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Haihong Shen · SciRah

Researcher profile · Semantic Scholar

Haihong Shen

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Haihong Shen — researcher profile on SciRah

h-index: 25
Works: 75
Citations: 2,760

Most-cited papers

Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene.
C. Ghigna, S. Giordano, Haihong Shen, F. Benvenuto +5 more
2005Molecules and Cells401 citations Open access
Semantic Scholar
Arginine-serine-rich domains bound at splicing enhancers contact the branchpoint to promote prespliceosome assembly.
Haihong Shen, Julie L. C. Kan, Michael R. Green
2004Molecules and Cells276 citations Open access
Semantic Scholar
A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly.
Haihong Shen, Michael R. Green
2004Molecules and Cells231 citations Open access
Semantic Scholar
Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.
E. Sickmier, Katherine E. Frato, Haihong Shen, Shanthi R. Paranawithana +2 more
2006Molecules and Cells193 citations Open access
Semantic Scholar
RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans.
Haihong Shen, Michael R. Green
2006Genes & Development146 citations Open access
Semantic Scholar
A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications
Su-Juan Guo, Yan-Ping Liang, Susan Murphy, Angela Huang +4 more
2015Autophagy134 citations Open access
Semantic Scholar
The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing.
Haihong Shen, Xuexiu Zheng, Stephan Luecke, Michael R. Green
2010Genes & Development106 citations Open access
Semantic Scholar
Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome.
Haihong Shen, Xuexiu Zheng, Jing-Ping Shen, Ling-Di Zhang +2 more
2008Genes & Development96 citations Open access
Semantic Scholar
CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer.
T. Loh, Heegyum Moon, Sunghee Cho, H. Jang +11 more
2015Oncology Report75 citations Open access
Semantic Scholar
A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2.
Haihong Shen, Julie L. C. Kan, C. Ghigna, G. Biamonti +1 more
2004RNA: A publication of the RNA Society68 citations Open access
Semantic Scholar
UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export.
Haihong Shen
2009BMB Reports61 citations Open access
Semantic Scholar
Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m6A Methylation of RNA in Acute Myeloid Leukemia Cells
Je-Heon Lee, Namjeong Choi, Subin Kim, Mi-Sun Jin +2 more
2022Pharmaceuticals56 citations Open access
Semantic Scholar
RS domain–splicing signal interactions in splicing of U12-type and U2-type introns
Haihong Shen, Michael R. Green
2007Nature Structural &Molecular Biology56 citations
Semantic Scholar
Splicing inhibition of U2AF65 leads to alternative exon skipping
Sunghee Cho, Heegyum Moon, T. Loh, H. Jang +5 more
2015Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7.
Sunghee Cho, Heegyum Moon, T. Loh, Huyn Kyung Oh +6 more
2014Biochimica et Biophysica Acta45 citations
Semantic Scholar
hnRNP A1 contacts exon 5 to promote exon 6 inclusion of apoptotic Fas gene
H. Oh, Eunkyung Lee, H. Jang, Jaehoon Lee +9 more
2013Apoptosis34 citations Open access
Semantic Scholar
Exon 9 skipping of apoptotic caspase-2 pre-mRNA is promoted by SRp20 through interaction with exon 8
H. Jang, Min‐Hyo Lee, T. Loh, Seungho Choi +10 more
2013Biochimica et Biophysica Acta34 citations Open access
