Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Tye · SciRah

Researcher profile · Semantic Scholar

S. Tye

Share profile

S. Tye — researcher profile on SciRah

h-index: 22
Works: 39
Citations: 1,559

Most-cited papers

Evidence for a Significant Role of α3-Containing GABAA Receptors in Mediating the Anxiolytic Effects of Benzodiazepines
R. Dias, W. F. Sheppard, R. Fradley, E. Garrett +18 more
2005Journal of Neuroscience262 citations Open access
Semantic Scholar
TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates
J. Atack, K. Wafford, S. Tye, Susan M. Cook +14 more
2006Journal of Pharmacology and Experimental Therapeutics195 citations
Semantic Scholar
The novel NK1 receptor antagonist MK-0869 (L-754,030) and its water soluble phosphoryl prodrug, L-758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets.
F. Tattersall, W. Rycroft, M. Cumberbatch, G. Mason +12 more
2000Neuropharmacology135 citations
Semantic Scholar
Orexin Receptor Antagonists Differ from Standard Sleep Drugs by Promoting Sleep at Doses That Do Not Disrupt Cognition
Jason M. Uslaner, S. Tye, D. Eddins, Xiaohai Wang +17 more
2013Science Translational Medicine95 citations
Semantic Scholar
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold
Anthony L. Gotter, C. Winrow, J. Brunner, Susan L. Garson +16 more
2013BMC Neuroscience90 citations Open access
Semantic Scholar
Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist
J. Atack, D. Hallett, S. Tye, K. Wafford +17 more
2011Journal of Psychopharmacology58 citations Open access
Semantic Scholar
MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans
J. Atack, Keith A. Wafford, L. Street, G. R. Dawson +11 more
2011Journal of Psychopharmacology56 citations Open access
Semantic Scholar
Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in Monkeys.
P. Tannenbaum, S. Tye, J. Stevens, Anthony L. Gotter +8 more
2016Sleep51 citations Open access
Semantic Scholar
Differential sleep-promoting effects of dual orexin receptor antagonists and GABAA receptor modulators
Anthony L. Gotter, Susan L. Garson, J. Stevens, Regina L. Munden +10 more
2014BMC Neuroscience48 citations Open access
Semantic Scholar
Discovery of imidazo[1,2-b][1,2,4]triazines as GABA(A) alpha2/3 subtype selective agonists for the treatment of anxiety.
M. G. Russell, R. Carling, L. Street, D. Hallett +21 more
2006Journal of Medicinal Chemistry44 citations Open access
Semantic Scholar
Enhanced performance of spatial and visual recognition memory tasks by the selective acetylcholinesterase inhibitor E2020 in rhesus monkeys
N. Rupniak, S. Tye, M. J. Field
1997Psychopharmacology42 citations
Semantic Scholar
Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators
Andres D. Ramirez, Anthony L. Gotter, Steven V. Fox, P. Tannenbaum +13 more
2013Frontiers in Neuroscience41 citations Open access
Semantic Scholar
Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogs
P. Tannenbaum, J. Stevens, Jacquelyn Binns, Alan T. Savitz +10 more
2014Frontiers in Behavioral Neuroscience40 citations Open access
Semantic Scholar
Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABAA Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats
Steven V. Fox, Anthony L. Gotter, S. Tye, Susan L. Garson +13 more
2013Neuropsychopharmacology39 citations Open access
Semantic Scholar
Reversal of cognitive impairment by heptyl physostigmine, a long-lasting cholinesterase inhibitor, in primates.
N. M. J. Rupniak, S. Tye, C. Brazell, A. Heald +2 more
1992Journal of Neurological Sciences36 citations
Semantic Scholar
Evidence against a specific effect of cholinergic drugs on spatial memory in primates.
N. Rupniak, N. A. Samson, S. Tye, M. J. Field +1 more
1991Behavioural Brain Research36 citations
Semantic Scholar
The pharmacological properties of the imidazobenzodiazepine, FG 8205, a novel partial agonist at the benzodiazepine receptor
M. Tricklebank, T. Honoré, S. D. Iversen, John A. Kemp +7 more
1990British Journal of Pharmacology36 citations Open access
Semantic Scholar
Antiparkinsonian efficacy of a novel transdermal delivery system for (+)-PHNO in MPTP-treated squirrel monkeys
N. M. J. Rupniak, S. Tye, C. Jennings, A. Loper +5 more
1989Neurology33 citations
Semantic Scholar
Anxiolytic-like and antinociceptive effects of MK-801 accompanied by sedation and ataxia in primates.
N. Rupniak, S. Boyce, S. Tye, G. Cook +1 more
1993Pharmacology, Biochemistry and Behavior30 citations
Semantic Scholar
Blockade of CCK-B receptors by L-365,260 induces analgesia in the squirrel monkey.
Michael F. O'Neill, C. T. Dourish, S. Tye, S. D. Iversen
1990Brain Research27 citations
Semantic Scholar
A Pyridazine Series of α2/α3 Subtype Selective GABAA Agonists for the Treatment of Anxiety
