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C. Lagrasta · SciRah

Researcher profile · Semantic Scholar

C. Lagrasta

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C. Lagrasta — researcher profile on SciRah

h-index: 35
Works: 152
Citations: 4,956

Most-cited papers

Low PD-1 Expression in Cytotoxic CD8+ Tumor-Infiltrating Lymphocytes Confers an Immune-Privileged Tissue Microenvironment in NSCLC with a Prognostic and Predictive Value
G. Mazzaschi, D. Madeddu, A. Falco, G. Bocchialini +17 more
2017Clinical Cancer Research204 citations Open access
Semantic Scholar
Nerve Growth Factor Promotes Cardiac Repair following Myocardial Infarction
M. Meloni, A. Caporali, G. Graiani, C. Lagrasta +7 more
2010Circulation Research192 citations Open access
Semantic Scholar
Comparison of HER2 status in primary and paired metastatic sites of gastric carcinoma
C. Bozzetti, F. Negri, C. Lagrasta, P. Crafa +10 more
2011British Journal of Cancer152 citations Open access
Semantic Scholar
L718Q Mutation as New Mechanism of Acquired Resistance to AZD9291 in EGFR-Mutated NSCLC.
M. Bersanelli, R. Minari, P. Bordi, L. Gnetti +8 more
2016Journal of Thoracic Oncology146 citations Open access
Semantic Scholar
Human cardiac and bone marrow stromal cells exhibit distinctive properties related to their origin.
A. Rossini, C. Frati, C. Lagrasta, G. Graiani +16 more
2011Cardiovascular Research121 citations Open access
Semantic Scholar
Resident cardiac stem cells.
C. Frati, M. Savi, G. Graiani, C. Lagrasta +18 more
2011Current pharmaceutical design87 citations
Semantic Scholar
PTEN status in advanced colorectal cancer treated with cetuximab
F. Negri, C. Bozzetti, C. Lagrasta, P. Crafa +4 more
2009British Journal of Cancer86 citations Open access
Semantic Scholar
Predictors of gefitinib outcomes in advanced non-small cell lung cancer (NSCLC): study of a comprehensive panel of molecular markers.
M. Tiseo, G. Rossi, M. Capelletti, G. Sartori +11 more
2010Lung Cancer78 citations
Semantic Scholar
Resveratrol Treatment Reduces Cardiac Progenitor Cell Dysfunction and Prevents Morpho-Functional Ventricular Remodeling in Type-1 Diabetic Rats
F. Delucchi, R. Berni, C. Frati, S. Cavalli +10 more
2012PLoS ONE77 citations Open access
Semantic Scholar
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR‐Activating Mutation
S. La Monica, D. Madeddu, M. Tiseo, Valentina Vivo +14 more
2016Journal of Thoracic Oncology72 citations Open access
Semantic Scholar
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance
D. Cretella, F. Saccani, F. Quaini, C. Frati +12 more
2014Molecular Cancer65 citations Open access
Semantic Scholar
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC
S. La Monica, R. Minari, D. Cretella, L. Flammini +15 more
2019Journal of experimental & clinical cancer research : CR58 citations Open access
Semantic Scholar
ALK and ROS1 rearrangements tested by fluorescence in situ hybridization in cytological smears from advanced non‐small cell lung cancer patients
C. Bozzetti, R. Nizzoli, M. Tiseo, A. Squadrilli +13 more
2015Diagnostic Cytopathology43 citations
Semantic Scholar
Reduction of Myocardial Ischemia–Reperfusion Injury by Inhibiting Interleukin-1 Alpha
A. Mauro, E. Mezzaroma, J. Torrado, Priyanka Kundur +6 more
2017Journal of Cardiovascular Pharmacology42 citations
Semantic Scholar
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations
M. Bonelli, A. Cavazzoni, F. Saccani, R. Alfieri +14 more
2015Molecular Cancer Therapeutics38 citations
Semantic Scholar
Growth Factor-Induced Mobilization of Cardiac Progenitor Cells Reduces the Risk of Arrhythmias, in a Rat Model of Chronic Myocardial Infarction
L. Bocchi, M. Savi, G. Graiani, S. Rossi +13 more
2011PLoS ONE38 citations Open access
Semantic Scholar
Concurrent Acquired BRAF V600E Mutation and MET Amplification as Resistance Mechanism of First-Line Osimertinib Treatment in a Patient with EGFR-Mutated NSCLC.
