoKAZ/nanoLuc) from Oplophorus luciferase with coelenterazine as preferred substrate
S. Inouye, J. Sato, Yuiko Sahara-Miura, Y. Tomabechi +4 more
2022PLoS ONE12 citations Open access
Semantic Scholar
The NF‐κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2‐catalysed reaction
Shisako Shoji, Kazuharu Hanada, Masataka Takahashi, Kazuhide Watanabe +3 more
2020FEBS Letters12 citations Open access
Semantic Scholar
Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models
M. Takeshita, H. Fukuyama, K. Kamada, Takehisa Matsumoto +27 more
2022iScience10 citations Open access
Semantic Scholar
Phosphorylated and non-phosphorylated HCK kinase domains produced by cell-free protein expression.
Kazushige Katsura, Y. Tomabechi, T. Matsuda, Mayumi Yonemochi +7 more
2018Protein Expression and Purification10 citations
Semantic Scholar
Identification of pyrrolo[2,3-d]pyrimidines as potent HCK and FLT3-ITD dual inhibitors.
Y. Koda, Ko Kikuzato, J. Mikuni, A. Tanaka +7 more
2017Bioorganic & Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
Chiral deaza-coelenterazine analogs for probing a substrate-binding site in the Ca2+-binding photoprotein aequorin
S. Inouye, Yuto Sumida, Y. Tomabechi, Jumpei Taguchi +2 more
2021PLoS ONE9 citations Open access
Semantic Scholar
Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
L. Parker, Shigenao Taruya, K. Tsuganezawa, Naoko Ogawa +7 more
2014Acta Crystallographica Section D: Biological Crystallography9 citations
Semantic Scholar
Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
H. Yuki, Ko Kikuzato, Y. Koda, J. Mikuni +7 more
2017Bioorganic & Medicinal Chemistry8 citations Open access
Semantic Scholar
CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre
T. Imasaki, S. Kikkawa, Shinsuke Niwa, Y. Saijo-Hamano +16 more
2021bioRxiv7 citations Open access
Semantic Scholar
The luciferase-based in vivo protein–protein interaction assay revealed that CHK1 promotes PP2A and PME-1 interaction
Sana Ando, Keiko Tanaka, Maharu Matsumoto, Yuki Oyama +8 more
2024Journal of Biological Chemistry5 citations Open access
Semantic Scholar
Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of cf3-aequorin
S. Inouye, Y. Tomabechi, T. Hosoya, S. Sekine +1 more
2018Journal of Biochemistry (Tokyo)5 citations
Semantic Scholar
PLA2G12A-driven extracellular vesicle-lipid signaling amplifies pathogenic T cell responses in inflammatory diseases.
Chika Mochizuki-Ono, Y. Taketomi, Atsushi Irie, K. Kano +18 more
2026Cell Reports4 citations Open access
Semantic Scholar
Structural insight into bacterial co-transcriptional translation initiation
T. Yokoyama, Yuko Murayama, Tomomi Uchikubo-Kamo, Y. Tomabechi +4 more
2024bioRxiv4 citations Open access
Semantic Scholar
Crystal Structure of an Archaeal Tyrosyl-tRNA Synthetase Bound to Photocaged L-Tyrosine and Its Potential Application to Time-Resolved X-ray Crystallography
T. Hosaka, Kazushige Katsura, Y. Ishizuka-Katsura, Kazuharu Hanada +6 more
2022International Journal of Molecular Sciences3 citations Open access
Semantic Scholar
Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents
M. Takeshita, H. Fukuyama, K. Kamada, Takehisa Matsumoto +25 more
2023iScience2 citations Open access
Semantic Scholar
Secreted phospholipase PLA2G12A-driven lysophospholipid signaling via lipolytic modification of extracellular vesicles facilitates pathogenic Th17 differentiation
Chika Mochizuki, Y. Taketomi, A. Irie, K. Kano +18 more
2024bioRxiv1 citations
Semantic Scholar
Switching of the c-Myc protein degradation pathway depending on the PP2A-B55α complex levels
Sana Ando, Shunta Ikeda, Keiko Tanaka, Y. Tomabechi +7 more
2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
Fc-modified SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models
M. Takeshita, H. Fukuyama, K. Kamada, Takehisa Matsumoto +27 more
2022bioRxiv0 citations Open access
Semantic Scholar
Crystal structure of POLArISact(T57S), genetically encoded probe for fluorescent polarization
Y. Tomabechi, N. Sakai, M. Shirouzu
20210 citations
Semantic Scholar
Crystal structure of the apoAequorin complex with (S)-daCTZ
Y. Tomabechi, M. Shirouzu
20210 citations
Semantic Scholar
Crystal structure of the apoAequorin complex with (S)-HM-daCTZ
Y. Tomabechi, M. Shirouzu
20210 citations
Semantic Scholar
Amyloid conformation-dependent disaggregation revealed by a reconstituted yeast prion system
Motomasa Tanaka, Y. Nakagawa, Howard C.-H. Shen, Shinju Sugiyama +10 more
20200 citations Open access
Semantic Scholar
Crystal structure of cf3 -aequorin: a semi-synthetic aequorin with long half-decay time of luminescence
Y. Tomabechi, S. Inouye, T. Hosoya, S. Sekine +1 more
20180 citations
Semantic Scholar
Crystal structure of cf3-aequorin
S. Inouye, Y. Tomabechi, S. Sekine, M. Shirouzu +1 more
20180 citations
Semantic Scholar
Crystal Structure of Human CRMP-2
R. Nitta, Y. Tomabechi, M. Aoki, M. Shirouzu
20170 citations
Semantic Scholar
Crystal Structure of T246A-N247A Human CRMP-2 Mutant
R. Nitta, Y. Tomabechi, M. Aoki, M. Shirouzu
20170 citations
Semantic Scholar
Structural basis for CRMP2-induced axonal microtubule formation
Shinsuke Niwa, F. Nakamura, Y. Tomabechi, M. Aoki +8 more
2017Scientific Reports0 citations Open access
Semantic Scholar
Scalable method for preparation of bacterial extract for cell-free protein synthesis
Kazushige Katsura, Y. Tomabechi, T. Matsuda, Mayumi Yonemochi +5 more
20160 citations
Semantic Scholar
Crystal structure of Pim1 in complex with the inhibitor Quercetin (resulting from displacement of SKF86002)
L. Parker, A. Tanaka, N. Handa, K. Honda +3 more
20140 citations
Semantic Scholar
Crystal Structure of Pim-1 in complex with the fluorescent compound SKF86002
L. Parker, A. Tanaka, N. Handa, K. Honda +3 more
20140 citations
Semantic Scholar
Crystal Structure of HCK in complex with 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (resulting from displacement of SKF86002)
L. Parker, A. Tanaka, N. Handa, K. Honda +3 more
20140 citations
Semantic Scholar
Crystal structure of Pim1 in complex with 2-{4-[(3-aminopropyl)amino]quinazolin-2-yl}phenol (resulting from displacement of SKF86002)
L. Parker, A. Tanaka, N. Handa, K. Honda +3 more
20140 citations
Semantic Scholar

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