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P. Worsham · SciRah

Researcher profile · Semantic Scholar

P. Worsham

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P. Worsham — researcher profile on SciRah

h-index: 29
Works: 74
Citations: 3,815

Most-cited papers

Microevolution and history of the plague bacillus, Yersinia pestis.
M. Achtman, G. Morelli, P. Zhu, T. Wirth +13 more
2004Proceedings of the National Academy of Sciences of the United States of America498 citations Open access
Semantic Scholar
Postexposure prophylaxis against experimental inhalation anthrax.
A. Friedlander, S. Welkos, M. L. M. Pitt, J. Ezzell +7 more
1993Journal of Infectious Diseases410 citations
Semantic Scholar
Identification and Characterization of Variable-Number Tandem Repeats in the Yersinia pestis Genome
A. Klevytska, Lance B. Price, J. Schupp, P. Worsham +2 more
2001Journal of Clinical Microbiology233 citations Open access
Semantic Scholar
Quantitative plating of Histoplasma capsulatum without addition of conditioned medium or siderophores.
P. Worsham, William E. Goldman
1988Journal of Medical and Veterinary Mycology183 citations
Semantic Scholar
Bacillus anthracis comparative genome analysis in support of the Amerithrax investigation
D. Rasko, P. Worsham, T. Abshire, Scott Stanley +14 more
2011Proceedings of the National Academy of Sciences of the United States of America175 citations Open access
Semantic Scholar
Pathology of experimental pneumonic plague produced by fraction 1-positive and fraction 1-negative Yersinia pestis in African green monkeys (Cercopithecus aethiops).
K. Davis, David L. Fritz, M. L. Pitt, S. Welkos +2 more
1996Archives of Pathology & Laboratory Medicine160 citations
Semantic Scholar
Complete Genome Sequence of Yersinia pestis Strains Antiqua and Nepal516: Evidence of Gene Reduction in an Emerging Pathogen
P. Chain, Ping Hu, S. Malfatti, L. Radnedge +5 more
2006Journal of Bacteriology158 citations Open access
Semantic Scholar
Relationship between virulence and immunity as revealed in recent studies of the F1 capsule of Yersinia pestis.
Arthur M. Friedlander, S. Welkos, P. Worsham, Gerard P. Andrews +5 more
1995Clinical Infectious Diseases154 citations
Semantic Scholar
Diversity in a Variable-Number Tandem Repeat fromYersinia pestis
D. M. Adair, P. Worsham, K. Hill, A. Klevytska +3 more
2000Journal of Clinical Microbiology146 citations Open access
Semantic Scholar
Genome Sequence of the Deep-Rooted Yersinia pestis Strain Angola Reveals New Insights into the Evolution and Pangenome of the Plague Bacterium
M. Eppinger, P. Worsham, M. Nikolich, David R. Riley +5 more
2010Journal of Bacteriology110 citations Open access
Semantic Scholar
Genetic Variability of Yersinia pestis Isolates as Predicted by PCR-Based IS100 Genotyping and Analysis of Structural Genes Encoding Glycerol-3-Phosphate Dehydrogenase (glpD)
V. Motin, Anca M. Georgescu, J. Elliott, Ping Hu +7 more
2002Journal of Bacteriology107 citations Open access
Semantic Scholar
Protection of mice from fatal bubonic and pneumonic plague by passive immunization with monoclonal antibodies against the F1 protein of Yersinia pestis.
George W. Anderson, P. Worsham, C. Bolt, G. P. Andrews +3 more
1997American Journal of Tropical Medicine and Hygiene103 citations
Semantic Scholar
Design and Testing for a Nontagged F1‐V Fusion Protein as Vaccine Antigen against Bubonic and Pneumonic Plague
B. Powell, Gerard P. Andrews, Jeffrey T. Enama, S. Jendrek +8 more
2005Biotechnology progress (Print)94 citations
Semantic Scholar
Studies on the contribution of the F1 capsule-associated plasmid pFra to the virulence of Yersinia pestis.
S. Welkos, K. Davis, L. Pitt, P. Worsham +1 more
1995Contributions to microbiology and immunology93 citations
Semantic Scholar
The Complete Genome Sequence of Bacillus anthracis Ames “Ancestor”
J. Ravel, Ling-Xia Jiang, Scott Stanley, Mark R. Wilson +7 more
2008Journal of Bacteriology91 citations Open access
Semantic Scholar
Genome plasticity in Yersinia pestis.
L. Radnedge, P. G. Agron, P. Worsham, G. Andersen
2002Microbiology89 citations Open access
Semantic Scholar
