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Shahid Uddin · SciRah

Researcher profile · Semantic Scholar

Shahid Uddin

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Shahid Uddin — researcher profile on SciRah

h-index: 21
Works: 55
Citations: 1,500

Most-cited papers

The role of electrostatics in protein-protein interactions of a monoclonal antibody.
Dorota Roberts, R. Keeling, Malgorzata B. Tracka, C. F. van der Walle +3 more
2014Molecular Pharmaceutics176 citations
Semantic Scholar
Specific ion and buffer effects on protein-protein interactions of a monoclonal antibody.
Dorota Roberts, R. Keeling, Malgorzata B. Tracka, C. F. van der Walle +3 more
2015Molecular Pharmaceutics161 citations
Semantic Scholar
Determining Antibody Stability: Creation of Solid‐Liquid Interfacial Effects within a High Shear Environment
J. Biddlecombe, Alan Craig, Hu Zhang, Shahid Uddin +3 more
2007Biotechnology progress (Print)91 citations
Semantic Scholar
The effect of arginine glutamate on the stability of monoclonal antibodies in solution
Priscilla Kheddo, Malgorzata B. Tracka, J. Armer, R. Dearman +3 more
2014International journal of pharmaceutics84 citations Open access
Semantic Scholar
Factors influencing antibody stability at solid–liquid interfaces in a high shear environment
J. Biddlecombe, Graeme R. Smith, Shahid Uddin, S. Mulot +4 more
2009Biotechnology progress (Print)69 citations
Semantic Scholar
Adsorption behavior of a human monoclonal antibody at hydrophilic and hydrophobic surfaces
R. Couston, M. Skoda, Shahid Uddin, C. F. van der Walle
2013mAbs67 citations Open access
Semantic Scholar
The effect of charge mutations on the stability and aggregation of a human single chain Fv fragment
James I. Austerberry, R. Dajani, Stanislava Panova, Dorota Roberts +7 more
2017European journal of pharmaceutics and biopharmaceutics57 citations Open access
Semantic Scholar
A pH-Induced Switch in Human Glucagon-like Peptide-1 Aggregation Kinetics.
Karolina L Zapadka, Frederik J. Becher, Shahid Uddin, P. Varley +3 more
2016Journal of the American Chemical Society48 citations Open access
Semantic Scholar
Advancing therapeutic protein discovery and development through comprehensive computational and biophysical characterization.
Lorenzo Gentiluomo, Hristo L. Svilenov, Dillen Augustijn, Inas El Bialy +22 more
2019Molecular Pharmaceutics47 citations Open access
Semantic Scholar
Characterizing monoclonal antibody formulations in arginine glutamate solutions using 1H NMR spectroscopy
Priscilla Kheddo, M. Cliff, Shahid Uddin, C. F. van der Walle +1 more
2016mAbs44 citations Open access
Semantic Scholar
Rigidity Emerges during Antibody Evolution in Three Distinct Antibody Systems: Evidence from QSFR Analysis of Fab Fragments
Tong Li, Malgorzata B. Tracka, Shahid Uddin, J. Casas-Finet +2 more
2015PLoS Comput. Biol.43 citations Open access
Semantic Scholar
The effect of protein concentration on the viscosity of a recombinant albumin solution formulation
Andrea D. Gonçalves, C. Alexander, C. Roberts, S. G. Spain +2 more
201641 citations Open access
Semantic Scholar
The Effect of Lipidation on the Self-Assembly of the Gut-Derived Peptide Hormone PYY3-36.
Jessica A Hutchinson, Samuel Burholt, I. Hamley, Anna-Karin Lundbäck +5 more
2018Bioconjugate chemistry39 citations
Semantic Scholar
Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly
Myriam M. Ouberai, A. D. dos Santos, Sonja Kinna, S. Madalli +11 more
2017Nature Communications39 citations Open access
Semantic Scholar
Redistribution of Flexibility in Stabilizing Antibody Fragment Mutants Follows Le Châtelier’s Principle
Tong Li, Malgorzata B. Tracka, Shahid Uddin, J. Casas-Finet +2 more
2014PLoS ONE36 citations Open access
Semantic Scholar
Coarse-Grained Modeling of Antibodies from Small-Angle Scattering Profiles.
