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F. Pinna · SciRah

Researcher profile · Semantic Scholar

F. Pinna

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F. Pinna — researcher profile on SciRah

h-index: 16
Works: 46
Citations: 1,573

Most-cited papers

Yes-Associated Protein Upregulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma
D. Tschaharganeh, Xin Chen, Philipp Latzko, M. Malz +19 more
2013Gastroenterology291 citations Open access
Semantic Scholar
Curcumin effectively inhibits oncogenic NF-kB signaling and restrains stemness features in liver cancer
J. Marquardt, L. Gómez-Quiroz, Lucrecia O. Arreguin Camacho, F. Pinna +10 more
2015Journal of Hepatology269 citations Open access
Semantic Scholar
Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP.
K. Strassburger, Marcel Tiebe, F. Pinna, K. Breuhahn +1 more
2012Developmental Biology148 citations Open access
Semantic Scholar
Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.
S. Weiler, F. Pinna, T. Wolf, T. Lutz +19 more
2017Gastroenterology137 citations
Semantic Scholar
SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.
D. Calvisi, S. Ladu, F. Pinna, M. Frau +9 more
2009Gastroenterology126 citations Open access
Semantic Scholar
Dual-specificity phosphatase 1 ubiquitination in extracellular signal-regulated kinase-mediated control of growth in human hepatocellular carcinoma.
D. Calvisi, F. Pinna, Floriana Meloni, S. Ladu +12 more
2008Cancer Research114 citations Open access
Semantic Scholar
Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC
D. Calvisi, F. Pinna, S. Ladu, R. Pellegrino +8 more
2009Gut88 citations Open access
Semantic Scholar
Altered methionine metabolism and global DNA methylation in liver cancer: Relationship with genomic instability and prognosis
D. Calvisi, M. Simile, S. Ladu, R. Pellegrino +9 more
2007International Journal of Cancer82 citations
Semantic Scholar
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease.
D. Calvisi, F. Pinna, S. Ladu, R. Pellegrino +10 more
2008Carcinogenesis59 citations Open access
Semantic Scholar
Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness
S. Wan, A. Meyer, S. Weiler, C. Rupp +14 more
2018Hepatology54 citations
Semantic Scholar
Ras‐driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control
D. Calvisi, F. Pinna, R. Pellegrino, V. Sanna +10 more
2008International Journal of Cancer43 citations Open access
Semantic Scholar
Prosurvival function of the cellular apoptosis susceptibility/importin‐α1 transport cycle is repressed by p53 in liver cancer
J. Winkler, A. Ori, K. Holzer, C. Sticht +14 more
2014Hepatology34 citations Open access
Semantic Scholar
Transcriptional regulators in hepatocarcinogenesis--key integrators of malignant transformation.
M. Malz, F. Pinna, P. Schirmacher, K. Breuhahn
2012Journal of Hepatology29 citations Open access
Semantic Scholar
The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease
D. Calvisi, F. Pinna, S. Ladu, M. Muroni +8 more
2009International Journal of Cancer26 citations Open access
Semantic Scholar
A20/TNFAIP3 Discriminates Tumor Necrosis Factor (TNF)-Induced NF-κB from JNK Pathway Activation in Hepatocytes
F. Pinna, M. Bissinger, Katharina Beuke, Nicolas Huber +5 more
2017Frontiers in Physiology21 citations Open access
Semantic Scholar
Nuclear Expression of the Deubiquitinase CYLD Is Associated with Improved Survival in Human Hepatocellular Carcinoma
S. Welte, T. Urbanik, C. Elssner, Nicole Kautz +10 more
2014PLoS ONE20 citations Open access
Semantic Scholar
Dynamic YAP expression in the non-parenchymal liver cell compartment controls heterologous cell communication
Kaijing Liu, L. Wehling, Shan Wan, S. Weiler +25 more
