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M. Gohil · SciRah

Researcher profile · Semantic Scholar

M. Gohil

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M. Gohil — researcher profile on SciRah

h-index: 15
Works: 40
Citations: 3,722

Most-cited papers

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
J. Fraietta, S. Lacey, Elena J. Orlando, Iulian Pruteanu-Malinici +33 more
2018Nature Medicine1,598 citations Open access
Semantic Scholar
Disruption of TET2 Promotes the Therapeutic Efficacy of CD19-targeted T-cells
J. Fraietta, Christopher L. Nobles, Morgan A. Sammons, Stefan Lundh +34 more
2018Nature796 citations Open access
Semantic Scholar
PSMA-targeting TGFβ-insensitive Armored CAR T-cells in Metastatic Castration Resistant Prostate Cancer: a Phase 1 Trial
V. Narayan, J. Barber-Rotenberg, In-Young Jung, S. Lacey +36 more
2022Nature Medicine464 citations Open access
Semantic Scholar
Deletion of the inhibitory co-receptor CTLA4 enhances and invigorates chimeric antigen receptor T cells
Sangya Agarwal, M. A. Aznar, Andrew J. Rech, Charly R. Good +16 more
2023Immunity171 citations Open access
Semantic Scholar
The loss of TET2 promotes CD8+ T cell memory differentiation
Shannon A. Carty, M. Gohil, Lauren B. Banks, Renee M. Cotton +6 more
2017Journal of Immunology151 citations Open access
Semantic Scholar
HIF-dependent hematopoietic factors regulate the development of the embryonic vasculature.
D. Ramírez-Bergeron, A. Runge, D. Adelman, M. Gohil +1 more
2006Developmental Cell112 citations Open access
Semantic Scholar
Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis
T. S. Karin Eisinger-Mathason, Vera Mucaj, Kevin Biju, Michael S. Nakazawa +7 more
2015Proceedings of the National Academy of Sciences of the United States of America103 citations Open access
Semantic Scholar
T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool.
Jennifer E. Smith-Garvin, J. Burns, M. Gohil, Tao Zou +5 more
2010Blood79 citations Open access
Semantic Scholar
Akt and mTOR pathways differentially regulate the development of natural and inducible TH17 cells
Jiyeon Kim, Tammarah Sklarz, Lauren B. Banks, M. Gohil +12 more
2013Nature Immunology61 citations Open access
Semantic Scholar
The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability.
B. Krock, T. S. Eisinger-Mathason, Dionysios N. Giannoukos, Jessica E. S. Shay +6 more
2015Blood37 citations Open access
Semantic Scholar
Quadruple adenine base–edited allogeneic CAR T cells outperform CRISPR/Cas9 nuclease–engineered T cells
N. Engel, Israel Steinfeld, Daniel E. Ryan, Kusala Anupindi +14 more
2025Proceedings of the National Academy of Sciences of the United States of America32 citations Open access
Semantic Scholar
Interleukin-18 Secreting Autologous Anti-CD19 CAR T-Cells (huCART19-IL18) in Patients with Non-Hodgkin Lymphomas Relapsed or Refractory to Prior CAR T-Cell Therapy
J. Svoboda, J. Gerson, D. Landsburg, E. Chong +22 more
2022Blood31 citations Open access
Semantic Scholar
mTORC2 regulates multiple aspects of NKT-cell development and function
Tammarah Sklarz, P. Guan, M. Gohil, Renee M. Cotton +4 more
2017European Journal of Immunology25 citations Open access
Semantic Scholar
Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
J. Fraietta, S. Lacey, Elena J. Orlando, Iulian Pruteanu-Malinici +33 more
2021Nature Medicine21 citations Open access
Semantic Scholar
Retraction: Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways
Jiyeon Kim, Tammarah Sklarz, Lauren B. Banks, M. Gohil +12 more
2014Nature Immunology17 citations Open access
Semantic Scholar
The SLP-76 SH2 domain is required for T cell development and activation
J. Burns, Evann Corbo, Janine Degen, M. Gohil +5 more
2011Journal of Immunology13 citations Open access
Semantic Scholar
Characterization of autologous T cells engineered to express NY-ESO-1 TCR with multiplexed CRISPR/Cas9 editing (NYCE T Cells)
Jun Xu, M. Gohil, E. Stadtmauer, J. Fraietta +11 more
20204 citations
Semantic Scholar
Identification of Functional Determinants of Response and Resistance to CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy of Chronic Lymphocytic Leukemia
J. Fraietta, S. Lacey, Elena J. Orlando, Julian Pruteanu +32 more
20174 citations
Semantic Scholar
Abstract 5571: Disruption of cell-intrinsic checkpoint regulator CTLA-4 in CD19 directed CAR T cells provides clinical efficacy in CLL patients
Sangya Agarwal, A. A. Gomez, Tong Da, Shunichiro Kuramitsu +9 more
2022Cancer Research3 citations
Semantic Scholar