Efficacy of a standard human anthrax vaccine against Bacillus anthracis aerosol spore challenge in rhesus monkeys
B. Ivins, P. Fellows, M. Pitt, J. Estep +3 more
199683 citations
Semantic Scholar
Identification of Nucleotide Sequences for the Specific and Rapid Detection of Yersinia pestis
L. Radnedge, Silvia Gamez-Chin, P. McCready, P. Worsham +1 more
2001Applied and Environmental Microbiology60 citations Open access
Semantic Scholar
Characterization of Burkholderia pseudomallei Strains Using a Murine Intraperitoneal Infection Model and In Vitro Macrophage Assays
S. Welkos, C. Klimko, S. Kern, J. Bearss +7 more
2015PLoS ONE55 citations Open access
Semantic Scholar
Killer toxin production in Pichia acaciae is associated with linear DNA plasmids
P. Worsham, P. L. Bolen
1990Current Genetics54 citations
Semantic Scholar
Journal of Immune Based Therapies and Vaccines an Alternative Approach to Combination Vaccines: Intradermal Administration of Isolated Components for Control of Anthrax, Botulism, Plague and Staphylococcal Toxic Shock
Garry L. Morefield, R. Tammariello, B. Purcell, P. Worsham +18 more
51 citations
Semantic Scholar
The role of the phoPQ operon in the pathogenesis of the fully virulent CO92 strain of Yersinia pestis and the IP32953 strain of Yersinia pseudotuberculosis.
J. Bozue, S. Mou, Krishna L. Moody, C. Cote +3 more
2011Microbial Pathogenesis47 citations
Semantic Scholar
Construction of defined F1 negative mutants of virulent Yersinia pestis.
P. Worsham, M. Stein, S. Welkos
1995Contributions to microbiology and immunology46 citations
Semantic Scholar
Human Anti-Plague Monoclonal Antibodies Protect Mice from Yersinia pestis in a Bubonic Plague Model
Xiao-Dong Xiao, Zhong-Yu Zhu, Jennifer L. Dankmeyer, Michael M Wormald +5 more
2010PLoS ONE40 citations Open access
Semantic Scholar
Pestoides F, an atypical Yersinia pestis strain from the former Soviet Union.
Emilio García, P. Worsham, S. Bearden, S. Malfatti +4 more
2007Advances in Experimental Medicine and Biology39 citations Open access
Semantic Scholar
CpG oligodeoxynucleotides augment the murine immune response to the Yersinia pestis F1-V vaccine in bubonic and pneumonic models of plague.
K. Amemiya, J. Meyers, Taralyn E Rogers, R. Fast +6 more
2009Vaccine36 citations
Semantic Scholar
Characterization of pathogenesis of and immune response to Burkholderia pseudomallei K96243 using both inhalational and intraperitoneal infection models in BALB/c and C57BL/6 mice
J. Bearss, M. Hunter, Jennifer L. Dankmeyer, K. A. Fritts +12 more
2017PLoS ONE35 citations Open access
Semantic Scholar
Activation of Toll-Like Receptors by Live Gram-Negative Bacterial Pathogens Reveals Mitigation of TLR4 Responses and Activation of TLR5 by Flagella
K. Amemiya, Jennifer L. Dankmeyer, R. C. Bernhards, David P. Fetterer +3 more
2021Frontiers in Cellular and Infection Microbiology32 citations Open access
Semantic Scholar
Pestoides F, a Yersinia pestis strain lacking plasminogen activator, is virulent by the aerosol route.
P. Worsham, C. Roy
2003Advances in Experimental Medicine and Biology30 citations
Semantic Scholar
Protection Elicited by Attenuated Live Yersinia pestis Vaccine Strains against Lethal Infection with Virulent Y. pestis
C. Cote, Sergei S. Biryukov, C. Klimko, J. Shoe +10 more
2021Vaccines29 citations Open access
Semantic Scholar
In Vitro Antibiotic Susceptibilities of Yersinia pestis Determined by Broth Microdilution following CLSI Methods
H. Heine, Jeremy R. Hershfield, C. Marchand, L. Miller +3 more
2015Antimicrobial Agents and Chemotherapy28 citations Open access
Semantic Scholar
Development of a genetic transformation system for Histoplasma capsulatum: Complementation of uracil auxotrophy
P. Worsham, W. Goldman
1990Molecular and General Genetics MGG26 citations
Semantic Scholar
Novel Plasmids and Resistance Phenotypes in Yersinia pestis: Unique Plasmid Inventory of Strain Java 9 Mediates High Levels of Arsenic Resistance
M. Eppinger, L. Radnedge, G. Andersen, N. Vietri +4 more
2012PLoS ONE25 citations Open access
Semantic Scholar
Disease progression in mice exposed to low-doses of aerosolized clinical isolates of Burkholderia pseudomallei
