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M. Tsai · SciRah

Researcher profile · Semantic Scholar

M. Tsai

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M. Tsai — researcher profile on SciRah

h-index: 47
Works: 327
Citations: 8,502

Most-cited papers

The Regulatory Mechanisms of Tumor Suppressor P16INK4A and Relevance to Cancer
Ju-Nan Li, M. Poi, M. Tsai
2011Biochemistry320 citations Open access
Semantic Scholar
Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease
Pei-Chi Wei, Yi-Hsuan Hsieh, M. Su, Xianzhi Jiang +11 more
2012Molecules and Cells150 citations Open access
Semantic Scholar
Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.
Yu-Ching Teng, Cheng-Feng Lee, Ying-Shiuan Li, Yi-ren Chen +10 more
2013Cancer Research148 citations
Semantic Scholar
A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi
Hsin-Yue Tsai, Chun-Chieh G. Chen, D. Conte, James J. Moresco +5 more
2015Cell99 citations Open access
Semantic Scholar
How DNA polymerases catalyse replication and repair with contrasting fidelity
Wen-Jin Wu, Wei Yang, M. Tsai
201770 citations
Semantic Scholar
Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response
Yung-Lin Hsieh, Hong-Yi Kuo, Che-Chang Chang, M. Naik +8 more
2013EMBO Journal68 citations Open access
Semantic Scholar
Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii
S. Franz, E. Ignatz, S. Wenzel, H. Zielosko +6 more
2018Nucleic Acids Research65 citations Open access
Semantic Scholar
Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFA.
T. Wei, Pei-Yu Wu, Ting-Jung Wu, H. Hou +11 more
2017Cancer Research63 citations
Semantic Scholar
Fha Interaction with Phosphothreonine of TssL Activates Type VI Secretion in Agrobacterium tumefaciens
Jer-Sheng Lin, Hsin-Hui Wu, Pang-Hung Hsu, Lay-Sun Ma +3 more
2014PLoS Pathogens59 citations Open access
Semantic Scholar
Intermolecular Binding between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF-κB Activation
C. Huang, J. Weng, T. Wei, Pei-Yu Wu +9 more
2012Molecular and Cellular Biology54 citations Open access
Semantic Scholar
TIFA as a crucial mediator for NLRP3 inflammasome
Ting Lin, T. Wei, Shuai Li, Shen-Chih Wang +11 more
2016Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
Semantic Scholar
STRENDA DB: enabling the validation and sharing of enzyme kinetics data
Neil Swainston, A. Baici, Barbara M. Bakker, A. Cornish-Bowden +15 more
2018The FEBS Journal49 citations Open access
Semantic Scholar
Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme
M. Maestre-Reyna, Cheng-Han Yang, E. Nango, Wei-Cheng Huang +34 more
2022Nature Chemistry47 citations Open access
Semantic Scholar
Reversible Acetylation Regulates Salt-inducible Kinase (SIK2) and Its Function in Autophagy*
Fu-Chia Yang, B. Tan, Wei-Hao Chen, Ya-Huei Lin +10 more
2013Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Chin-Yuan Chang, Syue-Yi Lyu, Yu‐Chen Liu, Ning-Shian Hsu +7 more
2014Angewandte Chemie46 citations
Semantic Scholar
Amino Acid Substitutions of MagA in Klebsiella pneumoniae Affect the Biosynthesis of the Capsular Polysaccharide
Tzu-Lung Lin, Feng-Ling Yang, An-Suei Yang, Hung-Pin Peng +4 more
2012PLoS ONE46 citations Open access
Semantic Scholar
The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation
Tsung-Chieh Lin, Chia-Yi Su, Pei-Yu Wu, T. Lai +14 more
2016eLife44 citations Open access
Semantic Scholar
Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses.
J. Weng, Y. Hsieh, C. Huang, T. Wei +7 more
2015Biochemistry43 citations Open access
Semantic Scholar
PHRF1 promotes genome integrity by modulating non-homologous end-joining
C.-F. Chang, Po-Chen Chu, P.-Y. Wu, Meng Yu +3 more
2015Cell Death and Disease38 citations Open access
Semantic Scholar
Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures
S. Luo, Hsin-Yi Yeh, Wei-Hsuan Lan, Yi-Min Wu +9 more
2021Nature Communications34 citations Open access
Semantic Scholar
Ultrafast Water Dynamics at the Interface of the Polymerase–DNA Binding Complex
Yi Yang, Yangzhong Qin, Qing Ding, M. Bakhtina +3 more
2014Biochemistry33 citations Open access
Semantic Scholar
Phosphorylation of mRNA Decapping Protein Dcp1a by the ERK Signaling Pathway during Early Differentiation of 3T3-L1 Preadipocytes
Pei-Yu Chiang, Yu-Fang Shen, Yu-Lun Su, Ching-Han Kao +7 more
2013PLoS ONE33 citations Open access
Semantic Scholar
Functions of Some Capsular Polysaccharide Biosynthetic Genes in Klebsiella pneumoniae NTUH K-2044
Jin-Yuan Ho, Tzu-Lung Lin, Chun-Yen Li, Arwen Lee +6 more
2011PLoS ONE32 citations Open access
Semantic Scholar
Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity
Wei-chao Lee, Wen-Ling Lin, T. Matsui, E. Chen +6 more
2015Biochemistry31 citations Open access
Semantic Scholar
The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression
Wen-An Pan, Hsin-Yue Tsai, Shun-Chang Wang, Michael Hsiao +2 more
2015RNA Biology30 citations Open access
Semantic Scholar
An ATP-sensitive phosphoketolase regulates carbon fixation in cyanobacteria
Kuan-Jen Lu, Chiung-Wen Chang, Chun-Hsiung Wang, Frederic Y.-H. Chen +9 more
2023Nature Metabolism29 citations Open access
Semantic Scholar
Molecular Basis of the Essential S Phase Function of the Rad53 Checkpoint Kinase
N. Hoch, E. Chen, R. Buckland, Shun-Chung Wang +6 more
2013Molecular and Cellular Biology26 citations Open access
Semantic Scholar
Aiolos collaborates with Blimp-1 to regulate the survival of multiple myeloma cells
Kuo-Hsuan Hung, Shin-Tang Su, C-Y Chen, Pang-Hung Hsu +8 more
2016Cell Death and Differentiation25 citations Open access
Semantic Scholar
How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.
Wen-Jin Wu, M. Su, Jian-Li Wu, Sandeep Kumar +7 more
2014Journal of the American Chemical Society25 citations Open access
Semantic Scholar
Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase.
X. Zou, Yu‐Chen Liu, Ning-Shian Hsu, Chuen-Jiuan Huang +8 more
2014Acta Crystallographica Section D: Biological Crystallography25 citations
Semantic Scholar
PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase
Zih-Jie Shen, Pang-Hung Hsu, Yu-tai Su, Chia-Wei Yang +4 more
2014Nature Communications24 citations Open access
Semantic Scholar
SUMOylation of Blimp‐1 is critical for plasma cell differentiation
Hsia-Yuan Ying, Shin-Tang Su, Pang-Hung Hsu, Che-Chang Chang +5 more
2012EMBO Reports23 citations Open access
Semantic Scholar
Enzymology and Dynamics by Cryogenic Electron Microscopy.
M. Tsai, Wen-Jin Wu, M. Ho
2021Annual Review of Biophysics20 citations Open access
Semantic Scholar
Use of Quantitative Mass Spectrometric Analysis to Elucidate the Mechanisms of Phospho-priming and Auto-activation of the Checkpoint Kinase Rad53 in Vivo
E. Chen, N. Hoch, Shun-Chang Wang, A. Pellicioli +2 more
