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Leah V. Schaffer · SciRah

Researcher profile · Semantic Scholar

Leah V. Schaffer

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Leah V. Schaffer — researcher profile on SciRah

h-index: 16
Works: 39
Citations: 813

Most-cited papers

Identification and Quantification of Proteoforms by Mass Spectrometry
Leah V. Schaffer, R. Millikin, Rachel M. Miller, Lissa C. Anderson +15 more
2019Proteomics171 citations Open access
Semantic Scholar
A multi-scale map of cell structure fusing protein images and interactions
Yue Qin, Edward L. Huttlin, Casper F. Winsnes, Maya L. Gosztyla +24 more
2021Nature79 citations Open access
Semantic Scholar
Global Post-Translational Modification Discovery
Qiyao Li, Michael R. Shortreed, C. Wenger, Brian L. Frey +3 more
2016Journal of Proteome Research75 citations Open access
Semantic Scholar
A five-level classification system for proteoform identifications
L. Smith, Paul M. Thomas, Michael R. Shortreed, Leah V. Schaffer +17 more
2019Nature Methods72 citations Open access
Semantic Scholar
Mapping the multiscale structure of biological systems
Leah V. Schaffer, T. Ideker
2021Cell Systems59 citations Open access
Semantic Scholar
Multimodal cell maps as a foundation for structural and functional genomics
Leah V. Schaffer, Meng-Zhou Hu, Ge-Ge Qian, Kyung-Mee Moon +30 more
2025Nature40 citations Open access
Semantic Scholar
Proteoform Suite: Software for Constructing, Quantifying, and Visualizing Proteoform Families
Anthony J. Cesnik, Michael R. Shortreed, Leah V. Schaffer, R. Knoener +6 more
2017Journal of Proteome Research34 citations Open access
Semantic Scholar
Improving Proteoform Identifications in Complex Systems Through Integration of Bottom-Up and Top-Down Data
Leah V. Schaffer, R. Millikin, Michael R. Shortreed, M. Scalf +1 more
2020Journal of Proteome Research29 citations Open access
Semantic Scholar
State of the interactomes: an evaluation of molecular networks for generating biological insights
Sarah N. Wright, Scott Colton, Leah V. Schaffer, Rudolf T. Pillich +3 more
2024Molecular Systems Biology27 citations Open access
Semantic Scholar
Elucidating Escherichia coli Proteoform Families Using Intact-Mass Proteomics and a Global PTM Discovery Database
Yunxiang Dai, Michael R. Shortreed, M. Scalf, Brian L. Frey +4 more
2017Journal of Proteome Research26 citations Open access
Semantic Scholar
Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance
Nur Zafirah Zaidan, K. J. Walker, Jaime E. Brown, Leah V. Schaffer +5 more
2018Stem Cell Reports24 citations Open access
Semantic Scholar
Expanding Proteoform Identifications in Top-Down Proteomic Analyses by Constructing Proteoform Families
Leah V. Schaffer, Michael R. Shortreed, Anthony J. Cesnik, Brian L. Frey +3 more
2017Analytical Chemistry24 citations Open access
Semantic Scholar
Advanced Strategies for Proton Transfer Reactions Coupled with Parallel Ion Parking on a 21 T FT-ICR MS for Intact Protein Analysis
Chad R. Weisbrod, Lissa C. Anderson, C. Hendrickson, Leah V. Schaffer +4 more
2021Analytical Chemistry23 citations Open access
Semantic Scholar
Identification and Quantification of Murine Mitochondrial Proteoforms Using an Integrated Top-Down and Intact-Mass Strategy
Leah V. Schaffer, Jarred W. Rensvold, Michael R. Shortreed, Anthony J. Cesnik +5 more
2018Journal of Proteome Research23 citations Open access
Semantic Scholar
Constructing Human Proteoform Families Using Intact-Mass and Top-Down Proteomics with a Multi-Protease Global Post-Translational Modification Discovery Database
Yunxiang Dai, Katherine E. Buxton, Leah V. Schaffer, Rachel M. Miller +5 more
2019Journal of Proteome Research20 citations Open access
Semantic Scholar
Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines
Timothy Clark, Jillian Mohan, Leah V. Schaffer, K. Obernier +29 more
2024bioRxiv18 citations Open access
Semantic Scholar
Intact-Mass Analysis Facilitating the Identification of Large Human Heart Proteoforms
Leah V. Schaffer, Trisha Tucholski, Michael R. Shortreed, Ying Ge +1 more
2019Analytical Chemistry14 citations Open access
Semantic Scholar
Mapping the Multiscale Proteomic Organization of Cellular and Disease Phenotypes
Anthony J. Cesnik, Leah V. Schaffer, Ishan Gaur, Mayank Jain +2 more
2024Annual Review of Biomedical Data Science11 citations Open access
Semantic Scholar
Exploring Factors Affecting Interest in Chemistry Faculty Careers Among Graduate Student Women: Results from a Local Pilot Study
