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S. Ren · SciRah

Researcher profile · Semantic Scholar

S. Ren

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S. Ren — researcher profile on SciRah

h-index: 25
Works: 34
Citations: 3,110

Most-cited papers

MicroRNA 21 promotes fibrosis of the kidney by silencing metabolic pathways
B. Chau, C. Xin, Jochen C. Hartner, S. Ren +14 more
2012Science Translational Medicine579 citations Open access
Semantic Scholar
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Ivan G. Gomez, D. Mackenna, B. Johnson, V. Kaimal +16 more
2015Journal of Clinical Investigation386 citations Open access
Semantic Scholar
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1
S. Ren, B. Johnson, Y. Kida, Colin Ip +7 more
2013Proceedings of the National Academy of Sciences of the United States of America200 citations Open access
Semantic Scholar
Wnt signalling in kidney diseases: dual roles in renal injury and repair
Takahisa Kawakami, S. Ren, J. S. Duffield
2013Journal of Pathology195 citations Open access
Semantic Scholar
Sphingosine 1-Phosphate Cross-activates the Smad Signaling Cascade and Mimics Transforming Growth Factor-β-induced Cell Responses*
C. Xin, S. Ren, B. Kleuser, Soheyla Shabahang +5 more
2004Journal of Biological Chemistry194 citations Open access
Semantic Scholar
Metchnikoff’s Policemen—Macrophages in Development, Homeostasis and Regeneration
James A. Stefater, S. Ren, R. Lang, J. Duffield
2011Trends in Molecular Medicine180 citations Open access
Semantic Scholar
Anti-Proteinase 3 Anti-Neutrophil Cytoplasm Autoantibodies Recapitulate Systemic Vasculitis in Mice with a Humanized Immune System
M. Little, B. Al-Ani, S. Ren, H. Al-Nuaimi +4 more
2012PLoS ONE173 citations Open access
Semantic Scholar
Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS.
Takahisa Kawakami, Ivan G. Gomez, S. Ren, K. Hudkins +5 more
2015Journal of the American Society of Nephrology163 citations Open access
Semantic Scholar
A Novel Three-Dimensional Human Peritubular Microvascular System.
G. Ligresti, Ryan J. Nagao, Jun Xue, Yoon Jung Choi +11 more
2016Journal of the American Society of Nephrology81 citations Open access
Semantic Scholar
Biotransformation of d-Limonene to (+)trans-Carveol by Toluene-Grown Rhodococcus opacusPWD4 Cells
W. Duetz, Ann H. M. Fjällman, S. Ren, Catherine Jourdat +1 more
2001Applied and Environmental Microbiology76 citations Open access
Semantic Scholar
Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression.
S. Ren, A. Babelova, K. Moreth, C. Xin +6 more
2009Kidney International74 citations Open access
Semantic Scholar
Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease.
Guo-Chun Chen, Huihui Chen, S. Ren, Ming Xia +7 more
2019Kidney International72 citations Open access
Semantic Scholar
The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells
C. Xin, S. Ren, W. Eberhardt, J. Pfeilschifter +1 more
2006British Journal of Pharmacology70 citations Open access
Semantic Scholar
Cysteamine modulates oxidative stress and blocks myofibroblast activity in CKD.
D. Okamura, Nadia M. Bahrami, S. Ren, K. Pasichnyk +7 more
2014Journal of the American Society of Nephrology69 citations Open access
Semantic Scholar
A Novel Mode of Action of the Putative Sphingosine Kinase Inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) Thiazole (SKI II): Induction of Lysosomal Sphingosine Kinase 1 Degradation
S. Ren, C. Xin, J. Pfeilschifter, A. Huwiler
2010Cellular Physiology and Biochemistry67 citations Open access
Semantic Scholar
Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y2 purinoceptor in renal mesangial cells
A. Huwiler, Waltraud Rölz, S. Dorsch, S. Ren +1 more
2002British Journal of Pharmacology64 citations Open access
Semantic Scholar
Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism.
A. Huwiler, Frauke Döll, S. Ren, Sabine Klawitter +5 more
2006Biochimica et Biophysica Acta59 citations
Semantic Scholar
Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner
L. P. Hofmann, S. Ren, S. Schwalm, J. Pfeilschifter +1 more