2013Molecular & Cellular Proteomics20 citations Open access
Semantic Scholar
Regioselective deacetylation based on teicoplanin-complexed Orf2* crystal structures.
H. Chan, Yu-Ting Huang, Syue-Yi Lyu, Chuen-Jiuan Huang +5 more
2011Molecular Biosystems20 citations
Semantic Scholar
Interaction between Salt-inducible Kinase 2 (SIK2) and p97/Valosin-containing Protein (VCP) Regulates Endoplasmic Reticulum (ER)-associated Protein Degradation in Mammalian Cells*
Fu-Chia Yang, Ya-Huei Lin, Wei-Hao Chen, Jing-Yi Huang +8 more
2013Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus.
Syue-Yi Lyu, Yu‐Chen Liu, Chin-Yuan Chang, Chuen-Jiuan Huang +7 more
2014Journal of the American Chemical Society18 citations
Semantic Scholar
Structural delineation of MDC1-FHA domain binding with CHK2-pThr68.
Hsin-Hui Wu, Pei-Yu Wu, Kai-Fa Huang, Y. Kao +1 more
2012Biochemistry18 citations Open access
Semantic Scholar
Binding and Enhanced Binding between Key Immunity Proteins TRAF6 and TIFA
Wei-Cheng Huang, Jiahn-Haur Liao, Tzu-Chun Hsiao, T. Wei +3 more
2018ChemBioChem17 citations
Semantic Scholar
How DNA polymerases catalyze DNA replication, repair, and mutation.
M. Tsai
2014Biochemistry17 citations
Semantic Scholar
Structural Mechanism for the Fidelity Modulation of DNA Polymerase λ.
Mu-Sen Liu, Hsin-Yue Tsai, Xiao-Xia Liu, M. Ho +2 more
2016Journal of the American Chemical Society15 citations Open access
Semantic Scholar
Tight regulation of a timed nuclear import wave of EKLF by PKCθ and FOE during Pro-E to Baso-E transition.
Y. Shyu, Tung-Liang Lee, Xin Chen, Pang-Hung Hsu +10 more
2014Developmental Cell15 citations Open access
Semantic Scholar
Evidence that P12, a specific variant of P16INK4A, plays a suppressive role in human pancreatic carcinogenesis
M. Poi, T. Knobloch, C. Yuan, M. Tsai +2 more
2013Biochemical and Biophysical Research Communications - BBRC15 citations Open access
Semantic Scholar
Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
Chin-Yu Chen, Yuan-Chih Chang, B. Lin, Kuan-Fu Lin +4 more
2019Journal of the American Chemical Society13 citations Open access
Semantic Scholar
Catalytic mechanism of DNA polymerases—Two metal ions or three?
M. Tsai
2018Protein Science13 citations Open access
Semantic Scholar
Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein.
Jennifer L. Woodring, Shao-Hung Lu, L. Krasnova, Shih-chi Wang +9 more
2019Journal of Medicinal Chemistry12 citations Open access
Semantic Scholar
Nonhydrolyzable Heptose Bis‐ and Monophosphate Analogues Modulate Pro‐inflammatory TIFA‐NF‐κB Signaling
Lina Liang, Tong-You Wade Wei, Pei-Yu Wu, W. Herrebout +2 more
2020ChemBioChem10 citations
Semantic Scholar
Probing the active site of deubiquitinase USP30 with non-canonical tryptophan analogues.
Han-Kai Jiang, Yi-Hui Wang, J. Weng, Prashant Kurkute +6 more
2020Biochemistry9 citations
Semantic Scholar
Human DNA Polymerase μ Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
Yao-Kai Chang, Ya-Ping Huang, Xiao-Xia Liu, Tzu-Ping Ko +5 more
2019Journal of the American Chemical Society9 citations Open access
Semantic Scholar
Evidence for an Enzyme Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A
Sei-hyun Choi, Byung-sun Jeon, N. Kim, Hsin-Hui Wu +7 more
2021Journal of the American Chemical Society7 citations Open access
Semantic Scholar

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