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K. Thummel · SciRah

Researcher profile · Semantic Scholar

K. Thummel

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K. Thummel — researcher profile on SciRah

h-index: 88
Works: 360
Citations: 30K

Most-cited papers

Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model
Seung‐been Lee, M. Wheeler, K. Patterson, Sean McGee +5 more
2018Genetics in Medicine132 citations Open access
Semantic Scholar
CYP3A4 mutation causes vitamin D–dependent rickets type 3
Jeffrey D. Roizen, Dong Li, L. O’Lear, M. Javaid +8 more
2018Journal of Clinical Investigation91 citations Open access
Semantic Scholar
Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences
Seung‐been Lee, M. Wheeler, K. Thummel, D. Nickerson
2019Clinical pharmacology and therapy82 citations Open access
Semantic Scholar
CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations
C. Hawkes, Dong Li, H. Hakonarson, K. Meyers +2 more
2017Journal of Clinical Endocrinology and Metabolism77 citations Open access
Semantic Scholar
Vitamin D Metabolism is Dysregulated in Asthma and Chronic Obstructive Pulmonary Disease.
David A. Jolliffe, Christos Stefanidis, Zhican Wang, N. Kermani +13 more
2020American Journal of Respiratory and Critical Care Medicine69 citations Open access
Semantic Scholar
Evaluation of Cytochrome P450-Mediated Cannabinoid-Drug Interactions in Healthy Adult Participants
Sumit Bansal, C. Zamarripa, Tory R. Spindle, Elise M. Weerts +4 more
2023Clinical pharmacology and therapy68 citations Open access
Semantic Scholar
Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
R. S. Tanna, J. Nguyen, Deena L Hadi, Preston K. Manwill +8 more
2022Pharmaceutics67 citations Open access
Semantic Scholar
Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver
Mei-Juan Xu, D. Bhatt, Catherine K. Yeung, Katrina G. Claw +11 more
2017Journal of Pharmacology and Experimental Therapeutics51 citations Open access
Semantic Scholar
Prednisone Pharmacokinetics during Pregnancy and Lactation
Rachel Ryu, T. Easterling, S. Caritis, R. Venkataramanan +10 more
2018Journal of clinical pharmacology50 citations Open access
Semantic Scholar
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity
R. Dalton, Seung‐been Lee, Katrina G. Claw, B. Prasad +14 more
2019Clinical and Translational Science48 citations Open access
Semantic Scholar
Effects of Pregnancy on the Pharmacokinetics of Metformin
Michael Z. Liao, Shannon K. Flood Nichols, Mahmoud S. Ahmed, Shannon M. Clark +14 more
2020Drug Metabolism And Disposition45 citations Open access
Semantic Scholar
Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans
T. Wong, Zhican Wang, Brian D. Chapron, Mitsunari Suzuki +13 more
2018Drug Metabolism And Disposition42 citations Open access
Semantic Scholar
Differential Effects of Oral Boluses of Vitamin D2 vs Vitamin D3 on Vitamin D Metabolism: A Randomized Controlled Trial
A. Martineau, K. Thummel, Zhican Wang, David A. Jolliffe +4 more
2019Journal of Clinical Endocrinology and Metabolism41 citations Open access
Semantic Scholar
Assessing Transporter-Mediated Natural Product-Drug Interactions via In vitro-In vivo Extrapolation: Clinical Evaluation with a Probe Cocktail
J. Nguyen, Dan-Dan Tian, R. S. Tanna, Deena L Hadi +14 more
2020Clinical pharmacology and therapy40 citations Open access
Semantic Scholar
Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People
Burhan Khan, Renee F Robinson, Alison E. Fohner, LeeAnna I. Muzquiz +14 more
2018Clinical and Translational Science38 citations Open access
Semantic Scholar
Regional Proteomic Quantification of Clinically Relevant Non-Cytochrome P450 Enzymes along the Human Small Intestine
Haeyoung Zhang, C. Wolford, A. Basit, Albert P. Li +7 more
2020Drug Metabolism And Disposition36 citations Open access
Semantic Scholar
Refined Prediction of Pharmacokinetic Kratom-Drug Interactions: Time-Dependent Inhibition Considerations
R. S. Tanna, Dan-Dan Tian, N. Cech, Nicholas H. Oberlies +3 more
2020Journal of Pharmacology and Experimental Therapeutics35 citations Open access
