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Y. Aikawa · SciRah

Researcher profile · Semantic Scholar

Y. Aikawa

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Y. Aikawa — researcher profile on SciRah

h-index: 15
Works: 30
Citations: 1,341

Most-cited papers

Activation of AML1‐mediated transcription by MOZ and inhibition by the MOZ–CBP fusion protein
I. Kitabayashi, Y. Aikawa, L. Nguyen, A. Yokoyama +1 more
2001EMBO Journal241 citations Open access
Semantic Scholar
MOZ is essential for maintenance of hematopoietic stem cells.
Takuo Katsumoto, Y. Aikawa, A. Iwama, Shinobu Ueda +3 more
2006Genes & Development223 citations Open access
Semantic Scholar
Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation
I. Kitabayashi, Y. Aikawa, A. Yokoyama, F. Hosoda +4 more
2001Leukemia173 citations Open access
Semantic Scholar
Roles of HIPK1 and HIPK2 in AML1‐ and p300‐dependent transcription, hematopoiesis and blood vessel formation
Y. Aikawa, L. Nguyen, K. Isono, N. Takakura +4 more
2006EMBO Journal139 citations Open access
Semantic Scholar
PU.1-mediated upregulation of M-CSFR is critical for MOZ-leukemia stem cell potential
Y. Aikawa, Takuo Katsumoto, Pu Zhang, Haruko Shima +8 more
2010Nature Medicine92 citations Open access
Semantic Scholar
Monocytic Leukemia Zinc Finger (MOZ) Interacts with p53 to Induce p21 Expression and Cell-cycle Arrest*
Susumu Rokudai, Y. Aikawa, Y. Tagata, N. Tsuchida +2 more
2009Journal of Biological Chemistry84 citations Open access
Semantic Scholar
Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription
X.-L. Li, Y. Arai, H. Harada, Y. Shima +5 more
2007Oncogene74 citations Open access
Semantic Scholar
Selective inhibition of mutant IDH1 by DS-1001b ameliorates aberrant histone modifications and impairs tumor activity in chondrosarcoma
M. Nakagawa, F. Nakatani, Hironori Matsunaga, T. Seki +24 more
2019Oncogene67 citations Open access
Semantic Scholar
IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia.
Y. Ogawara, Takuo Katsumoto, Y. Aikawa, Y. Shima +6 more
2015Cancer Research53 citations Open access
Semantic Scholar
Physical and functional link of the leukemia-associated factors AML1 and PML.
L. Nguyen, P. Pandolfi, Y. Aikawa, Y. Tagata +2 more
2005Blood45 citations
Semantic Scholar
Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ–TIF2 fusion
Haruko Shima, Kazutsune Yamagata, Y. Aikawa, Mika Shino +3 more
2013International journal of hematology35 citations
Semantic Scholar
Ring1A and Ring1B inhibit expression of Glis2 to maintain murine MOZ-TIF2 AML stem cells.
Haruko Shima, Emi Takamatsu-Ichihara, Mika Shino, Kazutsune Yamagata +5 more
2018Blood27 citations
Semantic Scholar
Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells
Y. Aikawa, Kazutsune Yamagata, Takuo Katsumoto, Y. Shima +6 more
2015Cancer Science19 citations Open access
Semantic Scholar
Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia
Kazutsune Yamagata, Mika Shino, Y. Aikawa, Shuhei Fujita +1 more
2021Leukemia18 citations
Semantic Scholar
MOZ is critical for the development of MOZ/MLL fusion–induced leukemia through regulation of Hoxa9/Meis1 expression
Takuo Katsumoto, Y. Ogawara, Kazutsune Yamagata, Y. Aikawa +3 more
2022Blood Advances15 citations Open access
Semantic Scholar
Nuclear export signal within CALM is necessary for CALM-AF10-induced leukemia
Mai Suzuki, Kazutsune Yamagata, Mika Shino, Y. Aikawa +3 more
2014Cancer Science11 citations Open access
Semantic Scholar
Trichothecenes produced by Fusarium species Fn 2B
Y. Ueno, Y. Aikawa, H. Okumura, Y. Sugiura +5 more
199710 citations Open access
Semantic Scholar
