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K. L. Brown · SciRah

Researcher profile · Semantic Scholar

K. L. Brown

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K. L. Brown — researcher profile on SciRah

h-index: 36
Works: 96
Citations: 5,296

Most-cited papers

Cationic host defense (antimicrobial) peptides.
K. L. Brown, R. Hancock
2006Current Opinion in Immunology840 citations
Semantic Scholar
Modulation of the TLR-Mediated Inflammatory Response by the Endogenous Human Host Defense Peptide LL-371
N. Mookherjee, K. L. Brown, D. Bowdish, Silvana Doria +10 more
2006Journal of Immunology582 citations Open access
Semantic Scholar
Do US Black Women Experience Stress-Related Accelerated Biological Aging?
A. Geronimus, M. Hicken, J. Pearson, Sarah Seashols +2 more
2010Human Nature387 citations Open access
Semantic Scholar
Host defence peptides from invertebrates--emerging antimicrobial strategies.
R. Hancock, K. L. Brown, N. Mookherjee
2006Immunobiology288 citations
Semantic Scholar
Intracellular generation of superoxide by the phagocyte NADPH oxidase: how, where, and what for?
J. Bylund, K. L. Brown, C. Movitz, C. Dahlgren +1 more
2010Free Radical Biology & Medicine207 citations
Semantic Scholar
Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils.
A. Karlsson, K. Christenson, M. Matlak, Åse Björstad +5 more
2008Glycobiology171 citations Open access
Semantic Scholar
Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses
K. L. Brown, Grace F. T. Poon, Darlene Birkenhead, O. Peña +6 more
2011Journal of Immunology163 citations Open access
Semantic Scholar
The Where, When, How, and Why of Hyaluronan Binding by Immune Cells
Sally S. M. Lee-Sayer, Yifei Dong, A. Arif, Mia Olsson +2 more
2015Frontiers in Immunology160 citations Open access
Semantic Scholar
Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS‐independent activation of NF‐κB
J. Bylund, K. MacDonald, K. L. Brown, P. Mydel +3 more
2007European Journal of Immunology118 citations Open access
Semantic Scholar
Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide
N. Mookherjee, H. L. Wilson, Silvana Doria, Y. Popowych +12 more
2006Journal of Leukocyte Biology117 citations
Semantic Scholar
Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury
Nina Hellström Erkenstam, P. L. P. Smith, B. Fleiss, Syam Nair +8 more
2016Frontiers in Cellular Neuroscience113 citations Open access
Semantic Scholar
A role for the cell adhesion molecule CD44 and sulfation in leukocyte-endothelial cell adhesion during an inflammatory response?
P. Johnson, A. Maiti, K. L. Brown, Ruihong Li
2000Biochemical Pharmacology113 citations
Semantic Scholar
Galectin 3 aggravates joint inflammation and destruction in antigen-induced arthritis.
H. Forsman, U. Islander, E. Andréasson, A. Andersson +6 more
2011Arthritis & Rheumatism108 citations
Semantic Scholar
Transcriptional silencing by the mycobacteriophage L5 repressor
K. L. Brown, G. Sarkis, Curtis Wadsworth, G. Hatfull
1997EMBO Journal105 citations Open access
Semantic Scholar
Complexities of targeting innate immunity to treat infection.
K. L. Brown, C. Cosseau, J. Gardy, R. Hancock
2007Trends in immunology99 citations
Semantic Scholar
Profile of blood cells and inflammatory mediators in periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome
K. L. Brown, P. Wekell, V. Osla, M. Sundqvist +4 more
2010BMC Pediatrics96 citations Open access
Semantic Scholar
Molecular cloning and characterization of two genes encoding sigma factors that direct transcription from a Bacillus thuringiensis crystal protein gene promoter
L. F. Adams, K. L. Brown, H. R. Whiteley
1991Journal of Bacteriology93 citations Open access
Semantic Scholar