Morgan E. Howe, Leah V. Schaffer, Matthew J. Styles, Samuel Pazicni
2021Journal of Chemical Education11 citations
Semantic Scholar
Electrogenerated Chemiluminescent Detection of Polyamines on a Microfluidic Device Using Micromolded Carbon Paste Microelectrodes
Erin M. Gross, Emily R. Lowry, Leah V. Schaffer, Charles S Henry
2022Electroanalysis8 citations
Semantic Scholar
ProteinAligner: A Multi-modal Pretraining Framework for Protein Foundation Models
Li Zhang, Han Guo, Leah V. Schaffer, Young Su Ko +9 more
2024bioRxiv6 citations Open access
Semantic Scholar
Micromolded Carbon Paste Microelectrodes for Electrogenerated Chemiluminescent Detection on Microfluidic Devices
Erin M. Gross, Laura R. Porter, Nicholas R. Stukel, Emily R. Lowry +6 more
2020ChemElectroChem6 citations Open access
Semantic Scholar
A tri-modal contrastive learning framework for protein representation learning
Li Zhang, Han Guo, Leah V. Schaffer, Young Su Ko +9 more
2026Cell Reports Methods4 citations Open access
Semantic Scholar
A Binary Classifier for Computing Posterior Error Probabilities in MetaMorpheus
Michael R. Shortreed, R. Millikin, Lei Liu, Zach Rolfs +4 more
2021Journal of Proteome Research4 citations Open access
Semantic Scholar
Construction of Human Proteoform Families from 21 Tesla FT-ICR Mass Spectrometry Top-Down Proteomic Data
Leah V. Schaffer, Lissa C. Anderson, D. Butcher, Michael R. Shortreed +3 more
2020Journal of Proteome Research4 citations Open access
Semantic Scholar
An adversarial scheme for integrating multi-modal data on protein function
Rami Nasser, Leah V. Schaffer, T. Ideker, Roded Sharan
2025bioRxiv3 citations Open access
Semantic Scholar
HIT-MAP: A scalable approach to multimodal mapping of subcellular organization
Ge-Ge Qian, Joonwon Kim, Richa Tiwari, B. Polacco +13 more
2026Cell Reports Methods1 citations Open access
Semantic Scholar
Cell Mapping Toolkit: an end-to-end pipeline for mapping subcellular organization
J. Lenkiewicz, Christopher Churas, Meng-Zhou Hu, Ge-Ge Qian +13 more
2025Bioinform.1 citations
Semantic Scholar
Multi-modal contrastive learning of subcellular organization using DICE
Rami Nasser, Leah V. Schaffer, T. Ideker, Roded Sharan
2024Bioinform.1 citations Open access
Semantic Scholar
State of the Interactomes: an evaluation of molecular networks for generating biological insights
Sarah N. Wright, Scott Colton, Leah V. Schaffer, Rudolf T. Pillich +3 more
2024bioRxiv1 citations Open access
Semantic Scholar
Protocol for tri-modal pretraining and downstream fine-tuning of protein representations using ProteinAligner
Han Guo, Li Zhang, Leah V. Schaffer, Young Su Ko +9 more
2026STAR Protocols0 citations Open access
Semantic Scholar
Abstract 6902: Remodeling of cancer cell architecture by chemotherapy.
Ge-Ge Qian, Xiao-Yu Zhao, Leah V. Schaffer, Kyung-Mee Moon +4 more
2026Cancer Research0 citations
Semantic Scholar
Publisher Correction: Multimodal cell maps as a foundation for structural and functional genomics
Leah V. Schaffer, Meng-Zhou Hu, Ge-Ge Qian, Kyung-Mee Moon +30 more
2025Nature0 citations Open access
Semantic Scholar
Unifying proteomic technologies with ProteinProjector
Leah V. Schaffer, Mayank Jain, Rami Nasser, Roded Sharan +1 more
2025Bioinformatics Advances0 citations
Semantic Scholar
Abstract 7101: Remodeling of cancer cells by chemotherapy
Ge-Ge Qian, Leah V. Schaffer, Kyung-Mee Moon, Leonard Foster +4 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 2348: A global multiscale map of protein assemblies from integration of protein interactions and images
Leah V. Schaffer, Meng-Zhou Hu, Edward L. Huttlin, Ge-Ge Qian +14 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 6543: A map of osteosarcoma cell architecture reveals convergence of pediatric cancer mutations on protein assemblies
Meng-Zhou Hu, Leah V. Schaffer, Edward L. Huttlin, Ge-Ge Qian +15 more
2024Cancer Research0 citations
Semantic Scholar
Proteoform Analysis and Construction of Proteoform Families in Proteoform Suite
Leah V. Schaffer, Michael R. Shortreed, L. Smith
2022Methods in molecular biology0 citations Open access
Semantic Scholar
Construction of Human Proteoform Families from 21 Tesla FT-ICR Mass Spectrometry Top-Down Proteomic Data
Leah V. Schaffer, Lissa C. Anderson, D. Butcher, Michael R. Shortreed +4 more
20210 citations
Semantic Scholar

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