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S. Laggai · SciRah

Researcher profile · Semantic Scholar

S. Laggai

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S. Laggai — researcher profile on SciRah

h-index: 13
Works: 24
Citations: 577

Most-cited papers

IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype
SM Kessler, S. Laggai, A. Barghash, CS Schultheiss +5 more
2015Cell Death and Disease85 citations Open access
Semantic Scholar
IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling.
S. Kessler, J. Pokorny, V. Zimmer, S. Laggai +3 more
2013American Journal of Physiology - Gastrointestinal and Liver Physiology66 citations
Semantic Scholar
The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma
Christina S. Schultheiss, S. Laggai, Beate Czepukojc, U. K. Hussein +17 more
2017Cell Stress63 citations Open access
Semantic Scholar
First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy.
C. Dahlem, Ali Abuhaliema, S. Kessler, Tarek Kröhler +11 more
2022ACS Chemical Biology59 citations
Semantic Scholar
Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation
S. Kessler, S. Laggai, E. Van Wonterghem, Katja Gemperlein +6 more
2016Frontiers in Physiology42 citations Open access
Semantic Scholar
Hepatocellular Carcinoma and Nuclear Paraspeckles: Induction in Chemoresistance and Prediction for Poor Survival.
S. Kessler, Kevan Hosseini, U. K. Hussein, Kyoung Min Kim +6 more
2019Cellular Physiology and Biochemistry37 citations Open access
Semantic Scholar
IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer
S. Kessler, E. Lederer, S. Laggai, N. Golob-Schwarzl +16 more
2017OncoTarget36 citations Open access
Semantic Scholar
Hepatic hepcidin expression is decreased in cirrhosis and HCC.
S. Kessler, A. Barghash, S. Laggai, V. Helms +1 more
2015Journal of Hepatology34 citations Open access
Semantic Scholar
Hepatic interleukin-6 production is maintained during endotoxin tolerance and facilitates lipid accumulation.
A. Dembek, S. Laggai, S. Kessler, Beate Czepukojc +3 more
2017Immunobiology33 citations
Semantic Scholar
The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis[S]
S. Laggai, S. Kessler, Stefan Boettcher, Valérie Lebrun +7 more
2014Journal of Lipid Research33 citations Open access
Semantic Scholar
Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH.
S. Laggai, Y. Simon, Theo Ranssweiler, A. Kiemer +1 more
2013World Journal of Hepatology30 citations Open access
Semantic Scholar
The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma
Tarek Kröhler, S. Kessler, Kevan Hosseini, M. List +11 more
2019Cancers23 citations Open access
Semantic Scholar
Lipid metabolism signatures in NASH-associated HCC.--letter.
S. Kessler, S. Laggai, A. Barghash, V. Helms +1 more
2014Cancer Research16 citations Open access
Semantic Scholar
Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation.
S. Kessler, J. Hoppstädter, Kevan Hosseini, S. Laggai +2 more
2019Journal of Hepatology11 citations
Semantic Scholar
Alterations in the hepatocyte epigenetic landscape in steatosis
R. K. Maji, Beate Czepukojc, M. Scherer, S. Tierling +19 more
2023Epigenetics & Chromatin5 citations Open access
Semantic Scholar
Corrigendum: Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation
S. Kessler, S. Laggai, E. Van Wonterghem, Katja Gemperlein +6 more
2016Frontiers in Physiology3 citations Open access
Semantic Scholar
P0952 : Transient hepatic overexpression of the insuline-like growth factor 2 (IGF2) induces lipid droplet formation
S. Kessler, S. Laggai, E. Van Wonterghem, R. Vandenbroucke +3 more
20151 citations
Semantic Scholar
Discovery of the First Small Molecules Targeting the RNA Binding Protein IGF2BP2/IMP2 as Potential Target in Cancer Therapy
Ali Abuhaliema, S. Kessler, C. Dahlem, Tarek Kröhler +6 more
2020Social Science Research Network0 citations
Semantic Scholar
THU-470-The mRNA-binding protein tristetraprolin promotes hepatocarcinogenesis but inhibits tumour progression in liver cancer
S. Kessler, Kevan Hosseini, Tarek Kröhler, A. Barghash +11 more
2019Journal of Hepatology0 citations
Semantic Scholar
2017A Schultheiss Cell Stress
Christina S. Schultheiss, S. Laggai, Beate Czepukojc, U. K. Hussein +18 more
20170 citations
Semantic Scholar
Erratum to “Hepatic hepcidin expression is decreased in cirrhosis and HCC” [J Hepatol 2015;62:977–979]
S. Kessler, A. Barghash, S. Laggai, V. Helms +1 more
20150 citations
Semantic Scholar
Hepatic steatosis and cancer development : role of insulin-like growth factor 2 mRNA binding protein p62 / IGF2BP2 / IMP2-2 and fatty acid elongase ELOVL6
S. Laggai
20140 citations
Semantic Scholar
1270 ALTERED FATTY ACID PROFILE IN LIVERS OVEREXPRESSING THE Igf2 mRNA BINDING PROTEIN p62: INDUCTION OF FATTY ACID ELONGASE ELOVL6 VIA Igf2-DEPENDENT SREBP1 ACTIVATION
S. Laggai, S. Kessler, Katja Gemperlein, J. Haybaeck +2 more
20130 citations Open access
Semantic Scholar
to: ‘‘Hepatic hepcidin expression is decreased in cirrhosis and HCC’’
S. Laggai, A. Kiemer, A. Barghash, M. Lunova +3 more
0 citations
Semantic Scholar

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A. Kiemer×22
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A. Kiemer — researcher profile on SciRah
S. Kessler×21
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J. Haybaeck×10
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A. Barghash×8
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Kevan Hosseini×7

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Marcel H. Schulz×6

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J. Hoppstädter×5

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