Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

R. Speck · SciRah

Researcher profile · Semantic Scholar

R. Speck

Share profile

R. Speck — researcher profile on SciRah

h-index: 38
Works: 132
Citations: 4,367

Most-cited papers

Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2−/−γc−/− mice
Stefan Baenziger, R. Tussiwand, E. Schlaepfer, L. Mazzucchelli +9 more
2006Proceedings of the National Academy of Sciences of the United States of America205 citations Open access
Semantic Scholar
Broad-range 16S rRNA gene polymerase chain reaction for diagnosis of culture-negative bacterial infections.
S. Rampini, G. Bloemberg, P. Keller, Andrea C. Büchler +3 more
2011Clinical Infectious Diseases203 citations Open access
Semantic Scholar
Antigen kinetics determines immune reactivity
P. Johansen, T. Storni, Lorna Rettig, Zhiyong Qiu +10 more
2008Proceedings of the National Academy of Sciences of the United States of America195 citations Open access
Semantic Scholar
Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection
P. Bochud, M. Hersberger, P. Taffé, M. Bochud +7 more
2007AIDS (London)169 citations Open access
Semantic Scholar
Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology.
Stefan Baenziger, M. Heikenwalder, P. Johansen, E. Schlaepfer +7 more
2009Blood164 citations Open access
Semantic Scholar
TLR7/8 Triggering Exerts Opposing Effects in Acute versus Latent HIV Infection1
E. Schlaepfer, A. Audigé, H. Joller, R. Speck
2006Journal of Immunology127 citations
Semantic Scholar
Plasma cell toll‐like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production
M. Dörner, S. Brandt, M. Tinguely, F. Zucol +6 more
2009Immunology117 citations Open access
Semantic Scholar
Long lasting control of viral rebound with a new drug ABX464 targeting Rev – mediated viral RNA biogenesis
Noëlie Campos, R. Myburgh, A. Garcel, A. Vautrin +15 more
2015Retrovirology91 citations Open access
Semantic Scholar
Disseminated and sustained HIV-infection in CD34+ cord blood cell transplanted Rag2-/-gc-/- mice
Stefan Baenziger, R. Tussiwand, E. Schlaepfer, L. Mazzucchelli +9 more
2006Retrovirology85 citations Open access
Semantic Scholar
Repeated Cycles of Recombinant Human Interleukin 7 in HIV-Infected Patients With Low CD4 T-Cell Reconstitution on Antiretroviral Therapy: Results of 2 Phase II Multicenter Studies.
R. Thiébaut, A. Jarne, J. Routy, I. Sereti +13 more
2016Clinical Infectious Diseases77 citations Open access
Semantic Scholar
Humanized Mice Recapitulate Key Features of HIV-1 Infection: A Novel Concept Using Long-Acting Anti-Retroviral Drugs for Treating HIV-1
M. Nischang, Roger P. M. Sutmuller, Gustavo Gers-Huber, A. Audigé +12 more
2012PLoS ONE77 citations Open access
Semantic Scholar
Disturbance of the gut-associated lymphoid tissue is associated with disease progression in chronic HIV infection
Ursula Hofer, R. Speck
2009Seminars in Immunopathology70 citations Open access
Semantic Scholar
HIV-1 Transmission During Recent Infection and During Treatment Interruptions as Major Drivers of New Infections in the Swiss HIV Cohort Study.
A. Marzel, M. Shilaih, Wan-Lin Yang, J. Böni +61 more
2016Clinical Infectious Diseases67 citations Open access
Semantic Scholar
Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012.
Wan-Lin Yang, R. Kouyos, A. Scherrer, J. Böni +62 more
2015Journal of Infectious Diseases66 citations Open access
Semantic Scholar
Inadequate Clearance of Translocated Bacterial Products in HIV-Infected Humanized Mice
Ursula Hofer, E. Schlaepfer, Stefan Baenziger, M. Nischang +5 more
2010PLoS Pathogens65 citations Open access
Semantic Scholar
Emergence of Acquired HIV-1 Drug Resistance Almost Stopped in Switzerland: A 15-Year Prospective Cohort Analysis.
A. Scherrer, V. von Wyl, Wan-Lin Yang, R. Kouyos +61 more
2016Clinical Infectious Diseases63 citations Open access
Semantic Scholar
TLR8 Activates HIV from Latently Infected Cells of Myeloid-Monocytic Origin Directly via the MAPK Pathway and from Latently Infected CD4+ T Cells Indirectly via TNF-α
E. Schlaepfer, R. Speck
2011Journal of Immunology58 citations Open access
Semantic Scholar
