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J. Metcalf · SciRah

Researcher profile · Semantic Scholar

J. Metcalf

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J. Metcalf — researcher profile on SciRah

h-index: 60
Works: 139
Citations: 14K

Most-cited papers

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
S. Migueles, Alisha C. Laborico, W. Shupert, M. Sabbaghian +10 more
2002Nature Immunology1,119 citations
Semantic Scholar
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression.
R. Davey, N. Bhat, C. Yoder, Tae-Wook Chun +16 more
1999Proceedings of the National Academy of Sciences of the United States of America868 citations Open access
Semantic Scholar
New Real-Time Reverse Transcriptase-Initiated PCR Assay with Single-Copy Sensitivity for Human Immunodeficiency Virus Type 1 RNA in Plasma
S. Palmer, A. Wiegand, F. Maldarelli, Holly Z. Bazmi +8 more
2003Journal of Clinical Microbiology622 citations Open access
Semantic Scholar
Multiple, Linked Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Treatment-Experienced Patients Are Missed by Standard Genotype Analysis
S. Palmer, M. Kearney, F. Maldarelli, E. Halvas +10 more
2005Journal of Clinical Microbiology530 citations Open access
Semantic Scholar
Effect of interleukin-2 on the pool of latently infected, resting CD4+ T cells in HIV-1-infected patients receiving highly active anti-retroviral therapy
Tae-Wook Chun, D. Engel, S. Mizell, C. Hallahan +11 more
1999Nature Medicine429 citations
Semantic Scholar
ART Suppresses Plasma HIV-1 RNA to a Stable Set Point Predicted by Pretherapy Viremia
F. Maldarelli, S. Palmer, M. King, A. Wiegand +14 more
2007PLoS Pathogens344 citations Open access
Semantic Scholar
Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV Infection1
D. Douek, M. Betts, B. Hill, S. Little +11 more
2001Journal of Immunology281 citations Open access
Semantic Scholar
Identification of Dynamically Distinct Subpopulations of T Lymphocytes That Are Differentially Affected by HIV
J. Kovacs, R. Lempicki, I. Sidorov, J. Adelsberger +16 more
2001Journal of Experimental Medicine246 citations Open access
Semantic Scholar
Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection.
Robert E. Walker, C. Bechtel, V. Natarajan, M. Baseler +18 more
2000Blood238 citations
Semantic Scholar
Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy
D. McMahon, J. Jones, A. Wiegand, S. Gange +9 more
2010Clinical Infectious Diseases231 citations Open access
Semantic Scholar
Diminished Proliferation of Human Immunodeficiency Virus-Specific CD4+ T Cells Is Associated with Diminished Interleukin-2 (IL-2) Production and Is Recovered by Exogenous IL-2
Christiana Iyasere, J. Tilton, A. Johnson, Souheil-Antoine Younes +12 more
2003Journal of Virology221 citations Open access
Semantic Scholar
Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4+ and CD8+ T cell turnover in HIV-infected patients.
R. Lempicki, J. Kovacs, M. Baseler, J. Adelsberger +11 more
2000Proceedings of the National Academy of Sciences of the United States of America214 citations Open access
Semantic Scholar
Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy
S. Migueles, K. A. Weeks, Eric Nou, Amy M. Berkley +10 more
2009Journal of Virology203 citations Open access
Semantic Scholar
The Differential Ability of HLA B*5701+ Long-Term Nonprogressors and Progressors To Restrict Human Immunodeficiency Virus Replication Is Not Caused by Loss of Recognition of Autologous Viral gag Sequences
S. Migueles, Alisha C. Laborico, H. Imamichi, W. Shupert +7 more
2003Journal of Virology180 citations Open access
Semantic Scholar
High dose atorvastatin decreases cellular markers of immune activation without affecting HIV-1 RNA levels: results of a double-blind randomized placebo controlled clinical trial.
A. Ganesan, N. Crum-Cianflone, J. Higgins, Jing Qin +10 more
2011Journal of Infectious Diseases162 citations Open access
Semantic Scholar
Short-cycle structured intermittent treatment of chronic HIV infection with highly active antiretroviral therapy: Effects on virologic, immunologic, and toxicity parameters
M. Dybul, Tae-Wook Chun, C. Yoder, B. Hidalgo +15 more