Isolation of a Bacillus thuringiensis RNA polymerase capable of transcribing crystal protein genes.
K. L. Brown, H. R. Whiteley
1988Proceedings of the National Academy of Sciences of the United States of America93 citations Open access
Semantic Scholar
Isolation and characterization of the major vegetative RNA polymerase of Streptomyces coelicolor A3(2); renaturation of a sigma subunit using GroEL
K. L. Brown, S. Wood, M. Buttner
1992Molecular Microbiology91 citations
Semantic Scholar
Novel anti-infectives: is host defence the answer?
P. Hamill, K. L. Brown, H. Jenssen, R. Hancock
2008Current Opinion in Biotechnology90 citations
Semantic Scholar
Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-α, interleukin-12 or upregulate co-stimulatory molecules in dendritic cells or macrophages
Yifei Dong, A. Arif, Mia Olsson, Valbona Cali +7 more
2016Scientific Reports88 citations Open access
Semantic Scholar
ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease.
K. L. Brown, J. Bylund, K. MacDonald, G. Song-Zhao +4 more
2008Clinical Immunology81 citations
Semantic Scholar
Innate defense regulator peptide 1018 protects against perinatal brain injury
Hayde Bolouri, K. Sävman, Wei Wang, A. Thomas +8 more
2014Annals of Neurology76 citations Open access
Semantic Scholar
Isolation of the second Bacillus thuringiensis RNA polymerase that transcribes from a crystal protein gene promoter
K. L. Brown, H. R. Whiteley
1990Journal of Bacteriology70 citations Open access
Semantic Scholar
Role of Sulfation in CD44-Mediated Hyaluronan Binding Induced by Inflammatory Mediators in Human CD14+ Peripheral Blood Monocytes1
K. L. Brown, A. Maiti, Pauline Johnson
2001Journal of Immunology67 citations Open access
Semantic Scholar
Differential Use of Chondroitin Sulfate to Regulate Hyaluronan Binding by Receptor CD44 in Inflammatory and Interleukin 4-activated Macrophages*
B. Ruffell, Grace F. T. Poon, Sally S. M. Lee, K. L. Brown +3 more
2011Journal of Biological Chemistry62 citations Open access
Semantic Scholar
The Host Defense Peptide LL-37 Selectively Permeabilizes Apoptotic Leukocytes
Åse Björstad, Galia Askarieh, K. L. Brown, K. Christenson +9 more
2008Antimicrobial Agents and Chemotherapy59 citations Open access
Semantic Scholar
The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus.
R. Ragotte, Anita Dhanrajani, J. Pleydell-Pearce, K. D. Del Bel +17 more
2017Clinical Immunology58 citations Open access
Semantic Scholar
Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome.
M. Sundqvist, P. Wekell, V. Osla, J. Bylund +8 more
2013Arthritis & Rheumatism50 citations
Semantic Scholar
IRAK-4 mutation (Q293X): rapid detection, and characterisation of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells
D. Davidson, A. Currie, D. Bowdish, K. L. Brown +11 more
2006Journal of Immunology49 citations Open access
Semantic Scholar
Identification of Novel Adenosine Deaminase 2 Gene Variants and Varied Clinical Phenotype in Pediatric Vasculitis
Kristen M Gibson, K. Morishita, P. Dancey, P. Moorehead +14 more
2019Arthritis & Rheumatology48 citations
Semantic Scholar
Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes
M. Sundqvist, K. Christenson, H. Björnsdóttir, V. Osla +6 more
2017Frontiers in Immunology46 citations Open access
Semantic Scholar
Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.
K. L. Brown, Darlene Birkenhead, Jacqueline C Y Lai, Liheng Li +2 more
2005Experimental Cell Research46 citations
Semantic Scholar
Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome
C. Amid, Linda M Rehaume, K. L. Brown, James G. R. Gilbert +3 more
2009BMC Genomics41 citations Open access
Semantic Scholar
Two promoters for the whiB sporulation gene of Streptomyces coelicolor A3(2) and their activities in relation to development
