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Peter J. Wermuth · SciRah

Researcher profile · Semantic Scholar

Peter J. Wermuth

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Peter J. Wermuth — researcher profile on SciRah

h-index: 19
Works: 37
Citations: 1,233

Most-cited papers

The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases
Peter J. Wermuth, S. Jimenez
2015Clinical and Translational Medicine150 citations Open access
Semantic Scholar
Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases
E. Macarak, Peter J. Wermuth, J. Rosenbloom, J. Uitto
2020Experimental Dermatology126 citations
Semantic Scholar
Stimulation of Transforming Growth Factor-β1-Induced Endothelial-To-Mesenchymal Transition and Tissue Fibrosis by Endothelin-1 (ET-1): A Novel Profibrotic Effect of ET-1
Peter J. Wermuth, Zhao-Dong Li, F. Mendoza, S. Jimenez
2016PLoS ONE101 citations Open access
Semantic Scholar
INDUCTION OF EXPRESSION OF PROFIBROTIC CYTOKINES AND GROWTH FACTORS IN NORMAL HUMAN PERIPHERAL BLOOD MONOCYTES BY GADOLINIUM CONTRAST AGENTS
Peter J. Wermuth, F. del Galdo, S. Jimenez
2009Arthritis & Rheumatism85 citations Open access
Semantic Scholar
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.
Y. Pekarsky, M. Campiglio, Z. Siprashvili, T. Druck +10 more
1998Proceedings of the National Academy of Sciences of the United States of America76 citations Open access
Semantic Scholar
Exosomes isolated from serum of systemic sclerosis patients display alterations in their content of profibrotic and antifibrotic microRNA and induce a profibrotic phenotype in cultured normal dermal fibroblasts
Peter J. Wermuth, S. Piera-velázquez, S. Jimenez
2017Clinical and Experimental Rheumatology70 citations
Semantic Scholar
Desmoglein 2 modulates extracellular vesicle release from squamous cell carcinoma keratinocytes
Andrew M. Overmiller, Jennifer A. Pierluissi, Peter J. Wermuth, S. Sauma +8 more
2017The FASEB Journal63 citations Open access
Semantic Scholar
Caveolin-1 deficiency induces spontaneous endothelial-to-mesenchymal transition in murine pulmonary endothelial cells in vitro.
Zhao-Dong Li, Peter J. Wermuth, B. Benn, M. Lisanti +1 more
2013American Journal of Pathology59 citations Open access
Semantic Scholar
Existing and novel biomarkers for precision medicine in systemic sclerosis
Peter J. Wermuth, S. Piera-velázquez, J. Rosenbloom, S. Jimenez
2018Nature Reviews Rheumatology55 citations
Semantic Scholar
Gd compounds signaling through Toll-like receptors 4 and 7 in normal human macrophages: establishment of a proinflammatory phenotype and implications for the pathogenesis of Nephrogenic Systemic Fibrosis
Peter J. Wermuth, S. Jimenez
2012Journal of Immunology54 citations Open access
Semantic Scholar
miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas
J. Flemming, Brianna Hill, M. Haque, J. Raad +9 more
2020Journal of Extracellular Vesicles53 citations Open access
Semantic Scholar
Meis1-mediated apoptosis is caspase dependent and can be suppressed by coexpression of HoxA9 in murine and human cell lines.
Peter J. Wermuth, A. Buchberg
2005Blood50 citations Open access
Semantic Scholar
NFκB activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of nephrogenic systemic fibrosis
F. del Galdo, Peter J. Wermuth, S. Addya, P. Fortina +1 more
2010Annals of the Rheumatic Diseases39 citations Open access
Semantic Scholar
Persistent activation of dermal fibroblasts from patients with gadolinium-associated nephrogenic systemic fibrosis
S. Piera-velázquez, N. Louneva, Jolanta Fertala, Peter J. Wermuth +2 more
2010Annals of the Rheumatic Diseases37 citations Open access
Semantic Scholar
Induction of a type I interferon signature in normal human monocytes by gadolinium‐based contrast agents: comparison of linear and macrocyclic agents
Peter J. Wermuth, S. Jimenez
2014Clinical and Experimental Immunology35 citations Open access
Semantic Scholar
Mechanisms of extracellular vesicle uptake and implications for the design of cancer therapeutics
Stephanie R. Jackson Cullison, Joseph Flemming, K. Karagoz, Peter J. Wermuth +1 more
2024Journal of Extracellular Biology32 citations Open access
Semantic Scholar
Endothelial cell-specific activation of transforming growth factor-β signaling in mice induces cutaneous, visceral, and microvascular fibrosis
Peter J. Wermuth, K. Carney, F. Mendoza, S. Piera-velázquez +1 more
2017Laboratory investigation; a journal of technical methods and pathology27 citations Open access
Semantic Scholar
Effect of Protein Kinase C delta (PKC-δ) Inhibition on the Transcriptome of Normal and Systemic Sclerosis Human Dermal Fibroblasts In Vitro