Semantic Scholar
Tissue Chips in Space—Challenges and Opportunities
Catherine K. Yeung, P. Koenig, Stefanie Countryman, K. Thummel +2 more
2019Clinical and Translational Science33 citations Open access
Semantic Scholar
P450 Pharmacogenetics in Indigenous North American Populations
Lindsay M. Henderson, Katrina G. Claw, E. Woodahl, Renee F Robinson +3 more
2018Journal of Personalized Medicine33 citations Open access
Semantic Scholar
An Improved Vascularized, Dual-Channel Microphysiological System Facilitates Modeling of Proximal Tubular Solute Secretion.
A. Chapron, Brian D. Chapron, Dale W. Hailey, Shih‐Yu Chang +6 more
2020ACS Pharmacology & Translational Science30 citations Open access
Semantic Scholar
Responsible Research With Urban American Indians and Alaska Natives.
Rosalina James, K. West, Katrina G. Claw, A. Echo-Hawk +6 more
2018American Journal of Public Health27 citations Open access
Semantic Scholar
Translating Kratom-Drug Interactions: From Bedside to Bench and Back
R. S. Tanna, N. Cech, Nicholas H. Oberlies, A. Rettie +2 more
2023Drug Metabolism And Disposition26 citations Open access
Semantic Scholar
Hepatic Transport of 25-Hydroxyvitamin D3 Conjugates: A Mechanism of 25-Hydroxyvitamin D3 Delivery to the Intestinal Tract
Chunying Gao, Michael Z. Liao, Lyrialle W. Han, K. Thummel +1 more
2018Drug Metabolism And Disposition26 citations Open access
Semantic Scholar
Reevaluating the Role of Megalin in Renal Vitamin D Homeostasis Using a Human Cell-Derived Microphysiological System
Brian D. Chapron, A. Chapron, Brian R. Phillips, Miracle C Okoli +4 more
2018ALTEX25 citations Open access
Semantic Scholar
Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom
R. S. Tanna, J. Nguyen, Deena L Hadi, Matthew E. Layton +6 more
2023Clinical pharmacology and therapy24 citations Open access
Semantic Scholar
Modeling Pharmacokinetic Natural Product–Drug Interactions for Decision-Making: A NaPDI Center Recommended Approach
E. J. Cox, Dan-Dan Tian, John D. Clarke, A. Rettie +4 more
2021Pharmacological Reviews22 citations Open access
Semantic Scholar
Mild Idiopathic Infantile Hypercalcemia - Part 1: Biochemical and Genetic Findings.
N. Lenherr-Taube, E. Young, M. Furman, Y. Elia +12 more
2021Journal of Clinical Endocrinology and Metabolism21 citations Open access
Semantic Scholar
Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in vitro and in vivo nicotine metabolism
Julie-Anne Tanner, Andy Z. X. Zhu, Katrina G. Claw, B. Prasad +9 more
2018Pharmacogenetics & Genomics21 citations Open access
Semantic Scholar
Vitamin D in human serum and adipose tissue after supplementation.
Cora M. Best, D. Riley, Thomas J. Laha, Hannah Pflaum +12 more
2020American Journal of Clinical Nutrition20 citations Open access
Semantic Scholar
Gutsy Science: In vitro systems of the human intestine to model oral drug disposition
Christopher M. Arian, T. Imaoka, Jade Yang, Edward J. Kelly +1 more
2021Pharmacology and Therapeutics19 citations Open access
Semantic Scholar
Pharmacogenomics of nicotine metabolism: novel CYP2A6 and CYP2B6 genetic variation patterns in Alaska Native and American Indian populations.
Katrina G. Claw, Julie A. Beans, Seung‐been Lee, Jaedon P Avey +8 more
2019Nicotine & Tobacco Research19 citations Open access
Semantic Scholar
Differences in 25-Hydroxyvitamin D Clearance by eGFR and Race: A Pharmacokinetic Study.
Simon Hsu, Leila R. Zelnick, Yvonne S. Lin, Cora M. Best +5 more
2020Journal of the American Society of Nephrology16 citations Open access
Semantic Scholar
VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People
Lindsay M. Henderson, Renee F Robinson, Lily Ray, Burhan Khan +10 more
2019Clinical and Translational Science16 citations Open access
Semantic Scholar
Pharmacodynamics of glyburide, metformin and glyburide/metformin combination therapy in the treatment of gestational diabetes mellitus
Diana L. Shuster, L. Shireman, Xiaosu Ma, D. Shen +16 more
2019Clinical pharmacology and therapy14 citations Open access
Semantic Scholar