Long-term leukocyte reconstitution in NSG mice transplanted with human cord blood hematopoietic stem and progenitor cells
A. Audigé, Mary-Aude Rochat, Duo Li, S. Ivic +9 more
2017BMC Immunology53 citations Open access
Semantic Scholar
Importance of Baseline Prognostic Factors With Increasing Time Since Initiation of Highly Active Antiretroviral Therapy: Collaborative Analysis of Cohorts of HIV-1-Infected Patients
J. Sterne, M. May, C. Sabin, Andrew N. Phillips +496 more
2007Journal of Acquired Immune Deficiency Syndromes49 citations Open access
Semantic Scholar
Triggering TLR2, -3, -4, -5, and -8 Reinforces the Restrictive Nature of M1- and M2-Polarized Macrophages to HIV
E. Schlaepfer, Mary-Aude Rochat, Li Duo, R. Speck
2014Journal of Virology45 citations Open access
Semantic Scholar
Anti-HIV Activity Mediated by Natural Killer and CD8+ Cells after Toll-Like Receptor 7/8 Triggering
E. Schlaepfer, R. Speck
2008PLoS ONE42 citations Open access
Semantic Scholar
Immune activation suppresses initiation of lytic Epstein‐Barr virus infection
K. Ladell, M. Dörner, L. Zauner, C. Berger +5 more
2007Cellular Microbiology41 citations Open access
Semantic Scholar
Antiviral Activity of HIV gp120-Targeting Bispecific T Cell Engager Antibody Constructs
Johannes Brozy, E. Schlaepfer, C. Mueller, Mary-Aude Rochat +7 more
2018Journal of Virology40 citations Open access
Semantic Scholar
Modeling HIV infection and therapies in humanized mice.
M. Nischang, Gustavo Gers-Huber, A. Audigé, R. Akkina +1 more
2012Swiss medical weekly40 citations Open access
Semantic Scholar
RAG2−/−γc−/− Mice Transplanted with CD34+ Cells from Human Cord Blood Show Low Levels of Intestinal Engraftment and Are Resistant to Rectal Transmission of Human Immunodeficiency Virus
Ursula Hofer, Stefan Baenziger, M. Heikenwalder, E. Schlaepfer +4 more
2008Journal of Virology39 citations Open access
Semantic Scholar
HIV interferes with SOCS‐1 and ‐3 expression levels driving immune activation
Regina C. Miller, E. Schlaepfer, Stefan Baenziger, R. Crameri +5 more
2011European Journal of Immunology38 citations Open access
Semantic Scholar
Distinct Ex Vivo Susceptibility of B-Cell Subsets to Epstein-Barr Virus Infection According to Differentiation Status and Tissue Origin
M. Dörner, F. Zucol, C. Berger, R. Byland +4 more
2008Journal of Virology38 citations Open access
Semantic Scholar
Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice
R. Myburgh, S. Ivic, M. Pepper, Gustavo Gers-Huber +9 more
2015Journal of Virology37 citations Open access
Semantic Scholar
Anti-HIV State but Not Apoptosis Depends on IFN Signature in CD4+ T Cells
A. Audigé, M. Urosevic, E. Schlaepfer, R. Walker +6 more
2006Journal of Immunology37 citations Open access
Semantic Scholar
Dose-dependent influence of didanosine on immune recovery in HIV-infected patients treated with tenofovir
U. Karrer, B. Ledergerber, H. Furrer, L. Elzi +8 more
2005AIDS (London)36 citations Open access
Semantic Scholar
EBV renders B cells susceptible to HIV-1 in humanized mice
Donal McHugh, R. Myburgh, N. Caduff, M. Spohn +30 more
2020Life Science Alliance34 citations Open access
Semantic Scholar
Antibiotic susceptibility of Clostridium difficile is similar worldwide over two decades despite widespread use of broad-spectrum antibiotics: an analysis done at the University Hospital of Zurich
Andrea C. Büchler, S. Rampini, Simon Stelling, B. Ledergerber +5 more
2014BMC Infectious Diseases34 citations Open access
Semantic Scholar
TLR9 triggering in Burkitt's lymphoma cell lines suppresses the EBV BZLF1 transcription via histone modification
L. Zauner, G. T. Melroe, Jürg A. Sigrist, M. Rechsteiner +7 more
2010Oncogene34 citations Open access
Semantic Scholar
Promising Role of Toll-Like Receptor 8 Agonist in Concert with Prostratin for Activation of Silent HIV
Mary-Aude Rochat, E. Schlaepfer, R. Speck
2016Journal of Virology30 citations Open access
Semantic Scholar
Adaptation of the Ultrasensitive HIV-1 p24 Antigen Assay to Dried Blood Spot Testing
M. Knuchel, Boniphace S. Jullu, Cyril Shah, Z. Tomasik +7 more
2007Journal of Acquired Immune Deficiency Syndromes30 citations Open access
Semantic Scholar
