D. D. Flynn

Most-cited papers

1. Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation.

   D. Mash, D. D. Flynn, L. Potter

   1985Science711 citations

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2. Cocaethylene: A Unique Cocaine Metabolite Displays High Affinity for the Dopamine Transporter

   W. Hearn, D. D. Flynn, G. Hime, Stefan Rose +4 more

   1991Journal of Neurochemistry289 citations

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3. Characterization of l‐[3H]Nicotine Binding in Human Cerebral Cortex: Comparison Between Alzheimer's Disease and the Normal

   D. D. Flynn, Deborah C. Mash

   1986Journal of Neurochemistry284 citations

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4. Differential Regulation of Molecular Subtypes of Muscarinic Receptors in Alzheimer's Disease

   D. D. Flynn, G. Ferrari-DiLeo, D. Mash, A. Levey

   1995Journal of Neurochemistry239 citations

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5. Loss of high‐affinity agonist binding to M1 muscarinic receptors in Alzheimer's disease: Implications for the failure of cholinergic replacement therapies

   D. D. Flynn, D. A. Weinstein, Deborah C. Mash

   1991Annals of Neurology156 citations

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6. Visualizing Dopamine and Serotonin Transporters in the Human Brain with the Potent Cocaine Analogue [125I]RTI‐55: In Vitro Binding and Autoradiographic Characterization

   Julie K. Staley, M. Basile, D. D. Flynn, Deborah C. Mash

   1994Journal of Neurochemistry125 citations

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7. Characterization and Distribution of Transferrin Receptors in the Rat Brain

   Deborah C. Mash, J. Pablo, D. D. Flynn, S. Efange +1 more

   1990Journal of Neurochemistry102 citations

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8. Distinct kinetic binding propeties of N‐[3H]‐methylscopolamine afford differential labeling and localization of M1, M2, and M3 muscarinic receptor subtypes in primate brain

   D. D. Flynn, D. Mash

   1993Synapse88 citations

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9. Brain-Stimulation Reward Thresholds Raised by an Antisense Oligonucleotide for the M5 Muscarinic Receptor Infused near Dopamine Cells

   J. Yeomans, J. Takeuchi, Marco A. S. Baptista, D. D. Flynn +4 more

   2000Journal of Neuroscience81 citations Open access

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10. The M5 (m5) receptor subtype: fact or fiction?

    Carolyn M. Reever, G. Ferrari-DiLeo, D. D. Flynn

    1997Life Science81 citations Open access

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11. Differential alterations in muscarinic receptor subtypes in Alzheimer's disease: implications for cholinergic-based therapies.

    D. D. Flynn, G. Ferrari-DiLeo, A. Levey, Deborah C. Mash

    1995Life Science76 citations Open access

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12. Multiple in vitro interactions with and differential in vivo regulation of muscarinic receptor subtypes by tetrahydroaminoacridine.

    D. D. Flynn, Deborah C. Mash

    1989Journal of Pharmacology and Experimental Therapeutics68 citations

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13. Attenuation of muscarinic receptor-G-protein interaction in Alzheimer disease.

    G. Ferrari-DiLeo, D. Mash, D. D. Flynn

    1995Molecular and Chemical Neuropathology62 citations

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14. Diminished muscarinic receptor-stimulated [3H]-PIP2 hydrolysis in Alzheimer's disease.

    G. Ferrari-DiLeo, D. D. Flynn

    1993Life Science54 citations Open access

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15. Pharmacological strategies to selectively label and localize muscarinic receptor subtypes

    D. D. Flynn, Carolyn M. Reever, G. Ferrari-DiLeo

    199753 citations

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16. Enzymatic carboxymethylation of the nicotinic acetylcholine receptor.

    Y. Kloog, D. D. Flynn, A. Hoffman, J. Axelrod

    1980Biochemical and Biophysical Research Communications - BBRC45 citations

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17. Selective labeling and localization of the M4 (m4) muscarinic receptor subtype.

    G. Ferrari-DiLeo, M. Waelbroeck, Deborah C. Mash, D. D. Flynn

    1994Molecular Pharmacology41 citations

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18. Interactions of cocaine with primary and secondary recognition sites on muscarinic receptors.

