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S. Ettenberg · SciRah

Researcher profile · Semantic Scholar

S. Ettenberg

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S. Ettenberg — researcher profile on SciRah

h-index: 27
Works: 58
Citations: 5,364

Most-cited papers

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1.
G. Levkowitz, H. Waterman, S. Ettenberg, M. Katz +8 more
1999Molecules and Cells1,056 citations Open access
Semantic Scholar
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines.
M. Keane, S. Ettenberg, M. Nau, E. Russell +1 more
1999Cancer Research619 citations
Semantic Scholar
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma.
M. Fulciniti, P. Tassone, T. Hideshima, S. Vallet +12 more
2007Blood411 citations Open access
Semantic Scholar
Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2.
M. Cuello, S. Ettenberg, A. Clark, M. Keane +4 more
2001Cancer Research396 citations
Semantic Scholar
Fas expression and function in normal and malignant breast cell lines.
Maccon M. Keane, S. Ettenberg, Geoffrey A. Lowrey, E. Russell +1 more
1996Cancer Research272 citations
Semantic Scholar
An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells
Qing Sheng, Xinggang Liu, E. Fleming, K. Yuan +16 more
2010Cancer Cell230 citations Open access
Semantic Scholar
Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies
S. Ettenberg, O. Charlat, Michael P. Daley, Shan-Ming Liu +24 more
2010Proceedings of the National Academy of Sciences of the United States of America181 citations Open access
Semantic Scholar
Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor.
A. Tan, Xiao-Wei Yang, S. Hewitt, Arlene W. Berman +13 more
2004Journal of Clinical Oncology181 citations
Semantic Scholar
WW Domain HECT E3s Target Cbl RING Finger E3s for Proteasomal Degradation*
Alessandra Magnifico, S. Ettenberg, Cui-Hong Yang, J. Mariano +4 more
2003Journal of Biological Chemistry178 citations Open access
Semantic Scholar
Cbl-b-dependent Coordinated Degradation of the Epidermal Growth Factor Receptor Signaling Complex*
S. Ettenberg, Alessandra Magnifico, Mauricio Cuello, M. Nau +4 more
2001Journal of Biological Chemistry160 citations Open access
Semantic Scholar
Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells.
Mauricio Cuello, S. Ettenberg, M. Nau, S. Lipkowitz
2001Gynecologic Oncology159 citations
Semantic Scholar
The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells.
Maccon M. Keane, Geoffrey A. Lowrey, S. Ettenberg, M. Dayton +1 more
1996Cancer Research154 citations
Semantic Scholar
cbl-b inhibits epidermal growth factor receptor signaling
S. Ettenberg, M. Keane, M. Nau, Mark Frankel +3 more
1999Oncogene131 citations
Semantic Scholar
cbl-3: a new mammalian cbl family protein
M. Keane, S. Ettenberg, M. Nau, P. Banerjee +3 more
1999Oncogene128 citations Open access
Semantic Scholar
An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin
A. Garner, C. U. Bialucha, E. Sprague, J. Garrett +25 more
2013Cancer Research119 citations Open access
Semantic Scholar
Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b
G. C. Davies, S. Ettenberg, A. O. Coats, Mark Mussante +4 more
2004Oncogene105 citations
Semantic Scholar
Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction
Heather A. Huet, J. Growney, Jennifer A. Johnson, Jing Li +17 more
2014mAbs100 citations Open access
Semantic Scholar
Inhibition of NF-κB Activity Enhances TRAIL Mediated Apoptosis in Breast Cancer Cell Lines
M. Keane, Y. Rubinstein, M. Cuello, S. Ettenberg +3 more
2000Breast Cancer Research and Treatment91 citations
Semantic Scholar
Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110α inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers
J. Garrett, Cammie R. Sutton, Richard Kurupi, C. U. Bialucha +6 more
2013Cancer Research85 citations Open access
Semantic Scholar
Characterization of activating mutations of NOTCH3 in T cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies
Paula Bernasconi-Elias, T. Hu, David Jenkins, B. Firestone +24 more
2016Oncogene81 citations Open access
Semantic Scholar
Reversing LRP5‐Dependent Osteoporosis and SOST Deficiency–Induced Sclerosing Bone Disorders by Altering WNT Signaling Activity
Ming K. Chang, I. Kramer, Hansjoerg Keller, J. Gooi +6 more
2014Journal of Bone and Mineral Research74 citations Open access
Semantic Scholar
Targeting IL-17A in Multiple Myeloma: A Potential Novel Therapeutic Approach in Myeloma
R. Prabhala, M. Fulciniti, Dheeraj Pelluru, N. Rashid +17 more
2015Leukemia73 citations Open access
Semantic Scholar
cbl-b inhibits EGF-receptor-induced apoptosis by enhancing ubiquitination and degradation of activated receptors.
S. Ettenberg, Y. Rubinstein, P. Banerjee, M. Nau +2 more
1999Molecular Cell Biology Research Communications58 citations
Semantic Scholar
Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.
C. U. Bialucha, S. Collins, Xiao Li, Parmita Saxena +41 more
2017Cancer Discovery51 citations
Semantic Scholar
Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines.
M. Keane, Y. Rubinstein, M. Cuello, S. Ettenberg +3 more
2000Breast Cancer Research and Treatment48 citations
Semantic Scholar
N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines
M. Cuello, A. O. Coats, I. Darko, S. Ettenberg +5 more
2004Cell Death and Differentiation43 citations
Semantic Scholar
BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved anti-cell line derived tumor xenograft activity
Taylor L Hickman, Eugene Choi, K. Whiteman, S. Muralidharan +12 more
2022PLoS ONE34 citations Open access
Semantic Scholar
A Phase I/II Study of BHQ880, a Novel Osteoblat Activating, Anti-DKK1 Human Monoclonal Antibody, in Relapsed and Refractory Multiple Myeloma (MM) Patients Treated with Zoledronic Acid (Zol) and Anti-Myeloma Therapy (MM Tx).
S. Padmanabhan, J. Beck, K. Kelly, N. Munshi +14 more
200922 citations
Semantic Scholar
Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates
Kalli C. Catcott, M. McShea, C. U. Bialucha, K. Miller +10 more
2016mAbs19 citations Open access
Semantic Scholar
The ras suppressor, RSU-1, enhances nerve growth factor-induced differentiation of PC12 cells and induces p21CIP expression.
L. Masuelli, S. Ettenberg, F. Vasaturo, K. Vestergaard-Sykes +1 more
1999Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research15 citations
Semantic Scholar
Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages
Anupama Reddy, J. Growney, Nick Wilson, Caroline M. Emery +17 more
2015PLoS ONE14 citations Open access
Semantic Scholar
Target Cbl RING Finger E 3 s for Proteasomal Degradation *
Alessandra Magnifico, S. Ettenberg, Cui-Hong Yang, J. Mariano +4 more
200312 citations
Semantic Scholar
Abstract 2733: LJM716: an anti-HER3 antibody that inhibits both HER2 and NRG driven tumor growth by trapping HER3 in the inactive conformation.
A. Garner, Q. Sheng, Uli Bialucha, Dong-Shu Chen +15 more
201210 citations
Semantic Scholar
Abstract 3853: TAS266, a novel tetrameric nanobody agonist targeting death receptor 5 (DR5), elicits superior antitumor efficacy than conventional DR5-targeted approaches
Heather A. Huet, A. Schuller, Jing Li, Jennifer A. Johnson +14 more
20129 citations
Semantic Scholar
