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M. Flick · SciRah

Researcher profile · Semantic Scholar

M. Flick

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M. Flick — researcher profile on SciRah

h-index: 48
Works: 242
Citations: 10K

Most-cited papers

Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier
L. M. Silva, A. Doyle, T. Greenwell-Wild, N. Dutzan +20 more
2021Science170 citations Open access
Semantic Scholar
Aortic intimal resident macrophages are essential for maintenance of the non-thrombogenic intravascular state
G. Hernandez, Fei-Yang Ma, Guadalupe Martinez, Nadia B. Firozabadi +11 more
2022Nature Cardiovascular Research57 citations Open access
Semantic Scholar
Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures
Leland S. Hu, F. D'Angelo, Taylor M. Weiskittel, F. Caruso +56 more
2023Nature Communications56 citations Open access
Semantic Scholar
Fibrinogen, Fibrin, and Fibrin Degradation Products in COVID-19
K. Kangro, A. Wolberg, M. Flick
2022Current Drug Targets45 citations Open access
Semantic Scholar
Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI
J. Molina, Kurt N. Kohler, Christopher Gager, M. J. Andersen +14 more
2024Nature Communications24 citations Open access
Semantic Scholar
Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury.
Lauren G. Poole, A. Kopec, D. Groeneveld, Asmita Pant +4 more
2021Blood23 citations Open access
Semantic Scholar
Cross-linking by tissue transglutaminase-2 alters fibrinogen-directed macrophage proinflammatory activity
Lauren G. Poole, A. Kopec, M. Flick, J. Luyendyk
2022Journal of Thrombosis and Haemostasis19 citations Open access
Semantic Scholar
Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection
Oscar A Negrón, W. Hur, Joni M. Prasad, David S. Paul +8 more
2022PLoS Pathogens18 citations Open access
Semantic Scholar
Targeting uPAR with an antibody-drug conjugate suppresses tumor growth and reshapes the immune landscape in pancreatic cancer models
Virginia Metrangolo, Michaela Hansen Blomquist, Ananya Dutta, H. Gårdsvoll +7 more
2025Science Advances17 citations Open access
Semantic Scholar
Mice expressing nonpolymerizable fibrinogen have reduced arterial and venous thrombosis with preserved hemostasis.
W. Hur, Tomohiro Kawano, J. Mwiza, D. Paul +12 more
2023Blood17 citations Open access
Semantic Scholar
Factor XIII: driving (cross-)links in hemostasis, thrombosis, and disease
J. Luyendyk, M. Flick, A. Wolberg
2025Blood16 citations
Semantic Scholar
Coagulation Signaling through PAR1 as a Therapeutic Target in Pancreatic Ductal Adenocarcinoma
Aditi Kothari, M. Flick
2021International Journal of Molecular Sciences15 citations Open access
Semantic Scholar
Novel Genetic Regulators of Fibrinogen Synthesis Identified by an In Vitro Experimental Platform
Dre'Von A. Dobson, Lori A. Holle, F.-C. Lin, J. Huffman +6 more
2022Journal of Thrombosis and Haemostasis14 citations Open access
Semantic Scholar
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD
Zhenfeng Song, Pattaraporn Thepsuwan, W. Hur, Mauricio Torres +14 more
2024Nature Communications13 citations Open access
Semantic Scholar
Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A
A. Strilchuk, W. Hur, Paul Batty, Ya-Qiu Sang +17 more
2024Science Translational Medicine13 citations Open access
Semantic Scholar
Elimination of fibrin polymer formation or crosslinking, but not fibrinogen deficiency, is protective against diet-induced obesity and associated pathologies
W. Hur, K. King, Yesha N Patel, Y-Van Nguyen +8 more
2022Journal of Thrombosis and Haemostasis13 citations Open access
Semantic Scholar
Fibrinogen γ′ promotes host survival during Staphylococcus aureus septicemia in mice
Oscar A Negrón, M. Weggeman, J. Grimbergen, Emily G. Clark +4 more
2023Journal of Thrombosis and Haemostasis12 citations Open access