Juan Soliveri, K. L. Brown, M. Buttner, K. Chater
1992Journal of Bacteriology38 citations Open access
Semantic Scholar
Phagocyte-derived reactive oxygen species as suppressors of inflammatory disease.
L. Björkman, C. Dahlgren, A. Karlsson, K. L. Brown +1 more
2008Arthritis & Rheumatism37 citations
Semantic Scholar
Latent gammaherpesvirus exacerbates arthritis through modification of age-associated B cells
Isobel C. Mouat, Zachary J Morse, I. Shanina, K. L. Brown +1 more
2021eLife28 citations Open access
Semantic Scholar
Divergent Effects on Phagocytosis by Macrophage-Derived Oxygen Radicals
K. L. Brown, K. Christenson, A. Karlsson, C. Dahlgren +1 more
2009Journal of Innate Immunity25 citations
Semantic Scholar
Clinical practice variation and need for pediatric-specific treatment guidelines among rheumatologists caring for children with ANCA-associated vasculitis: an international clinician survey
C. Westwell-Roper, J. Lubieniecka, K. L. Brown, K. Morishita +9 more
2017Pediatric Rheumatology Online Journal24 citations Open access
Semantic Scholar
Expression of N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs)-1 and -4 in human monocytes: GlcNAc6ST-1 is implicated in the generation of the 6-sulfo N-acetyllactosamine/Lewis x epitope on CD44 and is induced by TNF-alpha.
S. Tjew, K. L. Brown, R. Kannagi, Pauline Johnson
2005Glycobiology23 citations
Semantic Scholar
Methods for type I interferon detection and their relevance for clinical utility and improved understanding of rheumatic diseases.
L. Lamot, I. Niemietz, K. L. Brown
2019Clinical and Experimental Rheumatology21 citations
Semantic Scholar
Hyaluronan promotes intracellular ROS production and apoptosis in TNFα-stimulated neutrophils
I. Niemietz, K. L. Brown
2023Frontiers in Immunology16 citations Open access
Semantic Scholar
S100A12 Serum Levels and PMN Counts Are Elevated in Childhood Systemic Vasculitides Especially Involving Proteinase 3 Specific Anti-neutrophil Cytoplasmic Antibodies
K. L. Brown, J. Lubieniecka, G. Armaroli, K. Kessel +10 more
2018Frontiers in Pediatrics16 citations Open access
Semantic Scholar
dcDegenerate Oligonucleotide Primed-PCR for Multilocus, Genome-wide Analysis From Limited Quantities of DNA
Michelle D. Bonnette, Victoria R. Pavlova, Denise N. Rodier, L. Thompson +6 more
2009Diagnostic molecular pathology (Print)15 citations
Semantic Scholar
CLINICAL NEUROSCIENCE AND NEUROPATHOLOGY: Fetal cell grafts provide long-term protection against scrapie induced neuronal loss
K. L. Brown, J. Brown, D. Ritchie, J. R. Fraser
15 citations
Semantic Scholar
G-protein-coupled receptor independent, immunomodulatory properties of chemokine CXCL9.
Jiang-Hong Gong, Erin F. Nicholls, M. Elliott, K. L. Brown +7 more
2010Cellular Immunology14 citations
Semantic Scholar
Assaying Phage-Borne Peptides by Phage Capture on Fibrinogen or Streptavidin
L. Bonnycastle, K. L. Brown, Jonathan C. Y. Tang, J. K. Scott
1997Biological chemistry13 citations
Semantic Scholar
Hyaluronan primes the oxidative burst in human neutrophils
I. Niemietz, Abigail T Moraes, M. Sundqvist, K. L. Brown
2020Journal of Leukocyte Biology12 citations
Semantic Scholar
Adenosine deaminase 2 activity negatively correlates with age during childhood
S. M. Bowers, Kristen M Gibson, D. Cabral, K. L. Brown
2020Pediatric Rheumatology Online Journal12 citations Open access
Semantic Scholar
Different Disease Endotypes in Phenotypically Similar Vasculitides Affecting Small-to-Medium Sized Blood Vessels
Erin E. Gill, Maren L. Smith, Kristen M Gibson, K. Morishita +10 more
2021Frontiers in Immunology11 citations Open access
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