2024Cellular and Molecular Life Sciences12 citations Open access
Semantic Scholar
A Systems Biology Study on NFκB Signaling in Primary Mouse Hepatocytes
F. Pinna, S. Sahle, Katharina Beuke, M. Bissinger +9 more
2012Front. Physio.8 citations Open access
Semantic Scholar
Identification and chromosome mapping of loci predisposing to colorectal cancer that control Wnt/beta-catenin pathway and progression of early lesions in the rat.
M. R. De Miglio, Patrizia Virdis, D. Calvisi, Daniela Mele +7 more
2007Carcinogenesis8 citations
Semantic Scholar
The Cell Polarity Protein MPP5/PALS1 Controls the Subcellular Localization of the Oncogenes YAP and TAZ in Liver Cancer
M. Tóth, Shan Wan, J. Schmitt, Patrizia Birner +8 more
2025International Journal of Molecular Sciences3 citations Open access
Semantic Scholar
Abstract 5235: A model for TNFα-mediated NFκB signalling: A systems biology study on hepatocytes and liver cancer cells.
F. Pinna, S. Sahle, Katharina Beuke, M. Bissinger +9 more
20132 citations
Semantic Scholar
The interaction of Serum Response Factor (SRF) and ETS domain transcription factors regulate the transcription of the MDM 4 oncogene in HCC
R. Pellegrino, A. Thavamani, D. Calvisi, A. Neumann +5 more
2019Zeitschrift für Gastroenterologie - German Journal of Gastroenterology1 citations
Semantic Scholar
Quantitative and integrative analysis of paracrine hepatocyte activation by nonparenchymal cells upon lipopolysaccharide induction
Katharina Beuke, F. Schildberg, F. Pinna, U. Albrecht +9 more
2017The FEBS Journal1 citations
Semantic Scholar
Abstract 4269: A gene signature defines chromosomal instability (CIN) and poor survival in liver cancer patients
S. Weiler, T. Wolf, F. Pinna, S. Roessler +6 more
20151 citations
Semantic Scholar
The cell polarity protein MPP5/PALS1 controls the subcellular localization of the oncogenes YAP and TAZ in hepatocellular carcinoma
M. Tóth, Shan Wan, Teng Wei, Fabian von Bubnoff +6 more
2025Zeitschrift für Gastroenterologie - German Journal of Gastroenterology0 citations
Semantic Scholar
Mutation of PRSS23 promotes HCC development via activation of AKT/PI3K/mTOR signaling
F. Pinna, Z. Abadi, O. Neumann, A. Neumann +7 more
2019Zeitschrift für Gastroenterologie - German Journal of Gastroenterology0 citations
Semantic Scholar
TAZ-inactivation partly compensates the phenotype caused by YAP knockdown in livers of YAP/TAZ-deficient mice
K. Liu, S. Weiler, S. Wan, M. Tóth +7 more
2019Zeitschrift für Gastroenterologie - German Journal of Gastroenterology0 citations
Semantic Scholar
Imbalance of scaffold proteins IQGAP1/IQGAP2 in Liver Cancer
F. Pinna, R. Pellegrino, A. Neumann, J. Baues +2 more
2018Zeitschrift für Gastroenterologie - German Journal of Gastroenterology0 citations
Semantic Scholar
Defining the LINC00152-modulated ceRNA network in human hepatocellular carcinoma
R. Pellegrino, F. Ticconi, B. Skawran, M. Castoldi +5 more
2018Zeitschrift für Gastroenterologie - German Journal of Gastroenterology0 citations
Semantic Scholar
Abstract 1130: Subcellular localization of the cell polarity protein Scribble defines its oncogenic activity in hepatocellular carcinoma
Shan Wan, A. Meyer, S. Weiler, T. Lutz +4 more
20160 citations
Semantic Scholar
Role of the IQGAP1/IQGAP2 imbalance in Liver Cancer
F. Pinna, R. Pellegrino, O. Neumann, J. Baues +4 more
2016Zeitschrift für Gastroenterologie - German Journal of Gastroenterology0 citations
Semantic Scholar
Implementation of systems theory in liver cancer research.
F. Pinna, K. Breuhahn
2015Hepatic Oncology0 citations Open access
Semantic Scholar
A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment
Katharina Beuke, F. Schildberg, F. Pinna, U. Albrecht +9 more
