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Leigh A. Jania · SciRah

Researcher profile · Semantic Scholar

Leigh A. Jania

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Leigh A. Jania — researcher profile on SciRah

h-index: 16
Works: 26
Citations: 1,050

Most-cited papers

NLRP1 dependent pyroptosis leads to acute lung injury and morbidity in mice
M. Kovárová, P. Hesker, Leigh A. Jania, Mytrang Nguyen +6 more
2012Journal of Immunology256 citations Open access
Semantic Scholar
COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis.
A. Lovgren, Leigh A. Jania, J. Hartney, Kelly K. Parsons +4 more
2006American Journal of Physiology - Lung cellular and Molecular Physiology131 citations
Semantic Scholar
Francisella tularensis-Infected Macrophages Release Prostaglandin E2 that Blocks T Cell Proliferation and Promotes a Th2-Like Response1
M. Woolard, Justin E. Wilson, L. Hensley, Leigh A. Jania +3 more
2007Journal of Immunology92 citations
Semantic Scholar
Microsomal Prostaglandin E Synthase-2 Is Not Essential For In Vivo Prostaglandin E2 Biosynthesis
Leigh A. Jania, S. Chandrasekharan, Michael G. Backlund, Nicholas A. Foley +5 more
2008Prostaglandins & other lipid mediators89 citations Open access
Semantic Scholar
Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease.
I. Allen, Amy J. Pace, Leigh A. Jania, J. Ledford +6 more
2006American Journal of Physiology - Lung cellular and Molecular Physiology69 citations
Semantic Scholar
Prostaglandin E2 protects lower airways against bronchoconstriction.
J. Hartney, Kenneth G. Coggins, S. Tilley, Leigh A. Jania +3 more
2006American Journal of Physiology - Lung cellular and Molecular Physiology62 citations
Semantic Scholar
A major role for the EP4 receptor in regulation of renin.
C. Facemire, Mytrang Nguyen, Leigh A. Jania, W. Beierwaltes +3 more
2011AJP - Renal Physiology46 citations Open access
Semantic Scholar
A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice.
J. Snouwaert, Rachel J. Church, Leigh A. Jania, Mytrang Nguyen +8 more
2018Cell Reports41 citations Open access
Semantic Scholar
Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement
B. Koller, J. Snouwaert, C. Douillet, Leigh A. Jania +3 more
2020Environmental Health Perspectives36 citations Open access
Semantic Scholar
Retinoid-Related Orphan Receptor γ Controls Immunoglobulin Production and Th1/Th2 Cytokine Balance in the Adaptive Immune Response to Allergen1
S. Tilley, Maisa S Jaradat, Cliona M. Stapleton, D. Dixon +8 more
2007Journal of Immunology36 citations Open access
Semantic Scholar
Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria
W. T. Barker, Ansley M. Nemeth, Sara M. Brackett, A. Basak +7 more
2019ACS Infectious Diseases32 citations Open access
Semantic Scholar
Coupling of COX-1 to mPGES1 for prostaglandin E2 biosynthesis in the murine mammary gland Published, JLR Papers in Press, October 3, 2005. DOI 10.1194/jlr.M500213-JLR200
S. Chandrasekharan, Nicholas A. Foley, Leigh A. Jania, P. Clark +2 more
2005Journal of Lipid Research30 citations Open access
Semantic Scholar
PGE2 produced by the lung augments the effector phase of allergic inflammation
Rachel J. Church, Leigh A. Jania, B. Koller
2012Journal of Immunology26 citations Open access
Semantic Scholar
Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements
J. Snouwaert, Leigh A. Jania, T. Nguyen, David R. Martinez +13 more
2023PLoS Pathogens18 citations Open access
Semantic Scholar
Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile
Kelsey A Behrens, Leigh A. Jania, J. Snouwaert, Mytrang Nguyen +4 more
2019PLoS ONE18 citations Open access
Semantic Scholar
Structure Function Studies on IMD-0354 Identifies Highly Active Colistin Adjuvants.
Ansley M. Nemeth, A. Basak, Alexander W. Weig, Santiana A. Marrujo +8 more
2019ChemMedChem16 citations Open access
Semantic Scholar
ONZIN Deficiency Attenuates Contact Hypersensitivity Responses in Mice
J. Ledford, M. Kovárová, Leigh A. Jania, Mytrang Nguyen +1 more
2012Immunology and Cell Biology16 citations Open access
Semantic Scholar
Second-Generation Tryptamine Derivatives Potently Sensitize Colistin Resistant Bacteria to Colistin.
Bradley M. Minrovic, V. B. Hubble, W. T. Barker, Leigh A. Jania +3 more
2019ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Eukaryotic Phosphatase Inhibitors Enhance Colistin Efficacy in Gram-negative Bacteria.
W. T. Barker, Leigh A. Jania, R. Melander, B. Koller +1 more
2020Chemical Biology and Drug Design10 citations Open access
Semantic Scholar
Benzimidazole Isosteres of Salicylanilides Are Highly Active Colistin Adjuvants
Haoting Li, Anne E. Mattingly, Leigh A. Jania, Richard D. Smith +4 more
2021ACS Infectious Diseases7 citations Open access
Semantic Scholar
Adjuvants restore colistin sensitivity in mouse models of highly colistin-resistant isolates, limiting bacterial proliferation and dissemination
B. H. Koller, Leigh A. Jania, Haoting Li, W. T. Barker +2 more
2024Antimicrobial Agents and Chemotherapy5 citations Open access
Semantic Scholar
Abstract 503: Prostaglandin E2 produced by tumor cells or by the host tumor microenvironment is not completely abolished by aspirin or celecoxib and limits the ability of the host immune system to control tumor growth
J. Snouwaert, Leigh A. Jania, Mytrang Nguyen, P. Dontu +4 more
2019Immunology3 citations
Semantic Scholar
IMD-0354 optimization generates potent colistin adjuvants with in vivo activity and reduced eukaryotic toxicity
Luke Cowart, Ansley M. Nemeth, Leigh A. Jania, Moira Overly +6 more
2026European journal of medicinal chemistry0 citations Open access
Semantic Scholar
Proliferation and Promotes a Th2-Like Release Prostaglandin E2 that Blocks T Cell Francisella tularensis-Infected Macrophages
J. Frelinger, Leigh A. Jania, T. Kawula, James R. Drake +3 more
20130 citations
Semantic Scholar
This information is current as Inflammation Augments the Effector Phase of Allergic Produced by the Lung 2 Prostaglandin E
Rachel J. Church, Leigh A. Jania, B. Koller
20120 citations
Semantic Scholar
Lung Injury and Morbidity in Mice NLRP1-Dependent Pyroptosis Leads to Acute
H. Koller, Lommatzsch, M. Huang, J. P. Ting +8 more
20120 citations
Semantic Scholar

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