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J. Ledford · SciRah

Researcher profile · Semantic Scholar

J. Ledford

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J. Ledford — researcher profile on SciRah

h-index: 25
Works: 100
Citations: 2,636

Most-cited papers

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children
M. Stein, C. Hrusch, J. Gozdz, C. Igartua +16 more
2016New England Journal of Medicine837 citations Open access
Semantic Scholar
Cross-Dressing the Virion: the Transcapsidation of Adeno-Associated Virus Serotypes Functionally Defines Subgroups
J. Rabinowitz, D. Bowles, Susan M. Faust, J. Ledford +2 more
2004Journal of Virology187 citations Open access
Semantic Scholar
Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight.
Maria Jimenez-Preitner, Xavier P. Berney, M. Uldry, Alessandra Vitali +3 more
2011Cell Metabolism107 citations Open access
Semantic Scholar
Impaired Host Defense in Mice Lacking ONZIN1
J. Ledford, M. Kovárová, B. Koller
2007Journal of Immunology90 citations Open access
Semantic Scholar
The role of surfactant protein A in bleomycin-induced acute lung injury.
Hisatsugu Goto, J. Ledford, S. Mukherjee, P. Noble +2 more
2010American Journal of Respiratory and Critical Care Medicine79 citations Open access
Semantic Scholar
Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.
F. Polverino, T. Wu, J. Rojas-Quintero, Xiao-Yun Wang +24 more
2021American Journal of Respiratory and Critical Care Medicine77 citations Open access
Semantic Scholar
Surfactant protein-D regulates effector cell function and fibrotic lung remodeling in response to bleomycin injury.
Yoshinori Aono, J. Ledford, S. Mukherjee, H. Ogawa +5 more
2012American Journal of Respiratory and Critical Care Medicine77 citations Open access
Semantic Scholar
Club Cell Secretory Protein Deficiency Leads to Altered Lung Function
J. Zhai, Michael Insel, K. Addison, D. Stern +12 more
2019American Journal of Respiratory and Critical Care Medicine73 citations Open access
Semantic Scholar
Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease.
I. Allen, Amy J. Pace, Leigh A. Jania, J. Ledford +6 more
2006American Journal of Physiology - Lung cellular and Molecular Physiology69 citations
Semantic Scholar
A homozygous SFTPA1 mutation drives necroptosis of type II alveolar epithelial cells in patients with idiopathic pulmonary fibrosis
Akio Takezaki, S. Tsukumo, Y. Setoguchi, J. Ledford +5 more
2019Journal of Experimental Medicine67 citations Open access
Semantic Scholar
Surfactant protein A suppresses lung cancer progression by regulating the polarization of tumor-associated macrophages.
A. Mitsuhashi, Hisatsugu Goto, T. Kuramoto, S. Tabata +11 more
2013American Journal of Pathology58 citations Open access
Semantic Scholar
Inhalation Delivery for the Treatment and Prevention of COVID-19 Infection
Basanth Babu Eedara, Wafaa Alabsi, David Encinas-Basurto, R. Polt +2 more
2021Pharmaceutics56 citations Open access
Semantic Scholar
Preformulation and Evaluation of Tofacitinib as a Therapeutic Treatment for Asthma
Usir S. Younis, E. Vallorz, K. Addison, J. Ledford +1 more
2019AAPS PharmSciTech39 citations Open access
Semantic Scholar
Obese Asthmatics Have Decreased Surfactant Protein-A Levels: Mechanisms and Implications
N. Lugogo, D. Francisco, K. Addison, A. Manne +8 more
2017Journal of Allergy and Clinical Immunology36 citations Open access
Semantic Scholar
Genes of innate immunity and the biological response to inhaled ozone
Zhuo-Wei Li, R. Tighe, Fei-Fei Feng, J. Ledford +1 more
2012Journal of biochemical and molecular toxicology36 citations Open access
Semantic Scholar
Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.
Xing-Nan Li, S. Guerra, J. Ledford, M. Kraft +18 more
2022American Journal of Respiratory and Critical Care Medicine35 citations Open access