Semantic Scholar
Solution Conformation and Thermodynamic Characteristics of RNA Binding by the Splicing Factor U2AF65*
J. Jenkins, Haihong Shen, Michael R. Green, C. Kielkopf
2008Journal of Biological Chemistry32 citations Open access
Semantic Scholar
PSF contacts exon 7 of SMN2 pre-mRNA to promote exon 7 inclusion
Sunghee Cho, Heegyum Moon, T. Loh, H. Oh +6 more
2014Biochimica et Biophysica Acta31 citations Open access
Semantic Scholar
Detecting RNA-Protein Interaction Using End-Labeled Biotinylated RNA Oligonucleotides and Immunoblotting.
Xuexiu Zheng, Sunghee Cho, Heegyum Moon, T. Loh +2 more
2016Methods in molecular biology30 citations
Semantic Scholar
Possible Formation of Mitochondrial-RNA Containing Chimeric or Trimeric RNA Implies a Post-Transcriptional and Post-Splicing Mechanism for RNA Fusion
Wei Yang, Jian-Min Wu, An-Ding Bi, Yong-chang Ou-yang +6 more
2013PLoS ONE29 citations Open access
Semantic Scholar
CRISPR as a strong gene editing tool
Shengfu Shen, T. Loh, Hong-Ling Shen, Xuexiu Zheng +1 more
2017BMB Reports27 citations Open access
Semantic Scholar
Targeting RNA-splicing for SMA treatment
Jian-Hua Zhou, Xuexiu Zheng, Haihong Shen
2012Molecules and Cells26 citations Open access
Semantic Scholar
SRSF2 promotes splicing and transcription of exon 11 included isoform in Ron proto-oncogene
Heegyum Moon, Sunghee Cho, T. Loh, H. Oh +11 more
2014Biochimica et Biophysica Acta25 citations Open access
Semantic Scholar
Differential physiological roles of ESCRT complexes in Caenorhabditis elegans
Dong-Wan Kim, Hyun Sung, D. Shin, Haihong Shen +3 more
2011Molecules and Cells25 citations Open access
Semantic Scholar
Delineation of the role of glycosylation in the cytotoxic properties of quercetin using novel assays in living vertebrates.
Si-Hwan Park, H. Kim, Soon-Ho Yim, A. Kim +6 more
2014Journal of Natural Products24 citations
Semantic Scholar
hnRNP A1 Regulates Alternative Splicing of Tau Exon 10 by Targeting 3′ Splice Sites
Yongchao Liu, Donggun Kim, Namjeong Choi, Jagyeong Oh +4 more
2020Cells23 citations Open access
Semantic Scholar
Irf3 Polymorphism Alters Induction of Interferon Beta in Response to Listeria monocytogenes Infection
O. Garifulin, Zan-Mei Qi, Haihong Shen, Sujatha Patnala +2 more
2007PLoS Genetics23 citations Open access
Semantic Scholar
hnRNP L inhibits CD44 V10 exon splicing through interacting with its upstream intron.
T. Loh, Sunghee Cho, Heegyum Moon, H. Jang +7 more
2015Biochimica et Biophysica Acta22 citations
Semantic Scholar
Isoforms of wild type proteins often appear as low molecular weight bands on SDS‐PAGE
Ju Zhang, Xiaomin Lou, Haihong Shen, Lucas Zellmer +4 more
2014Biotechnology Journal22 citations
Semantic Scholar
SC35 promotes splicing of the C5-V6-C6 isoform of CD44 pre-mRNA
T. Loh, Heegyum Moon, Sunghee Cho, Da-Woon Jung +6 more
2013Oncology Report20 citations Open access
Semantic Scholar
SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon
Jiyeon Ha, H. Jang, Namjeong Choi, Jagyeong Oh +8 more
2021Cells18 citations Open access
Semantic Scholar
Widespread Alternative Splicing Changes in Metastatic Breast Cancer Cells
Jagyeong Oh, D. Pradella, Changwei Shao, Hai-Ri Li +7 more
2021Cells18 citations Open access
Semantic Scholar
Apoptosis in Living Animals Is Assisted by Scavenger Cells and Thus May Not Mainly Go through the Cytochrome C-Caspase Pathway
