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R. Mdachi · SciRah

Researcher profile · Semantic Scholar

R. Mdachi

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R. Mdachi — researcher profile on SciRah

h-index: 11
Works: 31
Citations: 385

Most-cited papers

Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis.
J. Thuita, Simon Karanja, T. Wenzler, R. Mdachi +4 more
2008Acta Tropica97 citations
Semantic Scholar
Haematology of experimental Trypanosoma brucei rhodesiense infection in vervet monkeys
J. Kagira, J. Thuita, M. Ngotho, R. Mdachi +2 more
200853 citations Open access
Semantic Scholar
Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis
J. Thuita, M. Z. Wang, J. Kagira, C. Denton +8 more
2012PLoS Neglected Tropical Diseases39 citations Open access
Semantic Scholar
Efficacy of the Novel Diamidine Compound 2,5-Bis(4-Amidinophenyl)- Furan-Bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense Infection in Vervet Monkeys after Oral Administration
R. Mdachi, J. Thuita, J. Kagira, J. M. Ngotho +5 more
2008Antimicrobial Agents and Chemotherapy36 citations Open access
Semantic Scholar
Disposition of diminazene aceturate (Berenil) in trypanosome-infected pregnant and lactating cows.
R. Mdachi, G. Murilla, J. Omukuba, V. Cagnolati
1995Veterinary parasitology25 citations
Semantic Scholar
Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis
J. Thuita, K. K. Wolf, G. Murilla, Qiang Liu +12 more
2013PLoS Neglected Tropical Diseases21 citations Open access
Semantic Scholar
Rapid method for the assessment of trypanocidal drug resistance in the field
M. Eisler, J. Mcdermott, R. Mdachi, G. Murilla +11 more
200017 citations
Semantic Scholar
A competitive enzyme-linked immunosorbent assay for diminazene.
W. Karanja, R. Mdachi, G. Murilla
2002Acta Tropica13 citations
Semantic Scholar
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model
K. Ndung'u, G. Murilla, J. Thuita, G. Ngae +6 more
2020bioRxiv12 citations Open access
Semantic Scholar
Bioavailability, pharmacokinetics, and tissue distribution of 14C homidium after parenteral administration to Boran cattle.
G. Murilla, R. Mdachi, A. A. Ismail, W. Karanja
1996Journal of Veterinary Pharmacology and Therapeutics12 citations
Semantic Scholar
Aggravation of pathogenesis mediated by ochratoxin A in mice infected with Trypanosoma brucei rhodesiense
J. Kibugu, J. Ngeranwa, J. Makumi, J. Gathumbi +4 more
2009Parasitology11 citations
Semantic Scholar
Variation of sensitivity of Trypanosoma evansi isolates from Isiolo and Marsabit counties of Kenya to locally available trypanocidal drugs
R. Mdachi, K. Ogolla, J. Auma, F. Wamwiri +7 more
2023PLoS ONE10 citations Open access
Semantic Scholar
Coenzyme Q_10 prevented Trypanosoma brucei rhodesiense-mediated breach of the blood brain barrier, inflammation and organ damage in late stage of Human African Trypanosomiasis
Lynn Kitwan, Celestine Makobe, R. Mdachi, Dawn Maranga +2 more
2022Journal of Parasitic Diseases9 citations Open access
Semantic Scholar
Pharmacokinetics, bioavailability and tissue residues of [14C]isometamidium in non-infected and Trypanosoma congolense-infected Boran cattle.
G. Murilla, R. Mdachi, W. Karanja
1996Acta Tropica6 citations
Semantic Scholar
Improved Sample Selection and Preparation Methods for Sampling Plans Used to Facilitate Rapid and Reliable Estimation of Aflatoxin in Chicken Feed
J. Kibugu, R. Mdachi, L. Munga, D. Mburu +4 more
2021Toxins5 citations Open access
Semantic Scholar
Comparative pathogenicity of Trypanosoma brucei rhodesiense strains in Swiss white mice and Mastomys natalensis rats.
M. W. Muchiri, K. Ndung'u, J. Kibugu, J. Thuita +4 more
2015Acta Tropica5 citations
Semantic Scholar
