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M. Horner · SciRah

Researcher profile · Semantic Scholar

M. Horner

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M. Horner — researcher profile on SciRah

h-index: 15
Works: 22
Citations: 947

Most-cited papers

Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia.
W. Evans, M. Horner, Ya-Qin Chu, D. Kalwinsky +1 more
1991Jornal de Pediatria397 citations
Semantic Scholar
Alternative Strategies for Toxicity Testing of Species-Specific Biopharmaceuticals
J. Bussiere, Pauline L. Martin, M. Horner, Jessica A. Couch +4 more
2009International journal of toxicology85 citations
Semantic Scholar
Evaluation of the Renal Effects of an Antisense Phosphorothioate Oligodeoxynucleotide in Monkeys
D. Monteith, M. Horner, N. Gillett, M. Butler +4 more
1999Toxicologic pathology (Print)71 citations
Semantic Scholar
Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine.
Daniel B. Horne, Kaustav Biswas, James Brown, M. Bartberger +18 more
2018Journal of Medicinal Chemistry51 citations Open access
Semantic Scholar
Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5.
V. Cee, M. Frohn, B. Lanman, Jennifer E. Golden +21 more
2011ACS Medicinal Chemistry Letters50 citations Open access
Semantic Scholar
Homeostasis of Human NK Cells Is Not IL-15 Dependent
H. Lebrec, M. Horner, K. Gorski, Wayne H. Tsuji +10 more
2013Journal of Immunology42 citations Open access
Semantic Scholar
Pharmacokinetics and Tissue Disposition in Monkeys of an Antisense Oligonucleotide Inhibitor of Ha-Ras Encapsulated in Stealth Liposomes
R. Yu, R. Geary, J. Leeds, Tanya Watanabe +14 more
1999Pharmaceutical Research38 citations
Semantic Scholar
Pharmacokinetics and Urinary Excretion of Amikacin in Low-Clearance Unilamellar Liposomes after a Single or Repeated Intravenous Administration in the Rhesus Monkey
R. Fielding, L. Moon-Mcdermott, Ramilla O. Lewis, M. Horner
1999Antimicrobial Agents and Chemotherapy37 citations Open access
Semantic Scholar
Benzofuran Derivatives as Potent, Orally Active S1P1 Receptor Agonists: A Preclinical Lead Molecule for MS.
A. Saha, Xiang Yu, Jian Lin, M. Lobera +17 more
2011ACS Medicinal Chemistry Letters33 citations Open access
Semantic Scholar
Preclinical development of AMG 139, a human antibody specifically targeting IL‐23
K. Köck, Wei-Jian Pan, J. Gow, M. Horner +16 more
2015British Journal of Pharmacology29 citations Open access
Semantic Scholar
Ovarian Choriocarcinoma in a Rhesus Monkey Associated with Elevated Serum Chorionic Gonadotropin Levels
C. Farman, Kurt Benirschke, M. Horner, P. Lappin
2005Veterinary Pathology-Supplement20 citations Open access
Semantic Scholar
A novel assay to measure B cell responses to keyhole limpet haemocyanin vaccination in healthy volunteers and subjects with systemic lupus erythematosus
J. Ferbas, S. Belouski, M. Horner, A. Kaliyaperumal +8 more
2013British Journal of Clinical Pharmacology18 citations Open access
Semantic Scholar
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activity.
L. Pennington, Michael D Croghan, K. Sham, Alexander J. Pickrell +17 more
2012Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1.
L. Pennington, K. Sham, Alexander J. Pickrell, P. Harrington +16 more
2011ACS Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1).
B. Lanman, V. Cee, Srinivasa R Cheruku, M. Frohn +26 more
2011ACS Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Defining dose-response relationships in the therapeutic blockade of B7RP-1-dependent immune responses.
D. Metz, Deanna Mohn, Ming Zhang, Thomas P. Horan +12 more
2009European Journal of Pharmacology10 citations
Semantic Scholar
Safety toxicity study of plasmid‐based IL‐12 therapy in Cynomolgus monkeys
A. Quezada, M. Horner, D. Loera, M. French +5 more
2002The Journal of pharmacy and pharmacology8 citations Open access
Semantic Scholar
Safety Assessment Strategies and Predictive Safety of Biopharmaceuticals and Antibody Drug Conjugates
M. Horner, M. Hinrichs, N. Buss
20162 citations
Semantic Scholar
Modeling the pharmacokinetic‐pharmacodynamic relationship of the monoclonal anti‐macaque‐IL‐15 antibody Hu714MuXHu in cynomolgus monkeys
Wei-Jian Pan, Hong Li, Jim J. Xiao, M. Horner +12 more
2015Pharmacology Research & Perspectives2 citations Open access
Semantic Scholar
DependentHomeostasis of Human NK Cells Is Not IL-15
K. Narayanan, Eric A. Butz, Nian-Yu Li, M. Retter +11 more
20130 citations
Semantic Scholar
Toxicity and Pharmacodynamics of Cy317HuXCy, A Surrogate for AMG 317, in Cynomolgus Monkeys: 4-week and 13-Week Repeated-Dose Studies
M. Horner, L. Carlock, R. Caldwell, A. Mould +2 more
20080 citations Open access
Semantic Scholar
Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine deficient child leukemia me th yltra n sfe ra se- with acute lymphocytic
W. Evans, M. Horner, Ya-Qin Chu, D. Kalwinsky +1 more
19910 citations
Semantic Scholar

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