R. Minari, P. Bordi, S. La Monica, A. Squadrilli +9 more
2018Journal of Thoracic Oncology37 citations Open access
Semantic Scholar
Integrated CT imaging and tissue immune features disclose a radio-immune signature with high prognostic impact on surgically resected NSCLC.
G. Mazzaschi, G. Milanese, P. Pagano, D. Madeddu +13 more
2020Lung Cancer35 citations
Semantic Scholar
High‐resolution X‐ray microtomography for three‐dimensional imaging of cardiac progenitor cell homing in infarcted rat hearts
A. Giuliani, C. Frati, A. Rossini, V. Komlev +7 more
2011Journal of Tissue Engineering and Regenerative Medicine33 citations Open access
Semantic Scholar
Characterization of ABC Transporters in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium
B. M. Rotoli, A. Barilli, R. Visigalli, F. Ferrari +6 more
2020International Journal of Molecular Sciences27 citations Open access
Semantic Scholar
Cancer treatment-induced cardiotoxicity: a cardiac stem cell disease?
Lucia Prezioso, S. Tanzi, F. Galaverna, C. Frati +18 more
2010Cardiovascular & Hematological Agents in Medicinal Chemistry27 citations
Semantic Scholar
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN
A. Cavazzoni, S. La Monica, R. Alfieri, A. Ravelli +14 more
2017OncoTarget26 citations Open access
Semantic Scholar
Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth
M. Chiu, G. Taurino, M. Bianchi, L. Ottaviani +5 more
2018International Journal of Molecular Sciences25 citations Open access
Semantic Scholar
Cardiac Regeneration and Repair : Mechanisms and Therapy Antiarrhythmic effect of growth factor-supplemented cardiac progenitor cells in chronic infarcted heart
M. Savi, L. Bocchi, S. Rossi, C. Frati +12 more
201625 citations
Semantic Scholar
Spatial architecture of tumour-infiltrating lymphocytes as a prognostic parameter in resected non-small-cell lung cancer.
G. Bocchialini, C. Lagrasta, D. Madeddu, G. Mazzaschi +12 more
2020European Journal of Cardio-Thoracic Surgery22 citations
Semantic Scholar
Development of Biomimetic Alginate/Gelatin/Elastin Sponges with Recognition Properties toward Bioactive Peptides for Cardiac Tissue Engineering
E. Rosellini, D. Madeddu, N. Barbani, C. Frati +5 more
2020Biomimetics20 citations Open access
Semantic Scholar
Imatinib mesylate‐induced cardiomyopathy involves resident cardiac progenitors
M. Savi, C. Frati, S. Cavalli, G. Graiani +15 more
2018Pharmacological Research17 citations
Semantic Scholar
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro.
B. Lorusso, G. Cerasoli, A. Falco, C. Frati +12 more
2022Vascular pharmacology16 citations Open access
Semantic Scholar
Parenchymal and Stromal Cells Contribute to Pro-Inflammatory Myocardial Environment at Early Stages of Diabetes: Protective Role of Resveratrol
M. Savi, L. Bocchi, R. Sala, C. Frati +10 more
2016Nutrients16 citations Open access
Semantic Scholar
Emergence of a HER2-amplified clone during disease progression in an ALK-rearranged NSCLC patient treated with ALK-inhibitors: a case report
R. Minari, L. Gnetti, C. Lagrasta, A. Squadrilli +8 more
2020Translational Lung Cancer Research15 citations Open access
Semantic Scholar
High levels of Notch intracellular cleaved domain are associated with stemness and reduced bevacizumab efficacy in patients with advanced colon cancer.
F. Negri, C. Bozzetti, G. Pedrazzi, C. Azzoni +14 more
2019Oncology Report15 citations Open access
Semantic Scholar
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method
C. Bozzetti, F. Quaini, A. Squadrilli, M. Tiseo +21 more
2015PLoS ONE15 citations Open access
Semantic Scholar
Development and validation of an high performance liquid chromatography-tandem mass spectrometry method for the determination of imatinib in rat tissues.
F. Bianchi, E. Caffarri, S. Cavalli, C. Lagrasta +3 more
2013Journal of Pharmaceutical and Biomedical Analysis15 citations
Semantic Scholar
Inhibition of Human Malignant Pleural Mesothelioma Growth by Mesenchymal Stromal Cells
