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R. Dearman · SciRah

Researcher profile · Semantic Scholar

R. Dearman

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R. Dearman — researcher profile on SciRah

h-index: 76
Works: 433
Citations: 19K

Most-cited papers

Immunogenicity of therapeutic proteins: Influence of aggregation
Kirsty D. Ratanji, J. Derrick, R. Dearman, I. Kimber
2013Journal of Immunotoxicology514 citations Open access
Semantic Scholar
Tartrate resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature
T. Briggs, G. Rice, Sarah B. Daly, J. Urquhart +36 more
2011Nature Genetics253 citations Open access
Semantic Scholar
An assessment of the ability of phthalates to influence immune and allergic responses.
I. Kimber, R. Dearman
2010Toxicology194 citations
Semantic Scholar
Chemical allergy: translating biology into hazard characterization.
I. Kimber, D. Basketter, G. Gerberick, C. Ryan +1 more
2011Toxicological Sciences169 citations
Semantic Scholar
The effect of arginine glutamate on the stability of monoclonal antibodies in solution
Priscilla Kheddo, Malgorzata B. Tracka, J. Armer, R. Dearman +3 more
2014International journal of pharmaceutics84 citations Open access
Semantic Scholar
The direct peptide reactivity assay: selectivity of chemical respiratory allergens.
Jon F. Lalko, I. Kimber, G. Gerberick, L. Foertsch +2 more
2012Toxicological Sciences73 citations Open access
Semantic Scholar
Chemical respiratory allergy: reverse engineering an adverse outcome pathway.
I. Kimber, R. Dearman, D. Basketter, D. Boverhof
2014Toxicology72 citations Open access
Semantic Scholar
Chemical reactivity measurements: potential for characterization of respiratory chemical allergens.
J. Lalko, I. Kimber, R. Dearman, G. Gerberick +2 more
2011Toxicology in Vitro58 citations
Semantic Scholar
Why does allergic contact dermatitis exist?
J. Mcfadden, P. Puangpet, D. Basketter, R. Dearman +1 more
2013British Journal of Dermatology54 citations
Semantic Scholar
Dendritic Cell IL-1α and IL-1β Are Polyubiquitinated and Degraded by the Proteasome
Joseph S. Ainscough, G. Gerberick, Maryam Zahedi-Nejad, G. López-Castejón +3 more
2014Journal of Biological Chemistry52 citations Open access
Semantic Scholar
Danger, intracellular signaling, and the orchestration of dendritic cell function in skin sensitization
Joseph S. Ainscough, G. Gerberick, R. Dearman, I. Kimber
2013Journal of Immunotoxicology47 citations Open access
Semantic Scholar
Allergic contact dermatitis: a commentary on the relationship between T lymphocytes and skin sensitising potency.
I. Kimber, G. Maxwell, N. Gilmour, R. Dearman +2 more
2012Toxicology46 citations
Semantic Scholar
Inter‐relationships between different classes of chemical allergens
R. Dearman, D. Basketter, I. Kimber
2013Journal of Applied Toxicology44 citations
Semantic Scholar
Lower levels of interleukin‐1β gene expression are associated with impaired Langerhans’ cell migration in aged human skin
S. Pilkington, S. Ogden, L. Eaton, R. Dearman +2 more
2017Immunology43 citations Open access
Semantic Scholar
Differential immunogenicity and allergenicity of native and recombinant human lactoferrins: Role of glycosylation
R. Almond, B. Flanagan, A. Antonopoulos, S. Haslam +3 more
2013European Journal of Immunology43 citations Open access
Semantic Scholar
Extra domain A-positive fibronectin-positive feedback loops and their association with cutaneous inflammatory disease.
J. McFadden, D. Basketter, R. Dearman, I. Kimber
2011Clinical Dermatology43 citations
Semantic Scholar
The Hapten‐Atopy hypothesis II: the ‘cutaneous hapten paradox’
J. Mcfadden, R. Dearman, J. M. L. White, D. Basketter +1 more
2011Clinical and Experimental Allergy41 citations
Semantic Scholar
Editor’s Highlight: Subvisible Aggregates of Immunogenic Proteins Promote a Th1-Type Response
Kirsty D. Ratanji, R. Dearman, I. Kimber, R. Thorpe +2 more
2016Toxicological Sciences39 citations Open access
