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G. Aversa · SciRah

Researcher profile · Semantic Scholar

G. Aversa

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G. Aversa — researcher profile on SciRah

h-index: 37
Works: 90
Citations: 7,444

Most-cited papers

Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.
J. Punnonen, G. Aversa, B. G. Cocks, A. N. McKenzie +4 more
1993Proceedings of the National Academy of Sciences of the United States of America1,156 citations Open access
Semantic Scholar
The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
J. Sayós, Cheng-Bin Wu, M. Morra, Ning-Hai Wang +10 more
1998Nature992 citations
Semantic Scholar
Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.
A. N. McKenzie, J. Culpepper, R. de Waal Malefyt, F. Briére +6 more
1993Proceedings of the National Academy of Sciences of the United States of America585 citations Open access
Semantic Scholar
A novel receptor involved in T-cell activation
B. Cocks, C.-C. Chang, J. Carballido, H. Yssel +2 more
1995Nature530 citations
Semantic Scholar
Identification of Functional Human Splenic Memory B Cells by Expression of CD148 and CD27
S. Tangye, Yong-Jun Liu, G. Aversa, J. Phillips +1 more
1998Journal of Experimental Medicine512 citations Open access
Semantic Scholar
Anti-CD40 monoclonal antibodies or CD4+ T cell clones and IL-4 induce IgG4 and IgE switching in purified human B cells via different signaling pathways.
H. Gascan, J. Gauchat, G. Aversa, P. van Vlasselaer +1 more
1991Journal of Immunology281 citations
Semantic Scholar
IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand.
B. G. Cocks, R. de Waal Malefyt, J. Galizzi, J. D. de Vries +1 more
1993International Immunology265 citations
Semantic Scholar
An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13- induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors
G. Aversa, J. Punnonen, B. G. Cocks, R. de Waal Malefyt +4 more
1993Journal of Experimental Medicine234 citations Open access
Semantic Scholar
Soluble and Membrane-bound Forms of Signaling Lymphocytic Activation Molecule (SLAM) Induce Proliferation and Ig Synthesis by Activated Human B Lymphocytes
J. Punnonen, B. Cocks, J. Carballido, B. Bennett +3 more
1997Journal of Experimental Medicine193 citations Open access
Semantic Scholar
Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production.
G. Aversa, Chia-Chun J. Chang, J. Carballido, B. Cocks +1 more
1997Journal of Immunology179 citations Open access
Semantic Scholar
The 26-kD transmembrane form of tumor necrosis factor alpha on activated CD4+ T cell clones provides a costimulatory signal for human B cell activation
G. Aversa, J. Punnonen, J. D. de Vries
1993Journal of Experimental Medicine172 citations Open access
Semantic Scholar
INDUCTION OF LONG‐TERM SPECIFIC TOLERANCE TO ALLOGRAFTS IN RATS BY THERAPY WITH AN ANTI‐CD3-LIKE MONOCLONAL ANTIBODY
M. Nicolls, G. Aversa, N. W. Pearce, Austin Spinelli +3 more
1993Transplantation155 citations Open access
Semantic Scholar
Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Th1 and Th2 cells.
António G. Castro, Thomas Hauser, B. G. Cocks, J. Abrams +10 more
1999Journal of Immunology152 citations Open access
Semantic Scholar
IL-10 alters DC function via modulation of cell surface molecules resulting in impaired T-cell responses.
J. McBride, T. Jung, J. D. de Vries, G. Aversa
2002Cellular Immunology137 citations
Semantic Scholar
Modulation of IL-4 induced germline ε RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE production
J. Gauchat, G. Aversa, H. Gascan, J. D. de Vries
1992110 citations
Semantic Scholar
SLAM and its role in T cell activation and Th cell responses
G. Aversa, J. Carballido, J. Punnonen, Chia-Chun J. Chang +3 more
1997Immunology and Cell Biology106 citations
Semantic Scholar
Regulation of IgE synthesis by cytokines.
J. D. de Vries, J. Gauchat, G. Aversa, J. Punnonen +2 more
1991Current Opinion in Immunology101 citations
Semantic Scholar
Reversal of human allergic T helper 2 responses by engagement of signaling lymphocytic activation molecule.
J. Carballido, G. Aversa, K. Kaltoft, B. Cocks +4 more
1997Journal of Immunology95 citations Open access
Semantic Scholar
Receptors and cytokines involved in allergic TH2 cell responses.
J. D. de Vries, J. Carballido, G. Aversa
1999Journal of Allergy and Clinical Immunology90 citations
Semantic Scholar