Dual inhibition of EZH1/2 induces cell cycle arrest of B cell acute lymphoblastic leukemia cells through upregulation of CDKN1C and TP53INP1
Jumpei Ito, Kazutsune Yamagata, Haruka Shinohara, Y. Shima +3 more
2022International journal of hematology7 citations
Semantic Scholar
Loss of NOL10 leads to impaired disease progression of NUP98::DDX10 leukemia
Y. Shima, Kazutsune Yamagata, Yoko Kuroki, Kazuki Sasaki +2 more
2025Leukemia4 citations Open access
Semantic Scholar
Physical and functional link of the leukemia-associated factors AML 1 and PML
L. Nguyen, P. Pandolfi, Y. Aikawa, Y. Tagata +1 more
20042 citations
Semantic Scholar
Leukemia-Associated MLL-AF10 Fusion Maintains an Active State of Chromatin on Its Target Genes By Recruiting Tip60
Kazutsune Yamagata, Y. Aikawa, Mika Shino, I. Kitabayashi
20151 citations
Semantic Scholar
Abstract 1569: The nuclear export signal (NES) within CALM is necessary for CALM-AF10-induced leukemia
Mai Suzuki, Kazutsune Yamagata, Y. Aikawa, Toshio Watanabe +1 more
20141 citations
Semantic Scholar
Critical Roles Of The IDH2 Mutation In Development and Maintenance Of Acute Myeloid Leukemia
Takuo Katsumoto, Y. Aikawa, Y. Shima, Yuki Kagiyama +3 more
20131 citations
Semantic Scholar
Enhancer of zeste 2 polycomb repressive complex 2 subunit overexpression suppresses apoptosis in canine T-cell lymphoma: an in vitro functional analysis
Honoka Kawamura, Rina Ishikawa-Shinohara, Asuka Okamura, S. Kohno +8 more
2026Frontiers in Veterinary Science0 citations Open access
Semantic Scholar
CTCF Is Essential for the Development and Maintenance of CALM‐AF10‐Induced Leukemia
Yoko Kuroki, Kazutsune Yamagata, Y. Aikawa, Y. Shima +2 more
2025Cancer Science0 citations Open access
Semantic Scholar
変異型IDH1阻害剤は変異型IDH1を有する膠芽腫患者組織片皮下移植(PDX)モデルの腫瘍増殖を抑制する
Yukino Machida, Oga Yoko, Masayuki Yamaguchi, Kazutsune Yamagata +9 more
20160 citations
Semantic Scholar
NPMC cooperates with mutant IDH2 to induce acute myeloid leukemia
Y. Ogawara, Takuo Katsumoto, Y. Aikawa, Yuki Kagiyama +1 more
20130 citations Open access
Semantic Scholar
Roles of Ring1A/B on Stem Cell Potential of MOZ and Other Acute Myeloid Leukemias,
Haruko Shima, Mika Shino, Kazutsune Yamagata, Y. Aikawa +2 more
20110 citations
Semantic Scholar
PU.1-Mediated Upregulation of M-CSFR Is Critical for MOZ-Leukemia Stem Cell Potential.
Y. Aikawa, Takuo Katsumoto, D. Tenen, I. Kitabayashi
20090 citations
Semantic Scholar
MOZ interacts with p53 to induce p21 expression and cell-cycle arrest
Susumu Rokudai, Y. Aikawa, Y. Tagata, N. Tsuchida +3 more
20080 citations
Semantic Scholar

Frequent co-authors

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I. Kitabayashi×25
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I. Kitabayashi — researcher profile on SciRah
Kazutsune Yamagata×14
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Kazutsune Yamagata — researcher profile on SciRah
Takuo Katsumoto×11
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Mika Shino×8
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Y. Shima — researcher profile on SciRah

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Y. Tagata — researcher profile on SciRah

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L. Nguyen — researcher profile on SciRah

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M. Ohki — researcher profile on SciRah

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Haruko Shima×4

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Hironori Matsunaga×4

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Hironori Matsunaga — researcher profile on SciRah

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T. Seki — researcher profile on SciRah