HIV-specific cellular immune response is inversely correlated with disease progression as defined by decline of CD4+ T cells in relation to HIV RNA load.
A. Oxenius, D. Price, M. Hersberger, E. Schlaepfer +9 more
2004Journal of Infectious Diseases28 citations Open access
Semantic Scholar
β1 Integrin Expression Increases Susceptibility of Memory B Cells to Epstein-Barr Virus Infection
M. Dörner, F. Zucol, D. Alessi, S. Haerle +8 more
2010Journal of Virology27 citations Open access
Semantic Scholar
Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
V. Cecchinato, E. Bernasconi, R. Speck, M. Proietti +9 more
2017Journal of Immunology26 citations Open access
Semantic Scholar
Optimization of Critical Hairpin Features Allows miRNA-based Gene Knockdown Upon Single-copy Transduction
R. Myburgh, Ophélie Cherpin, E. Schlaepfer, H. Rehrauer +3 more
2014Molecular Therapy: Nucleic Acids26 citations Open access
Semantic Scholar
Similar efficacy of broad-range ITS PCR and conventional fungal culture for diagnosing fungal infections in non-immunocompromised patients
S. Rampini, A. Zbinden, R. Speck, G. Bloemberg
2016BMC Microbiology24 citations Open access
Semantic Scholar
Ultrasensitive quantitative HIV-1 p24 antigen assay adapted to dried plasma spots to improve treatment monitoring in low-resource settings.
M. Knuchel, Z. Tomasik, R. Speck, R. Lüthy +1 more
2006Journal of Clinical Virology21 citations
Semantic Scholar
Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis
T. Turk, N. Bachmann, Claus Kadelka, J. Böni +60 more
2017eLife18 citations Open access
Semantic Scholar
{beta}1 Integrin Expression Increases Susceptibility of Memory B-Cells to EBV Infection
M. Dörner, F. Zucol, D. Alessi, S. Haerle +8 more
201018 citations
Semantic Scholar
Optimizing Synthetic miRNA Minigene Architecture for Efficient miRNA Hairpin Concatenation and Multi-target Gene Knockdown
F. Rousset, P. Salmon, S. Bredl, Ophélie Cherpin +8 more
2018Molecular Therapy: Nucleic Acids16 citations Open access
Semantic Scholar
Uncoupled Anti-HIV and Immune-Enhancing Effects when Combining IFN-α and IL-71
A. Audigé, E. Schlaepfer, H. Joller, R. Speck
2005Journal of Immunology16 citations Open access
Semantic Scholar
The Humanized Mouse Model: What Added Value Does It Offer for HIV Research?
Luca Baroncini, S. Bredl, Kadzioch P. Nicole, R. Speck
2023Pathogens15 citations Open access
Semantic Scholar
Dose-Dependent Differences in HIV Inhibition by Different Interferon Alpha Subtypes While Having Overall Similar Biologic Effects
E. Schlaepfer, Audrey Fahrny, Maarja Gruenbach, S. Kuster +3 more
2019Msphere15 citations Open access
Semantic Scholar
Monitoring HIV DNA and cellular activation markers in HIV-infected humanized mice under cART
Mary-Aude Rochat, E. Schlaepfer, S. Kuster, Duo Li +4 more
2018Virology Journal15 citations Open access
Semantic Scholar
Early gene expression changes by Epstein‐Barr virus infection of B‐cells indicate CDKs and survivin as therapeutic targets for post‐transplant lymphoproliferative diseases
Michele Bernasconi, S. Ueda, Patricia Krukowski, B. Bornhauser +10 more
2013International Journal of Cancer15 citations Open access
Semantic Scholar
Low Postseroconversion CD4 Count and Rapid Decrease of CD4 Density Identify HIV+ Fast Progressors
A. Audigé, P. Taffé, M. Rickenbach, M. Battegay +3 more
2010AIDS Research and Human Retroviruses15 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

E. Schlaepfer×21
Invite
E. Schlaepfer — researcher profile on SciRah
D. Nadal×13
Invite
D. Nadal — researcher profile on SciRah
M. Battegay×12
Invite
M. Battegay — researcher profile on SciRah
J. Böni×11
Invite
J. Böni — researcher profile on SciRah

×10

Invite

A. Audigé — researcher profile on SciRah

E. Bernasconi×10

Invite

E. Bernasconi — researcher profile on SciRah

Invite

T. Klimkait — researcher profile on SciRah

Invite

H. Furrer — researcher profile on SciRah

M. Cavassini×9

Invite

M. Cavassini — researcher profile on SciRah

Invite

P. Vernazza — researcher profile on SciRah

Invite

V. Aubert — researcher profile on SciRah

Stefan Baenziger×7

Invite

Stefan Baenziger — researcher profile on SciRah