Regulation of the human IgE response by IL4 and IL13.
J. D. de Vries, J. Punnonen, B. Cocks, R. de Waal Malefyt +1 more
1993Research in Immunology81 citations
Semantic Scholar
Cytokine production and surface marker expression in acute and stable multiple sclerosis: altered IL-12 production and augmented signaling lymphocytic activation molecule (SLAM)-expressing lymphocytes in acute multiple sclerosis.
P. Ferrante, M. Fusi, M. Saresella, D. Caputo +8 more
1998Journal of Immunology79 citations Open access
Semantic Scholar
Gene transfer with IL‐4 and IL‐13 improves survival in lethal endotoxemia in the mouse and ameliorates peritoneal macrophages immune competence
Julie M. Baumhofer, B. Beinhauer, Jacob E. Wang, H. Brandmeier +5 more
1998European Journal of Immunology78 citations Open access
Semantic Scholar
Systematic identification of regulatory proteins critical for T-cell activation
P. Chu, Jorge Pardo, Hao-Ran Zhao, Connie Li +13 more
2003Journal of Biology77 citations Open access
Semantic Scholar
Role of interleukin‐4 and interleukin‐13 in synthesis of IgE and expression of CD23 by human B cells
J. Punnonen, G. Aversa, B. G. Cocks, J. E. Vries
1994Allergy. European Journal of Allergy and Clinical Immunology76 citations
Semantic Scholar
Interleukin 10 regulates cell surface and soluble LIR‐2 (CD85d) expression on dendritic cells resulting in T cell hyporesponsiveness in vitro
B. Beinhauer, J. McBride, Philipp Graf, E. Pursch +6 more
2004European Journal of Immunology71 citations
Semantic Scholar
Increased expression of signaling lymphocytic activation molecule in patients with rheumatoid arthritis and its role in the regulation of cytokine production in rheumatoid synovium.
P. Isomäki, G. Aversa, B. Cocks, R. Luukkainen +4 more
1997Journal of Immunology71 citations Open access
Semantic Scholar
Functional Cloning of Src-like Adapter Protein-2 (SLAP-2), a Novel Inhibitor of Antigen Receptor Signaling
S. Holland, X. Liao, M. Mendenhall, Xiu-Lan Zhou +22 more
2001Journal of Experimental Medicine68 citations Open access
Semantic Scholar
Induction of isotype switching and Ig production by CD5+ and CD10+ human fetal B cells.
J. Punnonen, G. Aversa, B. Vandekerckhove, M. Roncarolo +1 more
1992Journal of Immunology68 citations
Semantic Scholar
Signaling lymphocytic activation molecule (SLAM) regulates T cellular cytotoxicity
Golo Henning, Michael S. Kraft, T. Derfuss, R. Pirzer +4 more
2001European Journal of Immunology55 citations Open access
Semantic Scholar
Peptide-induced anergy in allergen-specific human Th2 cells results in lack of cytokine production and B cell help for IgE synthesis. Reversal by IL-2, not by IL-4 or IL-13.
Stephan Fasler, G. Aversa, A. Terr, Kristian Thestrup-Pedersen +2 more
1995Journal of Immunology50 citations Open access
Semantic Scholar
Lymphocyte adhesion molecules in T cell-mediated lysis of human kidney cells.
M. Suranyi, G. Bishop, C. Clayberger, A. Krensky +3 more
1991Kidney International50 citations Open access
Semantic Scholar
CD148: a receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation.
S. Tangye, Joseph H. Phillips, L. Lanier, J. D. de Vries +1 more
1998Journal of Immunology47 citations
Semantic Scholar
Membranes of activated CD4+ T cells expressing T cell receptor (TcR) αβ or TcR γδ induce IgE synthesis by human B cells in the presence of interleukin‐4
H. Gascan, G. Aversa, J. Gauchat, P. van Vlasselaer +5 more
199243 citations
Semantic Scholar
A Novel Role for p21-Activated Protein Kinase 2 in T Cell Activation
P. Chu, Jun Wu, X. Liao, Jorge Pardo +11 more
2004Journal of Immunology42 citations
Semantic Scholar
CD40 ligand-CD40 interaction in Ig isotype switching in mature and immature human B cells.
G. Aversa, Juha Punnonen, J. Carballido, B. G. Cocks +1 more
1994Seminars in Immunology42 citations
Semantic Scholar
Negative regulation of human T cell activation by the receptor-type protein tyrosine phosphatase CD148.
S. Tangye, Jun Wu, G. Aversa, J. D. de Vries +2 more
1998Journal of Immunology41 citations
Semantic Scholar
Human pre-B cells differentiate into Ig-secreting plasma cells in the presence of interleukin-4 and activated CD4+ T cells or their membranes
J. Punnonen, G. Aversa, JE de Vries
199337 citations Open access
Semantic Scholar
Signaling Lymphocytic Activation Molecule Expression and Regulation in Human Intracellular Infection Correlate with Th1 Cytokine Patterns1