S. R. Trevino, C. Klimko, M. Reed, Michael J Aponte-Cuadrado +21 more
2018PLoS ONE24 citations Open access
Semantic Scholar
Comparison of the early host immune response to two widely diverse virulent strains of Burkholderia pseudomallei that cause acute or chronic infections in BALB/c mice.
K. Amemiya, Jennifer L. Dankmeyer, David P. Fetterer, P. Worsham +2 more
2015Microbial Pathogenesis21 citations
Semantic Scholar
Interrogation of the Burkholderia pseudomallei Genome to Address Differential Virulence among Isolates
J. Challacombe, Chris J. Stubben, C. Klimko, S. Welkos +5 more
2014PLoS ONE21 citations Open access
Semantic Scholar
Selection and characterization of ura5 mutants of Histoplasma capsulatum
P. Worsham, W. Goldman
1988Molecular and General Genetics MGG20 citations
Semantic Scholar
Deletion of Two Genes in Burkholderia pseudomallei MSHR668 That Target Essential Amino Acids Protect Acutely Infected BALB/c Mice and Promote Long Term Survival
K. Amemiya, Jennifer L. Dankmeyer, Sergei S. Biryukov, S. R. Trevino +7 more
2019Vaccines19 citations Open access
Semantic Scholar
Assays for the rapid and specific identification of North American Yersinia pestis and the common laboratory strain CO92.
A. Vogler, E. Driebe, Judy Lee, Raymond K. Auerbach +8 more
2008BioTechniques19 citations Open access
Semantic Scholar
Impact of Toll-Like Receptor-Specific Agonists on the Host Immune Response to the Yersinia pestis Plague rF1V Vaccine
Sergei S. Biryukov, Jennifer L. Dankmeyer, Z. Shamsuddin, I. Velez +12 more
2021Frontiers in Immunology17 citations Open access
Semantic Scholar
The D-alanyl-d-alanine carboxypeptidase enzyme is essential for virulence in the Schu S4 strain of Francisella tularensis and a dacD mutant is able to provide protection against a pneumonic challenge.
T. Kijek, S. Mou, B. Bachert, Kathleen A. Kuehl +4 more
2019Microbial Pathogenesis16 citations Open access
Semantic Scholar
A Yersinia pestis tat Mutant Is Attenuated in Bubonic and Small-Aerosol Pneumonic Challenge Models of Infection but Not As Attenuated by Intranasal Challenge
J. Bozue, C. Cote, Taylor B. Chance, J. Kugelman +9 more
2014PLoS ONE16 citations Open access
Semantic Scholar
A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia
Taylor B. Chance, Jennifer Chua, R. Toothman, J. Ladner +15 more
2017PLoS ONE15 citations Open access
Semantic Scholar
Francisella tularensis type B ΔdsbA mutant protects against type A strain and induces strong inflammatory cytokine and Th1-like antibody response in vivo.
A. Strašková, P. Spidlova, S. Mou, P. Worsham +3 more
2015Pathogens and Disease14 citations Open access
Semantic Scholar
Two stable variants of Burkholderia pseudomallei strain MSHR5848 express broadly divergent in vitro phenotypes associated with their virulence differences
A. Shea, R. C. Bernhards, C. Cote, C. J. Chase +14 more
2017PLoS ONE12 citations Open access
Semantic Scholar
Comparative virulence of three different strains of Burkholderia pseudomallei in an aerosol non-human primate model
S. R. Trevino, Jennifer L. Dankmeyer, David P. Fetterer, C. Klimko +9 more
2021PLoS Neglected Tropical Diseases10 citations Open access
Semantic Scholar
Dysregulation of TNF-α and IFN-γ expression is a common host immune response in a chronically infected mouse model of melioidosis when comparing multiple human strains of Burkholderia pseudomallei
K. Amemiya, Jennifer L. Dankmeyer, J. Bearss, Xian-Kun Zeng +9 more
2020BMC Immunology10 citations Open access
Semantic Scholar
A strategy to verify the absence of the pgm locus in Yersinia pestis strain candidates for select agent exemption.
A. Jenkins, P. Worsham, S. Welkos
2009Journal of Microbiological Methods10 citations
Semantic Scholar
The Impact of Age and Sex on Mouse Models of Melioidosis
C. Klimko, S. R. Trevino, Alicia M. Moreau, Michael J. Aponte Cuadrado +7 more
2020Pathogens9 citations Open access
Semantic Scholar
Comparison of three non-human primate aerosol models for glanders, caused by Burkholderia mallei.
D. Waag, Taylor B. Chance, S. R. Trevino, Franco D. Rossi +10 more
2021Microbial Pathogenesis6 citations Open access
Semantic Scholar

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