D. Corbett, M. Hebditch, R. Keeling, Peng Ke +8 more
2017Journal of Physical Chemistry B35 citations
Semantic Scholar
Understanding how charge and hydrophobicity influence globular protein adsorption to alkanethiol and material surfaces.
Simon J. Attwood, R. Kershaw, Shahid Uddin, Steven M. Bishop +1 more
2019Journal of materials chemistry. B33 citations Open access
Semantic Scholar
Antibody adsorption on the surface of water studied by neutron reflection
Charles Smith, Zongyi Li, R. Holman, F. Pan +9 more
2017mAbs32 citations Open access
Semantic Scholar
Neutron Reflection Study of Surface Adsorption of Fc, Fab, and the Whole mAb.
Zongyi Li, Ruiheng Li, Charles Smith, F. Pan +8 more
2017ACS Applied Materials and Interfaces30 citations Open access
Semantic Scholar
Investigating Liquid-Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl.
Priscilla Kheddo, Jack E. Bramham, R. Dearman, Shahid Uddin +2 more
2017Molecular Pharmaceutics27 citations Open access
Semantic Scholar
Determination of protein-protein interactions in a mixture of two monoclonal antibodies.
Priyanka Singh, Aisling Roche, C. F. van der Walle, Shahid Uddin +4 more
2019Molecular Pharmaceutics25 citations
Semantic Scholar
Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies
S. Rane, R. Dearman, I. Kimber, Shahid Uddin +5 more
2019Pharmaceutical Research21 citations Open access
Semantic Scholar
A novel combined strategy for the physical PEGylation of polypeptides.
E. Ambrosio, Michela Barattin, Sara Bersani, Saif Shubber +4 more
2016Journal of Controlled Release20 citations
Semantic Scholar
Characterisation of Stress-Induced Aggregate Size Distributions and Morphological Changes of a Bi-Specific Antibody Using Orthogonal Techniques.
Zahra Hamrang, Maryam Hussain, Katie Tingey, Malgorzata B. Tracka +4 more
2015Journal of Pharmacy and Science20 citations
Semantic Scholar
Modulation of the hydration water around monoclonal antibodies on addition of excipients detected by terahertz-time domain spectroscopy
V. Wallace, D. Ferachou, Peng Ke, Katie Day +5 more
2015International Conference on Infrared, Millimeter, and Terahertz Waves20 citations
Semantic Scholar
Evaluation of aggregate and silicone-oil counts in pre-filled siliconized syringes: An orthogonal study characterising the entire subvisible size range.
Maryam Shah, Z. Rattray, Katie Day, Shahid Uddin +3 more
2017International journal of pharmaceutics19 citations Open access
Semantic Scholar
Decomposing dynamical couplings in mutated scFv antibody fragments into stabilizing and destabilizing effects
Azhagiya Singam Ettayapuram Ramaprasad, Shahid Uddin, J. Casas-Finet, D. Jacobs
2017Journal of the American Chemical Society18 citations Open access
Semantic Scholar
The effects of arginine glutamate, a promising excipient for protein formulation, on cell viability: Comparisons with NaCl
Priscilla Kheddo, A. Golovanov, K. Mellody, Shahid Uddin +2 more
2016Toxicology in Vitro18 citations Open access
Semantic Scholar
Micro- and macro-viscosity relations in high concentration antibody solutions.
Maryam Shah, D. Corbett, A. Lanzaro, Aisling Roche +6 more
2020European journal of pharmaceutics and biopharmaceutics15 citations Open access
Semantic Scholar
Cluster Percolation Causes Shear Thinning Behavior in Concentrated Solutions of Monoclonal Antibodies.
A. Lanzaro, Aisling Roche, Nicole Sibanda, D. Corbett +8 more
2021Molecular Pharmaceutics14 citations Open access
Semantic Scholar
An Ultrasonic Line Follower Robot to Detect Obstacles and Edges for Industrial and Rescue Operations
Vicky Barua, Mohamad Arif, Shahid Uddin, Mithun Das +3 more
202014 citations Open access
Semantic Scholar
Mutations in Antibody Fragments Modulate Allosteric Response Via Hydrogen-Bond Network Fluctuations.
Amit Kumar Srivastava, Malgorzata B. Tracka, Shahid Uddin, J. Casas-Finet +2 more