2001Proceedings of the National Academy of Sciences of the United States of America159 citations Open access
Semantic Scholar
Idiopathic CD4 (cid:1) lymphocytopenia: natural history and prognostic factors
Dimitrios I. Zonios, J. Falloon, J. Bennett, P. Shaw +11 more
2008144 citations
Semantic Scholar
An IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in men infected with human immunodeficiency virus.
C. B. Foster, Thomas Lehrnbecher, Susan Samuels, S. Stein +8 more
2000Blood144 citations
Semantic Scholar
Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients.
J. Kovacs, R. Lempicki, I. Sidorov, J. Adelsberger +20 more
2005Journal of Clinical Investigation137 citations Open access
Semantic Scholar
Cutting Edge: L-Selectin (CD62L) Expression Distinguishes Small Resting Memory CD4+ T Cells That Preferentially Respond to Recall Antigen
R. Hengel, Vishakha Thaker, M. Pavlick, J. Metcalf +5 more
2003Journal of Immunology135 citations
Semantic Scholar
HIV Populations Are Large and Accumulate High Genetic Diversity in a Nonlinear Fashion
F. Maldarelli, M. Kearney, S. Palmer, R. Stephens +14 more
2013Journal of Virology131 citations Open access
Semantic Scholar
In vivo expansion of CD4+CD45RO–CD25+ T cells expressing foxP3 in IL-2-treated HIV-infected patients
I. Sereti, H. Imamichi, V. Natarajan, T. Imamichi +11 more
2005118 citations Open access
Semantic Scholar
Human immunodeficiency virus type 1 quasi species that rebound after discontinuation of highly active antiretroviral therapy are similar to the viral quasi species present before initiation of therapy.
H. Imamichi, K. Crandall, V. Natarajan, Min-Kang Jiang +7 more
2001Journal of Infectious Diseases118 citations
Semantic Scholar
Correlation between reduction in plasma HIV-1 RNA concentration 1 week after start of antiretroviral treatment and longer-term efficacy.
Michael A. Polis, I. Sidorov, C. Yoder, S. Jankelevich +6 more
2001The Lancet114 citations
Semantic Scholar
Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial
Richard T. Davey, Eduardo Fernández-Cruz, Norman Markowitz, S. Pett +149 more
2019The Lancet Respiratory Medicine108 citations Open access
Semantic Scholar
Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy
S. Palmer, V. Boltz, F. Maldarelli, M. Kearney +8 more
2006AIDS (London)108 citations Open access
Semantic Scholar
IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation.
I. Sereti, Kara B. Anthony, Hector Martinez-Wilson, R. Lempicki +7 more
2004Blood107 citations Open access
Semantic Scholar
Pre-ART Levels of Inflammation and Coagulation Markers Are Strong Predictors of Death in a South African Cohort with Advanced HIV Disease
L. Ledwaba, Jorge A. Tavel, Paul Khabo, P. Maja +9 more
2012PLoS ONE105 citations Open access
Semantic Scholar
Pre-HAART HIV burden approximates post-HAART viral levels following interruption of therapy in patients with sustained viral suppression
H. Hatano, S. Vogel, C. Yoder, J. Metcalf +3 more
2000AIDS (London)104 citations Open access
Semantic Scholar
A Randomized Study of Immune Plasma for the Treatment of Severe Influenza
J. Beigel, Pablo Tebas, M. Elie-Turenne, Ednan K. Bajwa +17 more
2017The Lancet Respiratory Medicine102 citations Open access
Semantic Scholar
Long-cycle structured intermittent versus continuous highly active antiretroviral therapy for the treatment of chronic infection with human immunodeficiency virus: effects on drug toxicity and on immunologic and virologic parameters.
M. Dybul, Elizabeth Nies-Kraske, M. Daucher, K. Hertogs +12 more
2003Journal of Infectious Diseases94 citations
Semantic Scholar
Human Immunodeficiency Virus Viremia Induces Plasmacytoid Dendritic Cell Activation In Vivo and Diminished Alpha Interferon Production In Vitro
J. Tilton, M. Manion, Marlise R. Luskin, A. Johnson +10 more
2008Journal of Virology92 citations Open access
Semantic Scholar
Pilot study of the effects of intermittent interleukin-2 on human immunodeficiency virus (HIV)-specific immune responses in patients treated during recently acquired HIV infection.
M. Dybul, B. Hidalgo, Tae-Wook Chun, M. Belson +9 more
2002Journal of Infectious Diseases91 citations Open access
Semantic Scholar