    D. D. Flynn, A. Vaishnav, D. Mash

    1992Molecular Pharmacology41 citations

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19. Pharmacological screen for activities of 12-hydroxyibogamine: a primary metabolite of the indole alkaloid ibogaine

    J. Staley, Qinjie Ouyang, J. Pablo, W. Hearn +4 more

    1996Psychopharmacology37 citations

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20. Different effects of N-ethylmaleimide on M1 and M2 muscarine receptors in rat brain.

    D. D. Flynn, L. Potter

    1985Proceedings of the National Academy of Sciences of the United States of America37 citations Open access

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21. Enzymatic methylation of the membrane-bound nicotinic acetylcholine receptor.

    D. D. Flynn, Y. Kloog, L. Potter, J. Axelrod

    1982Journal of Biological Chemistry33 citations Open access

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22. The interaction of Ca2+/Mg2+ ATPase activator protein and Ca2+ with human erythrocyte membranes.

    D. Hanahan, R. Taverna, D. D. Flynn, Janice E. Ekholm

    1978Biochemical and Biophysical Research Communications - BBRC31 citations

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23. Circadian variations in radioligand binding to muscarine receptors in rat brain dependent upon endogenous agonist occupation.

    D. Mash, D. D. Flynn, L. Kalinoski, L. Potter

    1985Brain Research20 citations

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24. Studies of muscarinic neurotransmission with antimuscarinic toxins.

    L. Potter, D. D. Flynn, Jingsheng Liang, M. McCollum

    2004Progress in Brain Research17 citations

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25. [3H]-(+)-pentazocine binding to sigma recognition sites in human cerebellum.

    C. Zabetian, Julie K. Staley, D. D. Flynn, Deborah C. Mash

    1994Life Science17 citations

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26. Characterization of muscarinic receptors on cultured microglial cells

    G. Ferrari-DiLeo, D. D. Flynn

    199511 citations

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27. Effect of solubilization on the distinct binding properties of muscarine receptors from rabbit hippocampus and brainstem.

    D. D. Flynn, L. Potter

    1986Molecular Pharmacology10 citations

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28. Agonist binding to M1 muscarinic receptors is sensitive to guanine nucleotides.

    D. D. Flynn, Nick Palermo, Alejandro Suarez

    1989European Journal of Pharmacology6 citations

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29. Perinatal cocaine exposure alters sigma binding site density in the placenta

    D. D. Flynn, L. Sanchez-Ramos, D. Mash

    19933 citations

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30. Distinct kinetic binding properties of N-[3H]-methyl-scopolamine afford differential labeling and localization of M1, M2 and M3 muscarinic receptor subtypes

    D. Mash, D. D. Flynn

    19932 citations

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31. LOSS OF HIGH-AFFINITY AGONIST RECEPTOR BINDING IN ALZHEIMER'S DISEASE. AUTHORS' REPLY

    J. De Keyser, D. Mash, D. D. Flynn

    19922 citations

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32. Animmunoprecipitation strategy to examine specific muscarinic receptor-G protein interactions in membranes

    Carolyn M. Reever, G. Ferrari-DiLeo, D. D. Flynn

    19951 citations

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33. Antisense oligonucleotide for the m5 muscarinic receptor in the ventral tegmentum reduces M5 receptor density, but not scopolamine-induced locomotion

    R. P. M. Priebe, A. S. Kumar, D. D. Flynn, J. Fulton +1 more

    19990 citations

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34. Fluorinated Tropinyl Esters for Application with Pet

    A. Emran, J. Lim, D. D. Flynn, M. Emran +2 more

    19950 citations

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35. Abstracts of poster presentationsFurther characterization of the defect in M1 muscarinic receptor-G protein coupling in Alzheimer's disease

    D. D. Flynn, G. Ferrari-DiLeo, J. Carsi, D. Mash

    19930 citations

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36. Reply

    Deborah C. Mash, D. D. Flynn

    19920 citations

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37. Potential application of radiolabeled ligand studies of dementing diseases by positron emission tomography

    D. Mash, D. D. Flynn

    19900 citations

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38. Polyclonal anti-propylbenzilylcholine mustard antibodies selectively recognize labeled muscarinic receptors from rabbit brain.

    P. Strang, D. D. Flynn

    1989Neuroscience Letters0 citations Open access

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39. Different effects of N-ethylmaleimide on Ml and M 2 muscarine receptors in rat brain ( sulihydryl groups / agonist-antagonist affinities / acetylcholine receptor subtypes )

    D. D. Flynn, L. Potter

    0 citations

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