Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Hong He · SciRah

Researcher profile · Semantic Scholar

Hong He

Share profile

Hong He — researcher profile on SciRah

h-index: 23
Works: 63
Citations: 1,379

Most-cited papers

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways.
Nhi Huynh, Kevin H Liu, G. Baldwin, Hong He
2010Biochimica et Biophysica Acta105 citations Open access
Semantic Scholar
PAK1-blockers: Potential Therapeutics against COVID-19
H. Maruta, Hong He
2020Medicine in Drug Discovery102 citations Open access
Semantic Scholar
Caprin-1 is a novel microRNA-223 target for regulating the proliferation and invasion of human breast cancer cells.
Bo Gong, He-Yu Hu, Jia Chen, S. Cao +6 more
2013Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie85 citations
Semantic Scholar
PAK1 interacts with beta-catenin and is required for the regulation of the beta-catenin signalling pathway by gastrins.
Hong He, A. Shulkes, G. Baldwin
2008Biochimica et Biophysica Acta68 citations Open access
Semantic Scholar
Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases
D. Yeo, Nhi Huynh, J. Beutler, C. Christophi +4 more
2014Cancer Letters66 citations Open access
Semantic Scholar
P-21 activated kinase 1 knockdown inhibits β-catenin signalling and blocks colorectal cancer growth.
Hong He, Nhi Huynh, Kevin H Liu, C. Malcontenti‐Wilson +4 more
2012Cancer Letters56 citations
Semantic Scholar
Signal therapy for RAS-induced cancers in combination of AG 879 and PP1, specific inhibitors for ErbB2 and Src family kinases, that block PAK activation.
Hong He, Y. Hirokawa, E. Manser, L. Lim +2 more
2001Cancer Journal55 citations
Semantic Scholar
FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine
D. Yeo, Hong He, O. Patel, A. Lowy +2 more
2016BMC Cancer54 citations Open access
Semantic Scholar
Inhibition of PAK1 suppresses pancreatic cancer by stimulation of anti-tumour immunity through down-regulation of PD-L1.
Kai Wang, Y. Zhan, Nhi Huynh, Chelsea J. Dumesny +9 more
2019Cancer Letters47 citations
Semantic Scholar
Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer
Golnaz Sharafi, Hong He, M. Nikfarjam
2019Journal of Pancreatic Cancer40 citations Open access
Semantic Scholar
Cannabinoids Inhibited Pancreatic Cancer via P-21 Activated Kinase 1 Mediated Pathway
Yang Yang, Nhi Huynh, Chelsea J. Dumesny, Kai Wang +2 more
2020International Journal of Molecular Sciences39 citations Open access
Semantic Scholar
Functions of the CXC ligand family in the pancreatic tumor microenvironment.
Nien-Hung Lee, M. Nikfarjam, Hong He
2018Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]39 citations
Semantic Scholar
Depletion of p21-activated kinase 1 up-regulates the immune system of APC∆14/+ mice and inhibits intestinal tumorigenesis
Nhi Huynh, Kai Wang, Mildred Yim, Chelsea J. Dumesny +4 more
2017BMC Cancer38 citations Open access
Semantic Scholar
p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation
Kai Wang, G. Baldwin, M. Nikfarjam, Hong He
2018World Journal of Gastroenterology35 citations Open access
Semantic Scholar
Inhibition of group 1 p21‐activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer
D. Yeo, P. Phillips, Graham S. Baldwin, Hong He +1 more
2017International Journal of Cancer34 citations Open access
Semantic Scholar
P21-activated kinase 1 promotes colorectal cancer survival by up-regulation of hypoxia-inducible factor-1α.
Kevin H Liu, Nhi Huynh, O. Patel, A. Shulkes +2 more
2013Cancer Letters33 citations Open access
Semantic Scholar
Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins.
Hong He, Mildred Yim, Kevin H Liu, Stephen Cody +2 more
2008Cellular Signalling33 citations
Semantic Scholar
Up-regulation of stem cell markers by P21-activated kinase 1 contributes to 5-fluorouracil resistance of colorectal cancer
Nhi Huynh, A. Shulkes, G. Baldwin, Hong He
2016Cancer Biology & Therapy29 citations Open access
Semantic Scholar