Semantic Scholar
Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression
Nayela N. Chowdhury, Yi Yang, Ananya Dutta, Michelle Luo +11 more
2023Molecular Oncology11 citations Open access
Semantic Scholar
4D intravital imaging identifies platelets as the predominant cellular procoagulant surface in a mouse hemostasis model.
Abigail Ballard-Kordeliski, R. Lee, E. O'Shaughnessy, P. Kim +7 more
2024Blood10 citations Open access
Semantic Scholar
Rasa3 deficiency minimally affects thrombopoiesis but promotes severe thrombocytopenia due to integrin-dependent platelet clearance
R. Lee, Dorsaf Ghalloussi, Gabriel Harousseau, J. P. Kenny +8 more
2022JCI Insight10 citations Open access
Semantic Scholar
Plasminogen activation and plasmin activity are not necessary to prevent venous thrombosis/thromboembolism
Ya-Qiu Sang, M. Menegatti, J. Brody, K. Wiggins +9 more
2025Blood8 citations Open access
Semantic Scholar
Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI
J. Molina, Kurt N. Kohler, Christopher Gager, M. J. Andersen +14 more
2023Research Square8 citations Open access
Semantic Scholar
Depletion of fibrinogen suppresses growth of primary tumors and metastasis of pancreatic ductal adenocarcinoma (PDAC)
Nayela N. Chowdhury, Dana K. Mitchell, K. Kangro, Kierra Eldridge +19 more
2025Gastroenterology7 citations Open access
Semantic Scholar
Protease activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography
T. Rudran, S. Antoniak, M. Flick, M. H. Ginsberg +3 more
2023Journal of Thrombosis and Haemostasis6 citations Open access
Semantic Scholar
Targeting neutrophil PKM2 for stroke treatment.
M. Flick
2022Blood5 citations
Semantic Scholar
Hepatocyte-independent PAR1-biased signaling controls liver pathology in experimental obesity
H. Cline, Zi-Mu Wei, D. Groeneveld, J. Hix +7 more
2024Journal of Thrombosis and Haemostasis4 citations Open access
Semantic Scholar
Fighting Fibrin with Fibrin: Vancomycin Delivery into Coagulase-Mediated S. aureus Biofilms via Fibrin-Based Nanoparticle Binding
Grant Scull, Adrian N. Aligwekwe, Ysabel Rey, Drew Koch +9 more
2024Journal of Biomedical Materials Research. Part A4 citations Open access
Semantic Scholar
SARS-CoV-2 spike protein can bind fibrin(ogen), but does not alter plasma fibrin formation, clot structure, or lysis
K. Kangro, Samer M. Issa, A. Wolberg, M. Flick
2026Blood Advances3 citations Open access
Semantic Scholar
Altered fibrinogen γ-chain cross-linking in FibγΔ5 mice drives acute liver injury
Lauren Poole, Lauren R. Schmitt, Anthony Schulte, D. Groeneveld +7 more
2023Journal of Thrombosis and Haemostasis3 citations
Semantic Scholar
In vivo targeting of open prothrombin with the monoclonal antibody POmAb results in anticoagulation without excessive bleeding
Marisa A. Brake, Suresh Kumar, Catherine Lapointe, Glenn Merrill-Skoloff +4 more
2026Journal of Thrombosis and Haemostasis2 citations Open access
Semantic Scholar
Fibrin as a thrombin sink: a factor retaining a thrombus in the stillness phase.
A. Yakusheva, Catherine Bourdon, K. Jouffroy, Muhammad Usman Ahmed +6 more
2026Blood2 citations Open access
Semantic Scholar
Structure-functionality relationship of collagen-fibrin interpenetrating hydrogels for engineered tumor-stroma models
Sae Rome Choi, Seamus Mellican, T. J. Roberts, Se-Hong Kang +7 more
2026Acta Biomaterialia2 citations Open access
Semantic Scholar
Suppressing upregulation of fibrinogen after polytrauma mitigates thrombosis in mice
Monica S. Seadler, Francesca Ferraresso, Muskan Bansal, A. Haugen +5 more
2024Journal of Trauma and Acute Care Surgery2 citations
Semantic Scholar
Activated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation
Ya-Qiu Sang, R. Lee, Annie Luong, É. Katona +7 more
2024Blood Advances2 citations Open access
Semantic Scholar