V. García, María Florencia Quiroga, Maria Teresa Ochoa, L. Ochoa +8 more
2001Journal of Immunology34 citations Open access
Semantic Scholar
The role of T/B cell interactions and cytokines in the regulation of human IgE synthesis.
J. D. de Vries, Juha Punnonen, B. G. Cocks, G. Aversa
1993Seminars in Immunology26 citations
Semantic Scholar
Putting Translational Science onto a Global Stage
C. Gilliland, D. Zuk, P. Kočiš, Mike Johnson +6 more
2016Nature reviews. Drug discovery25 citations Open access
Semantic Scholar
Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumor necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production.
J. Gauchat, G. Aversa, H. Gascan, J. D. de Vries
1992International Immunology25 citations
Semantic Scholar
Brequinar Sodium, Mycophenolic Acid, and Cyclosporin A Inhibit Different Stages of IL‐4‐ or IL‐13‐Induced Human IgG4 and IgE Production In Vitro
Chia-Chun J. Chang, G. Aversa, J. Punnonen, H. Yssel +1 more
1993Annals of the New York Academy of Sciences23 citations
Semantic Scholar
A monoclonal antibody (A6) recognizing a unique epitope restricted to CD45RO and RB isoforms of the leukocyte common antigen family identifies functional T cell subsets.
G. Aversa, J. Waugh, B. Hall
1994Cellular Immunology21 citations
Semantic Scholar
Expression of soluble human signaling lymphocytic activation molecule in vivo.
P. Isomäki, G. Aversa, Chia-Chun J. Chang, Reijo Luukkainen +4 more
1999Journal of Allergy and Clinical Immunology18 citations
Semantic Scholar
Antagonistic peptides specifically inhibit proliferation, cytokine production, CD40L expression, and help for IgE synthesis by Der p 1-specific human T-cell clones.
Stephan Fasler, G. Aversa, J. D. de Vries, H. Yssel
1998Journal of Allergy and Clinical Immunology17 citations Open access
Semantic Scholar
Detection of a late lymphocyte activation marker by A1, a new monoclonal antibody.
G. Aversa, M. Suranyi, J. Waugh, A. Bishop +1 more
1988Transplantation Proceedings17 citations
Semantic Scholar
Inhibition of human IgE synthesis in vitro and in SCID-hu mice by an interleukin-4 receptor antagonist.
J. Carballido, G. Aversa, D. Schols, J. Punnonen +1 more
1995International Archives of Allergy and Immunology16 citations
Semantic Scholar
Human pre-B cells differentiate into Ig-secreting plasma cells in the presence of interleukin-4 and activated CD4+ T cells or their membranes.
J. Punnonen, G. Aversa, JE de Vries
1993Blood16 citations Open access
Semantic Scholar
Membranes of activated CD4+ T cells expressing T cell receptor (TcR) alpha beta or TcR gamma delta induce IgE synthesis by human B cells in the presence of interleukin-4.
H. Gascan, G. Aversa, J. Gauchat, P. van Vlasselaer +5 more
1992European Journal of Immunology13 citations
Semantic Scholar
Altered signaling lymphocytic activation molecule (SLAM) expression in HIV infection and redirection of HIV-specific responses via SLAM triggering.
Luca Meroni, M. Fusi, S. Varchetta, Mara Biasin +6 more
1999Clinical Immunology12 citations
Semantic Scholar

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J. D. de Vries×28
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J. D. de Vries — researcher profile on SciRah
J. Punnonen×16
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J. Punnonen — researcher profile on SciRah
B. G. Cocks×9
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B. G. Cocks — researcher profile on SciRah
J. Carballido×8
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J. Carballido — researcher profile on SciRah

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H. Yssel — researcher profile on SciRah

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B. Cocks — researcher profile on SciRah

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H. Gascan — researcher profile on SciRah

R. de Waal Malefyt×5

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R. de Waal Malefyt — researcher profile on SciRah

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J. Gauchat — researcher profile on SciRah

M. Roncarolo×4

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M. Roncarolo — researcher profile on SciRah

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S. Tangye — researcher profile on SciRah

Chia-Chun J. Chang×4

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Chia-Chun J. Chang — researcher profile on SciRah