Bingya Liu, Ning-Zhi Xu, Yan-gao Man, Haihong Shen +3 more
2013Journal of Cancer18 citations Open access
Semantic Scholar
Chimeric RNAs as potential biomarkers for tumor diagnosis.
Jian-Hua Zhou, Joshua Liao, Xuexiu Zheng, Haihong Shen
2012BMB Reports18 citations Open access
Semantic Scholar
SRSF6 Regulates the Alternative Splicing of the Apoptotic Fas Gene by Targeting a Novel RNA Sequence
Namjeong Choi, H. Jang, Jagyeong Oh, Jiyeon Ha +4 more
2022Cancers17 citations Open access
Semantic Scholar
Some leopards can change their spots: potential repositioning of stem cell reprogramming compounds as anti-cancer agents
Woong-Hee Kim, Haihong Shen, Da-Woon Jung, D. Williams
2016Cell Biology and Toxicology16 citations Open access
Semantic Scholar
Identification of a novel cis-element that regulates alternative splicing of Bcl-x pre-mRNA.
Jaehoon Lee, Jian-Hua Zhou, Xuexiu Zheng, Sunghee Cho +4 more
2012Biochemical and Biophysical Research Communications - BBRC16 citations
Semantic Scholar
A SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy Model
Ye Seul Son, Kwangman Choi, Hana Lee, Ohman Kwon +17 more
2019Stem Cells and Development15 citations
Semantic Scholar
SRSF2 directly inhibits intron splicing to suppresses cassette exon inclusion
Heegyum Moon, Sunghee Cho, T. Loh, H. Jang +10 more
2017BMB Reports15 citations Open access
Semantic Scholar
Binding of SRSF4 to a novel enhancer modulates splicing of exon 6 of Fas pre-mRNA.
H. Jang, Yongchao Liu, Namjeong Choi, Jagyeong Oh +3 more
2018Biochemical and Biophysical Research Communications - BBRC13 citations
Semantic Scholar
SR proteins regulate V6 exon splicing of CD44 pre-mRNA
T. Loh, Heegyum Moon, H. Jang, Yongchao Liu +6 more
2016BMB Reports12 citations Open access
Semantic Scholar
Two Site Contact of Elongating Transcripts to Phage T7 RNA Polymerase at C-terminal Regions*
Haihong Shen, Changwon Kang
2000Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Global Alternative Splicing Defects in Human Breast Cancer Cells
Jagyeong Oh, D. Pradella, Yoon-Dong Kim, Changwei Shao +8 more
2021Cancers11 citations Open access
Semantic Scholar
Opposite Roles of Tra2β and SRSF9 in the v10 Exon Splicing of CD44
Jagyeong Oh, Yongchao Liu, Namjeong Choi, Jiyeon Ha +4 more
2020Cancers11 citations Open access
Semantic Scholar
Activation of Cryptic 3′ Splice-Sites by SRSF2 Contributes to Cassette Exon Skipping
Heegyum Moon, H. Jang, Yongchao Liu, Namjeong Choi +4 more
2019Cells11 citations Open access
Semantic Scholar
Disruption of endocytic pathway regulatory genes activates autophagy in C. elegans
Meenakshi Dwivedi, Hyun Sung, Haihong Shen, B. Park +1 more
2011Molecules and Cells11 citations Open access
Semantic Scholar
U2AF65-Dependent SF3B1 Function in SMN Alternative Splicing
Namjeong Choi, Yongchao Liu, Jagyeong Oh, Jiyeon Ha +2 more
2020Cells10 citations Open access
Semantic Scholar
Effects of PTCs on nonsense-mediated mRNA decay are dependent on PTC location.
Heegyum Moon, Xuexiu Zheng, T. Loh, H. Jang +4 more
2017Oncology Letters9 citations Open access
Semantic Scholar
Validation of trans-acting elements that promote exon 7 skipping of SMN2 in SMN2-GFP stable cell line.
Sunghee Cho, Heegyum Moon, Xiao-Ming Yang, Jian-Hua Zhou +5 more
2012Biochemical and Biophysical Research Communications - BBRC9 citations
Semantic Scholar

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