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C. Lowell · SciRah

Researcher profile · Semantic Scholar

C. Lowell

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C. Lowell — researcher profile on SciRah

h-index: 97
Works: 300
Citations: 28K

Most-cited papers

The Multifaceted Functions of Neutrophils
T. Mayadas, X. Cullere, C. Lowell
2013Annual Review of Pathology1,279 citations Open access
Semantic Scholar
Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice
C. Abram, Gray L Roberge, Yongmei Hu, C. Lowell
2014JIM - Journal of Immunological Methods462 citations Open access
Semantic Scholar
SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin
Jun Chen, Ming-Chao Zhong, Huai-Jian Guo, D. Davidson +13 more
2017Nature266 citations Open access
Semantic Scholar
Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma.
J. Rubenstein, H. Geng, E. Fraser, P. Formaker +16 more
2018Blood Advances188 citations Open access
Semantic Scholar
Neutrophils in acute inflammation: current concepts and translational implications
A. Margraf, C. Lowell, A. Zarbock
2021Blood177 citations Open access
Semantic Scholar
Neutrophils: Their Role in Innate and Adaptive Immunity
C. Rosales, N. Demaurex, C. Lowell, E. Uribe-Querol
2016Journal of Immunological Research157 citations Open access
Semantic Scholar
Intracellular signalling during neutrophil recruitment
A. Mócsai, B. Walzog, C. Lowell
2015Cardiovascular Research145 citations Open access
Semantic Scholar
The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment
M. Kovács, T. Németh, Z. Jakus, C. Sitaru +6 more
2014Journal of Experimental Medicine144 citations Open access
Semantic Scholar
Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils.
Karim Mahiddine, Adam Blaisdell, Stephany Ma, A. Créquer-Grandhomme +2 more
2019Journal of Clinical Investigation120 citations Open access
Semantic Scholar
ROS-Triggered Phosphorylation of Complex II by Fgr Kinase Regulates Cellular Adaptation to Fuel Use
R. Acín-Pérez, Isabel Carrascoso, Francesc Baixauli, M. Roche-Molina +8 more
2014Cell Metabolism120 citations Open access
Semantic Scholar
Splenic dendritic cells survey red blood cells for missing self-CD47 to trigger adaptive immune responses
T. Yi, Jian-Hua Li, Hsin Chen, Jiaxi Wu +5 more
2015Immunity111 citations Open access
Semantic Scholar
Actin cytoskeleton reorganization by the tyrosine kinase Syk regulates Fcγ receptor responsiveness by increasing its lateral mobility and clustering
Valentin Jaumouillé, Y. Farkash, K. Jaqaman, Raibatak Das +2 more
2014Developmental Cell103 citations Open access
Semantic Scholar
Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells
Katharina Thomas, L. Zondler, Nadine Ludwig, Marina Kardell +19 more
2022JCI Insight102 citations Open access
Semantic Scholar
Molecular Editing of Cellular Responses by the High Affinity Receptor for IgE
R. Suzuki, S. Leach, Wenhua Liu, E. Ralston +4 more
2014Science102 citations Open access
Semantic Scholar
The Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile Inflammation
Stephanie Volmering, Helena Block, M. Boras, C. Lowell +1 more
2016Immunity99 citations Open access
Semantic Scholar
Leishmania uses Mincle to target an inhibitory ITAM signaling pathway in dendritic cells that dampens adaptive immunity to infection
S. Iborra, María Martínez-López, F. J. Cueto, Ruth Conde-Garrosa +12 more
2016Immunity97 citations Open access
Semantic Scholar
Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia
Zhengshan Chen, Seyedmehdi Shojaee, M. Buchner, H. Geng +22 more
2015Nature89 citations Open access
Semantic Scholar
Neutrophils: Their Role in Innate and Adaptive Immunity 2017
C. Rosales, C. Lowell, M. Schnoor, E. Uribe-Querol
2017Journal of Immunological Research77 citations Open access
Semantic Scholar
Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression
A. Poh, C. Love, F. Masson, Adele Preaudet +11 more