Glycine-extended gastrin stimulates cell proliferation and migration through a Rho- and ROCK-dependent pathway, not a Rac/Cdc42-dependent pathway.
Hong He, J. Pannequin, John-Paul Tantiongco, A. Shulkes +1 more
2005American Journal of Physiology - Gastrointestinal and Liver Physiology29 citations
Semantic Scholar
Total pancreatectomy for the treatment of pancreatic neoplasms
M. Nikfarjam, N. Low, L. Weinberg, Ping H. Chia +2 more
2014ANZ journal of surgery28 citations
Semantic Scholar
A novel PAK4 inhibitor suppresses pancreatic cancer growth and enhances the inhibitory effect of gemcitabine
Hong He, Chelsea J. Dumesny, C. Ang, Li Dong +3 more
2021Translational Oncology26 citations Open access
Semantic Scholar
The trilogy of P21 activated kinase, autophagy and immune evasion in pancreatic ductal adenocarcinoma.
Yi Ma, M. Nikfarjam, Hong He
2022Cancer Letters24 citations
Semantic Scholar
G proteins, phosphoinositides, and actin‐cytoskeleton in the control of cancer growth
H. Maruta, Hong He, A. Tikoo, T. Vương +1 more
1999Microscopy research and technique (Print)24 citations
Semantic Scholar
Inhibition of p21 activated kinase enhances tumour immune response and sensitizes pancreatic cancer to gemcitabine.
Kai Wang, Nhi Huynh, Xiao Wang, G. Baldwin +2 more
2017International Journal of Oncology23 citations Open access
Semantic Scholar
p21-activated kinases and gastrointestinal cancer.
Hong He, G. Baldwin
2013Biochimica et Biophysica Acta23 citations Open access
Semantic Scholar
Glaucarubinone inhibits colorectal cancer growth by suppression of hypoxia-inducible factor 1α and β-catenin via a p-21 activated kinase 1-dependent pathway
Nhi Huynh, J. Beutler, A. Shulkes, G. Baldwin +1 more
2014Biochimica et Biophysica Acta22 citations Open access
Semantic Scholar
Antitumor effects of all-trans retinoic acid and its synergism with gemcitabine are associated with downregulation of p21-activated kinases in pancreatic cancer.
Kai Wang, Graham S. Baldwin, M. Nikfarjam, Hong He
2019American Journal of Physiology - Gastrointestinal and Liver Physiology21 citations
Semantic Scholar
Pancreatic Tumor Microenvironment.
Kai Wang, Hong He
2020Advances in Experimental Medicine and Biology20 citations
Semantic Scholar
Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis
A. Poh, M. O'Brien, D. Chisanga, Hong He +13 more
2022Cell Reports17 citations Open access
Semantic Scholar
PAK inhibition by PF-3758309 enhanced the sensitivity of multiple chemotherapeutic reagents in patient-derived pancreatic cancer cell lines.
Kai Wang, Nhi Huynh, Xiao Wang, M. Pajic +5 more
2019American journal of translational research16 citations
Semantic Scholar
Rho GTPases and p21-activated kinase in the regulation of proliferation and apoptosis by gastrins.
Hong He, G. Baldwin
2008International Journal of Biochemistry and Cell Biology14 citations
Semantic Scholar
Inhibition of P21-activated kinases 1 and 4 synergistically suppresses the growth of pancreatic cancer by stimulating anti-tumour immunity
Yi Ma, Chelsea J. Dumesny, Li Dong, Ching-Seng Ang +4 more
2024Cell Communication and Signaling13 citations Open access
Semantic Scholar
Comparison of Two Syngeneic Orthotopic Murine Models of Pancreatic Adenocarcinoma
M. Nikfarjam, D. Yeo, Hong He, G. Baldwin +6 more
2013Journal of investigative surgery12 citations
Semantic Scholar
Biological activity and ferric ion binding of fragments of glycine-extended gastrin.
Hong He, B. Shehan, K. Barnham, R. Norton +2 more
2004Biochemistry12 citations
Semantic Scholar
PAK1 inhibition increases TRIM21-induced PD-L1 degradation and enhances responses to anti-PD-1 therapy in pancreatic cancer.
Kai Wang, Lili Yan, Xun Qiu, Huan Chen +7 more
2024Biochimica et Biophysica Acta - Molecular Basis of Disease11 citations Open access
Semantic Scholar
PAK in Pancreatic Cancer-Associated Vasculature: Implications for Therapeutic Response
Arian Ansardamavandi, M. Nikfarjam, Hong He
2023Cells9 citations Open access
