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A. Carr · SciRah

Researcher profile · Semantic Scholar

A. Carr

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A. Carr — researcher profile on SciRah

h-index: 39
Works: 89
Citations: 5,854

Most-cited papers

Evidence-based recommendations for the role of exercise in the management of osteoarthritis of the hip or knee--the MOVE consensus.
E. Roddy, Wei-Ya Zhang, M. Doherty, N. Arden +16 more
2005Rheumatology569 citations Open access
Semantic Scholar
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
C. Boer, K. Hatzikotoulas, L. Southam, L. Stefánsdóttir +151 more
2021Cell433 citations Open access
Semantic Scholar
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study
E. Zeggini, K. Panoutsopoulou, L. Southam, N. W. Rayner +72 more
2012The Lancet424 citations Open access
Semantic Scholar
UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte
R. Neame, A. Carr, Kenneth W. Muir, Michael Doherty
2003Annals of the Rheumatic Diseases238 citations Open access
Semantic Scholar
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.
H. Kerkhof, R. Lories, I. Meulenbelt, I. Jónsdóttir +38 more
2010Arthritis & Rheumatism222 citations Open access
Semantic Scholar
Large-Scale Analysis of Association Between GDF5 and FRZB Variants and Osteoarthritis of the Hip, Knee, and Hand
E. Evangelou, K. Chapman, I. Meulenbelt, F. Karassa +34 more
2009Arthritis & Rheumatism215 citations Open access
Semantic Scholar
Genetic influences in the aetiology of tears of the rotator cuff. Sibling risk of a full-thickness tear.
P. Harvie, S. Ostlere, J. Teh, E. Mcnally +4 more
2004Journal of Bone and Joint Surgery-british Volume174 citations Open access
Semantic Scholar
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
E. Evangelou, A. Valdes, H. Kerkhof, U. Styrkársdóttir +67 more
2010Annals of the Rheumatic Diseases171 citations Open access
Semantic Scholar
Genetic influences in the aetiology of femoroacetabular impingement: a sibling study.
T. Pollard, R. Villar, M. Norton, E. Fern +3 more
2010Journal of Bone and Joint Surgery-british Volume159 citations
Semantic Scholar
A variant in MCF2L is associated with osteoarthritis.
A. Day-Williams, L. Southam, K. Panoutsopoulou, N. W. Rayner +41 more
2011American Journal of Human Genetics148 citations Open access
Semantic Scholar
Suggestive Linkage of the Parathyroid Receptor Type 1 to Osteoporosis
E. Duncan, Matthew A. Brown, J. Sinsheimer, J. Bell +3 more
1999Journal of Bone and Mineral Research141 citations Open access
Semantic Scholar
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
K. Panoutsopoulou, L. Southam, K. Elliott, N. Wrayner +71 more
2010Annals of the Rheumatic Diseases140 citations Open access
Semantic Scholar
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip
E. Evangelou, H. Kerkhof, U. Styrkársdóttir, E. Ntzani +62 more
2013Annals of the Rheumatic Diseases138 citations Open access
Semantic Scholar
Functional Analysis of the Osteoarthritis Susceptibility–Associated GDF5 Regulatory Polymorphism
R. Egli, L. Southam, J. Wilkins, I. Lorenzen +5 more
2009Arthritis & Rheumatism137 citations Open access
Semantic Scholar
Assessment of Osteoarthritis Candidate Genes in a Meta-Analysis of Nine Genome-Wide Association Studies
C. Rodriguez-Fontenla, M. Calaza, E. Evangelou, A. Valdes +43 more
2014Arthritis & Rheumatology131 citations Open access
Semantic Scholar
Design and conduct of clinical trials in patients with osteoarthritis of the hand: recommendations from a task force of the Osteoarthritis Research Society International.
E. Maheu, R. Altman, D. Bloch, M. Doherty +13 more
2006Osteoarthritis and Cartilage130 citations Open access
Semantic Scholar
Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
K. Chapman, Zehra Mustafa, C. Irven, A. Carr +10 more
1999American Journal of Human Genetics129 citations Open access
Semantic Scholar
Recent advances in the genetic investigation of osteoarthritis.
C. Peach, A. Carr, J. Loughlin
2005Trends in Molecular Medicine123 citations Open access
Semantic Scholar
The assessment of early osteoarthritis.
T. Pollard, S. Gwilym, A. Carr
2008Journal of Bone and Joint Surgery-british Volume115 citations
Semantic Scholar
Genetic influences in end-stage osteoarthritis. Sibling risks of hip and knee replacement for idiopathic osteoarthritis.
J. Chitnavis, J. Sinsheimer, K. Clipsham, J. Loughlin +3 more
1997Journal of Bone and Joint Surgery-british Volume115 citations Open access
Semantic Scholar
Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium
H. Kerkhof, I. Meulenbelt, T. Akune, N. Arden +46 more
2010Osteoarthritis and Cartilage102 citations Open access
Semantic Scholar
Patients with primary osteoarthritis show no change with ageing in the number of osteogenic precursors.
R. Oreffo, A. Bennett, A. Carr, J. Triffitt
1998Scandinavian Journal of Rheumatology101 citations
Semantic Scholar
GENETIC INFLUENCES IN END-STAGE OSTEOARTHRITIS: SIBLING RISKS OF HIP AND KNEE REPLACEMENT FOR IDIOPATHIC OSTEOARTHRITIS
J. Chitnavis, J. Sinsheimer, K. Clipsham, J. Loughlin +3 more
199790 citations
Semantic Scholar
Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.
Zehra Mustafa, B. Dowling, K. Chapman, J. Sinsheimer +2 more
2005Arthritis & Rheumatism89 citations Open access
Semantic Scholar
Linkage analysis of candidate genes as susceptibility loci for osteoarthritis-suggestive linkage of COL9A1 to female hip osteoarthritis.
Zehra Mustafa, K. Chapman, C. Irven, A. Carr +8 more
2000Rheumatology89 citations Open access
Semantic Scholar
Association analysis of the vitamin D receptor gene, the type I collagen gene COL1A1, and the estrogen receptor gene in idiopathic osteoarthritis.
J. Loughlin, J. Sinsheimer, Zehra Mustafa, A. Carr +6 more
2000Journal of Rheumatology84 citations
Semantic Scholar
Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate.
Yun Zhang, K. Johnson, R. G. G. Russell, Bryan Paul Wordsworth +3 more
2005Arthritis & Rheumatism83 citations
Semantic Scholar
Stratification analysis of an osteoarthritis genome screen-suggestive linkage to chromosomes 4, 6, and 16.
J. Loughlin, Zehra Mustafa, C. Irven, Anne Smith +3 more
1999American Journal of Human Genetics81 citations Open access
Semantic Scholar
Refinement of the chromosome 5p locus for familial calcium pyrophosphate dihydrate deposition disease.
L. Andrew, V. Brancolini, L. S. de la Peña, M. Devoto +17 more
1999American Journal of Human Genetics65 citations Open access
Semantic Scholar
Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations.
I. Meulenbelt, K. Chapman, R. Dieguez‐Gonzalez, D. Shi +14 more
2009Human Molecular Genetics63 citations Open access
Semantic Scholar
Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility
I. Meulenbelt, S. Bos, K. Chapman, R. van der Breggen +8 more
2010Annals of the Rheumatic Diseases59 citations Open access
Semantic Scholar
Extreme context specificity in differential allelic expression.
J. Wilkins, L. Southam, A. Price, Zehra Mustafa +2 more
2007Human Molecular Genetics59 citations Open access
Semantic Scholar
A Genome-Wide Association Study Identifies an Osteoarthritis Susceptibility Locus on Chromosome 7 q 22
H. Kerkhof, R. Lories, I. Meulenbelt, I. Jónsdóttir +38 more
201057 citations
Semantic Scholar
Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data
K. Elliott, K. Chapman, A. Day-Williams, K. Panoutsopoulou +20 more