2016Biophysical Journal14 citations Open access
Semantic Scholar
The effect of palmitoylation on the conformation and physical stability of a model peptide hormone.
E. Longo, E. De Santis, R. Hussain, C. F. van der Walle +4 more
2014International journal of pharmaceutics14 citations
Semantic Scholar
Interaction and destabilization of a monoclonal antibody and albumin to surfaces of varying functionality and hydrophobicity.
R. Couston, D. Lamprou, Shahid Uddin, C. F. van der Walle
2012International journal of pharmaceutics14 citations
Semantic Scholar
Determination of protein-protein interactions at high co-solvent concentrations using static and dynamic light scattering.
Luke Holloway, Aisling Roche, S. Marzouk, Shahid Uddin +3 more
2020Journal of Pharmacy and Science12 citations
Semantic Scholar
The Present and Future Role of Microfluidics for Protein and Peptide-Based Therapeutics and Diagnostics
E. Weaver, Shahid Uddin, D. Cole, Andrew Hooker +1 more
2021Applied Sciences11 citations Open access
Semantic Scholar
Application of ER Stress Biomarkers to Predict Formulated Monoclonal Antibody Stability.
N. Talbot, Emma J. Mead, S. Davies, Shahid Uddin +1 more
2019Biotechnology Journal7 citations Open access
Semantic Scholar
Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding.
A. Kulakova, Dillen Augustijn, Inas El Bialy, Lorenzo Gentiluomo +29 more
2023Molecular Pharmaceutics6 citations Open access
Semantic Scholar
Biotherapeutic protein formulation variables influence protein integrity and can promote post-translational modifications as shown using chicken egg white lysozyme as a model system
Evdoxia Gourbatsi, Jane F. Povey, Shahid Uddin, C. Smales
2015Biotechnology Letters6 citations Open access
Semantic Scholar
Emerging technologies for combating pandemics
E. Weaver, Shahid Uddin, D. Lamprou
2022Expert Review of Medical Devices5 citations Open access
Semantic Scholar
Dipicolinic acid as a novel spore-inspired excipient for antibody formulation.
I. Batalha, Peng Ke, E. Tejeda-Montes, Shahid Uddin +2 more
2017International journal of pharmaceutics5 citations Open access
Semantic Scholar
Chapter 25: Peptide Drug/Device Combinations
Shahid Uddin
2020Development of Biopharmaceutical Drug-Device Products2 citations
Semantic Scholar
Comparison the Effectiveness of Manual Therapy, Electrotherapy and Core Stability Exercise vs Electrotherapy, Traction and Traditional Exercise for Acute Low Back Pain
Dolilur Rahman, Israt Jahan, Shahid Uddin, Zakir Uddin +2 more
20152 citations Open access
Semantic Scholar
Single Point Mutations Modulate Dynamical Allostery in IgG4 Monoclonal Antibodies
L. Baker, Shahid Uddin, Azhagiya Singam, D. Jacobs +1 more
2019Biophysical Journal0 citations Open access
Semantic Scholar
Application of instrumental analysis methods to characterisation of monoclonal antibody-based formulations
Shahid Uddin
20190 citations
Semantic Scholar
The development of therapeutic proteins can be hindered by poor decision-making strategies in the early stage
Lorenzo Gentiluomo, Hristo L. Svilenov, M. Morales, A. Kulakova +19 more
20190 citations
Semantic Scholar
Achieving ultra high antibody concentrations
P. Davis, Maryam Hussain, A. Lanzaro, T. Jowitt +12 more
20170 citations
Semantic Scholar
Variable Dynamics of IgG4 Monoclonal Antibody Controlled by Single Point Mutations
Ettayapuram Ramaprasad Azhagiya Singam, Shahid Uddin, J. Casas-Finet, D. Jacobs
20170 citations Open access
Semantic Scholar
A pH-induced switch in GLP-1 aggregation kinetics
Karolina L Zapadka, Frederik J. Becher, Shahid Uddin, P. Varley +4 more
20160 citations
Semantic Scholar
Dynamic Characteristics of Allosteric Pathways in scFv Antibody Fragments
A. Srivastava, Malgorzata B. Tracka, Shahid Uddin, J. Casas-Finet +2 more
20150 citations Open access
Semantic Scholar

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