Semantic Scholar
Demonstration and biological significance of a gastrin‐P21‐activated kinase 1 feedback loop in colorectal cancer cells
Nhi Huynh, Kevin H Liu, Mildred Yim, A. Shulkes +2 more
2014Physiological Reports9 citations Open access
Semantic Scholar
p-21-Activated kinase 1 mediates gastrin-stimulated proliferation in the colorectal mucosa via multiple signaling pathways.
Nhi Huynh, Mildred Yim, J. Chernoff, A. Shulkes +2 more
2013American Journal of Physiology - Gastrointestinal and Liver Physiology9 citations Open access
Semantic Scholar
Glaucarubinone Combined with Gemcitabine Improves Pancreatic Cancer Survival in an Immunocompetent Orthotopic Murine Model
D. Yeo, Nhi Huynh, J. Beutler, G. Baldwin +2 more
2016Journal of investigative surgery8 citations
Semantic Scholar
p21-activated kinase family: promising new drug targets
Nhi Huynh, Hong He
20157 citations Open access
Semantic Scholar
ATRA sensitized the response of hepatocellular carcinoma to Sorafenib by downregulation of p21-activated kinase 1
Kai Wang, Xun Qiu, Zhen-Sheng Zhang, Han-Zhi Xu +8 more
2023Cell Communication and Signaling6 citations Open access
Semantic Scholar
P-21 Activated Kinases in Liver Disorders
Xun Qiu, Han-Zhi Xu, Kai Wang, Feng-Qiang Gao +2 more
2023Cancers6 citations Open access
Semantic Scholar
Knockout of p21-Activated Kinase 4 Stimulates MHC I Expression of Pancreatic Cancer Cells via an Autophagy-Independent Pathway
Yi Ma, Chelsea J. Dumesny, Li Dong, Ching-Seng Ang +2 more
2025Cancers5 citations Open access
Semantic Scholar
P-21 Kinase 1 or 4 Knockout Stimulated Anti-Tumour Immunity Against Pancreatic Cancer by Enhancing Vascular Normalisation
Arian Ansardamavandi, Chelsea J. Dumesny, Yi Ma, Li Dong +4 more
2025International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Signature of arylacetamide deacetylase expression is associated with prognosis and immune infiltration in ovarian cancer
Jian-Guo Feng, Hong He
2021Obstetrics & Gynecology Science5 citations Open access
Semantic Scholar
CXCL5 knockdown attenuated gemcitabine resistance of pancreatic cancer through regulation of cancer cells and tumour stroma.
Nien-Hung Lee, Yi Ma, C. Ang, Chelsea J. Dumesny +5 more
2023American journal of translational research4 citations
Semantic Scholar
Kakonein restores hyperglycemia‐induced macrophage digestion dysfunction through regulation of cathepsin B‐dependent NLRP3 inflammasome activation
Da-wei Lian, Li Zhu, Yun-Hong Yu, Xiaojuan Zhang +13 more
2022Journal of Leukocyte Biology4 citations Open access
Semantic Scholar
Targeting PAK1 or PAK4 Uncovers Different Mechanisms of Vascular Reprogramming in Pancreatic Cancer
Arian Ansardamavandi, Chelsea J. Dumesny, Sarah L. Ellis, Ching-Seng Ang +2 more
2025Cells3 citations Open access
Semantic Scholar
The Effects of PAK-Regulated Tumour Vasculature on Gemcitabine Response of Pancreatic Cancer
Arian Ansardamavandi, Chelsea J. Dumesny, Yi Ma, Li Dong +4 more
2025Cancers3 citations Open access
Semantic Scholar
P-038FRAX597, a PAK1 inhibitor, synergises with gemcitabine in the reduction of pancreatic cancer growth
D. Yeo, Hong He, Graham S. Baldwin, M. Nikfarjam
20152 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

M. Nikfarjam×26
Invite
M. Nikfarjam — researcher profile on SciRah
G. Baldwin×22
Invite
G. Baldwin — researcher profile on SciRah
Nhi Huynh×16
Invite
Nhi Huynh — researcher profile on SciRah
A. Shulkes×11
Invite
A. Shulkes — researcher profile on SciRah

Chelsea J. Dumesny

×10

Invite

Chelsea J. Dumesny — researcher profile on SciRah

Invite

Kai Wang — researcher profile on SciRah

Invite

Yi Ma — researcher profile on SciRah

Invite

D. Yeo — researcher profile on SciRah

Invite

Kevin H Liu — researcher profile on SciRah

Invite

Li Dong — researcher profile on SciRah

Ching-Seng Ang×5

Invite

Ching-Seng Ang — researcher profile on SciRah

C. Christophi×4

Invite

C. Christophi — researcher profile on SciRah