V. Coccè, S. La Monica, M. Bonelli, G. Alessandri +15 more
2021Cells13 citations Open access
Semantic Scholar
Afatinib therapy in case of EGFR G724S emergence as resistance mechanism to osimertinib
R. Minari, A. Leonetti, L. Gnetti, T. Zielli +7 more
2021Anti-Cancer Drugs12 citations
Semantic Scholar
IGF-1 loaded injectable microspheres for potential repair of the infarcted myocardium
E. Rosellini, N. Barbani, C. Frati, D. Madeddu +9 more
2020Journal of Biomaterials Applications12 citations Open access
Semantic Scholar
Lung mesenchymal cells function as an inductive microenvironment for human lung cancer propagating cells†.
L. Ampollini, D. Madeddu, A. Falco, C. Frati +15 more
2014European Journal of Cardio-Thoracic Surgery12 citations Open access
Semantic Scholar
Involvement of HER-2/neu and metastasis-related proteins in the development of ileal neuroendocrine tumors
C. Azzoni, L. Bottarelli, Stefano Cecchini, C. Lagrasta +5 more
2011Virchows Archiv12 citations
Semantic Scholar
The role of pulmonary vascular endothelium in chronic obstructive pulmonary disease (COPD): Does endothelium play a role in the onset and progression of COPD?
S. Siragusa, G. Natali, A. Nogara, Marcello Trevisani +2 more
2023Exploration of Medicine11 citations Open access
Semantic Scholar
Blood and lymphatic vessels contribute to the impact of the immune microenvironment on clinical outcome in non-small-cell lung cancer†
G. Armani, D. Madeddu, G. Mazzaschi, G. Bocchialini +17 more
2018European Journal of Cardio-Thoracic Surgery11 citations Open access
Semantic Scholar
Strong Notch activation hinders bevacizumab efficacy in advanced colorectal cancer.
F. Negri, P. Crafa, G. Pedrazzi, C. Bozzetti +17 more
2015Future Oncology11 citations
Semantic Scholar
Isolation and Characterization of Human Lung Lymphatic Endothelial Cells
B. Lorusso, A. Falco, D. Madeddu, C. Frati +12 more
2015BioMed Research International11 citations Open access
Semantic Scholar
Genetics of Darier’s Disease: New Insights into Pathogenic Mechanisms
Barbara Moschella, Sabrina Busciglio, Enrico Ambrosini, Sofia Cesarini +27 more
2025Genes10 citations Open access
Semantic Scholar
GCN5 contributes to intracellular lipid accumulation in human primary cardiac stromal cells from patients affected by Arrhythmogenic cardiomyopathy
C. Volani, A. Pagliaro, Johannes Rainer, G. Paglia +25 more
2022Journal of Cellular and Molecular Medicine10 citations Open access
Semantic Scholar
Influence of injectable microparticle size on cardiac progenitor cell response
E. Rosellini, N. Barbani, C. Frati, D. Madeddu +8 more
2018Journal of Applied Biomaterials & Functional Materials10 citations Open access
Semantic Scholar
Time-course transcriptome analysis of a double challenge bleomycin-induced lung fibrosis rat model uncovers ECM homoeostasis-related translationally relevant genes
M. Bonatti, V. Pitozzi, P. Caruso, S. Pontis +11 more
2023BMJ Open Respiratory Research9 citations Open access
Semantic Scholar
Cardioprotection by Targeting the Pool of Resident and Extracardiac Progenitors.
K. Urbanek, C. Frati, G. Graiani, D. Madeddu +15 more
2015Current Drug Targets9 citations
Semantic Scholar
Validation of a radiomic approach to decipher NSCLC immune microenvironment in surgically resected patients
F. Trentini, G. Mazzaschi, G. Milanese, Claudio Pavone +13 more
2021Tumori8 citations Open access
Semantic Scholar
Optimizing PD-L1 evaluation on cytological samples from advanced non-small-cell lung cancer.
C. Bozzetti, A. Squadrilli, R. Nizzoli, C. Lagrasta +11 more
2020Immunotherapy8 citations
Semantic Scholar
Is Cytology Reliable for Epidermal Growth Factor Receptor Gene Evaluation in Non-small Cell Lung Cancer?
C. Bozzetti, M. Tiseo, C. Lagrasta, R. Nizzoli +4 more
2010Journal of Thoracic Oncology8 citations Open access
Semantic Scholar

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C. Frati×28
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