2008Biological chemistry57 citations Open access
Semantic Scholar
Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis
N. Nakagawa, C. Xin, A. Roach, Natalie Naiman +6 more
2015Kidney International56 citations Open access
Semantic Scholar
PPARalpha activation upregulates nephrin expression in human embryonic kidney epithelial cells and podocytes by a dual mechanism.
S. Ren, C. Xin, K. Beck, M. Saleem +4 more
2005Biochemical and Biophysical Research Communications - BBRC45 citations
Semantic Scholar
Pericytes in kidney fibrosis
S. Ren, J. Duffield
2013Current opinion in nephrology and hypertension38 citations
Semantic Scholar
Inflammatory cytokines upregulate nephrin expression in human embryonic kidney epithelial cells and podocytes.
A. Huwiler, S. Ren, H. Holthöfer, H. Pavenstädt +1 more
2003Biochemical and Biophysical Research Communications - BBRC37 citations
Semantic Scholar
Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor-Related Protein 6.
B. Johnson, S. Ren, G. Karaca, Ivan G. Gomez +8 more
2017Journal of the American Society of Nephrology33 citations Open access
Semantic Scholar
Hyperactive FOXO1 results in lack of tip stalk identity and deficient microvascular regeneration during kidney injury
Lan T. H. Dang, T. Aburatani, G. Marsh, B. Johnson +14 more
2017Biomaterials28 citations Open access
Semantic Scholar
Heterologous desensitization of the sphingosine‐1‐phosphate receptors by purinoceptor activation in renal mesangial cells
C. Xin, S. Ren, J. Pfeilschifter, A. Huwiler
2004British Journal of Pharmacology27 citations Open access
Semantic Scholar
Nephrin expression is increased in anti-Thy1.1-induced glomerulonephritis in rats.
L. Schaefer, S. Ren, R. Schaefer, D. Mihálik +3 more
2004Biochemical and Biophysical Research Communications - BBRC24 citations
Semantic Scholar
FTY720 suppresses interleukin‐1β‐induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism
C. Xin, S. Ren, W. Eberhardt, J. Pfeilschifter +1 more
2007British Journal of Pharmacology18 citations Open access
Semantic Scholar
Interleukin-1 inhibits angiotensin II-stimulated protein kinase B pathway in renal mesangial cells via the inducible nitric oxide synthase.
W. Rölz, C. Xin, S. Ren, J. Pfeilschifter +1 more
2002European Journal of Pharmacology11 citations
Semantic Scholar
Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1β-induced prostaglandin E2 formation Published, JLR Papers in Press, June 25, 2007.
C. Xin, S. Ren, W. Eberhardt, J. Pfeilschifter +1 more
2007Journal of Lipid Research10 citations Open access
Semantic Scholar
CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Voriconazole in Chinese Kidney Transplant Patients
Yundi Zhang, Yue Du, S. Ren, Yue Li +5 more
2023The Annals of Pharmacotherapy8 citations Open access
Semantic Scholar
Association between GLP-1R gene polymorphism and dyslipidemia in Chinese patients with type 2 diabetes mellitus: a case-control study.
Yue Li, Zhi-Yan Yang, S. Ren, Bowen Shen +3 more
2023Gene7 citations Open access
Semantic Scholar
Interleukin‐1β inhibits ATP‐induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide
W. Rölz, C. Xin, S. Ren, J. Pfeilschifter +1 more
2003British Journal of Pharmacology7 citations Open access
Semantic Scholar
Correction for Ren et al., LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1
S. Ren, B. Johnson, Yujiro, Kida +8 more
2016Proceedings of the National Academy of Sciences of the United States of America2 citations Open access
Semantic Scholar
SK-1基因敲除联合阿霉素抑制乳腺癌细胞MDA-MB-231的增殖和迁移
Xu Xu, S. Ren, C. Xin
20090 citations
Semantic Scholar

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J. Pfeilschifter×15
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A. Huwiler×15
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C. Xin×14
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Ivan G. Gomez — researcher profile on SciRah

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R. Lang — researcher profile on SciRah

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