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Luca Massimino · SciRah

Researcher profile · Semantic Scholar

Luca Massimino

Ospedale San Raffaele

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Luca Massimino — researcher profile on SciRah

ORCID iD 0000-0003-3975-9148Homepage

h-index: 29
Works: 81
Citations: 2,909

Most-cited papers

Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson’s Disease Models
Angelo Iannielli, Simone Bido, Lucrezia Folladori, Alice Segnali +13 more
2018Cell Reports214 citations Open access
Semantic Scholar
Direct Conversion of Fibroblasts into Functional Astrocytes by Defined Transcription Factors
Massimiliano Caiazzo, S. Giannelli, P. Valente, G. Lignani +9 more
2014Stem Cell Reports203 citations Open access
Semantic Scholar
dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice.
G. Colasante, G. Lignani, S. Brusco, C. Di Berardino +15 more
2020Molecular Therapy202 citations Open access
Semantic Scholar
Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity
Simone Bido, Sharon Muggeo, Luca Massimino, M. Marzi +14 more
2021Nature Communications181 citations Open access
Semantic Scholar
Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming.
G. Colasante, G. Lignani, Alicia Rubio, L. Medrihan +17 more
2015Cell Stem Cell168 citations Open access
Semantic Scholar
Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery
S. Giannelli, Mirko Luoni, V. Castoldi, Luca Massimino +6 more
2018Human Molecular Genetics124 citations Open access
Semantic Scholar
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy
G. Colasante, Yichen Qiu, Luca Massimino, C. Di Berardino +10 more
2020Brain : a journal of neurology112 citations Open access
Semantic Scholar
SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub
R. Piazza, V. Magistroni, S. Redaelli, Mario Mauri +23 more
2018Nature Communications108 citations Open access
Semantic Scholar
Metagenomic analysis of intestinal mucosa revealed a specific eukaryotic gut virome signature in early-diagnosed inflammatory bowel disease
F. Ungaro, Luca Massimino, F. Furfaro, V. Rimoldi +3 more
2018Gut microbes100 citations Open access
Semantic Scholar
SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.
A. Sessa, L. Fagnocchi, G. Mastrototaro, Luca Massimino +12 more
2019Neuron96 citations Open access
Semantic Scholar
The Inflammatory Bowel Disease Transcriptome and Metatranscriptome Meta-Analysis (IBD TaMMA) framework
Luca Massimino, L. Lamparelli, Yashar Houshyar, S. D'Alessio +4 more
2021Nature Computational Science93 citations Open access
Semantic Scholar
Frataxin gene editing rescues Friedreich’s ataxia pathology in dorsal root ganglia organoid-derived sensory neurons
P. Mazzara, Sharon Muggeo, Mirko Luoni, Luca Massimino +16 more
2020Nature Communications80 citations Open access
Semantic Scholar
Activation of the VEGFC/VEGFR3 pathway induces tumor immune escape in colorectal cancer.
C. Tacconi, F. Ungaro, C. Correale, V. Arena +16 more
2019Cancer Research78 citations Open access
Semantic Scholar
Gut Dysbiosis in Irritable Bowel Syndrome: A Narrative Review on Correlation with Disease Subtypes and Novel Therapeutic Implications
M. Napolitano, E. Fasulo, F. Ungaro, Luca Massimino +3 more
2023Microorganisms77 citations Open access
Semantic Scholar
Lorlatinib Treatment Elicits Multiple On- and Off-Target Mechanisms of Resistance in ALK-Driven Cancer.
S. Redaelli, M. Ceccon, M. Zappa, G. Sharma +9 more
2018Cancer Research74 citations
Semantic Scholar
Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome
Nicholas Valassina, S. Brusco, Alessia Salamone, L. Serra +10 more
2022Nature Communications67 citations Open access
Semantic Scholar
Local insulin-like growth factor I expression is essential for Purkinje neuron survival at birth
L. Croci, V. Barili, D. Chia, Luca Massimino +5 more
2010Cell Death and Differentiation61 citations Open access
Semantic Scholar
The gut virome in inflammatory bowel disease pathogenesis: From metagenomics to novel therapeutic approaches
F. Ungaro, Luca Massimino, S. D'Alessio, S. Danese
2019United European Gastroenterology journal58 citations Open access
Semantic Scholar
MFSD2A Promotes Endothelial Generation of Inflammation-Resolving Lipid Mediators and Reduces Colitis in Mice.
F. Ungaro, C. Tacconi, Luca Massimino, P. Corsetto +19 more
2017Gastroenterology57 citations Open access
Semantic Scholar
Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome
Mirko Luoni, S. Giannelli, M. Indrigo, A. Niro +9 more
2019bioRxiv54 citations Open access
Semantic Scholar
ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine
D. Fontana, Mario Mauri, Rossella Renso, M. Docci +26 more
2020Nature Communications50 citations Open access
Semantic Scholar
SETBP1 accumulation induces P53 inhibition and genotoxic stress in neural progenitors underlying neurodegeneration in Schinzel-Giedion syndrome
Federica Banfi, Alicia Rubio, M. Zaghi, Luca Massimino +13 more
2021Nature Communications43 citations Open access
Semantic Scholar
TNF‐Stimulated Gene‐6 Is a Key Regulator in Switching Stemness and Biological Properties of Mesenchymal Stem Cells
B. Romano, S. Elangovan, M. Erreni, Emanuela Sala +17 more
2019Stem Cells43 citations Open access
Semantic Scholar
Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset
Chiara Milani, F. Farina, Laura Botto, Luca Massimino +7 more
2020International Journal of Molecular Sciences41 citations Open access
Semantic Scholar