20150 citations
Semantic Scholar
Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1
S. Weiler, F. Pinna, T. Lutz, T. Wolf +10 more
20150 citations
Semantic Scholar
Identification of potential driver genes involved in chromosomal instability and tumor cell migration in hepatocarcinogenesis
A. Meyer, S. Wan, S. Weiler, S. Roessler +4 more
20150 citations
Semantic Scholar
A20(TNFAIP3) as modulator of TNFα-induced responses in mouse hepatoma cell lines and primary mouse hepatocytes
F. Pinna, M. Bissinger, P. Schirmacher, K. Breuhahn
20150 citations
Semantic Scholar
Gene signatures define chromosomal instability (CIN) and poor survival in HCC patients
S. Weiler, Thomas Wolf, F. Pinna, S. Rössler +6 more
20150 citations
Semantic Scholar
Loss of cell polarity defines a cancer-prone phenotype in liver epithelial cells
S. Wan, A. Meyer, S. Weiler, T. Lutz +5 more
20150 citations
Semantic Scholar
Cooperative function of YAP and TAZ in hepatocytes and hepatocarcinogenesis
T. Lutz, S. Weiler, F. Pinna, S. Wan +4 more
20150 citations
Semantic Scholar
Role of A20(TNFAIP3) in mediating TNFα-induced pathways activation in mouse hepatoma cell lines and primary hepatocytes
F. Pinna, M. Bissinger, P. Schirmacher, K. Breuhahn
20140 citations
Semantic Scholar
Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases
J. Marquardt, L. Gomez-Quirez, L. A. Camacho, F. Pinna +7 more
20140 citations
Semantic Scholar
Role of protein turnover in NF-κB signalling: A systems biology study on primary hepatocytes
F. Pinna, S. Sahle, Katharina Beuke, M. Bissinger +9 more
20130 citations
Semantic Scholar
A systems biology study on NF κ B signaling in primary mouse hepatocytes
F. Pinna, S. Sahle, Katharina Beuke, M. Bissinger +9 more
20120 citations
Semantic Scholar
Dissection TNFα/NF-κB signalling in murine hepatocytes–a model for the priming phase of liver regeneration
F. Pinna, Selcan Tuncay, L. D'Alessandro, R. Gauges +5 more
20120 citations
Semantic Scholar
Abstract 984: High-level expression of YAP induces protumorigenic Notch signalling in human hepatocarcinogenesis
D. Tschaharganeh, Xin-Cheng Chen, Philipp Latzko, M. Malz +17 more
20120 citations
Semantic Scholar
sustains ERK activity in human HCC susceptibility to hepatocarcinogenesis and Forkhead box M 1 B is a determinant of rat
F. Pinna, S. Ladu, R. Pellegrino, M. Simile +6 more
20090 citations
Semantic Scholar

Frequent co-authors

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K. Breuhahn×32
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K. Breuhahn — researcher profile on SciRah
P. Schirmacher×22
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P. Schirmacher — researcher profile on SciRah
S. Weiler×12
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S. Weiler — researcher profile on SciRah
M. Bissinger×12
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M. Bissinger — researcher profile on SciRah

×11

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D. Calvisi — researcher profile on SciRah

R. Pellegrino×11

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R. Pellegrino — researcher profile on SciRah

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M. Tomasi — researcher profile on SciRah

J. Marquardt×9

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J. Marquardt — researcher profile on SciRah

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S. Wan — researcher profile on SciRah

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M. Frau — researcher profile on SciRah

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M. Simile — researcher profile on SciRah

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M. Muroni — researcher profile on SciRah