In Vivo Persistence and Function of CAR19 T-Cell Products for Pediatric B-Cell Acute Lymphoblastic Leukemia Are Impacted By Media, Cytokine Supplementation and Metabolite Bioavailability during Ex Vivo Manufacturing
Caitlin R. Hopkins, Amanda M. DiNofia, S. Maude, Gregory Chen +21 more
2024Blood2 citations
Semantic Scholar
Myeloid derived suppressor cells (MDSCS) reduce the manufacturing feasibilty of gene modified T cells.
M. Gohil, A. Dai, S. Mackey, D. Negorev +19 more
2019Cytotherapy2 citations
Semantic Scholar
Optimization of CRISPR-Cas9 knock-out of CD33 in human hematopoietic stem / progenitor cells for allogeneic transplantation in patients with acute myeloid leukemia
K. Cummins, January Salas-McKee, I. Kulikovskaya, M. Gohil +4 more
2019Cytotherapy2 citations
Semantic Scholar
TET2 Regulates CD4+ T Follicular Helper Differentiation
M. Gohil, Martha S. Jordan, Shannon A. Carty
20172 citations
Semantic Scholar
Akt2 deficiency impairs Th17 differentiation, augments Th2 differentiation, and alters the peripheral response to immunization
Lauren B Banks, Tammarah Sklarz, M. Gohil, C. O'Leary +5 more
2024bioRxiv1 citations Open access
Semantic Scholar
HARNESSING POTENT NAÏVE LIKE T CELLS FOR PRECISION CAR T MANUFACTURING
A. Jain, K. Amses, M. Markovska, K. M. Haines +16 more
2024Cytotherapy1 citations
Semantic Scholar
Cell-derived Nanoparticles Provide a Robust Platform to Manufacture Therapeutic T cells
Mosha Z. Deng, Tanishk Sinha, Meizan Lai, Shu-Guang Jiang +31 more
2026Research Square0 citations
Semantic Scholar
Process Development and Manufacturing: DEVELOPING AND OPTIMIZING MULTICOLOR FLOW CYTOMETRY METHODS FOR THE MANUFACTURE AND RELEASE OF 3-DAY HUCART PRODUCTS
S. Mackey, A. Dai, N. Gong, B. McGettigan +7 more
2023Cytotherapy0 citations
Semantic Scholar
Process Development and Manufacturing: CAR T CELL MANUFACTURING (MFG) IN A 2ML MICROBIOREACTOR
M. Gohil, A. Jain, K. Lee, E. Pequignot +17 more
2023Cytotherapy0 citations
Semantic Scholar
Process Development and Manufacturing: EVALUATION OF COMMERCIAL CRYOMEDIA FORMULATIONS FOR LEUKAPHERESIS STARTING MATERIAL AND FINAL T CELL THERAPEUTIC PRODUCTS
A. Russell, E. Pequignot, J. Xu, M. Gohil +11 more
2022Cytotherapy0 citations
Semantic Scholar
Comparable stability of cryopreserved leukapheresis and investigational car t-cell clinical products formulated with in-house or commercial cryomedias
K. M. Haines, Jun Xu, E. Pequignot, A. Jain +11 more
20210 citations
Semantic Scholar
Large-scale manufacture of car T cells engineered with augmented proliferative capacity and function via a 3-day process
M. Gohil, J. Xu, J. McKee, J. R. Levine +22 more
20210 citations
Semantic Scholar
Pre-clinical development of multiplex-CRISPR-edited cell and gene therapy products
W. Gladney, E. Hexner, January Salas-McKee, A. Fesnak +11 more
20200 citations
Semantic Scholar
TET2 deficiency promotes CD8+ T cell memory differentiation
Martha S. Jordan, Shannon A. Carty, M. Gohil, Renee M. Cotton +5 more
2017Journal of Immunology0 citations
Semantic Scholar
The Methylcytosine Dioxygenase TET2 Regulates CD8 + T Cell Memory Differentiation
Shannon A. Carty, M. Gohil, Lauren B. Banks, Matthew E. Johnson +5 more
20160 citations Open access
Semantic Scholar
TET2 Regulates CD8+ T Cell Responses to Acute and Chronic Viral Infection
Shannon A. Carty, M. Gohil, Erietta Stelekati, Lauren B. Banks +3 more
20150 citations
Semantic Scholar
Abstract 960: Deregulation of the Hippo pathway in soft tissue sarcoma promotes FOXM1 expression and tumorigenesis
T. S. Karin Eisinger, Vera Mucaj, Kevin Biju, Michael S. Nakazawa +7 more
20150 citations
Semantic Scholar
Integrated Immunological Analysis of the Bone Marrow Tumor Microenvironment in Myeloproliferative Neoplasms to Determine Potential Efficacy of Immune Checkpoint Blockade
R. Orlowski, Alexander C. Huang, M. Gohil, J. Mangan +8 more
20150 citations
Semantic Scholar
TET2 Regulates CD8+ T Cell Differentiation
Shannon A. Carty, M. Gohil, G. Koretzky, Martha S. Jordan
20140 citations
Semantic Scholar
Akt and mTOR pathways differentially regulate the development of natural and inducible T H 17 cells
Jiyeon S. Kim, Tammarah Sklarz, Lauren B. Banks, M. Gohil +12 more
20130 citations
Semantic Scholar
This information is current as Activation Required for T Cell Development and The SLP-76 Src Homology 2 Domain Is
S. Kliche, Martha S. Jordan, C. Anterasian, B. Schraven +5 more
20110 citations
Semantic Scholar

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