Human Enteroid Monolayers: A Novel, Functionally-Stable Model for Investigating Oral Drug Disposition.
Christopher M. Arian, Eimear O Mahony, James W. MacDonald, Theo K. Bammler +3 more
2024Drug Metabolism And Disposition13 citations Open access
Semantic Scholar
Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function
Alison E. Fohner, R. Dalton, K. Skagen, Konner J Jackson +12 more
2021Clinical and Translational Science13 citations Open access
Semantic Scholar
Serum Vitamin D: Correlates of Baseline Concentration and Response to Supplementation in VITAL-DKD.
Cora M. Best, Leila R. Zelnick, K. Thummel, Simon Hsu +12 more
2021Journal of Clinical Endocrinology and Metabolism13 citations Open access
Semantic Scholar
Precision Medicine and Health Disparities: The Case of Pediatric Acute Lymphoblastic Leukemia
W. Burke, K. Thummel
2019Nursing Outlook13 citations Open access
Semantic Scholar
Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system
Kevin A Lidberg, Kendan A. Jones-Isaac, Jade Yang, Jacelyn Bain +10 more
2024npj Microgravity12 citations Open access
Semantic Scholar
Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects
M. McDonald, Dan-Dan Tian, K. Thummel, M. Paine +1 more
2020Drug Metabolism And Disposition12 citations Open access
Semantic Scholar
An Integrative Approach to Elucidate Mechanisms Underlying the Pharmacokinetic Goldenseal-Midazolam Interaction: Application of In Vitro Assays and Physiologically Based Pharmacokinetic Models to Understand Clinical Observations
J. Nguyen, Dan-Dan Tian, R. S. Tanna, Christopher M. Arian +4 more
2023Journal of Pharmacology and Experimental Therapeutics11 citations Open access
Semantic Scholar
Rifampin monotherapy for children with idiopathic infantile hypercalcemia
N. Lenherr-Taube, M. Furman, E. Assor, K. Thummel +2 more
2023Journal of Steroid Biochemistry and Molecular Biology11 citations Open access
Semantic Scholar
Validation of the 24,25-Dihydroxyvitamin D3 to 25-Hydroxyvitamin D3 Ratio as a Biomarker of 25-Hydroxyvitamin D3 Clearance
Simon Hsu, Leila R. Zelnick, Yvonne S. Lin, Cora M. Best +4 more
2021Journal of Steroid Biochemistry and Molecular Biology11 citations Open access
Semantic Scholar
Renal Secretion of Hydrochlorothiazide Involves Organic Anion Transporter 1/3, Organic Cation Transporter 2, and Multidrug and Toxin Extrusion Protein 2-K.
Jia-Xue Yin, D. J. Wagner, B. Prasad, N. Isoherranen +2 more
2019AJP - Renal Physiology11 citations Open access
Semantic Scholar
Co‐consuming green tea with raloxifene decreases raloxifene systemic exposure in healthy adult participants
John D. Clarke, Sabrina M. Judson, Dan-Dan Tian, Trevor O. Kirby +10 more
2023Clinical and Translational Science10 citations Open access
Semantic Scholar
Mild Idiopathic Infantile Hypercalcemia - Part 2: A Longitudinal Observational Study.
N. Lenherr-Taube, M. Furman, E. Assor, Y. Elia +4 more
2021Journal of Clinical Endocrinology and Metabolism10 citations Open access
Semantic Scholar
Bi-cultural dynamics for risk and protective factors for cardiometabolic health in an Alaska Native (Yup’ik) population
J. Philip, T. Ryman, S. Hopkins, D. O'Brien +6 more
2017PLoS ONE10 citations Open access
Semantic Scholar
Impact of a Prenatal Vitamin D Supplementation Program on Vitamin D Deficiency, Rickets and Early Childhood Caries in an Alaska Native Population
R. Singleton, Gretchen M. Day, T. Thomas, J. Klejka +9 more
2022Nutrients9 citations Open access
Semantic Scholar
Adapting regulatory drug‐drug interaction guidance to design clinical pharmacokinetic natural product‐drug interaction studies: A NaPDI Center recommended approach
E. J. Cox, A. Rettie, J. Unadkat, K. Thummel +2 more
2021Clinical and Translational Science8 citations Open access
Semantic Scholar
A Novel LC‐MS/MS Assay for Quantification of Des‐carboxy Prothrombin and Characterization of Warfarin‐Induced Changes
A. Basit, B. Prasad, Joanne K. Estergreen, D. Sabath +4 more
2020Clinical and Translational Science8 citations Open access
Semantic Scholar

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