Distinct fibrin clot characteristics in individuals with severe obesity and metabolic liver disease: 2-year follow-up after bariatric surgery
N. B. Pedersen, A. Munster, M. M. Lauridsen, M. Flick +6 more
2026Research and Practice in Thrombosis and Haemostasis1 citations Open access
Semantic Scholar
Antifibrinolytic strategies improve liver regeneration in mice and reduce posthepatectomy liver failure in patients
Zhi-Hao Li, Zi-Mu Wei, D. Groeneveld, A. Strilchuk +13 more
2026Blood1 citations Open access
Semantic Scholar
The fibrinogen αC region promotes arterial thrombosis in the context of hypofibrinogenemia
R. Lee, Francesca Ferraresso, A. Couzens, Angelica T Jameson +8 more
2026Blood1 citations Open access
Semantic Scholar
Age-associated increases in PAI-1 silenced with siRNA-lipid nanoparticles reduces thrombosis and prolongs lifespan
Francesca Ferraresso, Chad W. Skaer, Zi-Mu Wei, Manoj Paul +19 more
2026Blood1 citations Open access
Semantic Scholar
Urokinase plasminogen activator deficiency delays the development of obesity and metabolic sequelae
W. Hur, Yesha N Patel, Sara R. Abrahams, Zi-Mu Wei +9 more
2026Arteriosclerosis, Thrombosis and Vascular Biology1 citations Open access
Semantic Scholar
Fibrin and Fibrinogen Play Complex Opposing Roles in Metastasis
Balkrishan Sharma, A. Remiker, Brenton J Francisco, Cassandra Sprague +7 more
2024Blood1 citations
Semantic Scholar
Coagulation and platelet biology at the intersection of health and disease: illustrated capsules of the 11th Symposium on Hemostasis at the University of North Carolina
Maria M Aleman, G. Arepally, Trevor Baglin, L. Buitrago +12 more
2024Research and Practice in Thrombosis and Haemostasis1 citations Open access
Semantic Scholar
4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse model of hemostasis
Abigail Ballard-Kordeliski, R. Lee, Ellen C. O’Shaughnessy, P. Kim +6 more
2023bioRxiv1 citations Open access
Semantic Scholar
Thrombocytopenia in a Mouse Model of Pancreatic Cancer
Michelle Luo, Ya-Qiu Sang, Maria N. Barrachina, Andrew P. Stone +8 more
2022Blood1 citations Open access
Semantic Scholar
Development of an Actinium-225 Radioimmunoconjugate for Targeted Alpha Therapy against SARS-CoV-2
R. Pallares, M. Flick, Katherine M. Shield, Tyler A. Bailey +3 more
2022New Journal of Chemistry1 citations Open access
Semantic Scholar
Abstract 2447: Unraveling the role of the fibrinolytic system in pancreatic cancer progression
Nayela N. Chowdhury, Yi Yang, Ying-yan Shen, S. Gampala +5 more
2022Cancer Research1 citations
Semantic Scholar
Protective Role of Plasminogen Deficiency in Non-Alcoholic Fatty Liver Disease and Glucose Dysmetabolism
W. Hur, Yen Nyugen, M. Flick
2021Blood1 citations Open access
Semantic Scholar
PB1353 Fibrin(ogen) provokes metabolic dysfunction through modulation of glycine metabolism
W. Hur, Riya Shah, Yesha Patel, H. Hanes +4 more
2026Research and Practice in Thrombosis and Haemostasis0 citations Open access
Semantic Scholar
PB1351 A Novel LNP-siRNA Therapeutic Targeting Fibrinogen for Preventing Thrombosis in Preclinical Models
Muskan Bansal, Laura M. Ketelboeter, Manoj Paul, L. Nguyen +5 more
2026Research and Practice in Thrombosis and Haemostasis0 citations Open access
Semantic Scholar
OC 50.4 Fibrinogen reduction significantly decreases sepsis-driven thrombosis without provoking bleeding in mice
Catherine Lapointe, W. Hur, K. Kangro, Francesca Ferraresso +8 more
2026Research and Practice in Thrombosis and Haemostasis0 citations Open access
Semantic Scholar
Graph-based modeling of multiparametric MRI deciphers molecular states of high-grade glioma invasion with prognostic implications
M. Flick, Matthew W. Kenaston, Srijon Sarkar, Gabe M. LaFond +21 more
2026bioRxiv0 citations
Semantic Scholar

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Sara R. Abrahams×6
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