GPR120 prevents colorectal adenocarcinoma progression by sustaining the mucosal barrier integrity
F. Rubbino, Valentina Garlatti, Valeria Garzarelli, Luca Massimino +11 more
2021Scientific Reports36 citations Open access
Semantic Scholar
The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.
A. Sessa, E. Ciabatti, Daniela Drechsel, Luca Massimino +6 more
2017Cerebral Cortex35 citations Open access
Semantic Scholar
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
P. Mazzara, Luca Massimino, Marta Pellegatta, G. Ronchi +12 more
2017Nature Communications34 citations Open access
Semantic Scholar
De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways
V. Magistroni, Mario Mauri, D. D’Aliberti, C. Mezzatesta +24 more
2019Haematologica31 citations Open access
Semantic Scholar
The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways
A. Sessa, E. Ciabatti, Daniela Drechsel, Luca Massimino +6 more
2016Cerebral Cortex31 citations Open access
Semantic Scholar
In Vivo Comparative Study on Acute and Sub-acute Biological Effects Induced by Ultrafine Particles of Different Anthropogenic Sources in BALB/c Mice
F. Farina, E. Lonati, Chiara Milani, Luca Massimino +9 more
2019International Journal of Molecular Sciences28 citations Open access
Semantic Scholar
Gut eukaryotic virome in colorectal carcinogenesis: Is that a trigger?
Luca Massimino, S. Lovisa, Luigi Antonio Lamparelli, S. Danese +1 more
2020Computational and Structural Biotechnology Journal27 citations Open access
Semantic Scholar
Changes in body composition during neoadjuvant therapy can affect prognosis in rectal cancer patients: An exploratory study.
P. De Nardi, M. Salandini, D. Chiari, N. Pecorelli +6 more
2019Current Problems in Cancer26 citations
Semantic Scholar
Direct Neuronal Reprogramming Reveals Unknown Functions for Known Transcription Factors
G. Colasante, Alicia Rubio, Luca Massimino, V. Broccoli
2019Frontiers in Neuroscience26 citations Open access
Semantic Scholar
Lymphatic endothelium contributes to colorectal cancer growth via the soluble matrisome component GDF11
F. Ungaro, P. Colombo, Luca Massimino, Giovanni Stefano Ugolini +15 more
2019International Journal of Cancer24 citations Open access
Semantic Scholar
Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia
D. Fontana, Daniele Ramazzotti, A. Aroldi, S. Redaelli +26 more
2020HemaSphere21 citations Open access
Semantic Scholar
Concomitant BCORL1 and BRAF Mutations in Vemurafenib-Resistant Melanoma Cells
L. Mologni, Mariantonia Costanza, G. Sharma, Michela Viltadi +8 more
2018Neoplasia20 citations Open access
Semantic Scholar
Author Correction: Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity
Simone Bido, Sharon Muggeo, Luca Massimino, M. Marzi +14 more
2021Nature Communications18 citations Open access
Semantic Scholar
TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway
G. Mastrototaro, M. Zaghi, Luca Massimino, Matteo Moneta +10 more
2021Frontiers in Cell and Developmental Biology18 citations Open access
Semantic Scholar
Early evidence of stress in immortalized neurons exposed to diesel particles: the role of lipid reshaping behind oxidative stress and inflammation.
Chiara Milani, P. Corsetto, F. Farina, Laura Botto +5 more
2018Toxicology17 citations
Semantic Scholar
Synergistic Drug Combinations Prevent Resistance in ALK+ Anaplastic Large Cell Lymphoma
Giulia Arosio, G. Sharma, M. Villa, Mario Mauri +15 more
2021Cancers16 citations Open access
Semantic Scholar
TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing ZFP423 during corticogenesis
Luca Massimino, Lisbeth Flores-García, B. D. Di Stefano, G. Colasante +4 more
2018Developmental Biology16 citations Open access
Semantic Scholar
ZFP423 regulates early patterning and multiciliogenesis in the hindbrain choroid plexus
F. Casoni, L. Croci, F. Vincenti, P. Podini +4 more
2020Development15 citations Open access
Semantic Scholar
mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn’s Disease
F. Ungaro, Valentina Garlatti, Luca Massimino, A. Spinelli +10 more
2019Cells15 citations Open access
Semantic Scholar
Altered expression of neuropeptides in FoxG1-null heterozygous mutant mice
E. Frullanti, Sonia Amabile, M. G. Lolli, Anna Bartolini +8 more
2015European Journal of Human Genetics14 citations Open access
Semantic Scholar
Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition
M. Zaghi, Federica Banfi, Luca Massimino, M. Volpin +19 more
2023Nature Communications13 citations Open access
Semantic Scholar
A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development
V. Benedetti, Federica Banfi, M. Zaghi, Raquel Moll-Diaz +10 more
2022Science Advances12 citations Open access
Semantic Scholar
Fatty Acid Profile and Antioxidant Status Fingerprint in Sarcopenic Elderly Patients: Role of Diet and Exercise
P. Corsetto, G. Montorfano, C. Klersy, Luca Massimino +8 more
2019Nutrients12 citations Open access
Semantic Scholar
In silico gene expression profiling in Cannabis sativa
Luca Massimino
2017F1000Research10 citations Open access
Semantic Scholar
SETD5 haploinsufficiency affects mitochondrial compartment in neural cells
M. Zaghi, Fabiana Longo, Luca Massimino, Alicia Rubio +9 more
2023Molecular Autism4 citations Open access
Semantic Scholar
Tailoring the radiotherapy approach in patients with anal squamous cell carcinoma based on inguinal sentinel lymph node biopsy
P. De Nardi, M. Mistrangelo, G. Burtulo, P. Passoni +10 more
2020Journal of Surgical Oncology4 citations
Semantic Scholar

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