2017Cancer Cell77 citations Open access
Semantic Scholar
PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS STIM 1 calcium sensor is required for activation of the phagocyte oxidase during in fl ammation and host defense
Hong Zhang, R. Clemens, Feng-Chun Liu, Yongmei Hu +4 more
201469 citations
Semantic Scholar
Store‐operated calcium signaling in neutrophils
R. Clemens, C. Lowell
2015Journal of Leukocyte Biology68 citations Open access
Semantic Scholar
STIM1 and STIM2 cooperatively regulate mouse neutrophil store-operated calcium entry and cytokine production.
R. Clemens, J. Chong, Derayvia Grimes, Yongmei Hu +1 more
2017Blood66 citations Open access
Semantic Scholar
A critical role for Lyn kinase in strengthening endothelial integrity and barrier function.
Jing-Yan Han, Guoying Zhang, Emily J. Welch, Ying-Jian Liang +7 more
2013Blood65 citations Open access
Semantic Scholar
CRAC channel regulation of innate immune cells in health and disease
R. Clemens, C. Lowell
2019Cell Calcium63 citations Open access
Semantic Scholar
Prospective Study on the Clinical Course and Outcomes in Transfusion-Related Acute Lung Injury
M. Looney, N. Roubinian, O. Gajic, M. Gropper +18 more
2014Critical Care Medicine61 citations Open access
Semantic Scholar
Skap2 is required for β2 integrin–mediated neutrophil recruitment and functions
M. Boras, Stephanie Volmering, A. Bokemeyer, J. Rossaint +8 more
2017Journal of Experimental Medicine55 citations Open access
Semantic Scholar
Complement activation on endothelium initiates antibody-mediated acute lung injury.
S. Cleary, N. Kwaan, Jennifer J. Tian, D. Calabrese +14 more
2020Journal of Clinical Investigation49 citations Open access
Semantic Scholar
ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense
Derayvia Grimes, Ryan Johnson, Madeline Pashos, Celeste L. Cummings +7 more
2020Proceedings of the National Academy of Sciences of the United States of America49 citations Open access
Semantic Scholar
Isolation of Highly Pure Primary Mouse Alveolar Epithelial Type II Cells by Flow Cytometric Cell Sorting
M. Sinha, C. Lowell
2016Bio-protocol48 citations Open access
Semantic Scholar
Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity
Darienne R. Myers, C. Abram, D. Wildes, Amira Belwafa +12 more
2020Frontiers in Immunology47 citations Open access
Semantic Scholar
FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection
Sheena C. Kerr, Gregory J. Fischer, M. Sinha, Orla McCabe +10 more
2016PLoS Pathogens46 citations Open access
Semantic Scholar
Neutrophils in animal models of autoimmune disease
T. Németh, A. Mócsai, C. Lowell
2016Seminars in Immunology41 citations Open access
Semantic Scholar
Complement Activation and Intraventricular Rituximab Distribution in Recurrent Central Nervous System Lymphoma
C. Kadoch, Jing Li, V. Wong, Ling-Jing Chen +5 more
2013Clinical Cancer Research41 citations Open access
Semantic Scholar
LynA regulates an inflammation-sensitive signaling checkpoint in macrophages
T. Freedman, Y. Tan, Katarzyna M. Skrzypczynska, Boryana N. Manz +4 more
2015eLife37 citations Open access
Semantic Scholar
Lung Ischemia Reperfusion (IR) is a Sterile Inflammatory Process influenced by Commensal Microbiota in Mice
A. Prakash, Shirin V. Sundar, Ying-Gang Zhu, Alphonso Tran +3 more
2015Shock36 citations Open access
Semantic Scholar
CARD9 mediates dendritic cell-induced development of Lyn-deficiency–associated autoimmune and inflammatory diseases
Jun Ma, C. Abram, Yongmei Hu, C. Lowell
2019Science Signaling34 citations Open access
Semantic Scholar
The Src-family kinases Hck and Fgr regulate early lipopolysaccharide-induced myeloid cell recruitment into the lung and their ability to secrete chemokines
P. Mazzi, E. Caveggion, José A. Lapinet-Vera, C. Lowell +1 more
2015Journal of Immunology34 citations Open access
Semantic Scholar