Spatial–Temporal Variations in Parasitological Prevalence and Host-Related Risk Factors of Camel Trypanosomiasis and Its Vectors in North Eastern Kenya: A Repeated Cross-Sectional Study
K. Ogolla, J. Chemuliti, F. Wamwiri, J. Auma +7 more
2023Journal of Parasitology Research3 citations Open access
Semantic Scholar
Molecular Identification of African Trypanosome Stabilates from Livestock in Lamu County, Kenya
Miriam Gathogo, P. Mukiria, J. Thuita, V. Adunga +6 more
20173 citations
Semantic Scholar
Short Communication Report: Evaluation of Indirect Enzyme-Linked Immunosorbent Assay (ELISA) systems for the serodiagnosis of bovine trypanosomosis in disease endemic areas of Kenya
J. Ouma, J. M. Mwangi, R. Mdachi, G. Murilla
2010The Scientific World Journal3 citations Open access
Semantic Scholar
In vitro Antiplasmodial Activities of Crude Extracts and Compounds Derived from Selected Indigenous Medicinal Plants used Traditionally to Treat Malaria in Kenya
S. Guya, E. Njagi, A. Guantai, C. C. Lang'at-Thoruwa +6 more
2022Journal of Scientific Research and Reports2 citations Open access
Semantic Scholar
Risk of Environmental Chemical Contaminants Associated with Animal Feeding in Peri Urban Areas of Kisumu Town
C. M. Inyagwa, K. Orengo, P. Amanya, R. Mdachi
2022International Journal of Current Microbiology and Applied Sciences1 citations Open access
Semantic Scholar
Pharmacokinetics of Chloramphenicol in Sheep after Intramuscular Administration
J. O. Wesongah, G. Murilla, A. Guantai, R. Mdachi
20101 citations
Semantic Scholar
Evaluation of Indirect Enzyme-Linked Immunosorbent Assay (ELISA) Systems for the Serodiagnosis of Bovine Trypanosomosis in Disease Endemic Areas of Kenya
J. Ouma, J. M. Mwangi, R. Mdachi, G. Murilla
20071 citations
Semantic Scholar
The pathogenicity of blood stream and central nervous system forms of Trypanosoma brucei rhodesiense trypanosomes in laboratory mice: a comparative study
K. Ndungu, J. Thuita, G. Murilla, J. Kagira +7 more
2022F1000Research0 citations Open access
Semantic Scholar
Risk Factors Associated with Livestock Feeding and Disease Control Practices in the Peri-Urban Slums of Kisumu City, Kenya
C. M. Inyagwa, Wekesa Sabesia, K. Orengo, P. Amanya +1 more
2020International Journal of Innovative Research & Development0 citations Open access
Semantic Scholar
Epidemiological Evaluation of Trypanosomiasis Control in Cattle
R. Mdachi
20140 citations
Semantic Scholar
Heavy metal contents of Azidirachta indica collected from Akungba- Akoko (Nigeria)
J. Kibugu, R. Mdachi, J. N. Makumi, Joseph J. N. Ngeran +2 more
20100 citations
Semantic Scholar
A competitive enzyme linked immunosorbent assay for the determination of diminazene residues in animal tissues.
W. Karanja, R. Mdachi, J. Ngeranwa, J. Murungi
20100 citations Open access
Semantic Scholar
Improved survival of laboratory-reared tsetse flies Glossina morsitans morsitans (Diptera: Glossinidae) through use of homidium bromide-treated blood diet
J. Kibugu, J. N. Mwangi, J. M. Kiragu, M. W. Muchiri +2 more
20100 citations
Semantic Scholar
Efﬁcacy of the Novel Diamidine Compound 2,5-Bis(4-Amidinophenyl)-Furan-Bis- O -Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense Infection in Vervet Monkeys after Oral Administration (cid:1)
R. Mdachi, J. Thuita, J. Kagira, J. M. Ngotho +5 more
20090 citations
Semantic Scholar
The pathogenicity of blood stream and central nervous system forms of Trypanosoma brucei rhodesiense trypanosomes in laboratory mice: a comparative study [version 1; peer review: 2 approved with reservations]
K. Ndung'u, J. Thuita, G. Murilla, J. Kagira +7 more
0 citations
Semantic Scholar

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