2012Annals of the Rheumatic Diseases55 citations Open access
Semantic Scholar
The CALM1 core promoter polymorphism is not associated with hip osteoarthritis in a United Kingdom Caucasian population.
J. Loughlin, J. Sinsheimer, A. Carr, K. Chapman
2006Osteoarthritis and Cartilage53 citations Open access
Semantic Scholar
Assessment of the Lequesne index of severity for osteoarthritis of the hip in an elderly population.
J. Dawson, L. Linsell, H. Doll, K. Zondervan +4 more
2005Osteoarthritis and Cartilage47 citations Open access
Semantic Scholar
Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti–Cyclic Citrullinated Peptide–Negative Rheumatoid Arthritis
S. Viatte, J. Massey, J. Bowes, K. Duffus +18 more
2016Arthritis & Rheumatology45 citations Open access
Semantic Scholar
Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study.
J. Riancho, C. García-Ibarbia, A. Gravani, E. V. Raine +11 more
2010Osteoarthritis and Cartilage44 citations Open access
Semantic Scholar
The effect of genome-wide association scan quality control on imputation outcome for common variants
L. Southam, K. Panoutsopoulou, N. W. Rayner, K. Chapman +16 more
2011European Journal of Human Genetics41 citations Open access
Semantic Scholar
Microsatellite association mapping of a primary osteoarthritis susceptibility locus on chromosome 6p12.3-q13.
L. Southam, B. Dowling, A. Ferreira, Lucy Marcelline +5 more
2004Arthritis & Rheumatism39 citations Open access
Semantic Scholar
Identification of five novel mutations in cartilage oligomeric matrix protein gene in pseudoachondroplasia and multiple epiphyseal dysplasia
J. Loughlin, C. Irven, Zehra Mustafa, Michael D. Briggs +5 more
1998Human Mutation39 citations Open access
Semantic Scholar
A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation
C. Esapa, Tertius A. Hough, S. Testori, R. Head +18 more
2012Journal of Bone and Mineral Research34 citations Open access
Semantic Scholar
Differential allelic expression of the type II collagen gene (COL2A1) in osteoarthritic cartilage.
J. Loughlin, Catherine Irven, N. Athanasou, A. Carr +1 more
1995American Journal of Human Genetics34 citations
Semantic Scholar
A Mouse with an N-Ethyl-N-Nitrosourea (ENU) Induced Trp589Arg Galnt3 Mutation Represents a Model for Hyperphosphataemic Familial Tumoural Calcinosis
C. Esapa, R. Head, J. Jeyabalan, H. Evans +10 more
2012PLoS ONE33 citations Open access
Semantic Scholar
Cuff Tear Arthropathy: Evidence of Functional Variation in Pyrophosphate Metabolism Genes
C. Peach, Yun Zhang, J. Dunford, Matthew A. Brown +1 more
2007Clinical Orthopaedics and Related Research33 citations
Semantic Scholar
Genetic Background Increases the Risk of Hip Osteoarthritis
Jonathan Spencer, J. Loughlin, K. Clipsham, A. Carr
2005Clinical Orthopaedics and Related Research33 citations Open access
Semantic Scholar
GAIN OF FUNCTION ANKH VARIANTS CAUSE BOTH FAMILIAL AND SPORADIC CALCIUM PYROPHOSPHATE DIHYDRATE CHONDROCALCINOSIS
Y. Zhang, K. Johnson, G. Russell, B. Wordsworth +3 more
200431 citations
Semantic Scholar
Finer linkage mapping of primary hip osteoarthritis susceptibility on chromosome 11q in a cohort of affected female sibling pairs.
K. Chapman, Zehra Mustafa, B. Dowling, L. Southam +2 more
2002Arthritis & Rheumatism31 citations Open access
Semantic Scholar
Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus.
A. Dodd, C. Rodriguez-Fontenla, M. Calaza, A. Carr +5 more
2011Osteoarthritis and Cartilage27 citations Open access
Semantic Scholar
Genetic association analysis of LRCH1 as an osteoarthritis susceptibility locus.
Sarah J B Snelling, J. Sinsheimer, A. Carr, J. Loughlin
2006Rheumatology25 citations Open access
Semantic Scholar

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