Semantic Scholar
Chemical allergens--what are the issues?
I. Kimber, D. Basketter, R. Dearman
2010Toxicology37 citations
Semantic Scholar
Peanut sensitisation and allergy: influence of early life exposure to peanuts
Rachel L. Thompson, L. Miles, J. Lunn, G. Devereux +3 more
2010British Journal of Nutrition34 citations Open access
Semantic Scholar
Impaired Langerhans cell migration in psoriasis is due to an altered keratinocyte phenotype induced by interleukin‐17
L. Eaton, Kieran T. Mellody, S. Pilkington, R. Dearman +2 more
2018British Journal of Dermatology33 citations Open access
Semantic Scholar
Immunoregulation of skin sensitization and regulatory T cells
I. Kimber, M. Travis, Stefan F. Martin, R. Dearman
2012Contact Dermatitis33 citations Open access
Semantic Scholar
Reactivity of chemical respiratory allergens in the Peroxidase Peptide Reactivity Assay.
J. Lalko, R. Dearman, G. Gerberick, J. Troutman +2 more
2013Toxicology in Vitro32 citations
Semantic Scholar
The effect of ageing on phenotype and function of monocyte-derived Langerhans cells
S. Ogden, R. Dearman, I. Kimber, C. Griffiths
2011British Journal of Dermatology32 citations Open access
Semantic Scholar
The lymphocyte transformation test in allergic contact dermatitis: New opportunities
A. Popple, Jason D. L. Williams, G. Maxwell, N. Gellatly +2 more
2016Journal of Immunotoxicology31 citations Open access
Semantic Scholar
Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization
I. Kimber, R. Dearman, D. Basketter
2014Journal of Applied Toxicology31 citations
Semantic Scholar
The Local Lymph Node Assay (LLNA)
C. Rovida, C. Ryan, S. Cinelli, D. Basketter +2 more
2012Current Protocols in Toxicology31 citations
Semantic Scholar
Relationship between protein digestibility and allergenicity: comparisons of pepsin and cathepsin.
Emily S. Foster, I. Kimber, R. Dearman
2013Toxicology30 citations
Semantic Scholar
Langerhans cell mobilization distinguishes between early-onset and late-onset psoriasis.
F. Shaw, M. Cumberbatch, C. E. Kleyn, R. Begum +3 more
2010Journal of Investigative Dermatology30 citations Open access
Semantic Scholar
Investigating Liquid-Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl.
Priscilla Kheddo, Jack E. Bramham, R. Dearman, Shahid Uddin +2 more
2017Molecular Pharmaceutics27 citations Open access
Semantic Scholar
The Aryl Hydrocarbon Receptor: Differential Contribution to T Helper 17 and T Cytotoxic 17 Cell Development
M. Hayes, Vitalijs Ovcinnikovs, Andrew G. Smith, I. Kimber +1 more
2014PLoS ONE27 citations Open access
Semantic Scholar
Human neutrophil antigens: Nature, clinical significance and detection
T. Browne, R. Dearman, A. Poles
2020International Journal of Immunogenetics26 citations Open access
Semantic Scholar
P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages
Pavlos C. Englezou, S. Rothwell, Joseph S. Ainscough, D. Brough +4 more
2015Cytokine25 citations Open access
Semantic Scholar
Proteomic and Bioinformatic Analyses for the Identification of Proteins With Low Allergenic Potential for Hazard Assessment.
N. Krutz, J. Winget, C. Ryan, R. Wimalasena +4 more
2019Toxicological Sciences22 citations
Semantic Scholar
Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies
S. Rane, R. Dearman, I. Kimber, Shahid Uddin +5 more
2019Pharmaceutical Research21 citations Open access
Semantic Scholar
Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin
Joseph S. Ainscough, G. Gerberick, I. Kimber, R. Dearman
2015Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Identification of B cell epitopes enhanced by protein unfolding and aggregation
Timothy J. Eyes, James I. Austerberry, R. Dearman, L. Johannissen +4 more
2019Molecular Immunology20 citations Open access
Semantic Scholar
Influence of Escherichia coli chaperone DnaK on protein immunogenicity
Kirsty D. Ratanji, J. Derrick, I. Kimber, R. Thorpe +2 more
2016Immunology20 citations Open access
Semantic Scholar