Ovarian Cancer Cell Lines that Overexpress erbB2 Apoptosis-inducing Ligand-mediated Apoptosis in Breast and ( Herceptin ) Enhances Tumor Necrosis Factor-related Down-Regulation of the erbB2 Receptor by Trastuzumab
M. Cuello, S. Ettenberg, A. Clark, M. Keane +4 more
20019 citations
Semantic Scholar
Abstract 4261: Targeting HER3 and PI3K in head and neck squamous cancer cells.
Q. Sheng, Hui-Qin Wang, R. Das, Yan Chen +5 more
20137 citations
Semantic Scholar
BHQ880, a novel anti-DKK1 neutralizing antibody, inhibits tumor-induced osteolytic bone disease
S. Ettenberg, Feng Cong, J. Shulok, S. Urlinger +13 more
20086 citations
Semantic Scholar
Elevated serum M-CSF level predicts reduced survival in metastatic breast cancer patients
K. Leitzel, S. Ettenberg, R. Walsh, J. Abraham +6 more
20075 citations
Semantic Scholar
ACTR087, Autologous T Lymphocytes Expressing Antibody Coupled T-Cell Receptors (ACTR), Induces Complete Responses in Patients with Relapsed or Refractory CD20-Positive B-Cell Lymphoma, in Combination with Rituximab
L. Akard, S. Jaglowski, S. Devine, Matthew Mckinney +5 more
20174 citations
Semantic Scholar
Abstract B105: ACTR707: a novel T-cell therapy for the treatment of relapsed or refractory CD20+ B cell lymphoma in combination with rituximab
G. Motz, K. Whiteman, John H. Shin, Tapasya Pai +11 more
20183 citations
Semantic Scholar
Adaptability of Antibody-Coupled T Cell Receptor (ACTR) Engineered Autologous T Cells in Combination with Daratumumab over CAR-Based Approaches
Taylor L Hickman, Adrianna Graziano, Katie M. O'Callaghan, Ryan M. Boomer +7 more
20173 citations
Semantic Scholar
BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved antitumor activity
Taylor L Hickman, Eugene Choi, K. Whiteman, S. Muralidharan +12 more
2021bioRxiv2 citations Open access
Semantic Scholar
Targeting CD20+ Relapsed Refractory B Cell Lymphoma with ACTR087, Antibody-Coupled T-Cell Receptor (ACTR) Engineered Autologous T Cells, in Combination with Rituximab
Heather A. Huet, C. Judge, R. A. Barnitz, Ryan M. Boomer +10 more
20162 citations
Semantic Scholar
Human Monoclonal Antibody Targeting IL-17A (AIN457) Down-Regulates MM Cell-Growth and Survival and Inhibits Osteoclast Development In Vitro and In Vivo: A Potential Novel Therapeutic Application In Myeloma
R. Prabhala, M. Fulciniti, Dheeraj Pelluru, P. Nanjappa +14 more
20102 citations
Semantic Scholar
The Ras suppressor, Rsu-1, enhances NGF-induced differentiation of PC12 cells by induction of p21CIP
L. Masuelli, S. Ettenberg, F. Vasaturo, K. Sykes +1 more
19992 citations
Semantic Scholar
Fas expression and function in normal and malignant cell lines
M. Keane, S. Ettenberg, Geoffrey A. Lowrey, E. Russell +1 more
19962 citations
Semantic Scholar
Abstract 2184: BOXR1030: A first-in-class CAR T-cell therapy co-expressing GOT2 enhances T-cell metabolic function for the treatment of GPC3-positive solid tumors
Eugene Choi, K. Whiteman, Tapasya Pai, Taylor L Hickman +9 more
2020Immunology1 citations
Semantic Scholar
Abstract 4605: Efficient targeting of BCMA-positive multiple myeloma cells by antibody-coupled T-cell receptor (ACTR) engineered autologous T cells in combination with an anti-BCMA antibody
T. Cheema, Taylor L Hickman, Katie M. O'Callaghan, Lori Westendorf +9 more
20171 citations
Semantic Scholar
CR064, a fully human monoclonal antibody to angiopoietin related protein 4 (ARP4) inhibits ARP4-mediated angiogenesis and renal cell carcinoma survival in vitro
H. Zhong, S. Ettenberg, M. Dhanabal, M. Baron +6 more
20051 citations
Semantic Scholar
Regulation of Epidermal Growth Factor Receptor Signaling by cbl-b
S. Ettenberg
20011 citations
Semantic Scholar

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