Richard T. Lewis, W. Blackaby, T. Blackburn, Andrew S. R. Jennings +14 more
200626 citations Open access
Semantic Scholar
Failure of d-cycloserine to reverse cognitive disruption induced by scopolamine or phencyclidine in primates.
N. M. J. Rupniak, M. Duchnowski, S. Tye, G. Cook +1 more
1992Life Science25 citations
Semantic Scholar
Imidazo[1,2-b][1,2,4]triazines as α2/α3 subtype selective GABAA agonists for the treatment of anxiety
Andrew S. R. Jennings, Richard T. Lewis, M. G. Russell, D. Hallett +14 more
200619 citations Open access
Semantic Scholar
Comparison of the effects of selective and nonselective muscarinic agonists on cognition and thermoregulation in primates.
N. M. J. Rupniak, S. Tye, S. D. Iversen
1992Journal of Neurological Sciences18 citations
Semantic Scholar
Modulatory role for CCK-B antagonists in Parkinson's disease.
S. Boyce, N. Rupniak, S. Tye, M. Steventon +1 more
1990Clinical neuropharmacology16 citations
Semantic Scholar
Lack of effect of CCKB receptor antagonists in ethological and conditioned animal screens for anxiolytic drugs
G. Dawson, N. Rupniak, S. Iversen, R. Curnow +3 more
1995Psychopharmacology13 citations
Semantic Scholar
NB-355: a novel prodrug for L-DOPA with reduced risk for peak-dose dyskinesias in MPTP-treated squirrel monkeys.
S. Tye, N. M. J. Rupniak, T. Naruse, M. Miyaji +1 more
1989Clinical neuropharmacology10 citations
Semantic Scholar
A pyridazine series of alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.
Richard T. Lewis, W. Blackaby, T. Blackburn, Andrew S. R. Jennings +14 more
2006Journal of Medicinal Chemistry7 citations
Semantic Scholar
Spontaneous orofacial dyskinesias in a captive cynomolgus monkey: Implications for tardive dyskinesia
N. Rupniak, S. Tye, M. Steventon, S. Boyce +1 more
1990Movement Disorders6 citations
Semantic Scholar
Therapeutic efficacy of a novel transdermal delivery system for (+)-PHNO in parkinsonian squirrel monkeys.
N. M. J. Rupniak, S. Tye, C. Jennings, A. Loper +4 more
1989Journal of Neurology Neurosurgery & Psychiatry6 citations Open access
Semantic Scholar
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold
Anthony L. Gotter, C. Winrow, J. Brunner, Susan L. Garson +16 more
2013BMC Neuroscience4 citations Open access
Semantic Scholar
Imidazo[1,2-b][1,2,4]triazines as alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.
Andrew S. R. Jennings, Richard T. Lewis, M. G. Russell, D. Hallett +14 more
2006Bioorganic & Medicinal Chemistry Letters4 citations
Semantic Scholar
Drug-induced purposeless chewing: animal model of dyskinesia or nausea?
N. M. J. Rupniak, S. Tye, S. D. Iversen
2005Psychopharmacology4 citations
Semantic Scholar
Heptylphysostigmine — Novel Acetylcholinesterase Inhibitor: Biochemical and Behavioral Pharmacology
L. Iversen, G. Bentley, G. Dawson, S. Freedman +6 more
19914 citations
Semantic Scholar
Behavioral and qEEG effects of the PDE10A inhibitor THPP-1 in a novel rhesus model of antipsychotic activity
Joshua D. Vardigan, Henry S. Lange, S. Tye, Steven V. Fox +2 more
2016Psychopharmacology3 citations
Semantic Scholar
Differential sleep-promoting effects of dual orexin receptor antagonists and GABAAreceptor modulators
Anthony L. Gotter, Susan L. Garson, J. Stevens, Regina L. Munden +10 more
2014BMC Neuroscience2 citations Open access
Semantic Scholar
Assessment of an orexin-2 receptor (OX2R) PET tracer feasibility: [18F]A in vitro brain tissue based binding assay and in vivo PET imaging study
Wenping Li, Yuchuan Wang, Kerry Riffel, Patricia Miller +7 more
2025Nuclear Medicine and Biology0 citations
Semantic Scholar
P.6.d.006 The in vivo modulation of the mesolimbic dopamine system by cannabinoid CB1 receptors
J. Cornish, A. Wilson, S. Tye
20070 citations
Semantic Scholar
Assessment of Novel Sustained Release Antiparkinsonian Therapies in MPTP-Treated Primates
N. Rupniak, S. Tye, A. Loper, J. V. Bondi +3 more
19900 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Jason M. Uslaner×10
Invite
Jason M. Uslaner — researcher profile on SciRah
Steven V. Fox×10
Invite
Steven V. Fox — researcher profile on SciRah
J. Atack×9
Invite
J. Atack — researcher profile on SciRah
P. Tannenbaum×9
Invite
P. Tannenbaum — researcher profile on SciRah

Anthony L. Gotter

×9

Invite

Anthony L. Gotter — researcher profile on SciRah

Invite

S. Kuduk — researcher profile on SciRah

Paul J. Coleman×9

Invite

Paul J. Coleman — researcher profile on SciRah

Invite

C. Winrow — researcher profile on SciRah

Invite

J. Renger — researcher profile on SciRah

Invite

K. Wafford — researcher profile on SciRah

Susan L. Garson×8

Invite

Susan L. Garson — researcher profile on SciRah

Invite

T. McDonald — researcher profile on SciRah