Src family kinase-mediated vesicle trafficking is critical for neutrophil basement membrane penetration
I. Rohwedder, A. Kurz, M. Pruenster, R. Immler +9 more
2019Haematologica33 citations Open access
Semantic Scholar
L-selectin shedding affects bacterial clearance in the lung - a new regulatory pathway for integrin-outside-in signaling.
A. Cappenberg, A. Margraf, Katharina Thomas, Bernadette Bardel +5 more
2019Blood31 citations Open access
Semantic Scholar
Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice
A. Poh, A. Dwyer, M. Eissmann, A. Chand +10 more
2020Cancer immunology research29 citations Open access
Semantic Scholar
Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy
A. Poh, C. Love, D. Chisanga, J. Steer +19 more
2022Science Advances27 citations Open access
Semantic Scholar
Spleen tyrosine kinase facilitates neutrophil activation and worsens long-term neurologic deficits after spinal cord injury
D. McCreedy, C. Abram, Yongmei Hu, Sun Won Min +5 more
2021Journal of Neuroinflammation27 citations Open access
Semantic Scholar
A Neutrophil Subset Defined by Intracellular Olfactomedin 4 is Associated with Mortality in Sepsis.
K. Kangelaris, R. Clemens, Xiao-Hui Fang, A. Jauregui +12 more
2020American Journal of Physiology - Lung cellular and Molecular Physiology27 citations Open access
Semantic Scholar
DOWNREGULATION OF THE SYK SIGNALLING PATHWAY IN INTESTINAL DENDRITIC CELLS IS SUFFICIENT TO INDUCE DENDRITIC CELLS THAT INHIBIT COLITIS
L. Hang, A. Blum, Sangeeta Kumar, J. Urban +6 more
2016Journal of Immunology25 citations Open access
Semantic Scholar
A CD22-Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity
Romain Ballet, Martin Brennan, Caroline Brandl, N. Feng +14 more
2021Nature Immunology24 citations Open access
Semantic Scholar
LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.
Irina Proekt, Corey N. Miller, M. Jeanne, Kayla J. Fasano +5 more
2016Journal of Clinical Investigation23 citations Open access
Semantic Scholar
Crosstalk between Shp1 and PIPKIγ controls leukocyte recruitment.
Anika Stadtmann, Helena Block, Stephanie Volmering, C. Abram +4 more
2015Journal of Immunology23 citations Open access
Semantic Scholar
Immune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells.
M. Sinha, C. Lowell
2016American Journal of Respiratory Cell and Molecular Biology20 citations Open access
Semantic Scholar
Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9
Linda M. Lee, M. Ji, M. Sinha, Matthew B. Dong +6 more
2016PLoS ONE20 citations Open access
Semantic Scholar
Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis
A. Poh, M. O'Brien, D. Chisanga, Hong He +13 more
2022Cell Reports17 citations Open access
Semantic Scholar

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C. Abram — researcher profile on SciRah
Yongmei Hu×7
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Yongmei Hu — researcher profile on SciRah
A. Zarbock×6
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A. Zarbock — researcher profile on SciRah
R. Clemens×6
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R. Clemens — researcher profile on SciRah

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M. Sinha — researcher profile on SciRah

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A. Mócsai — researcher profile on SciRah

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A. Poh — researcher profile on SciRah

L. Whitehead×4

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L. Whitehead — researcher profile on SciRah

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M. Ernst — researcher profile on SciRah

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A. Margraf — researcher profile on SciRah

Stephanie Volmering×3

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Stephanie Volmering — researcher profile on SciRah

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Helena Block — researcher profile on SciRah