Semantic Scholar
Surfactant Protein-A Suppresses Eosinophil-Mediated Killing of Mycoplasma pneumoniae in Allergic Lungs
J. Ledford, S. Mukherjee, M. M. Kislan, Julia L. Nugent +2 more
2012PLoS ONE34 citations Open access
Semantic Scholar
Impact of Surfactant Protein D, Interleukin-5, and Eosinophilia on Cryptococcosis
Stephanie M. Holmer, Kathy S. Evans, Yohannes G. Asfaw, Divey Saini +6 more
2013Infection and Immunity33 citations Open access
Semantic Scholar
Tollip SNP rs5743899 Modulates Human Airway Epithelial Responses to Rhinovirus Infection
Chunjian Huang, Di Jiang, Dave Francisco, Reena Berman +9 more
2016Clinical and Experimental Allergy32 citations Open access
Semantic Scholar
Collectins link innate and adaptive immunity in allergic airway disease
J. Ledford, A. Pastva, J. Wright
2010Innate Immunity29 citations Open access
Semantic Scholar
Surfactant Protein-A protects against IL-13-induced inflammation in asthma
D. Francisco, Ying Wang, M. Conway, Audriana N. Hurbon +6 more
2020Journal of Immunology28 citations Open access
Semantic Scholar
Surfactant Protein-A Inhibits Mycoplasma-Induced Dendritic Cell Maturation through Regulation of HMGB-1 Cytokine Activity
J. Ledford, Bernice Lo, M. M. Kislan, Joseph M. Thomas +5 more
2010Journal of Immunology27 citations Open access
Semantic Scholar
Circulating CC16 and Asthma: A Population-Based, Multi-Cohort Study from Early Childhood Through Adult Life.
N. Voraphani, D. Stern, J. Ledford, A. Spangenberg +17 more
2023American Journal of Respiratory and Critical Care Medicine25 citations Open access
Semantic Scholar
Advanced design and development of nanoparticle/microparticle dual-drug combination lactose carrier-free dry powder inhalation aerosols
Priya Muralidharan, Evan Mallory, Monica Malapit, Hanna Phan +3 more
2020RSC Advances25 citations Open access
Semantic Scholar
Genetic variation in Surfactant Protein-A2 (SP-A2) leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses
J. Ledford, D. Voelker, K. Addison, Ying Wang +7 more
2015Journal of Immunology25 citations Open access
Semantic Scholar
Eosinophil-associated lung diseases. A cry for surfactant proteins A and D help?
J. Ledford, K. Addison, M. Foster, L. Que
2014American Journal of Respiratory Cell and Molecular Biology25 citations Open access
Semantic Scholar
Tollip Inhibits ST2 Signaling in Airway Epithelial Cells Exposed to Type 2 Cytokines and Rhinovirus
A. Dakhama, R. Al Mubarak, N. Pavelka, D. Voelker +5 more
2019Journal of Innate Immunity24 citations Open access
Semantic Scholar
Possibilities and Pitfalls of Social Media for Translational Medicine
Suzan Dijkstra, G. Kok, J. Ledford, E. Sandalova +1 more
2018Frontiers in Medicine23 citations Open access
Semantic Scholar
The Emerging Roles of Surfactant Protein-A in Asthma
A. Dy, S. Tanyaratsrisakul, D. Voelker, J. Ledford
2018Journal of Clinical & Cellular Immunology22 citations Open access
Semantic Scholar
This information is current as Infection in Mice Mycoplasma pneumoniae SPA Preserves Airway Homeostasis During
J. Ledford, Hisatsugu Goto, E. Potts, S. Degan +7 more
200922 citations
Semantic Scholar
Toll-interacting protein (Tollip) inhibits IL-13-mediated pulmonary eosinophilic inflammation in mice
Y. Ito, N. Schaefer, Amelia Sanchez, D. Francisco +8 more
2018Journal of Innate Immunity21 citations Open access
Semantic Scholar
Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)−/− mice
Bethany J. Hsia, J. Ledford, E. Potts-Kant, Vinayak S. Nikam +5 more
2012Journal of Allergy and Clinical Immunology20 citations Open access
Semantic Scholar
CC16 Binding to α4β1 Integrin (VLA-4) Protects Against Mycoplasma pneumoniae Infection.
Michael D. L. Johnson, Usir S. Younis, Sanjay V. Menghani, K. Addison +9 more