Treatment-Related Restoration of Langerhans Cell Migration in Psoriasis
F. Shaw, K. Mellody, S. Ogden, R. Dearman +2 more
2013Journal of Investigative Dermatology19 citations Open access
Semantic Scholar
The effects of arginine glutamate, a promising excipient for protein formulation, on cell viability: Comparisons with NaCl
Priscilla Kheddo, A. Golovanov, K. Mellody, Shahid Uddin +2 more
2016Toxicology in Vitro18 citations Open access
Semantic Scholar
Toxic shock syndrome: characterization of human immune responses to TSST-1 and evidence for sensitivity thresholds.
I. Kimber, Suba Nookala, Catherine C. Davis, G. Gerberick +9 more
2013Toxicological Sciences18 citations
Semantic Scholar
The selective peptide reactivity of chemical respiratory allergens under competitive and non-competitive conditions
J. Lalko, I. Kimber, R. Dearman, A. M. Api +1 more
2013Journal of Immunotoxicology18 citations Open access
Semantic Scholar
Langerhans cells express human β‐defensin 3: relevance for immunity during skin ageing
S. Pilkington, R. Dearman, I. Kimber, C. Griffiths
2018British Journal of Dermatology17 citations
Semantic Scholar
Anti‐hapten antibodies in response to skin sensitization
H. Singleton, A. Popple, N. Gellatly, G. Maxwell +4 more
2016Contact Dermatitis17 citations
Semantic Scholar
Butyl benzyl phthalate: effects on immune responses to ovalbumin in mice
R. Dearman, C. Betts, Lorna Beresford, Laura Bailey +2 more
2009Journal of Applied Toxicology17 citations
Semantic Scholar
The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors
Theres Oakes, A. Popple, Jason D. L. Williams, K. Best +7 more
2017Frontiers in Immunology16 citations Open access
Semantic Scholar
Skin sensitization induced Langerhans’ cell mobilization: variable requirements for tumour necrosis factor‐α
L. Eaton, R. Roberts, I. Kimber, R. Dearman +1 more
2015Immunology15 citations Open access
Semantic Scholar
Epicutaneous exposure to proteins and skin immune function
I. Kimber, C. Griffiths, D. Basketter, J. McFadden +1 more
2014EJD. European journal of dermatology15 citations
Semantic Scholar
ANNALS EXPRESS: The impact of the analytical performance specifications of calcium and albumin on adjusted calcium.
N. Jassam, Annette Thomas, K. Hayden, R. Dearman +1 more
2020Annals of Clinical Biochemistry14 citations
Semantic Scholar
The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies
S. Gurjar, Jun X. Wheeler, M. Wadhwa, R. Thorpe +4 more
2019Journal of Biological Chemistry13 citations Open access
Semantic Scholar

Frequent co-authors

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I. Kimber×39
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I. Kimber — researcher profile on SciRah
D. Basketter×10
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D. Basketter — researcher profile on SciRah
G. Gerberick×10
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G. Gerberick — researcher profile on SciRah
J. Derrick×6
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J. Derrick — researcher profile on SciRah

×5

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C. Griffiths — researcher profile on SciRah

Shahid Uddin×4

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Shahid Uddin — researcher profile on SciRah

Joseph S. Ainscough×4

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Joseph S. Ainscough — researcher profile on SciRah

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G. Maxwell — researcher profile on SciRah

Kirsty D. Ratanji×3

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Kirsty D. Ratanji — researcher profile on SciRah

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C. Ryan — researcher profile on SciRah

Priscilla Kheddo×3

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Priscilla Kheddo — researcher profile on SciRah

C. F. van der Walle×3

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C. F. van der Walle — researcher profile on SciRah