Peter J. Wermuth, S. Addya, S. Jimenez
2011PLoS ONE27 citations Open access
Semantic Scholar
Abrogation of transforming growth factor-β-induced tissue fibrosis in mice with a global genetic deletion of Nox4
Peter J. Wermuth, F. Mendoza, S. Jimenez
2018Laboratory Investigation21 citations Open access
Semantic Scholar
Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib)
Peter J. Wermuth, S. Jimenez
2018PLoS ONE18 citations Open access
Semantic Scholar
Trametinib prevents mesothelial-mesenchymal transition and ameliorates abdominal adhesion formation.
E. Macarak, Christine Lotto, Deepika Koganti, Xiao-Ling Jin +4 more
2018Journal of Surgical Research18 citations Open access
Semantic Scholar
Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis
Morgan D. Basta, S. Petruk, Ross Summer, J. Rosenbloom +5 more
2023iScience12 citations Open access
Semantic Scholar
Identification of novel systemic sclerosis biomarkers employing aptamer proteomic analysis
Peter J. Wermuth, S. Piera-velázquez, S. Jimenez
2018Rheumatology11 citations
Semantic Scholar
Extracellular Vesicles in the Skin Microenvironment: Emerging Roles as Biomarkers and Therapeutic Tools in Dermatologic Health and Disease.
J. Flemming, Peter J. Wermuth, Mỹ G. Mahoney
2023Journal of Investigative Dermatology8 citations
Semantic Scholar
Chemical exposure-induced systemic fibrosing disorders: Novel insights into systemic sclerosis etiology and pathogenesis.
S. Piera-velázquez, Peter J. Wermuth, J. Gómez-Reino, J. Varga +1 more
2020Seminars in Arthritis & Rheumatism5 citations
Semantic Scholar
Molecular characteristics and functional differences of anti-PM/Scl autoantibodies and two other distinct and unique supramolecular structures known as “EXOSOMES”
Peter J. Wermuth, S. Jimenez
2020Autoimmunity Reviews4 citations Open access
Semantic Scholar
Caveolin-1 De fi ciency Induces Spontaneous Endothelial-to-Mesenchymal Transition in Murine Pulmonary Endothelial Cells in Vitro
Zhao-Dong Li, Peter J. Wermuth, B. Benn, M. Lisanti +1 more
20174 citations
Semantic Scholar
Nephrogenic Systemic Fibrosis
Peter J. Wermuth, S. Jimenez
20121 citations
Semantic Scholar
Translational Opportunity of Engineered IFNγ-eEVs Through Targeted Inhibition of JAK/STAT1 Signaling, Mimicking IVIg Therapy
Kylie E. Preihs, K. Karagoz, Claire R. Shuey, Amritha Achuthkumar +13 more
2026bioRxiv0 citations Open access
Semantic Scholar
Effects of Oxygen Manipulation on Myofibroblast Phenotypic Transformation in Patients With Radiation‐Induced Fibrosis
Eric V. Mastrolonardo, Sarah Sussman, Bo H Yun, Victor Jegede +6 more
2025Wound Repair and Regeneration0 citations
Semantic Scholar
Overview on Keloid Disorder: Phenotypic Spectrum, Connective Tissue Pathology, and Treatment Development
Shan Wang, Jie Yang, E. Macarak, Peter J. Wermuth +2 more
20200 citations Open access
Semantic Scholar
OP0096 Interferon signature in systemic sclerosis lung microvascular endothelial cells
F. Mendoza, S. Piera-velázquez, Peter J. Wermuth, S. Addya +2 more
20170 citations Open access
Semantic Scholar
490 The effect of Dsg2 in the SSC cells on exosome contents, release, and effects on recipient fibroblasts
A. Overmiller, J. Pierluissi, Peter J. Wermuth, U. Martinez-Outschoorn +6 more
20160 citations Open access
Semantic Scholar
422 Dsg2 increases exosome release and enhances EGFR/c-Src content: A mechanism for an intercellular mitogenic effect
A. Overmiller, J. Pierluissi, Peter J. Wermuth, U. Martinez-Outschoorn +3 more
20160 citations Open access
Semantic Scholar
Nephrogenic Systemic Fibrosis Implications for the Pathogenesis of Proinflammatory Phenotype and Macrophages: Establishment of a TLR 4 and TLR 7 in Normal Human Gadolinium Compounds Signaling through
Peter J. Wermuth, S. Jimenez
20150 citations
Semantic Scholar
Meis 1 at the boundary between life and death: the context of meis 1 expression can decide between survival and apoptosis
Peter J. Wermuth
20050 citations
Semantic Scholar
Mediated Apoptosis is Caspase-Dependent and can be Suppressed by Coexpression of HoxA 9 in Murine and Human Cell Lines Running Title : Meis 1-mediated apoptosis
Peter J. Wermuth, A. Buchberg
20040 citations
Semantic Scholar

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S. Piera-velázquez×7
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J. Rosenbloom×5
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E. Macarak×4
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Mỹ G. Mahoney×4

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Zhao-Dong Li×3

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