2020American Journal of Respiratory and Critical Care Medicine18 citations Open access
Semantic Scholar
ONZIN Deficiency Attenuates Contact Hypersensitivity Responses in Mice
J. Ledford, M. Kovárová, Leigh A. Jania, Mytrang Nguyen +1 more
2012Immunology and Cell Biology16 citations Open access
Semantic Scholar
Surfactant Protein A integrates activation signal strength to differentially modulate T cell proliferation
S. Mukherjee, C. Giamberardino, Joseph M. Thomas, Kathy S. Evans +5 more
2012Journal of Immunology16 citations Open access
Semantic Scholar
High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.
A. Kummarapurugu, Shuo Zheng, J. Ledford, Sophia Karandashova +1 more
2018American Journal of Respiratory Cell and Molecular Biology14 citations Open access
Semantic Scholar
Paradoxical effects of cigarette smoke and COPD on SARS-CoV-2 infection and disease
M. Tomchaney, M. Contoli, J. Mayo, S. Baraldo +18 more
2021BMC Pulmonary Medicine13 citations Open access
Semantic Scholar
Genetic Variation in Surfactant Protein A2 Delays Resolution of Eosinophilia in Asthma
A. Dy, M. Z. Arif, K. Addison, L. Que +3 more
2019Journal of Immunology13 citations Open access
Semantic Scholar
eNAMPT Is a Novel DAMP and Therapeutic Target in Human and Murine Pulmonary Fibrosis
N. G. Casanova, J. Herazo-Maya, C. Kempf, Belinda L. Sun +30 more
2025American Journal of Respiratory Cell and Molecular Biology12 citations Open access
Semantic Scholar
Paradoxical effects of cigarette smoke and COPD on SARS-CoV2 infection and disease
M. Tomchaney, M. Contoli, J. Mayo, S. Baraldo +18 more
2020bioRxiv12 citations Open access
Semantic Scholar
A Novel in vivo System to Test Bronchodilators
K. Addison, John Morse, A. Robichaud, M. Daines +1 more
2017Journal of Infectious Pulmonary Diseases12 citations Open access
Semantic Scholar
Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A
M. Foster, J. W. Thompson, J. Ledford, Laura G. Dubois +7 more
2014Journal of Proteome Research12 citations Open access
Semantic Scholar
Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β
H. Ogawa, J. Ledford, S. Mukherjee, Yoshinori Aono +4 more
2014Respiratory Research12 citations Open access
Semantic Scholar
β-arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation
Hillary Schiff, Candy M. Rivas, W. Pederson, Estevan Sandoval +9 more
2022British Journal of Pharmacology11 citations Open access
Semantic Scholar
CC16 Binding to a 4 b 1 Integrin Protects against Mycoplasma pneumoniae Infection
Michael D. L. Johnson, Usir S. Younis, Sanjay V. Menghani, K. Addison +9 more
202111 citations
Semantic Scholar
CC16 Deficiency in the Context of Early-Life Mycoplasma pneumoniae Infection Results in Augmented Airway Responses in Adult Mice
N. Iannuzo, Michael Insel, Craig Marshall, W. Pederson +4 more
2021Infection and Immunity10 citations Open access
Semantic Scholar
Proteinase-activated receptor-2 antagonist C391 inhibits Alternaria-induced airway epithelial signalling and asthma indicators in acute exposure mouse models
Candy M. Rivas, Michael C. Yee, K. Addison, Marissa Lovett +7 more
2021British Journal of Pharmacology10 citations Open access
Semantic Scholar
Angiotensin-(1–7) Peptide Hormone Reduces Inflammation and Pathogen Burden during Mycoplasma pneumoniae Infection in Mice
Katie L Collins, Usir S. Younis, S. Tanyaratsrisakul, R. Polt +3 more
2021Pharmaceutics10 citations Open access
Semantic Scholar
Metabolomic Profiling in Mouse Model of Menopause-Associated Asthma
W. Pederson, L. Ellerman, Yan Jin, Hai-Wei Gu +1 more
2023Metabolites9 citations Open access
Semantic Scholar
SP-A Preserves Airway Homeostasis During Mycoplasma pneumoniae Infection in Mice
J. Ledford, H. Goto, E. Potts, S. Degan +7 more
2009Journal of Immunology9 citations Open access
Semantic Scholar

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