Changes in Paracrine Interleukin-2 Requirement, CCR7 Expression, Frequency, and Cytokine Secretion of Human Immunodeficiency Virus-Specific CD4+ T Cells Are a Consequence of Antigen Load
J. Tilton, Marlise R. Luskin, A. Johnson, M. Manion +5 more
2006Journal of Virology88 citations Open access
Semantic Scholar
Relative Replication Fitness of a High-Level 3′-Azido-3′-Deoxythymidine-Resistant Variant of Human Immunodeficiency Virus Type 1 Possessing an Amino Acid Deletion at Codon 67 and a Novel Substitution (Thr→Gly) at Codon 69
T. Imamichi, Steve C. Berg, H. Imamichi, J. López +3 more
2000Journal of Virology88 citations Open access
Semantic Scholar
Naïve T-Cell Dynamics in Human Immunodeficiency Virus Type 1 Infection: Effects of Highly Active Antiretroviral Therapy Provide Insights into the Mechanisms of Naïve T-Cell Depletion
M. Di Mascio, I. Sereti, Lynn T. Matthews, V. Natarajan +10 more
2006Journal of Virology77 citations Open access
Semantic Scholar
Lymph node architecture preceding and following 6 months of potent antiviral therapy: follicular hyperplasia persists in parallel with p24 antigen restoration after involution and CD4 cell depletion in an AIDS patient.
J. Orenstein, M. Feinberg, C. Yoder, L. Schrager +11 more
1999AIDS (London)76 citations Open access
Semantic Scholar
The effects of storage temperature on PBMC gene expression
Jun Yang, Norma Diaz, J. Adelsberger, Xue-Yuan Zhou +8 more
2016BMC Immunology75 citations Open access
Semantic Scholar
Diminished Production of Monocyte Proinflammatory Cytokines during Human Immunodeficiency Virus Viremia Is Mediated by Type I Interferons
J. Tilton, A. Johnson, Marlise R. Luskin, M. Manion +9 more
2006Journal of Virology75 citations Open access
Semantic Scholar
Systemic Inflammation, Coagulation, and Clinical Risk in the START Trial
J. Baker, Shweta Sharma, B. Grund, Adam W. Rupert +10 more
2017Open Forum Infectious Diseases74 citations Open access
Semantic Scholar
Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection
V. Natarajan, R. Lempicki, I. Sereti, Yunden Badralmaa +7 more
2002Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
The Association between Serum Biomarkers and Disease Outcome in Influenza A(H1N1)pdm09 Virus Infection: Results of Two International Observational Cohort Studies
R. Davey, R. Lynfield, D. Dwyer, M. Losso +13 more
2013PLoS ONE64 citations Open access
Semantic Scholar
In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients.
I. Sereti, H. Imamichi, V. Natarajan, T. Imamichi +11 more
2005Journal of Clinical Investigation63 citations
Semantic Scholar
Tuberculosis Risk Factors and Mortality for HIV Infected Persons Receiving Antiretroviral Therapy in South Africa
S. Komati, P. Shaw, N. Stubbs, M. J. Mathibedi +5 more
2010AIDS (London)62 citations Open access
Semantic Scholar
CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients
I. Sereti, B. Herpin, J. Metcalf, R. Stevens +5 more
2001AIDS (London)61 citations Open access
Semantic Scholar
Variant genotypes of FcγRIIIA influence the development of Kaposi's sarcoma in HIV-infected men
T. Lehrnbecher, C. B. Foster, Shao-Xia Zhu, D. Venzon +8 more
200060 citations
Semantic Scholar
Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells
M. Daucher, D. Price, J. Brenchley, L. Lamoreaux +10 more
2008Journal of Virology59 citations Open access
Semantic Scholar
Detection of KIR3DS1 on the Cell Surface of Peripheral Blood NK Cells Facilitates Identification of a Novel Null Allele and Assessment of KIR3DS1 Expression during HIV-1 Infection12
V. Pascal, Eriko Yamada, Maureen P. Martin, G. Alter +7 more
2007Journal of Immunology59 citations Open access
Semantic Scholar
A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection.
M. Dybul, Elizabeth Nies-Kraske, R. Dewar, F. Maldarelli +15 more
2004Journal of Infectious Diseases59 citations Open access
Semantic Scholar
Comparisons of CD8+ T Cells Specific for Human Immunodeficiency Virus, Hepatitis C Virus, and Cytomegalovirus Reveal Differences in Frequency, Immunodominance, Phenotype, and Interleukin-2 Responsiveness
Prasanna Jagannathan, C. M. Osborne, C. Royce, M. Manion +15 more
2009Journal of Virology58 citations Open access
Semantic Scholar

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